Page last updated: 2024-08-24

nelfinavir and Pregnancy

nelfinavir has been researched along with Pregnancy in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (3.23)	18.2507
2000's	45 (72.58)	29.6817
2010's	13 (20.97)	24.3611
2020's	2 (3.23)	2.80

Authors

Authors	Studies
Chen, YC; Dumond, JB; Fiscus, SA; Horton, AL; Kashuba, AD; Patterson, KB; Rezk, NL; Tappouni, HL; Tien, HC; Vourvahis, M; Yeh, RF	1
Du, F; Feng, XL; Ge, G; Gong, L; Han, JB; Ji, J; Jiang, X; Li, C; Ling, Y; Lu, X; Peng, C; Shen, J; Shi, D; Song, TZ; Tian, RR; Wang, P; Wang, Z; Wu, C; Wu, J; Wu, N; Xu, Y; Xu, Z; Yang, J; Yao, H; Zang, Y; Zhang, J; Zhang, Y; Zheng, M; Zheng, YT; Zhu, M; Zhu, W	1
Fujii, Y; Fukushige, Y; Hanaoka, H; Hanawa, M; Hori, M; Hosogaya, N; Iwami, S; Izumikawa, K; Kawasaki, Y; Kohno, S; Kurokawa, T; Miyazaki, T; Miyazaki, Y; Morimoto, S; Mukae, H; Takemori, S; Wakita, T; Watashi, K; Yamagoe, S; Yamamoto, H; Yanagihara, K	1
Best, BM; Capparelli, EV; Eke, AC; Kreitchmann, R; McCormack, SA; Mirochnick, M; Mofenson, LM; Shapiro, D; Smith, E; Stek, AM; Wang, J	1
Boucoiran, I; Burchett, S; Frenkel, L; Gantt, S; Huang, ML; Jacobsen, DL; Jerome, KR; Jourdain, G; Leister, E; Ngo-Giang-Huong, N	1
Barr, E; Davies, J; Forster, JE; Kinzie, K; Levin, MJ; McFarland, EJ; Pappas, J; Paul, S; Smith, C; Weinberg, A	1
Blanche, S; Goujon, S; Hleyhel, M; Sibiude, J; Warszawski, J	1
Amici, R; Baroncelli, S; Cusato, M; Floridia, M; Galluzzo, CM; Molinari, A; Pinnetti, C; Pirillo, MF; Regazzi, M; Sabbatini, F; Tamburrini, E; Villani, P	1
Best, BM; Burchett, SK; Capparelli, EV; Febo, I; Holland, DT; Hu, C; Mirochnick, M; Read, JS; Shearer, WT; Sheeran, EC; Smith, ME; Stek, AM	1
Afonso, AO; Cunha, SM; Lemey, P; Machado, ES; Nissley, DV; Oliveira, RH; Soares, MA	1
Chung, F; Mirfazaelian, A; Naraharisetti, SB; Unadkat, JD; Whittington, D; Wu, X; Zhang, H	2
Gocke, E; Müller, L; Pfister, T	1
Anderson, JR; Argani, CH; Silva, AM; Stohl, HE	1
Beghin, D; Cayre, Y; Farinotti, R; Forestier, F; Gavard, L; Gil, S; Mandelbrot, L; Peytavin, G	1
Müller, L; Singer, T	1
Cheng, I; Kuritzkes, DR; Paredes, R; Tuomala, RE	2
Anceschi, MM; Ascenzi, P; Ivanovic, J; Mattia, E; Narciso, P; Nicastri, E; Notari, S; Pisani, G; Pucillo, LP; Signore, F; Tempestilli, M; Vallone, C	1
Beghin, D; Farinotti, R; Forestier, F; Gavard, L; Gil, S; Guibourdenche, J; Noël-Hudson, MS	1
Ellis, GM; Frenkel, LM; Hitti, J; Huang, S	1
Antonio, EM; de Carvalho, GM; Fontes, TM; Kulay Júnior, L; Nakamura, MU; Simões, RS; Wagngner, A	1
Angira, F; Girde, S; Lando, R; Martin, A; Minniear, TD; Ogindo, P; Osoga, J; Thomas, TK; Weidle, PJ; Zeh, C	1
Boer, K; Godfried, MH; Nellen, J; Scherpbier, H; van Hoog, S	1
Bastos, FI; Bethel, J; Bryson, YJ; Camarca, M; Ceriotto, M; Dickover, R; Fonseca, R; Gray, G; Grinsztejn, B; Joao, EC; Kreitchmann, R; Machado, D; Mirochnick, M; Mofenson, LM; Moreira, RI; Morgado, MG; Moye, J; Mussi-Pinhata, MM; Nielsen-Saines, K; Pilotto, JH; Pinto, J; Santos, B; Siberry, G; Theron, G; Veloso, VG; Watts, DH; Xu, J	1
Akoth, B; Angira, F; Masaba, R; Mills, LA; Minniear, TD; Ndivo, R; Oyaro, B; Peters, PJ; Polle, N; Thomas, TK; Zeh, C	1
Aweeka, FT; Beckerman, KP; Hayashi, S; Homma, M; Kosel, BW	1
Burns-Naas, LA; Holson, JF; Masarjian, L; Stump, DG; Webber, S; Zorbas, M	1
Burns-Naas, LA; Furman, G; Holson, JF; Masarjian, L; Stump, DG; Webber, S; Zorbas, M	1
Conner, SD; Covington, DL; Daniels, EM; Doi, PA; Swinson, J	1
Baker, D; Foca, M; Frenkel, LM; Gandia, J; Gonzalez-Garcia, A; Hitti, J; Huang, S; McNamara, J; Nachman, SA; Paul, ME; Provisor, A; Stek, AM; Stevens, LM; Thorpe, EM; Watts, DH; Wei, LJ	1
Chappuy, H; Dimet, J; Firtion, G; Fouché, M; Mandelbrot, L; Pons, G; Rey, E; Tréluyer, JM	1
Bergshoeff, AS; Boer, K; Burger, DM; Godfried, MH; Lange, JM; Nellen, JF; Prins, JM; Schillevoort, I; Wit, FW	1
Burger, DM; Grintjes, KJ; Koopmans, PP; Lotgering, FK	1
Beckerman, K; Chavers, S; Covington, DL; Dominguez, K; Garcia, P; Ross, B; Sacks, S; Scheuerle, A; Tilson, H; Watts, DH	1
Boer, K; Dieleman, JP; Godfried, MH; Tempelman, C; Timmermans, S; van der Ende, ME	1
Bourbeau, M; Cameron, DW; Gallicano, KD; Khaliq, Y; Phillips, EJ; Seguin, I; van Heeswijk, RP	1
Boer, K; de Wolf, F; Dieleman, J; Godfried, MH; Nellen, J; Schneider, ME; Sprenger, H; Tempelman, C; Timmermans, S; van der Ende, ME	1
Acevedo, M; Bryson, Y; Capparelli, E; Connor, J; Holland, D; Huang, S; Hughes, M; Keller, M; Mirochnick, M; Mofenson, L; Stek, A; Watts, H	1
Abduch, R; Duarte, G; El Beitune, P; Figueiró-Filho, EA; Machado, AA; Quintana, SM	1
Cvetković, RS; Frampton, JE; McCormack, PL; Perry, CM; Siddiqui, MA	1
Gupta, A; Lai, Y; Maggio-Price, L; Mathias, AA; Unadkat, JD	1
Amed, AM; Kulay, L; Mathias, CF; Mathias, CV; Oliveira-Filho, RM; Simões, MJ; Simões, RS	1
Chappuy, H; Firtion, G; Hirt, D; Jullien, V; Mandelbrot, L; Pons, G; Rey, E; Treluyer, JM; Urien, S	2
Olmo, M; Podzamczer, D	1
Cavaliere, AF; Cusato, M; degli Antoni, A; Floridia, M; Guaraldi, G; Molinari, A; Pirillo, MF; Regazzi, M; Tamburrini, E; Vanzini, C; Villani, P	1
Campbell, O; de Morais, EN; Duarte, G; El-Beitune, P; Mauad-Filho, F; Quintana, SM; Rodrigues, LC; Spara-Gadelha, P	1
Campbell, O; Duarte, G; El Beitune, P; Quintana, SM; Rodrigues, LC	1
Aguiar, RA; Aleixo, A; Cleto, S; Kakehasi, FM; Lin, E; Melo, VH; Pinto, JA; Tupinambás, U	1
Burri, M; Nadal, D; Rode, R; Rudin, C; Shen, Y	1
Temesgen, Z; Wright, AJ	1
Clumeck, N; DelFraissy, JF; DeLora, P; Duff, F; Johnson, M; Moyle, G; Opravil, M; Pelgrom, J; Pozniak, A; Reynes, J; Salgo, M; Vittecoq, D	1
Butler, KM; Clarke, SM; Condon, S; Healy, CM; Mulcahy, F	1
Chieco-Bianchi, L; De Rossi, A; Del Mistro, A; Giaquinto, C; Zamarchi, R	1
Angel, JB; Cameron, DW; Gallicano, K; Khaliq, Y; Monpetit, ML	1
Clark, RA; Kopicko, J; O'Brien, M; Reiss, G	1

Reviews

3 review(s) available for nelfinavir and Pregnancy

Article	Year
Nelfinavir: a review of its use in the management of HIV infection. Drugs, 2005, Volume: 65, Issue:15 Topics: Anti-Retroviral Agents; Drug Resistance, Viral; Female; HIV Infections; HIV Protease Inhibitors; Humans; Molecular Structure; Nelfinavir; Pregnancy; Salvage Therapy; Treatment Outcome	2005
A review of nelfinavir for the treatment of HIV infection. Expert opinion on drug metabolism & toxicology, 2006, Volume: 2, Issue:2 Topics: Female; HIV Infections; Humans; Molecular Structure; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Protease Inhibitors; Treatment Outcome	2006
Antiretrovirals. Mayo Clinic proceedings, 1999, Volume: 74, Issue:12 Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; Female; Furans; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Pregnancy; Pregnancy Complications, Infectious; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Sulfonamides; Zalcitabine; Zidovudine	1999

Trials

7 trial(s) available for nelfinavir and Pregnancy

Article	Year
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal transduction and targeted therapy, 2023, 04-24, Volume: 8, Issue:1 Topics: Animals; Antiviral Agents; China; COVID-19; Female; HIV Infections; Humans; Macaca mulatta; Nelfinavir; Pregnancy; Prospective Studies; SARS-CoV-2	2023
Efficacy and safety of nelfinavir in asymptomatic and mild COVID-19 patients: a structured summary of a study protocol for a multicenter, randomized controlled trial. Trials, 2021, Apr-28, Volume: 22, Issue:1 Topics: COVID-19 Drug Treatment; COVID-19 Vaccines; Female; HIV Infections; Humans; Japan; Male; Middle Aged; Multicenter Studies as Topic; Nelfinavir; Pregnancy; Randomized Controlled Trials as Topic; SARS-CoV-2; Treatment Outcome	2021
Pharmacokinetics of Increased Nelfinavir Plasma Concentrations in Women During Pregnancy and Postpartum. Journal of clinical pharmacology, 2019, Volume: 59, Issue:3 Topics: Adult; Anti-HIV Agents; Female; HIV Protease Inhibitors; Humans; Nelfinavir; Postpartum Period; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies	2019
Three postpartum antiretroviral regimens to prevent intrapartum HIV infection. The New England journal of medicine, 2012, Jun-21, Volume: 366, Issue:25 Topics: Anti-Retroviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant Formula; Infant, Newborn; Infectious Disease Transmission, Vertical; Kaplan-Meier Estimate; Lamivudine; Male; Nelfinavir; Nevirapine; Postpartum Period; Pregnancy; Pregnancy Complications, Infectious; Zidovudine	2012
Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022. Journal of acquired immune deficiency syndromes (1999), 2004, Jul-01, Volume: 36, Issue:3 Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Infant, Newborn; Liver Failure, Acute; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Safety; Stevens-Johnson Syndrome	2004
Safety and pharmacokinetics of nelfinavir coadministered with zidovudine and lamivudine in infants during the first 6 weeks of life. Journal of acquired immune deficiency syndromes (1999), 2005, Jun-01, Volume: 39, Issue:2 Topics: Cohort Studies; Female; Gestational Age; HIV Protease Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious	2005
The SPICE study: 48-week activity of combinations of saquinavir soft gelatin and nelfinavir with and without nucleoside analogues. Study of Protease Inhibitor Combinations in Europe. Journal of acquired immune deficiency syndromes (1999), 2000, Feb-01, Volume: 23, Issue:2 Topics: Adult; CD4 Lymphocyte Count; Cohort Studies; Drug Therapy, Combination; Europe; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Nelfinavir; Pregnancy; RNA, Viral; Saquinavir	2000

Other Studies

52 other study(ies) available for nelfinavir and Pregnancy

Article	Year
Genital tract, cord blood, and amniotic fluid exposures of seven antiretroviral drugs during and after pregnancy in human immunodeficiency virus type 1-infected women. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Adult; Amniotic Fluid; Anti-HIV Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Fetal Blood; Genitalia, Female; HIV-1; Humans; Hydrocortisone; Pregnancy; Pregnancy Complications, Infectious; RNA, Viral	2009
Risk of congenital cytomegalovirus infection among HIV-exposed uninfected infants is not decreased by maternal nelfinavir use during pregnancy. Journal of medical virology, 2016, Volume: 88, Issue:6 Topics: Adult; CD4-Positive T-Lymphocytes; Cohort Studies; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Mothers; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Prevalence; Risk Factors; Young Adult	2016
Maternal Lopinavir/Ritonavir Is Associated with Fewer Adverse Events in Infants than Nelfinavir or Atazanavir. Infectious diseases in obstetrics and gynecology, 2016, Volume: 2016 Topics: Atazanavir Sulfate; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lopinavir; Male; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Retrospective Studies; Ritonavir	2016
In-utero exposure to nelfinavir-ethyl methyl sulfone. AIDS (London, England), 2016, 11-13, Volume: 30, Issue:17 Topics: Adolescent; Child; Child, Preschool; Congenital Abnormalities; Drug Contamination; Ethyl Methanesulfonate; Female; Follow-Up Studies; France; HIV Protease Inhibitors; Humans; Infant; Infant, Newborn; Male; Maternal-Fetal Exchange; Mutagens; Nelfinavir; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies	2016
Trough concentrations of lopinavir, nelfinavir, and nevirapine with standard dosing in human immunodeficiency virus-infected pregnant women receiving 3-drug combination regimens. Therapeutic drug monitoring, 2008, Volume: 30, Issue:5 Topics: Adolescent; Adult; Antiretroviral Therapy, Highly Active; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; Humans; Lopinavir; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Viral Load; Young Adult	2008
Pharmacokinetics of new 625 mg nelfinavir formulation during pregnancy and postpartum. HIV medicine, 2008, Volume: 9, Issue:10 Topics: Adolescent; Adult; Area Under Curve; CD4 Lymphocyte Count; Drug Administration Schedule; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infant, Newborn; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Puerperal Infection; RNA, Viral; Viral Load; Young Adult	2008
Emergence of primary NNRTI resistance mutations without antiretroviral selective pressure in a HAART-treated child. PloS one, 2009, Volume: 4, Issue:3 Topics: Adult; Antiretroviral Therapy, Highly Active; Didanosine; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation, Missense; Nelfinavir; Phylogeny; Point Mutation; Pregnancy; Pregnancy Complications, Infectious; Selection, Genetic; Zidovudine	2009
As in humans, pregnancy increases the clearance of the protease inhibitor nelfinavir in the nonhuman primate Macaca nemestrina. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3 Topics: Administration, Oral; Animals; Biological Availability; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Female; HIV Protease Inhibitors; Injections, Intra-Arterial; Intestine, Small; Liver; Macaca nemestrina; NADP; Nelfinavir; Pregnancy; Recombinant Proteins; Subcellular Fractions	2009
EMS in Viracept--initial ('traditional') assessment of risk to patients based on linear dose response relations. Toxicology letters, 2009, Nov-12, Volume: 190, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents, Alkylating; Carcinogenicity Tests; Dose-Response Relationship, Drug; Drug Contamination; Ethyl Methanesulfonate; Female; Genes, Dominant; Genes, Lethal; Germ-Line Mutation; HIV Protease Inhibitors; Humans; Linear Models; Mammary Neoplasms, Animal; Methyl Methanesulfonate; Mice; Mutagenicity Tests; Nelfinavir; No-Observed-Adverse-Effect Level; Pregnancy; Quantitative Structure-Activity Relationship; Rats; Risk Assessment	2009
Fulminant hepatic failure associated with antiretroviral therapy in a pregnant woman. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2009, Volume: 106, Issue:3 Topics: Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Infant, Newborn; Liver Failure, Acute; Liver Transplantation; Male; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Premature Birth; Protease Inhibitors; Young Adult	2009
Pregnancy does not increase CYP3A or P-glycoprotein activity in the non-human primate, Macaca nemestrina. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 330, Issue:2 Topics: Animals; Animals, Newborn; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Enzyme Activation; Female; HIV Protease Inhibitors; Macaca nemestrina; Midazolam; Nelfinavir; Pregnancy; Pregnancy Proteins; Pregnancy, Animal	2009
Contribution and limit of the model of perfused cotyledon to the study of placental transfer of drugs. Example of a protease inhibitor of HIV: nelfinavir. European journal of obstetrics, gynecology, and reproductive biology, 2009, Volume: 147, Issue:2 Topics: Female; HIV Protease Inhibitors; Humans; Maternal-Fetal Exchange; Nelfinavir; Perfusion; Placenta; Pregnancy; Protein Binding	2009
EMS in Viracept--the course of events in 2007 and 2008 from the non-clinical safety point of view. Toxicology letters, 2009, Nov-12, Volume: 190, Issue:3 Topics: Adult; Animals; Dose-Response Relationship, Drug; Drug and Narcotic Control; Drug Contamination; Drug-Related Side Effects and Adverse Reactions; Ethyl Methanesulfonate; European Union; Female; History, 21st Century; HIV Protease Inhibitors; Humans; Mice; Mutagenicity Tests; Mutagens; Nelfinavir; No-Observed-Adverse-Effect Level; Pregnancy; Product Surveillance, Postmarketing; Rats; Registries; Risk Assessment	2009
Postpartum antiretroviral drug resistance in HIV-1-infected women receiving pregnancy-limited antiretroviral therapy. AIDS (London, England), 2010, Jan-02, Volume: 24, Issue:1 Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine	2010
Transplacental transfer of antiretroviral drugs and newborn birth weight in HIV-infected pregnant women. Current HIV research, 2009, Volume: 7, Issue:6 Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Apgar Score; Atazanavir Sulfate; Birth Weight; Female; Gestational Age; HIV Infections; Humans; Infant, Newborn; Lopinavir; Maternal-Fetal Exchange; Nelfinavir; Nevirapine; Oligopeptides; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyridines; Pyrimidinones	2009
Modulation of endocrine and transport functions in human trophoblasts by saquinavir and nelfinavir. European journal of obstetrics, gynecology, and reproductive biology, 2010, Volume: 152, Issue:1 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Caveolin 1; Chorionic Gonadotropin; Female; Giant Cells; HIV Protease Inhibitors; Humans; Maternal-Fetal Relations; Nelfinavir; Pregnancy; Saquinavir; Trophoblasts	2010
Selection of HIV resistance associated with antiretroviral therapy initiated due to pregnancy and suspended postpartum. Journal of acquired immune deficiency syndromes (1999), 2011, Nov-01, Volume: 58, Issue:3 Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Microbial Sensitivity Tests; Nelfinavir; Nevirapine; Postpartum Period; Pregnancy; Pregnancy Complications, Infectious; Selection, Genetic	2011
[Effects of daily administration of a stavudine/nelfinavir association on the fetuses and placentas of female albino rats]. Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2011, Volume: 33, Issue:5 Topics: Animals; Anti-HIV Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Fetus; Nelfinavir; Placenta; Pregnancy; Rats; Rats, Wistar; Stavudine	2011
Nelfinavir and its active metabolite, hydroxy-t-butylamidenelfinavir (M8), are transferred in small quantities to breast milk and do not reach biologically significant concentrations in breast-feeding infants whose mothers are taking nelfinavir. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:11 Topics: Adult; Anti-HIV Agents; Breast Feeding; Female; Humans; Milk, Human; Nelfinavir; Pregnancy; Young Adult	2011
Transplacental passage of nevirapine, nelfinavir and lopinavir. The Netherlands journal of medicine, 2012, Volume: 70, Issue:2 Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Female; Fetal Blood; HIV Infections; Humans; Lopinavir; Maternal-Fetal Exchange; Nelfinavir; Nevirapine; Pregnancy	2012
Rash, hepatotoxicity and hyperbilirubinemia among Kenyan infants born to HIV-infected women receiving triple-antiretroviral drugs for the prevention of mother-to-child HIV transmission. The Pediatric infectious disease journal, 2012, Volume: 31, Issue:11 Topics: Adult; Aging, Premature; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; HIV Infections; Humans; Hyperbilirubinemia; Infant, Newborn; Infectious Disease Transmission, Vertical; Kenya; Nelfinavir; Nevirapine; Pregnancy	2012
Toxicology and carcinogenesis studies of mixtures of 3'-azido-3'-deoxythymidine (AZT), lamivudine (3TC), nevirapine (NVP), and nelfinavir mesylate (NFV) (Cas Nos. 30516-87-1, 134678-17-4, 129618-40-2, 159989-65-8) in B6C3F1 Mice (transplacental exposure s National Toxicology Program technical report series, 2013, Issue:569 Topics: Administration, Oral; Animals; Anti-Retroviral Agents; DNA; Drug Therapy, Combination; Escherichia coli; Female; Lamivudine; Longevity; Male; Maternal Exposure; Mice; Mice, Inbred Strains; Nelfinavir; Nevirapine; Pregnancy; Prenatal Exposure Delayed Effects; Salmonella typhimurium; Skin Neoplasms; Zidovudine	2013
Pharmacokinetics of nelfinavir and indinavir in HIV-1-infected pregnant women. AIDS (London, England), 2003, May-23, Volume: 17, Issue:8 Topics: Adult; Female; Gestational Age; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hydrocortisone; Indinavir; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Viral Load	2003
Absence of embryo-fetal toxicity in rats or rabbits following oral dosing with nelfinavir. Regulatory toxicology and pharmacology : RTP, 2003, Volume: 38, Issue:3 Topics: Administration, Oral; Animals; Animals, Newborn; Drug Evaluation, Preclinical; Embryonic and Fetal Development; Female; Fetus; Maternal-Fetal Exchange; Nelfinavir; Pregnancy; Pregnancy, Animal; Rabbits; Rats	2003
Absence of reproductive and developmental toxicity in rats following oral dosing with nelfinavir. Regulatory toxicology and pharmacology : RTP, 2003, Volume: 38, Issue:3 Topics: Administration, Oral; Animals; Animals, Newborn; Drug Evaluation, Preclinical; Embryonic and Fetal Development; Female; Fertility; Fetus; Lactation; Male; Maternal-Fetal Exchange; Micrognathism; Nelfinavir; Pregnancy; Rats; Rats, Sprague-Dawley; Reproduction; Time Factors; Tongue	2003
Risk of birth defects associated with nelfinavir exposure during pregnancy. Obstetrics and gynecology, 2004, Volume: 103, Issue:6 Topics: Abnormalities, Drug-Induced; Anti-HIV Agents; Birth Weight; Cohort Studies; Female; Gestational Age; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prevalence; Prospective Studies; Registries; Risk	2004
Maternal-fetal transfer and amniotic fluid accumulation of protease inhibitors in pregnant women who are infected with human immunodeficiency virus. American journal of obstetrics and gynecology, 2004, Volume: 191, Issue:2 Topics: Adult; Amniotic Fluid; Carbamates; Drug Therapy, Combination; Female; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Maternal-Fetal Exchange; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Ritonavir; Saquinavir; Sulfonamides	2004
Nelfinavir plasma concentrations are low during pregnancy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Sep-01, Volume: 39, Issue:5 Topics: Adult; Confounding Factors, Epidemiologic; Drug Administration Schedule; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infectious Disease Transmission, Vertical; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third	2004
[HAART and pregnancy. Nelfinavir superiority in hepatotoxicity]. MMW Fortschritte der Medizin, 2004, Apr-26, Volume: 146 Spec No 1 Topics: Abnormalities, Drug-Induced; Animals; Antiretroviral Therapy, Highly Active; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Female; HIV Infections; Humans; Infant, Newborn; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Risk Assessment	2004
Therapeutic drug monitoring of nelfinavir in pregnancy: a case report. Therapeutic drug monitoring, 2004, Volume: 26, Issue:5 Topics: Adult; Drug Monitoring; Female; HIV Infections; HIV Protease Inhibitors; Humans; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Viral Load	2004
Assessing the risk of birth defects associated with antiretroviral exposure during pregnancy. American journal of obstetrics and gynecology, 2004, Volume: 191, Issue:3 Topics: Abnormalities, Drug-Induced; Anti-Retroviral Agents; Female; Gestational Age; Humans; Lamivudine; Maternal-Fetal Exchange; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Outcome; Prospective Studies; Risk Factors; Stavudine; Zidovudine	2004
Antiretroviral treatment. HIV infection in adults: better-defined first-line treatment. Prescrire international, 2004, Volume: 13, Issue:72 Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Nelfinavir; Oligopeptides; Organophosphonates; Oxazines; Pregnancy; Pyrimidinones; Ritonavir; Stavudine; Sulfonamides; Treatment Outcome; Viral Load; Zidovudine	2004
[Highly active antiretroviral therapy (HAART) in HIV-positive pregnant women in the Netherlands, 1997-2003: safe, effective and with few side effects]. Nederlands tijdschrift voor geneeskunde, 2004, Oct-09, Volume: 148, Issue:41 Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Female; Fetus; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Nelfinavir; Netherlands; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Treatment Outcome; Viral Load	2004
The pharmacokinetics of nelfinavir and M8 during pregnancy and post partum. Clinical pharmacology and therapeutics, 2004, Volume: 76, Issue:6 Topics: Adult; Anti-HIV Agents; Chromatography, High Pressure Liquid; Female; Fetal Blood; Half-Life; Humans; Longitudinal Studies; Mass Spectrometry; Nelfinavir; Postpartum Period; Pregnancy	2004
Nelfinavir and nevirapine side effects during pregnancy. AIDS (London, England), 2005, May-20, Volume: 19, Issue:8 Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Female; HIV Infections; HIV Protease Inhibitors; Humans; Hyperglycemia; Nausea; Nelfinavir; Netherlands; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors	2005
Effect of antiretroviral drugs on maternal CD4 lymphocyte counts, HIV-1 RNA levels, and anthropometric parameters of their neonates. Clinics (Sao Paulo, Brazil), 2005, Volume: 60, Issue:3 Topics: Adolescent; Adult; Anti-HIV Agents; Birth Weight; Case-Control Studies; CD4 Lymphocyte Count; Female; Fetal Development; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; RNA, Viral; Zidovudine	2005
Changes in pharmacokinetics of anti-HIV protease inhibitors during pregnancy: the role of CYP3A and P-glycoprotein. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:3 Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Female; HIV Protease Inhibitors; Mice; Nelfinavir; Pregnancy; Pregnancy, Animal	2006
Safety of nelfinavir use during pregnancy. An experimental approach in rats. Clinical and experimental obstetrics & gynecology, 2005, Volume: 32, Issue:3 Topics: Animals; Female; HIV Infections; HIV Protease Inhibitors; Kidney; Liver; Male; Nelfinavir; Pregnancy; Pregnancy Outcome; Random Allocation; Rats; Rats, Wistar; Specific Pathogen-Free Organisms	2005
Pregnancy-related effects on nelfinavir-M8 pharmacokinetics: a population study with 133 women. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6 Topics: Adult; Bayes Theorem; Delivery, Obstetric; Dose-Response Relationship, Drug; Drug Monitoring; Female; HIV Protease Inhibitors; Humans; Models, Statistical; Nelfinavir; Pregnancy; Retrospective Studies	2006
Pharmacokinetics of nelfinavir in HIV-1-infected pregnant and nonpregnant women. British journal of clinical pharmacology, 2006, Volume: 62, Issue:3 Topics: Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third	2006
Antiretroviral agents and acid-base balance at delivery of the neonate. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2007, Volume: 40, Issue:7 Topics: Acid-Base Equilibrium; Adult; Anti-HIV Agents; Case-Control Studies; Drug Therapy, Combination; Female; Fetal Blood; HIV Infections; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nelfinavir; Pregnancy; Pregnancy Outcome; Prospective Studies; Zidovudine	2007
Effects of antiretroviral agents during pregnancy on liver enzymes and amylase in HIV-exposed, uninfected newborn infants. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2007, Volume: 11, Issue:3 Topics: Adolescent; Adult; Amylases; Anti-HIV Agents; Cohort Studies; Control Groups; Drug Therapy, Combination; Female; Fetal Blood; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Liver; Male; Nelfinavir; Pregnancy; Prospective Studies; Transaminases; Zidovudine	2007
High prevalence of primary lamivudine and nelfinavir resistance in HIV-1-infected pregnant women in the United States, 1998-2004. AIDS (London, England), 2007, Oct-01, Volume: 21, Issue:15 Topics: Adolescent; Adult; Drug Resistance, Viral; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Prevalence; Reverse Transcriptase Inhibitors; United States	2007
Pharmacokinetic modelling of the placental transfer of nelfinavir and its M8 metabolite: a population study using 75 maternal-cord plasma samples. British journal of clinical pharmacology, 2007, Volume: 64, Issue:5 Topics: Amniotic Fluid; Dose-Response Relationship, Drug; Female; Fetal Blood; HIV Infections; HIV Protease Inhibitors; Humans; Nelfinavir; Placenta; Pregnancy; Pregnancy Complications, Infectious; Treatment Outcome	2007
Persistence of genotypic resistance to nelfinavir among women exposed to prophylactic antiretroviral therapy during pregnancy. AIDS research and human retroviruses, 2007, Volume: 23, Issue:12 Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zidovudine	2007
Long-term safety and effectiveness of ritonavir, nelfinavir, and lopinavir/ritonavir in antiretroviral-experienced HIV-infected children. The Pediatric infectious disease journal, 2008, Volume: 27, Issue:5 Topics: Adolescent; CD4 Lymphocyte Count; Child; Child, Preschool; Cohort Studies; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infant; Infant, Newborn; Longitudinal Studies; Lopinavir; Male; Nelfinavir; Pregnancy; Pyrimidinones; Ritonavir; Switzerland; Treatment Outcome; Viral Load; Withholding Treatment	2008
Caution regarding nelfinavir use in children and pregnant women. AIDS clinical care, 2007, Volume: 19, Issue:11 Topics: Child; Female; HIV Protease Inhibitors; Humans; Nelfinavir; Pregnancy	2007
The efficacy and tolerability of combination antiretroviral therapy in pregnancy: infant and maternal outcome. International journal of STD & AIDS, 2000, Volume: 11, Issue:4 Topics: Adolescent; Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Infant; Lamivudine; Male; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Outcome; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Treatment Outcome; Zidovudine	2000
Onset of HIV-1 antibody production after highly active antiretroviral therapy in a seronegative HIV-1-infected child. AIDS (London, England), 2000, Jun-16, Volume: 14, Issue:9 Topics: Anti-HIV Agents; Antibody Formation; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Antibodies; HIV Infections; HIV Seronegativity; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Viremia; Zidovudine	2000
An argument for routine therapeutic drug monitoring of HIV-1 protease inhibitors during pregnancy. AIDS (London, England), 2001, Feb-16, Volume: 15, Issue:3 Topics: Adult; Anti-HIV Agents; Drug Monitoring; Female; HIV Protease Inhibitors; HIV-1; Humans; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; RNA, Viral; Viral Load	2001
New developments in women and AIDS research. Project Inform perspective, 1997, Issue:22 Topics: AIDS-Related Opportunistic Infections; Delavirdine; Drug Therapy, Combination; Estrogens; Female; HIV Infections; HIV Protease Inhibitors; HIV Wasting Syndrome; Humans; Indoles; Infant; Infectious Disease Transmission, Vertical; Isoquinolines; Nelfinavir; Piperazines; Pregnancy; Pregnancy Complications, Infectious; Progesterone; Sulfonic Acids; Zidovudine	1997
Lack of association between pregnancy and selected gastrointestinal adverse events among women prescribed nelfinavir. Journal of acquired immune deficiency syndromes (1999), 2001, Apr-15, Volume: 26, Issue:5 Topics: Adolescent; Adult; Female; Gastrointestinal Diseases; HIV Infections; HIV Protease Inhibitors; Humans; Middle Aged; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious	2001