Compounds > nelfinavir
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nelfinavir and Lung Neoplasms

nelfinavir has been researched along with Lung Neoplasms in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's2 (22.22)24.3611
2020's4 (44.44)2.80

Authors

AuthorsStudies
Besse, A; Besse, L; Driessen, C; Kraus, M; Tarantino, I1
Das, M1
Goyal, M; Gupta, V; Kulkarni, NS; Parvathaneni, V; Shukla, SK1
Connis, N; Dennis, PA; Gills, JJ; Hann, CL; Kawabata, S1
He, F; Huang, Z; Wang, G; Xu, Z1
Asuncion, A; Berry, GJ; Chapman, CH; Dimmick, KW; Filion, EJ; Green, J; Hara, W; Loo, BW; Marko, D; Shen, J; Tran, PT; Wakelee, H1
Evans, TL; Friedberg, J; Hahn, SM; Kucharczuk, J; Langer, CJ; Lin, LL; Maity, AM; Mick, R; Prendergast, S; Pryma, D; Rengan, R; Rosen, MA; Sharkoski, T; Stevenson, JP1
Bernhard, EJ; Cerniglia, GJ; Evans, SM; Gupta, AK; Hahn, SM; Jiang, Z; Koch, CJ; Maity, A; Pore, N1
Adachi, Y; Bandobashi, K; Ikezoe, T; Kobayashi, M; Koeffler, HP; Nishioka, C; Taguchi, H; Takeuchi, S; Takeuchi, T; Yang, Y1

Trials

1 trial(s) available for nelfinavir and Lung Neoplasms

ArticleYear
A phase I trial of the HIV protease inhibitor nelfinavir with concurrent chemoradiotherapy for unresectable stage IIIA/IIIB non-small cell lung cancer: a report of toxicities and clinical response.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2012, Volume: 7, Issue:4

    Topics: Aged; Carcinoma, Non-Small-Cell Lung; Female; Follow-Up Studies; HIV Protease Inhibitors; Humans; Lung Neoplasms; Male; Middle Aged; Nelfinavir; Neoplasm Staging; Phosphoinositide-3 Kinase Inhibitors; Tomography, X-Ray Computed

2012

Other Studies

8 other study(ies) available for nelfinavir and Lung Neoplasms

ArticleYear
The cytotoxic activity of carfilzomib together with nelfinavir is superior to the bortezomib/nelfinavir combination in non-small cell lung carcinoma.
    Scientific reports, 2023, 03-17, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Bortezomib; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Humans; Lung Neoplasms; Multiple Myeloma; Nelfinavir; Proteasome Endopeptidase Complex; Proteasome Inhibitors

2023
Nelfinavir with concurrent chemoradiotherapy in NSCLC.
    The Lancet. Oncology, 2019, Volume: 20, Issue:10

    Topics: Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Clinical Trials, Phase I as Topic; HIV Protease Inhibitors; Humans; Lung Neoplasms; Nelfinavir

2019
Nanotechnology Based Repositioning of an Anti-Viral Drug for Non-Small Cell Lung Cancer (NSCLC).
    Pharmaceutical research, 2020, Jun-08, Volume: 37, Issue:7

    Topics: Activating Transcription Factor 3; Anti-HIV Agents; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Drug Compounding; Drug Liberation; Drug Repositioning; Drug Stability; Gene Expression Regulation; HIV Protease Inhibitors; Humans; Lung Neoplasms; Microtubule-Associated Proteins; Nanocapsules; Nanotechnology; Nelfinavir; Polylactic Acid-Polyglycolic Acid Copolymer

2020
Nelfinavir Inhibits the Growth of Small-cell Lung Cancer Cells and Patient-derived Xenograft Tumors.
    Anticancer research, 2021, Volume: 41, Issue:1

    Topics: Animals; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Repositioning; Female; Humans; Lung Neoplasms; Mice; Nelfinavir; Small Cell Lung Carcinoma; TOR Serine-Threonine Kinases; Unfolded Protein Response; Xenograft Model Antitumor Assays

2021
Nelfinavir restricts A549 cell growth by inhibiting STAT3 signaling.
    The Journal of international medical research, 2021, Volume: 49, Issue:6

    Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Nelfinavir; STAT3 Transcription Factor

2021
Marked tumor response and fatal hemoptysis during radiation for lung cancer in a human immunodeficiency virus-positive patient taking nelfinavir.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2009, Volume: 4, Issue:12

    Topics: Carcinoma, Squamous Cell; Fatal Outcome; Hemoptysis; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; HIV-1; Humans; Lung Neoplasms; Male; Nelfinavir

2009
Nelfinavir down-regulates hypoxia-inducible factor 1alpha and VEGF expression and increases tumor oxygenation: implications for radiotherapy.
    Cancer research, 2006, Sep-15, Volume: 66, Issue:18

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Down-Regulation; Female; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Nelfinavir; Neovascularization, Pathologic; Oxygen; Protease Inhibitors; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Random Allocation; Sp1 Transcription Factor; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2006
NFV, an HIV-1 protease inhibitor, induces growth arrest, reduced Akt signalling, apoptosis and docetaxel sensitisation in NSCLC cell lines.
    British journal of cancer, 2006, Dec-18, Volume: 95, Issue:12

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Docetaxel; Down-Regulation; Drug Combinations; Glycogen Synthase Kinases; HIV Protease Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nelfinavir; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Signal Transduction; Taxoids; Tumor Suppressor Protein p53

2006