Page last updated: 2024-08-24

nelfinavir and Liposarcoma

nelfinavir has been researched along with Liposarcoma in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (33.33)	29.6817
2010's	2 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chow, WA; Fousek, K; Guan, M; Guo, S; Jiang, C; Shih, CC; Synold, T; Xi, B	1
Chow, WA; Fousek, K; Frankel, P; Guan, M; Hepner, E; Magnusson, R; Mott, M; Pan, J; Synold, T; Tinsley, R; Valdes, F; Xi, B	1
Chow, WA; Guo, S; Valdes-Albini, F	1

Trials

1 trial(s) available for nelfinavir and Liposarcoma

Article	Year
Phase I study of nelfinavir in liposarcoma. Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Drug Administration Schedule; Female; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Liposarcoma; Male; Middle Aged; Nelfinavir; Research Design; Treatment Outcome	2012

Other Studies

2 other study(ies) available for nelfinavir and Liposarcoma

Article	Year
Nelfinavir induces liposarcoma apoptosis through inhibition of regulated intramembrane proteolysis of SREBP-1 and ATF6. Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Apr-01, Volume: 17, Issue:7 Topics: Activating Transcription Factor 6; Animals; Antineoplastic Agents; Apoptosis; Caspase 6; Caspase 9; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Coumarins; Endoplasmic Reticulum; Enzyme Activation; Fatty Acid Synthase, Type I; Female; Humans; Isocoumarins; Liposarcoma; Metalloendopeptidases; Mice; Mice, SCID; Nelfinavir; Neoplasm Transplantation; Phenanthrolines; Proprotein Convertases; Protease Inhibitors; Protein Transport; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Serine Endopeptidases; Sterol Regulatory Element Binding Protein 1; Transcription, Genetic; Transplantation, Heterologous; Tumor Burden	2011
Nelfinavir induces liposarcoma apoptosis and cell cycle arrest by upregulating sterol regulatory element binding protein-1. Anti-cancer drugs, 2006, Volume: 17, Issue:8 Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; fas Receptor; HIV Protease Inhibitors; Humans; Liposarcoma; Nelfinavir; Sterol Regulatory Element Binding Protein 1; Tumor Suppressor Protein p53; Up-Regulation	2006

Article

Year

Nelfinavir induces liposarcoma apoptosis through inhibition of regulated intramembrane proteolysis of SREBP-1 and ATF6.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Apr-01, Volume: 17, Issue:7

Topics: Activating Transcription Factor 6; Animals; Antineoplastic Agents; Apoptosis; Caspase 6; Caspase 9; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Coumarins; Endoplasmic Reticulum; Enzyme Activation; Fatty Acid Synthase, Type I; Female; Humans; Isocoumarins; Liposarcoma; Metalloendopeptidases; Mice; Mice, SCID; Nelfinavir; Neoplasm Transplantation; Phenanthrolines; Proprotein Convertases; Protease Inhibitors; Protein Transport; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Serine Endopeptidases; Sterol Regulatory Element Binding Protein 1; Transcription, Genetic; Transplantation, Heterologous; Tumor Burden

2011

Nelfinavir induces liposarcoma apoptosis and cell cycle arrest by upregulating sterol regulatory element binding protein-1.

Anti-cancer drugs, 2006, Volume: 17, Issue:8

Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; fas Receptor; HIV Protease Inhibitors; Humans; Liposarcoma; Nelfinavir; Sterol Regulatory Element Binding Protein 1; Tumor Suppressor Protein p53; Up-Regulation

2006