Page last updated: 2024-08-24

nelfinavir and Disease Models, Animal

nelfinavir has been researched along with Disease Models, Animal in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's6 (54.55)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Connis, N; Dennis, PA; Gills, JJ; Hann, CL; Kawabata, S1
Cruz, JP; Machado, M; Mendes, AM; Prudêncio, M; Sanches-Vaz, M1
Fuselier, T; Gongora, R; Lasky, JA; MacKinnon, SS; Molinski, SV; Mondal, D; Sanchez, CG; Sosulski, M1
Carrillo, E; Mejías, F; Moreno, J; Sánchez, C; Valdivieso, E1
Al-Assar, O; Bittner, MI; Brunner, TB; Lunardi, S; McKenna, WG; Stratford, MR1
De Gassart, A; Demaria, O; Gilliet, M; Martinon, F; Panes, R; Ryazanov, AG; Zaffalon, L1
Bashan, N; Ben-Romano, R; Hou, JC; Kachko, I; Maissel, A; Mazor, L; Pessin, JE; Rudich, A; Watson, RT1
Algeciras-Schimnich, A; Badley, AD; Bren, GD; Chari, ST; Dawra, RK; Navina, S; Rizza, SA; Saluja, AK; Schnepple, D; Singh, VP; Vege, SS1
Andrews, S; Carlson, GA; Hanamsagar, R; Huang, Y; Ikezu, T; Kiyota, T; Lan, X; Peng, H; Swindells, S; Zheng, JC1
Badley, AD; Bennett, SA; Bren, GD; Brenner, C; Deniaud, A; Dong, L; Douen, A; Hardin, H; Hou, ST; Jiang, SX; Kroemer, G; Kroemer, RT; Lallier, J; Lebras, M; Lynch, DH; Moffat, TC; Morin, MY; Phenix, BN; Sim, VL; Tarze, A; van Heeswijk, RP; Weaver, JG; Wettstein, P; Zurakowski, B1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1

Other Studies

11 other study(ies) available for nelfinavir and Disease Models, Animal

ArticleYear
Nelfinavir Inhibits the Growth of Small-cell Lung Cancer Cells and Patient-derived Xenograft Tumors.
    Anticancer research, 2021, Volume: 41, Issue:1

    Topics: Animals; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Repositioning; Female; Humans; Lung Neoplasms; Mice; Nelfinavir; Small Cell Lung Carcinoma; TOR Serine-Threonine Kinases; Unfolded Protein Response; Xenograft Model Antitumor Assays

2021
Inhibition of
    Frontiers in cellular and infection microbiology, 2017, Volume: 7

    Topics: Alkynes; Animals; Anti-Retroviral Agents; Antimalarials; Benzoxazines; Cell Line; Cyclopropanes; Disease Models, Animal; Hepatocytes; Humans; Malaria; Male; Mice, Inbred C57BL; Nelfinavir; Nitriles; Plasmodium berghei; Pyridazines; Pyrimidines

2017
The Antiretroviral Agent Nelfinavir Mesylate: A Potential Therapy for Systemic Sclerosis.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:1

    Topics: Animals; Anti-Retroviral Agents; Cell Culture Techniques; Cell Differentiation; Computer Simulation; Disease Models, Animal; Fibroblasts; Humans; Lung; Male; Mice; Mice, Inbred C57BL; Nelfinavir; Pulmonary Fibrosis; Scleroderma, Systemic; Signal Transduction; Skin; Transforming Growth Factor beta1

2018
Potentiation of the leishmanicidal activity of nelfinavir in combination with miltefosine or amphotericin B.
    International journal of antimicrobial agents, 2018, Volume: 52, Issue:5

    Topics: Amphotericin B; Animals; Antiprotozoal Agents; Cell Survival; Disease Models, Animal; Drug Synergism; Humans; Leishmania infantum; Leishmaniasis, Visceral; Liver; Male; Mice, Inbred BALB C; Nelfinavir; Parasite Load; Phosphorylcholine; Spleen; Treatment Outcome

2018
The radiosensitizing effects of Nelfinavir on pancreatic cancer with and without pancreatic stellate cells.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2016, Volume: 119, Issue:2

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; HIV Protease Inhibitors; Mice; Mice, Nude; Nelfinavir; Pancreatic Neoplasms; Pancreatic Stellate Cells; Radiation-Sensitizing Agents

2016
Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.
    EMBO reports, 2016, Volume: 17, Issue:10

    Topics: AMP-Activated Protein Kinases; Animals; Cell Death; Cell Line; Cell Survival; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance; Elongation Factor 2 Kinase; Female; Gene Expression; Humans; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Knockout; Multiprotein Complexes; Nelfinavir; Neoplasms; Peptide Elongation Factor 2; Phosphorylation; Protein Biosynthesis; TOR Serine-Threonine Kinases; Tumor Burden

2016
Postreceptoral adipocyte insulin resistance induced by nelfinavir is caused by insensitivity of PKB/Akt to phosphatidylinositol-3,4,5-trisphosphate.
    Endocrinology, 2009, Volume: 150, Issue:6

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Membrane; Disease Models, Animal; Glucose; Glucose Transporter Type 4; Green Fluorescent Proteins; HIV Protease Inhibitors; Insulin; Insulin Resistance; Mice; Nelfinavir; Phosphatidylinositol Phosphates; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Signal Transduction

2009
Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:5

    Topics: Amylases; Animals; Apoptosis; Caspase 3; Ceruletide; Cytochromes c; Disease Models, Animal; Drug Therapy, Combination; HIV Protease Inhibitors; Inflammation Mediators; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Necrosis; Nelfinavir; Pancreas; Pancreatitis; Ritonavir; Trypsin

2009
The effect of HIV protease inhibitors on amyloid-β peptide degradation and synthesis in human cells and Alzheimer's disease animal model.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2012, Volume: 7, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Atazanavir Sulfate; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; HIV Protease Inhibitors; Humans; Immunoblotting; Immunohistochemistry; Lopinavir; Macrophages; Mice; Mice, SCID; Mice, Transgenic; Nelfinavir; Neurons; Oligopeptides; Pyridines; Ritonavir; Saquinavir

2012
Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor.
    The Journal of clinical investigation, 2005, Volume: 115, Issue:7

    Topics: Animals; Antibodies; Apoptosis; Disease Models, Animal; Female; Hepatitis; HIV Protease Inhibitors; Humans; Jurkat Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitochondrial ADP, ATP Translocases; Models, Molecular; Nelfinavir; Ritonavir; Shock, Septic; Signal Transduction; Stroke

2005
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020