Page last updated: 2024-08-24

nelfinavir and Diarrhea

nelfinavir has been researched along with Diarrhea in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (29.41)18.2507
2000's12 (70.59)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Black, FT; Jensen-Fangel, S; Justesen, US; Obel, N; Pedersen, C1
Alper, SL; Andrade, A; Flexner, C; Jiang, L; Lencer, WI; Lin, PW; Rameh, L; Rufo, PA1
DeSilva, KE; Guest, JL; Rimland, D; Ruffin, C; Tschampa, JM1
Arasteh, K; Artigas, JG; Clotet, B; Danise, A; Foreman, R; Gonzalez-Garcia, J; Horban, A; Johnson, M; Landman, R; Nieto-Cisneros, L; Proll, S; Smith, P; Snowden, W1
Garner, RC; Hsyu, PH; Lappin, G; Sarapa, N1
Crownover, PH; Damle, BD; Fang, AF; Glue, PW; Hewlett, D; LaBadie, RR1
Hart, AA; Hoetelmans, RM; Lange, JM; Mulder, JW; Reijers, MH; Reiss, P; Schuitemaker, H; Ten Kate, RW; Weigel, HM; Weverling, GJ1
Ryan, A1
Bode, H; Fromm, M; Riecken, EO; Schmidt, W; Schulzke, JD; Ullrich, R1
Fornataro, K; Jefferys, R1
Baede-van Dijk, PA; Burger, DM; Hekster, YA; Hugen, PW; Koopmans, PP; Verweij-van Wissen, CP1
Gartland, M1

Trials

7 trial(s) available for nelfinavir and Diarrhea

ArticleYear
The use of calcium carbonate in nelfinavir-associated diarrhoea in HIV-1-infected patients.
    HIV medicine, 2003, Volume: 4, Issue:1

    Topics: Adult; Aged; Antiretroviral Therapy, Highly Active; Calcium Carbonate; Calcium Gluconate; Chronic Disease; Diarrhea; Drug Combinations; Drug Interactions; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Middle Aged; Nelfinavir; Pilot Projects; Prospective Studies; Severity of Illness Index

2003
Comparison of gastrointestinal tolerability and patient preference for treatment with the 625 mg and 250 mg nelfinavir tablet formulations.
    HIV medicine, 2005, Volume: 6, Issue:2

    Topics: CD4 Lymphocyte Count; Diarrhea; Drug Administration Schedule; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Nelfinavir; Patient Satisfaction; Tablets; Viral Load

2005
The application of accelerator mass spectrometry to absolute bioavailability studies in humans: simultaneous administration of an intravenous microdose of 14C-nelfinavir mesylate solution and oral nelfinavir to healthy volunteers.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:10

    Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Biological Availability; Carbon Radioisotopes; Diarrhea; HIV Protease Inhibitors; Humans; Infusions, Intravenous; Male; Mass Spectrometry; Metabolic Clearance Rate; Middle Aged; Nelfinavir; Reproducibility of Results; Time Factors

2005
Significant decrease in nelfinavir systemic exposure after omeprazole coadministration in healthy subjects.
    Pharmacotherapy, 2008, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diarrhea; Dizziness; Drug Interactions; Female; Gastric Juice; Headache; HIV Protease Inhibitors; Humans; Hydrogen-Ion Concentration; Male; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Nelfinavir; Omeprazole; Proton Pump Inhibitors; Syncope; Tablets

2008
Toxicity and drug exposure in a quadruple drug regimen in HIV-1 infected patients participating in the ADAM study.
    AIDS (London, England), 2000, Jan-07, Volume: 14, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Diarrhea; Drug Therapy, Combination; Female; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Liver; Male; Middle Aged; Nausea; Nelfinavir; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine

2000
Analysis of variation in plasma concentrations of nelfinavir and its active metabolite M8 in HIV-positive patients.
    AIDS (London, England), 2001, May-25, Volume: 15, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Aryl Hydrocarbon Hydroxylases; Body Weight; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Databases, Factual; Diarrhea; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Induction; Enzyme Inhibitors; Female; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; Humans; Male; Middle Aged; Mixed Function Oxygenases; Nelfinavir; Omeprazole

2001
AVANTI 3: a randomized, double-blind trial to compare the efficacy and safety of lamivudine plus zidovudine versus lamivudine plus zidovudine plus nelfinavir in HIV-1-infected antiretroviral-naive patients.
    Antiviral therapy, 2001, Volume: 6, Issue:2

    Topics: Administration, Oral; Adult; Anti-HIV Agents; Clinical Protocols; Diarrhea; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nausea; Nelfinavir; Patient Compliance; RNA, Viral; Zidovudine

2001

Other Studies

10 other study(ies) available for nelfinavir and Diarrhea

ArticleYear
Supplement fix for nelfinavir-related diarrhea.
    TreatmentUpdate, 2002, Volume: 14, Issue:8

    Topics: Diarrhea; Dietary Fiber; HIV Infections; HIV Protease Inhibitors; Humans; Nelfinavir; Probiotics

2002
Diarrhea-associated HIV-1 APIs potentiate muscarinic activation of Cl- secretion by T84 cells via prolongation of cytosolic Ca2+ signaling.
    American journal of physiology. Cell physiology, 2004, Volume: 286, Issue:5

    Topics: Adult; Aspartic Acid Endopeptidases; Calcium Signaling; Carbachol; Cell Line; Cell Membrane; Chlorides; Cytosol; Diarrhea; Drug Synergism; Electric Conductivity; HIV Infections; HIV-1; Humans; Intestinal Mucosa; Intracellular Membranes; Middle Aged; Muscarinic Agonists; Nelfinavir; Protease Inhibitors; Time Factors

2004
Differences in rates of diarrhea in patients with human immunodeficiency virus receiving lopinavir-ritonavir or nelfinavir.
    Pharmacotherapy, 2004, Volume: 24, Issue:6

    Topics: Adult; Anti-Retroviral Agents; Antidiarrheals; Antiretroviral Therapy, Highly Active; Cohort Studies; Diarrhea; Georgia; HIV Infections; Humans; Incidence; Lopinavir; Middle Aged; Nelfinavir; Pyrimidinones; Retrospective Studies; Ritonavir; United States; United States Department of Veterans Affairs

2004
Drugs for HIV infection.
    The Medical letter on drugs and therapeutics, 1997, Dec-12, Volume: 39, Issue:1015

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Delavirdine; Diarrhea; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Virus Replication; Zalcitabine; Zidovudine

1997
Calcium may help with diarrhea.
    AIDS patient care and STDs, 1999, Volume: 13, Issue:12

    Topics: Calcium; Diarrhea; HIV Protease Inhibitors; Humans; Nelfinavir; Severity of Illness Index; Treatment Outcome

1999
Pancrelipase for treatment-refractory diarrhea associated with nelfinavir.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2000, Jun-15, Volume: 57, Issue:12

    Topics: Adult; Diarrhea; Gastrointestinal Agents; HIV Protease Inhibitors; Humans; Male; Nelfinavir; Pancrelipase; Treatment Outcome

2000
Effects of HIV protease inhibitors on barrier function in the human intestinal cell line HT-29/B6.
    Annals of the New York Academy of Sciences, 2000, Volume: 915

    Topics: Acquired Immunodeficiency Syndrome; Colon; Diarrhea; HIV Protease Inhibitors; HT29 Cells; Humans; Indinavir; Intestinal Absorption; Intestinal Mucosa; Nelfinavir; Ritonavir; Saquinavir

2000
New drug approved to treat HIV.
    Treatment review, 1997, Issue:No 24

    Topics: Acquired Immunodeficiency Syndrome; Adult; CD4 Lymphocyte Count; Child; Clinical Trials as Topic; Diarrhea; Drug Approval; Drug Interactions; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Nelfinavir; Sulfonic Acids; United States; United States Food and Drug Administration; Viral Load

1997
Ultrase and Viracept.
    The Body positive, 1999, Volume: 12, Issue:10

    Topics: Clinical Trials as Topic; Diarrhea; Drug Interactions; Enzyme Therapy; HIV Infections; HIV Protease Inhibitors; Humans; Nelfinavir; New York City; Pancreas; Washington

1999
Twice-daily dosing of Nelfinavir approved.
    Research initiative, treatment action : RITA, 1999, Volume: 5, Issue:5

    Topics: Diarrhea; HIV Infections; HIV Protease Inhibitors; Humans; Nelfinavir

1999