Compounds > nelfinavir
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nelfinavir and Chemical and Drug Induced Liver Injury

nelfinavir has been researched along with Chemical and Drug Induced Liver Injury in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's8 (61.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Battista, C; Howell, BA; Mettetal, JT; Siler, SQ; Stahl, SH; Watkins, PB; Woodhead, JL; Yang, K1
Akoth, B; Angira, F; Masaba, R; Mills, LA; Minniear, TD; Ndivo, R; Oyaro, B; Peters, PJ; Polle, N; Thomas, TK; Zeh, C1
Boer, K; de Wolf, F; Dieleman, J; Godfried, MH; Nellen, J; Schneider, ME; Sprenger, H; Tempelman, C; Timmermans, S; van der Ende, ME1
Bruno, R; Filice, G; Maiocchi, L; Sacchi, P; Zocchetti, C1
Arizcorreta-Yarza, A; Becker, MI; Caballero-Granado, FJ; Girón-González, JA; Gómez-Mateos, J; González-Serrano, M; Jiménez-Mejías, ME; Macías, J; Merino, D; Mira, JA; Pineda, JA; Terrón, A; Torre-Cisneros, J1
Barnosky, S; Trapé, M1

Reviews

2 review(s) available for nelfinavir and Chemical and Drug Induced Liver Injury

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Hepatotoxicity and nelfinavir: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:5

    Topics: Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Liver; Nelfinavir

2005

Other Studies

11 other study(ies) available for nelfinavir and Chemical and Drug Induced Liver Injury

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters.
    Clinical pharmacology and therapeutics, 2017, Volume: 101, Issue:4

    Topics: Animals; Bilirubin; Carrier Proteins; Chemical and Drug Induced Liver Injury; Computer Simulation; Enzyme Inhibitors; HIV Protease Inhibitors; Humans; Hyperbilirubinemia; Indinavir; Liver; Mice; Mice, Knockout; Models, Biological; Nelfinavir; Pharmacokinetics; Rats; Rats, Gunn; Receptors, Chemokine; Systems Biology

2017
Rash, hepatotoxicity and hyperbilirubinemia among Kenyan infants born to HIV-infected women receiving triple-antiretroviral drugs for the prevention of mother-to-child HIV transmission.
    The Pediatric infectious disease journal, 2012, Volume: 31, Issue:11

    Topics: Adult; Aging, Premature; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; HIV Infections; Humans; Hyperbilirubinemia; Infant, Newborn; Infectious Disease Transmission, Vertical; Kenya; Nelfinavir; Nevirapine; Pregnancy

2012
[HAART and pregnancy. Nelfinavir superiority in hepatotoxicity].
    MMW Fortschritte der Medizin, 2004, Apr-26, Volume: 146 Spec No 1

    Topics: Abnormalities, Drug-Induced; Animals; Antiretroviral Therapy, Highly Active; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Female; HIV Infections; Humans; Infant, Newborn; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Risk Assessment

2004
Nelfinavir and nevirapine side effects during pregnancy.
    AIDS (London, England), 2005, May-20, Volume: 19, Issue:8

    Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Female; HIV Infections; HIV Protease Inhibitors; Humans; Hyperglycemia; Nausea; Nelfinavir; Netherlands; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors

2005
Incidence of and risk factors for severe hepatotoxicity of nelfinavir-containing regimens among HIV-infected patients with chronic hepatitis C.
    The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:1

    Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Therapy, Combination; Female; Hepatitis C, Chronic; HIV Infections; Humans; Incidence; Male; Nelfinavir; Retrospective Studies; Risk Factors

2006
Nelfinavir in expanded postexposure prophylaxis causing acute hepatitis with cholestatic features: two case reports.
    Infection control and hospital epidemiology, 2001, Volume: 22, Issue:6

    Topics: Adult; Chemical and Drug Induced Liver Injury; Chemoprevention; Cholestasis; HIV Infections; HIV Protease Inhibitors; Humans; Male; Middle Aged; Nelfinavir

2001