Compounds > nelfinavir
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nelfinavir and Cancer of Ovary

nelfinavir has been researched along with Cancer of Ovary in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Andrade, MF; Bowers, RR; Delaney, JR; Jones, CM; Voelkel-Johnson, C; White-Gilbertson, S1
Brüning, A; Burger, P; Burges, A; Friese, K; Gingelmaier, A; Lenhard, M; Rahmeh, M; Vogel, M1
Brüning, A; Burger, P; Burges, A; Friese, K; Gingelmaiers, A; Lenhard, M; Rahmeh, M; Vogel, M1
Salahub, DR; Wu, W; Zhang, R1
Brüning, A; Burger, P; Burges, A; Friese, K; Gingelmaier, A; Vogel, M1

Other Studies

5 other study(ies) available for nelfinavir and Cancer of Ovary

ArticleYear
Autophagy modulating therapeutics inhibit ovarian cancer colony generation by polyploid giant cancer cells (PGCCs).
    BMC cancer, 2022, Apr-14, Volume: 22, Issue:1

    Topics: Apoptosis; Autophagy; Carboplatin; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Docetaxel; Female; Giant Cells; Humans; Hydroxychloroquine; Nelfinavir; Ovarian Neoplasms; Polyploidy; Sirolimus

2022
Nelfinavir induces TRAIL receptor upregulation in ovarian cancer cells.
    Biochemical and biophysical research communications, 2008, Dec-26, Volume: 377, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Female; HIV Protease Inhibitors; Humans; Nelfinavir; Ovarian Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; Up-Regulation

2008
Nelfinavir induces the unfolded protein response in ovarian cancer cells, resulting in ER vacuolization, cell cycle retardation and apoptosis.
    Cancer biology & therapy, 2009, Volume: 8, Issue:3

    Topics: Apoptosis; Cell Culture Techniques; Cell Cycle; Cell Line, Tumor; Cyclin D3; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Eukaryotic Initiation Factor-2; Female; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; HIV Protease Inhibitors; Humans; Nelfinavir; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Phosphorylation; Protein Folding; Vacuoles

2009
Nelfinavir: a magic bullet to annihilate cancer cells?
    Cancer biology & therapy, 2009, Volume: 8, Issue:3

    Topics: Animals; Drug Resistance, Neoplasm; Female; HIV Protease Inhibitors; Humans; Nelfinavir; Off-Label Use; Ovarian Neoplasms

2009
Nelfinavir induces mitochondria protection by ERK1/2-mediated mcl-1 stabilization that can be overcome by sorafenib.
    Investigational new drugs, 2010, Volume: 28, Issue:5

    Topics: Annexin A5; Antineoplastic Agents; Benzenesulfonates; Cell Death; Cell Line, Tumor; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Female; HIV Protease Inhibitors; Humans; Membrane Potential, Mitochondrial; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Nelfinavir; Niacinamide; Ovarian Neoplasms; Phenylurea Compounds; Phosphorylation; Propidium; Protein Stability; Proto-Oncogene Proteins c-bcl-2; Pyridines; Sorafenib

2010