Page last updated: 2024-08-24

nelfinavir and Cancer of Cervix

nelfinavir has been researched along with Cancer of Cervix in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Charnalia, M; Chopra, S; Deodhar, K; Engineer, R; Ghosh, J; Goda, JS; Gota, V; Gulia, S; Gupta, S; Kannan, S; Krishnamurthy, MN; Mahantshetty, U; Menon, S; Mittal, P; Mulani, J; Naidu, L; Pai, V; Pant, S; Popat, P; Rangarajan, V; Rath, S; Sawant, S; Shah, S; Thakkar, P1
Garcia-Soto, AE; Hu, JJ; Jimenez, EA; Kossenkov, A; Lin, LL; Lucci, JA; Maity, A; McKenzie, ND; Mills, GB; Pearson, JM; Portelance, L; Qureshi, R; Schwartz, L; Simpkins, F; Whicker, ME1
Chen, R; He, Z; Jiang, S; Liang, S; Xia, C; Xiao, G; Xu, W; Yang, J1
Du, L; Jiang, S; Pham, P; Xiang, T; Zhu, B1
Davis, MA; Delaney, JR; Patel, CB; Storgard, R; Stupack, DG1
Chen, J; Chen, R; Du, L; Jiang, S; Pan, Y; Qi, Q; Xia, C; Xiao, G1
Bruning, A; Burges, A; Friese, K; Mylonas, I; Vogel, M1

Trials

2 trial(s) available for nelfinavir and Cancer of Cervix

ArticleYear
Concurrent chemoradiation and brachytherapy alone or in combination with nelfinavir in locally advanced cervical cancer (NELCER): study protocol for a phase III trial.
    BMJ open, 2022, 04-06, Volume: 12, Issue:4

    Topics: Adult; Brachytherapy; Clinical Trials, Phase III as Topic; Female; Humans; Middle Aged; Nelfinavir; Neoplasm Recurrence, Local; Proto-Oncogene Proteins c-akt; Quality of Life; Uterine Cervical Neoplasms

2022
Phase 1 trial of nelfinavir added to standard cisplatin chemotherapy with concurrent pelvic radiation for locally advanced cervical cancer.
    Cancer, 2021, 07-01, Volume: 127, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Female; Humans; Nelfinavir; Uterine Cervical Neoplasms

2021

Other Studies

5 other study(ies) available for nelfinavir and Cancer of Cervix

ArticleYear
Metformin combined with nelfinavir induces SIRT3/mROS-dependent autophagy in human cervical cancer cells and xenograft in nude mice.
    European journal of pharmacology, 2019, Apr-05, Volume: 848

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Female; HeLa Cells; HIV Protease Inhibitors; Humans; Hypoglycemic Agents; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; Nelfinavir; Reactive Oxygen Species; Sirtuin 3; Tumor Burden; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2019
Nelfinavir, an HIV protease inhibitor, induces apoptosis and cell cycle arrest in human cervical cancer cells via the ROS-dependent mitochondrial pathway.
    Cancer letters, 2015, Aug-01, Volume: 364, Issue:1

    Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Female; HIV Protease Inhibitors; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Nelfinavir; Reactive Oxygen Species; Uterine Cervical Neoplasms

2015
Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Antineoplastic Agents; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Female; Humans; Nelfinavir; Uterine Cervical Neoplasms

2016
Combining metformin and nelfinavir exhibits synergistic effects against the growth of human cervical cancer cells and xenograft in nude mice.
    Scientific reports, 2017, 03-02, Volume: 7

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Synergism; Female; Heterografts; Humans; Metformin; Mice, Nude; Nelfinavir; Neoplasm Transplantation; Treatment Outcome; Uterine Cervical Neoplasms

2017
Bortezomib targets the caspase-like proteasome activity in cervical cancer cells, triggering apoptosis that can be enhanced by nelfinavir.
    Current cancer drug targets, 2011, Volume: 11, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Caspases; Cell Cycle; Drug Synergism; Female; HIV Protease Inhibitors; Humans; Membrane Potential, Mitochondrial; Nelfinavir; Proteasome Inhibitors; Pyrazines; Receptors, TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2011