Page last updated: 2024-08-24

nelfinavir and Breast Cancer

nelfinavir has been researched along with Breast Cancer in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's7 (63.64)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Gupta, A; Mao, Q; Unadkat, JD; Zhang, Y1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Andrews, DW; Ba-Alawi, W; Branchard, E; Cescon, DW; Cruickshank, J; Gendoo, DMA; Gross, PL; Haibe-Kains, B; Longo, J; Penn, LZ; Schormann, W; Silvester, J; van Leeuwen, JE1
Garcia-Orad, A; Gutierrez-Camino, A; Lopez-Lopez, E; Martin-Guerrero, I1
Kapoor, S1
Abdel-Mageed, AB; Chakravarty, G; Datta, A; Gerlach, S; Mallade, P; Mathur, A; Mondal, D; Srivastav, S; Willis, J1
Bianco, R; Campiglia, P; D'Alessio, M; D'Angelo, D; Forestieri, P; Formisano, P; Iaccarino, G; Illario, M; Limite, G; Maione, AS; Rusciano, MR; Soprano, M; Sorriento, D1
Chen, TC; Cho, HY; Gaffney, KJ; Golden, EB; Hofman, FM; Louie, SG; Petasis, NA; Schönthal, AH; Thomas, S1
Brüning, A; Burges, A; Friese, K; Mylonas, I1
Agarwal, P; Chen, TC; Cho, H; Gaffney, KJ; Golden, EB; Hofman, FM; Louie, SG; Petasis, NA; Schönthal, AH; Sharma, N; Thomas, S1
Beebe, K; Han, I; Liu, JO; Nahta, R; Neckers, L; Rao, R; Shim, JS1

Reviews

1 review(s) available for nelfinavir and Breast Cancer

ArticleYear
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022

Other Studies

10 other study(ies) available for nelfinavir and Breast Cancer

ArticleYear
HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2).
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:1

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Breast Neoplasms; Cells, Cultured; Drug Resistance, Neoplasm; Gene Expression; HIV Protease Inhibitors; Humans; Indinavir; Mitoxantrone; Nelfinavir; Neoplasm Proteins; Ritonavir; Saquinavir; Tritium

2004
Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins.
    Nature communications, 2022, 10-24, Volume: 13, Issue:1

    Topics: Breast Neoplasms; Cadherins; Cholesterol; Clotrimazole; Dipyridamole; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Nelfinavir; Pharmacogenetics; Vemurafenib

2022
Re: novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.
    Journal of the National Cancer Institute, 2013, Oct-02, Volume: 105, Issue:19

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Female; HIV Protease Inhibitors; HSP90 Heat-Shock Proteins; Humans; Nelfinavir; Receptor, ErbB-2

2013
Re: selective inhibition of Her2-positive breast cancer cells by the HIV protease inhibitor nelfinavir.
    Journal of the National Cancer Institute, 2013, Oct-02, Volume: 105, Issue:19

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Female; HIV Protease Inhibitors; HSP90 Heat-Shock Proteins; Humans; Nelfinavir; Receptor, ErbB-2

2013
Nelfinavir targets multiple drug resistance mechanisms to increase the efficacy of doxorubicin in MCF-7/Dox breast cancer cells.
    Biochimie, 2016, Volume: 124

    Topics: Animals; Breast Neoplasms; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nelfinavir; Xenograft Model Antitumor Assays

2016
Oxidative Stress Mediates the Antiproliferative Effects of Nelfinavir in Breast Cancer Cells.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Female; HIV Protease Inhibitors; Humans; Nelfinavir; Oxidative Stress; Reactive Oxygen Species; Tumor Cells, Cultured

2016
Enhanced killing of chemo-resistant breast cancer cells via controlled aggravation of ER stress.
    Cancer letters, 2009, Sep-08, Volume: 282, Issue:1

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Colony-Forming Units Assay; DNA, Neoplasm; Doxorubicin; Endoplasmic Reticulum; Enzyme-Linked Immunosorbent Assay; Female; HIV Protease Inhibitors; Humans; Nelfinavir; Pyrazoles; Sulfonamides

2009
Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells.
    Breast cancer research : BCR, 2010, Volume: 12, Issue:4

    Topics: Activating Transcription Factor 3; Antineoplastic Agents, Hormonal; Apoptosis; Autophagy; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Female; Glutathione; HIV Protease Inhibitors; Humans; Nelfinavir; Poly(ADP-ribose) Polymerases; Tamoxifen; Time Factors

2010
Preferential killing of triple-negative breast cancer cells in vitro and in vivo when pharmacological aggravators of endoplasmic reticulum stress are combined with autophagy inhibitors.
    Cancer letters, 2012, Dec-01, Volume: 325, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Breast Neoplasms; Celecoxib; Cell Line, Tumor; Chloroquine; Endoplasmic Reticulum Stress; Female; Humans; MCF-7 Cells; Mice; Mice, Nude; Nelfinavir; Pyrazoles; Sulfonamides; Xenograft Model Antitumor Assays

2012
Selective inhibition of HER2-positive breast cancer cells by the HIV protease inhibitor nelfinavir.
    Journal of the National Cancer Institute, 2012, Oct-17, Volume: 104, Issue:20

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Female; Fluorescent Antibody Technique; HIV Protease Inhibitors; HSP90 Heat-Shock Proteins; Humans; Immunoblotting; Immunoprecipitation; Mice; Mice, Nude; Middle Aged; Nelfinavir; Protein Conformation; Receptor, ErbB-2; Regression Analysis; Signal Transduction; Transplantation, Heterologous

2012