Page last updated: 2024-08-24

nelfinavir and Body Weight

nelfinavir has been researched along with Body Weight in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's10 (83.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eichinger-Chapelon, A; Pfister, T1
Aguiar, CV; Braga Neto, MB; Brito, GA; Guerrant, RL; Lima, AA; Maciel, JG; Oliveira, BM; Oriá, RB; Sevilleja, JE; Warren, CA1
Bergshoeff, AS; Burger, DM; de Groot, R; Fraaij, PL; Geelen, SP; van Rossum, AM; Wolfs, TF1
Aweeka, FT; Floren, LC; Hayashi, S; Jayewardene, A; Johnson, G; Krogstad, P; Nachman, S; Stanley, K; Wiznia, A1
Doyle, ME; Ellis, KJ; Hardin, DS; Rice, J1
Bressolle, F; Compagnucci, A; Faye, A; Giaquinto, C; Gibbs, D; Gomeni, R; Jacqz-Aigrain, E; Payen, S1
Alvero, C; Fenton, T; Fletcher, CV; Saitoh, A; Spector, SA1
Auleley, S; Duval, X; Hirt, D; Mentré, F; Rey, E; Salmon, D; Tran, A; Tréluyer, JM1
Elmadfa, I; Jilma, B; Parschalk, B; Pernerstorfer-Schoen, H; Schindl, A; Schindler, K; Thoeny-Lampert, S; Tschachler, E; Wunderer, K1
Elmadfa, I; Pernerstorfer-Schoen, H; Rieger, A; Schindler, K; Schneider, B1
Croom, DK; Furfine, ES; Lenhard, JM; Reynolds, DJ; Spaltenstein, A; Weiel, JE1
Baede-van Dijk, PA; Burger, DM; Hekster, YA; Hugen, PW; Koopmans, PP; Verweij-van Wissen, CP1

Trials

4 trial(s) available for nelfinavir and Body Weight

ArticleYear
Nelfinavir pharmacokinetics in stable human immunodeficiency virus-positive children: Pediatric AIDS Clinical Trials Group Protocol 377.
    Pediatrics, 2003, Volume: 112, Issue:3 Pt 1

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Antiretroviral Therapy, Highly Active; Biological Availability; Body Weight; Child; Child, Preschool; Dosage Forms; Drug Administration Schedule; HIV Protease Inhibitors; HIV-1; Humans; Infant; Nelfinavir; Nevirapine

2003
Bayesian parameter estimates of nelfinavir and its active metabolite, hydroxy-tert-butylamide, in infants perinatally infected with human immunodeficiency virus type 1.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:2

    Topics: Aging; Bayes Theorem; Body Weight; Chromatography, High Pressure Liquid; Didanosine; Drug Interactions; Half-Life; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infant; Infant, Newborn; Models, Biological; Nelfinavir; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization; Stavudine

2005
Positive impact of protease inhibitors on body composition and energy expenditure in HIV-infected and AIDS patients.
    Annals of the New York Academy of Sciences, 2000, Volume: 904

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Body Composition; Body Weight; Diet; Drug Therapy, Combination; Energy Intake; Energy Metabolism; Follow-Up Studies; HIV Protease Inhibitors; HIV Seropositivity; Humans; Nelfinavir; Weight Gain

2000
Analysis of variation in plasma concentrations of nelfinavir and its active metabolite M8 in HIV-positive patients.
    AIDS (London, England), 2001, May-25, Volume: 15, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Aryl Hydrocarbon Hydroxylases; Body Weight; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Databases, Factual; Diarrhea; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Induction; Enzyme Inhibitors; Female; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; Humans; Male; Middle Aged; Mixed Function Oxygenases; Nelfinavir; Omeprazole

2001

Other Studies

8 other study(ies) available for nelfinavir and Body Weight

ArticleYear
General 4-week toxicity study with EMS in the rat.
    Toxicology letters, 2009, Nov-12, Volume: 190, Issue:3

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Drug Contamination; Eating; Ethyl Methanesulfonate; Female; Genitalia; Hematologic Tests; Hemoglobins; HIV Protease Inhibitors; Male; Mutagens; Nelfinavir; Organ Size; Rats; Rats, Wistar; Risk Assessment; Specific Pathogen-Free Organisms; Toxicity Tests

2009
Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation, necrosis, apoptosis in intestinal epithelial cells and electrolyte and water transport and epithelial barrier function in mice.
    BMC gastroenterology, 2010, Aug-11, Volume: 10

    Topics: Animals; Anti-Retroviral Agents; Apoptosis; Body Weight; Cell Membrane Permeability; Cell Proliferation; Didanosine; HIV Protease Inhibitors; Indinavir; Intestinal Absorption; Intestinal Mucosa; Male; Mice; Models, Animal; Necrosis; Nelfinavir; Reverse Transcriptase Inhibitors; Survival Rate; Water-Electrolyte Balance; Zidovudine

2010
Pharmacokinetics of nelfinavir in children: influencing factors and dose implications.
    Antiviral therapy, 2003, Volume: 8, Issue:3

    Topics: Adolescent; Body Surface Area; Body Weight; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Male; Nelfinavir; Retrospective Studies; RNA, Viral

2003
Protease inhibitor therapy improves protein catabolism in prepubertal children with HIV infection.
    Journal of pediatric endocrinology & metabolism : JPEM, 2004, Volume: 17, Issue:3

    Topics: Body Composition; Body Weight; Carbon Isotopes; CD4 Lymphocyte Count; Child; Child, Preschool; Clinical Trials as Topic; Drug Administration Schedule; Energy Metabolism; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infusions, Intravenous; Leucine; Male; Muscle Proteins; Nelfinavir; Time Factors; Viral Load

2004
Impact of nucleoside reverse transcriptase inhibitors on mitochondria in human immunodeficiency virus type 1-infected children receiving highly active antiretroviral therapy.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Adolescent; Age Factors; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Body Mass Index; Body Weight; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; DNA, Mitochondrial; DNA, Viral; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Lipids; Longitudinal Studies; Mitochondria; Nelfinavir; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA, Viral

2007
Effect of CYP2C19 polymorphism on nelfinavir to M8 biotransformation in HIV patients.
    British journal of clinical pharmacology, 2008, Volume: 65, Issue:4

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Biotransformation; Body Weight; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Female; Genotype; HIV Infections; HIV Protease Inhibitors; Humans; Male; Middle Aged; Mixed Function Oxygenases; Nelfinavir; Polymorphism, Genetic; Treatment Outcome; Viral Load

2008
Beneficial effects of protease inhibitors on body composition and energy expenditure: a comparison between HIV-infected and AIDS patients.
    AIDS (London, England), 1999, Dec-03, Volume: 13, Issue:17

    Topics: Acquired Immunodeficiency Syndrome; Adult; Basal Metabolism; Body Composition; Body Weight; Case-Control Studies; Cohort Studies; Didanosine; Energy Metabolism; Female; HIV Infections; HIV Protease Inhibitors; Humans; Longitudinal Studies; Male; Middle Aged; Nelfinavir; Prospective Studies; Stavudine; Viremia

1999
Dietary fat alters HIV protease inhibitor-induced metabolic changes in mice.
    The Journal of nutrition, 2000, Volume: 130, Issue:9

    Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Carbamates; Dietary Fats; Drug Interactions; Furans; HIV Protease Inhibitors; Indinavir; Injections, Subcutaneous; Insulin; Liver; Male; Mice; Mice, Inbred AKR; Nelfinavir; Saquinavir; Sulfonamides

2000