nelfinavir has been researched along with Astrocytoma, Grade IV in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boockvar, JA; Brüning, A; Cappello, F; Chang, WW; Cvek, B; Dou, QP; Duenas-Gonzalez, A; Efferth, T; Focosi, D; Ghaffari, SH; Halatsch, ME; Karpel-Massler, G; Kast, RE; Keizman, D; Ketola, K; Khoshnevisan, A; Magné, N; Marosi, C; McDonald, K; Muñoz, M; Paranjpe, A; Pourgholami, MH; Sardi, I; Sella, A; Srivenugopal, KS; Tuccori, M; Wang, W; Wirtz, CR | 1 |
| Alonso-Basanta, M; Dorsey, JF; Fang, P; Hahn, SM; Lustig, RA; Maity, A | 1 |
| Alonso-Basanta, M; Dorsey, JF; Hahn, SM; Koumenis, C; Tian, X; Ye, J | 1 |
| Halatsch, ME; Kast, RE | 1 |
| Cerniglia, GJ; Gupta, AK; Maity, A; Pore, N | 1 |
| Bernhard, EJ; Cerniglia, GJ; Georgescu, MM; Gupta, AK; Hahn, SM; Jiang, Z; Maity, A; Mick, R; Pore, N | 1 |
2 review(s) available for nelfinavir and Astrocytoma, Grade IV
| Article | Year |
|---|---|
A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Artemisinins; Auranofin; Brain Neoplasms; Captopril; Dacarbazine; Disulfiram; Glioblastoma; Gluconates; Humans; Ketoconazole; Morpholines; Nelfinavir; Neoplasm Recurrence, Local; Sertraline; Succinates; Temozolomide | 2013 |
Matrix metalloproteinase-2 and -9 in glioblastoma: a trio of old drugs-captopril, disulfiram and nelfinavir-are inhibitors with potential as adjunctive treatments in glioblastoma.
Topics: Angiotensin-Converting Enzyme Inhibitors; Brain Neoplasms; Captopril; Chemotherapy, Adjuvant; Disulfiram; Glioblastoma; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Nelfinavir | 2012 |
1 trial(s) available for nelfinavir and Astrocytoma, Grade IV
| Article | Year |
|---|---|
A phase I study of nelfinavir concurrent with temozolomide and radiotherapy in patients with glioblastoma multiforme.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain; Cohort Studies; Dacarbazine; Dose-Response Relationship, Drug; Female; Glioblastoma; HIV Protease Inhibitors; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nelfinavir; Outcome Assessment, Health Care; Temozolomide; Time Factors | 2014 |
3 other study(ies) available for nelfinavir and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Modulation of CCAAT/enhancer binding protein homologous protein (CHOP)-dependent DR5 expression by nelfinavir sensitizes glioblastoma multiforme cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).
Topics: Activating Transcription Factor 4; Apoptosis; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glioblastoma; HIV Protease Inhibitors; Humans; Nelfinavir; Neoplasm Proteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor CHOP; Unfolded Protein Response | 2011 |
HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cells.
Topics: Brain Neoplasms; Cell Line, Tumor; Collagen; Drug Combinations; Gene Expression Regulation, Neoplastic; Glioblastoma; HIV Protease Inhibitors; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Laminin; Nelfinavir; Neovascularization, Pathologic; Proteoglycans; Signal Transduction; Time Factors; Vascular Endothelial Growth Factor A | 2006 |
Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Interactions; Drug Resistance, Neoplasm; Female; Glioblastoma; Humans; Mice; Mice, Nude; Nelfinavir; Phosphatidylinositol 3-Kinases; Protease Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Radiation Tolerance; Temozolomide | 2007 |