nefopam has been researched along with Renal Insufficiency in 1 studies
Nefopam: Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for the relief of acute and chronic pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p26)
nefopam : A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine : A member of the class of benzoxazocines that is 3,4,5,6-tetrahydro-1H-2,5-benzoxazocine substituted by phenyl and methyl groups at positions 1 and 5 respectively.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nefopam is a nonmorphinic central analgesic, for which no recommendation exists concerning adaptation of regimen in aged patients with or without renal impairment." | 1.40 | Population pharmacokinetics of nefopam in elderly, with or without renal impairment, and its link to treatment response. ( Djerada, Z; Fournet-Fayard, A; Gozalo, C; Lamiable, D; Lelarge, C; Malinovsky, JM; Millart, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Djerada, Z | 1 |
| Fournet-Fayard, A | 1 |
| Gozalo, C | 1 |
| Lelarge, C | 1 |
| Lamiable, D | 1 |
| Millart, H | 1 |
| Malinovsky, JM | 1 |
1 other study available for nefopam and Renal Insufficiency
| Article | Year |
|---|---|
Population pharmacokinetics of nefopam in elderly, with or without renal impairment, and its link to treatment response.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Area Under Curve; Female; Glomerular Filtration R | 2014 |