Page last updated: 2024-10-31

nefopam and Pregnancy

nefopam has been researched along with Pregnancy in 8 studies

Nefopam: Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for the relief of acute and chronic pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p26)
nefopam : A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine : A member of the class of benzoxazocines that is 3,4,5,6-tetrahydro-1H-2,5-benzoxazocine substituted by phenyl and methyl groups at positions 1 and 5 respectively.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Nefopam is a centrally acting analgesic which has a theoretical risk of stopping lactation due to its anticholinergic and dopaminergic effects."2.84The effect of nefopam on lactation after caesarean section: a single-blind randomised trial. ( Baka, NE; Bouaziz, H; Guerci, P; Hubert, C; Iohom, G; Rouabah, M; Vial, F, 2017)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baka, NE1
Vial, F1
Iohom, G1
Guerci, P1
Hubert, C1
Rouabah, M1
Bouaziz, H1
Deras, P1
Bonnal, A1
Barbier, M1
Morau, E1
Colson, P1
Lamazou, F1
Ouzounian, S1
Dupas, C1
Christin-Maitre, S1
Mialon, O1
Delotte, J1
Lehert, P1
Donzeau, M1
Drici, M1
Isnard, V1
Bongain, A1
Bloomfield, SS1
Barden, TP1
Mitchell, J1
Case, MT1
Smith, JK1
Nelson, RA1
Lacroix, X1
Prud'hon, MC1
Muguet, D1
Moskovtchenko, JF1
Liu, DT1
Savage, JM1
Donnell, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Placebo Controlled, Double-Blind, Single Dose Study To Evaluate The Safety And Tolerability Of Cream In Burn Patients With Induced Dermal Incisions[NCT04685577]Phase 260 participants (Anticipated)Interventional2022-07-10Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for nefopam and Pregnancy

ArticleYear
The effect of nefopam on lactation after caesarean section: a single-blind randomised trial.
    International journal of obstetric anesthesia, 2017, Volume: 31

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, Obstetrical; Anesthesia, Spinal; Body We

2017
Nefopam and propoxyphene in episiotomy pain.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Dextropropoxyphene; Double-Blind Method; Drug Evaluation; Episiotomy; Female; Hum

1980

Other Studies

6 other studies available for nefopam and Pregnancy

ArticleYear
[Assessment of practices in postoperative analgesia in caesarean before and after implementation of an information program].
    Annales francaises d'anesthesie et de reanimation, 2013, Volume: 32, Issue:6

    Topics: Acetaminophen; Adult; Analgesia, Obstetrical; Analgesics; Anesthesia, General; Anesthesia, Obstetric

2013
[Watch out for headaches at the end of a pregnancy! Do not miss an autoimmune hypositys].
    Gynecologie, obstetrique & fertilite, 2010, Volume: 38, Issue:4

    Topics: Autoimmune Diseases; Bromocriptine; Cesarean Section; Female; Headache; Humans; Magnetic Resonance I

2010
[Comparison between two analgesic protocols on IVF success rates].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 2011, Volume: 40, Issue:2

    Topics: Acetaminophen; Adult; Alprazolam; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Em

2011
Reproductive, acute and subacute toxicity studies with nefopam in laboratory animals.
    Toxicology and applied pharmacology, 1975, Volume: 33, Issue:1

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Dogs; Female; Hemorrhage; Inflammation;

1975
[Ketoprofen and nefopam in postoperative analgesia after cesarean section].
    Cahiers d'anesthesiologie, 1987, Volume: 35, Issue:4

    Topics: Cesarean Section; Female; Humans; Ketoprofen; Nefopam; Oxazocines; Pain, Postoperative; Phenylpropio

1987
Nefopam excretion in human milk.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:1

    Topics: Adult; Chromatography, High Pressure Liquid; Female; Humans; Milk, Human; Nefopam; Oxazocines; Pregn

1987