nefopam has been researched along with Pain, Postoperative in 81 studies
Nefopam: Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for the relief of acute and chronic pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p26)
nefopam : A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine : A member of the class of benzoxazocines that is 3,4,5,6-tetrahydro-1H-2,5-benzoxazocine substituted by phenyl and methyl groups at positions 1 and 5 respectively.
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study comparatively evaluated the effect of patient-controlled analgesia (PCA) regimens using equipotent doses of nefopam or fentanyl during laparoscopic gynecological surgery on postoperative nausea and vomiting (PONV)." | 9.20 | Effect of nefopam- versus fentanyl-based patient-controlled analgesia on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a prospective double-blind randomized controlled trial. ( Jung, E; Kim, SH; Lee, SJ; Oh, CS, 2015) |
| "Given preemptively, nefopam may be effective at improving postoperative pain management and at reducing the risk of developing postoperative chronic pain, because the drug has both analgesic and antihyperalgesic properties." | 7.75 | Long-term pain vulnerability after surgery in rats: prevention by nefopam, an analgesic with antihyperalgesic properties. ( Chateauraynaud, J; Laboureyras, E; Richebé, P; Simonnet, G, 2009) |
| "Intraoperative nefopam decreased postoperative pain and opioid consumption in the acute postoperative period after laparoscopic gastrectomy." | 6.87 | Intraoperative Nefopam Reduces Acute Postoperative Pain after Laparoscopic Gastrectomy: a Prospective, Randomized Study. ( Jo, J; Koo, BW; Na, HS; Nam, SW; Oh, AY; Park, JH; Ryu, JH, 2018) |
| "Acute postoperative pain, the need for rescue analgesics, and other postoperative adverse effects were assessed at 1, 6, 24, and 48 h postoperatively." | 6.87 | The Effect of Intraoperative Nefopam Administration on Acute Postoperative Pain and Chronic Discomfort After Robotic or Endoscopic Assisted Thyroidectomy: A Randomized Clinical Trial. ( Choi, JY; Hwang, JW; Jeon, YT; Kim, BG; Moon, JY; Oh, AY; Park, IS; Ryu, JH, 2018) |
| "Ketorolac was given at the end of surgery, and meloxicam was prescribed in the postoperative period to all patients in both groups." | 6.82 | Preventive Analgesic Efficacy of Nefopam in Acute and Chronic Pain After Breast Cancer Surgery: A Prospective, Double-Blind, and Randomized Trial. ( Han, JW; Koo, BW; Lim, DJ; Na, HS; Oh, AY; Ryu, JH, 2016) |
| "Nefopam is a centrally-acting but non-opioid analgesic drug of the benzoxazocine chemical class, developed in the early 1970s." | 6.45 | Single dose oral nefopam for acute postoperative pain in adults. ( Derry, S; Kakkar, M; McQuay, HJ; Moore, RA, 2009) |
| "This study comparatively evaluated the effect of patient-controlled analgesia (PCA) regimens using equipotent doses of nefopam or fentanyl during laparoscopic gynecological surgery on postoperative nausea and vomiting (PONV)." | 5.20 | Effect of nefopam- versus fentanyl-based patient-controlled analgesia on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a prospective double-blind randomized controlled trial. ( Jung, E; Kim, SH; Lee, SJ; Oh, CS, 2015) |
| " Nausea was significantly more common in the fentanyl group compared with both other groups." | 5.19 | The analgesic efficacy and safety of nefopam in patient-controlled analgesia after cardiac surgery: A randomized, double-blind, prospective study. ( Choi, DK; Choi, IC; Kim, K; Kim, WJ; Lee, YK; Sim, JY, 2014) |
| "3-mg/kg bolus of nefopam at the induction of anesthesia followed by a continuous infusion of 0." | 5.17 | Effects of nefopam on early postoperative hyperalgesia after cardiac surgery. ( Branchard, O; Cahana, A; Janvier, G; Jelacic, S; Leproust, S; Picard, W; Richebé, P; Rivat, C, 2013) |
| " A comparison was made of morphine and nefopam in 74 patients who required parenteral analgesia for moderate to severe postoperative and somatic pain, using a single administration, 2-dose level, double-blind design." | 5.04 | Nefopam and morphine in man. ( Laska, E; Sunshine, A, 1975) |
| "nefopam is a non-opioid, centrally-acting analgesic, frequently prescribed in France for acute pain and postoperatively." | 4.12 | Nefopam prescribing preferences in French hospitals: results of a survey. ( Aubrun, F; Dziadzko, M; Lalande, L; Schulz, T, 2022) |
| "Given preemptively, nefopam may be effective at improving postoperative pain management and at reducing the risk of developing postoperative chronic pain, because the drug has both analgesic and antihyperalgesic properties." | 3.75 | Long-term pain vulnerability after surgery in rats: prevention by nefopam, an analgesic with antihyperalgesic properties. ( Chateauraynaud, J; Laboureyras, E; Richebé, P; Simonnet, G, 2009) |
| " Based on a clinical observation of synergism between nefopam, a centrally acting non-opioid that inhibits monoamines reuptake, and ketoprofen, a non-steroidal anti-inflammatory drug, the objective of this study was to further explore this antinociceptive synergy in four distinct animal models of pain (both drugs were administered subcutaneously)." | 3.74 | Nefopam and ketoprofen synergy in rodent models of antinociception. ( Coppé, MC; Gillardin, JM; Girard, P; Pansart, Y; Verniers, D, 2008) |
| " The primary outcome was the dosage of fentanyl-nefopam IV-PCA infused over 24 h postoperatively." | 3.11 | Effect of remifentanil on post-operative analgesic consumption in patients undergoing shoulder arthroplasty after interscalene brachial plexus block: a randomized controlled trial. ( Bae, H; Kim, JT; Kim, Y; Lim, YJ; Park, SK; Sakura, S; Yoo, S, 2022) |
| "Variables related to chronic postsurgical pain (CPSP) were also investigated by telephone interviews with patients at 3 months postoperative." | 3.11 | Effect of Continuous Infusion of Intravenous Nefopam on Postoperative Opioid Consumption After Video-assisted Thoracic Surgery: A Double-blind Randomized Controlled Trial. ( Bahk, J; Lee, HB; Lee, HJ; Na, KJ; Park, S; Yoon, S, 2022) |
| "Nefopam is a non-opioid, non-nonsteroidal anti-imflammatory drug, analgesic drug that inhibits the reuptake of serotonin, norepinephrine, and dopamine." | 3.11 | Postoperative analgesia of intraoperative nefopam in patients undergoing anterior cervical spine surgery: A prospective randomized controlled trial. ( Homprasert, C; Nitising, A; Pantubtim, C; Raksakietisak, M; Rushatamukayanunt, P; Sawasdiwipachai, P; Wilaiwan, K, 2022) |
| "Nefopam is a useful agent for contemporary pain control after TKA." | 3.11 | Does Nefopam Provide Analgesic Effect and Reduce Morphine Consumption After Primary Total Knee Arthroplasty? A Prospective, Double-Blind, Randomized Controlled Trial. ( Boontanapibul, K; Pinsornsak, P; Sukkarnkosol, S, 2022) |
| "Acute postoperative pain, the need for rescue analgesics, and other postoperative adverse effects were assessed at 1, 6, 24, and 48 h postoperatively." | 2.87 | The Effect of Intraoperative Nefopam Administration on Acute Postoperative Pain and Chronic Discomfort After Robotic or Endoscopic Assisted Thyroidectomy: A Randomized Clinical Trial. ( Choi, JY; Hwang, JW; Jeon, YT; Kim, BG; Moon, JY; Oh, AY; Park, IS; Ryu, JH, 2018) |
| "Intraoperative nefopam decreased postoperative pain and opioid consumption in the acute postoperative period after laparoscopic gastrectomy." | 2.87 | Intraoperative Nefopam Reduces Acute Postoperative Pain after Laparoscopic Gastrectomy: a Prospective, Randomized Study. ( Jo, J; Koo, BW; Na, HS; Nam, SW; Oh, AY; Park, JH; Ryu, JH, 2018) |
| "Postoperative pain was evaluated using a numerical pain scale (NPS)." | 2.87 | Median effective dose of nefopam to treat postoperative pain in patients who have undergone laparoscopic cholecystectomy. ( Kim, H; Lee, DK; Lee, M; Lee, MK, 2018) |
| "Nefopam is a centrally acting analgesic which has a theoretical risk of stopping lactation due to its anticholinergic and dopaminergic effects." | 2.84 | The effect of nefopam on lactation after caesarean section: a single-blind randomised trial. ( Baka, NE; Bouaziz, H; Guerci, P; Hubert, C; Iohom, G; Rouabah, M; Vial, F, 2017) |
| "This prospective randomized study suggested that nefopam in combination with paracetamol has no benefit after open abdominal surgery." | 2.84 | Opioid-sparing effect of nefopam in combination with paracetamol after major abdominal surgery: a randomized double-blind study. ( Alonso, S; Casano, F; Cuvillon, P; Demattei, C; L'hermite, J; Lefrant, JY; Muller, L; Ripart, J; Zoric, L, 2017) |
| "Morphine consumption was comparable between the two groups both at H48, 38 mg (26:52) (median, 25th:75th percentile) (control group) versus 43 mg (19:74) (ropivacaine group), and at H24, 18 mg (16:22) versus 22 mg (9:35) respectively." | 2.84 | Does continuous wound infiltration enhance baseline intravenous multimodal analgesia after posterior spinal fusion surgery? A randomized, double-blinded, placebo-controlled study. ( Albaladejo, P; Bosson, JL; Greze, J; Incagnoli, P; Palombi, O; Payen, JF; Quesada, JL; Tonetti, J; Vighetti, A, 2017) |
| " There were no other statistically significant between-group differences in the incidence of adverse events." | 2.82 | Opioid sparing effect and safety of nefopam in patient controlled analgesia after laparotomy: A randomized, double blind study. ( Cho, CW; Jin, HS; Kim, WJ; Kim, YC; Lee, C; Yoo, Y, 2016) |
| "Nefopam is an effective analgesic in bimaxillary osteotomy in that it can reduce the use of opioids and nonsteroidal anti-inflammatory drugs, thereby reducing the side effects of conventional analgesics." | 2.82 | Analgesic effects of nefopam in patients undergoing bimaxillary osteotomy: A double-blind, randomized, placebo-controlled study. ( Moon, YE; Park, HJ; Park, JU; Yoo, W, 2016) |
| "Ketorolac was given at the end of surgery, and meloxicam was prescribed in the postoperative period to all patients in both groups." | 2.82 | Preventive Analgesic Efficacy of Nefopam in Acute and Chronic Pain After Breast Cancer Surgery: A Prospective, Double-Blind, and Randomized Trial. ( Han, JW; Koo, BW; Lim, DJ; Na, HS; Oh, AY; Ryu, JH, 2016) |
| "Nefopam is a centrally-acting non-opioid analgesic, which has no effect on bleeding time and platelet aggregation." | 2.80 | A Randomized Clinical Trial of Nefopam versus Ketorolac Combined With Oxycodone in Patient-Controlled Analgesia after Gynecologic Surgery. ( Hwang, BY; Kim, E; Kim, HK; Kim, TK; Kwon, JY; Lee, DW, 2015) |
| "Nefopam has been used as an adjuvant to opioid analgesia after operation." | 2.80 | Nefopam as an adjunct to intravenous patient-controlled analgesia after renal transplantation: a randomised trial. ( Choi, YS; Huh, KH; Kim, SY; Oh, YJ; Park, J; Roh, YH, 2015) |
| "Prevalence of neuropathic pain was 10." | 2.79 | Pain and recovery after total knee arthroplasty: a 12-month follow-up after a prospective randomized study evaluating Nefopam and Ketamine for early rehabilitation. ( Aveline, C; Bonnet, F; Cognet, F; Gautier, JF; Hetet, HL; Roux, AL; Vautier, P, 2014) |
| "Postoperative pain was treated successfully in both groups." | 2.78 | Ondansetron does not attenuate the analgesic efficacy of nefopam. ( Chen, J; Chen, Y; Li, MG; Lu, KZ; Shen, H; Tian, GP, 2013) |
| "001), resulting in higher mean nefopam peak concentration (121 and 223 ng/mL vs." | 2.75 | Nefopam pharmacokinetics in patients with end-stage renal disease. ( Chauvet, S; Couet, W; Debaene, B; Grégoire, N; Le Guern, ME; Levy, RH; Marchand, S; Mimoz, O; Saleh, A, 2010) |
| "Sufentanil was given during the intraoperative period for a 20% increase in arterial mean pressure or heart rate in a patient with a bispectral index between 40 and 60." | 2.73 | Analgesic efficacy of bilateral superficial cervical plexus block administered before thyroid surgery under general anaesthesia. ( Amrouni, H; Andrieu, G; Carnaille, B; Lebuffe, G; Pattou, F; Robin, E; Vallet, B; Wattier, JM, 2007) |
| "Pretreatment with nefopam could be useful to prevent pain sensitization induced by opioids." | 2.72 | The effect of nefopam on morphine overconsumption induced by large-dose remifentanil during propofol anesthesia for major abdominal surgery. ( Clevenot, D; Debaene, B; Derrode, N; Fletcher, D; Rolland, D; Tirault, M, 2006) |
| "Morphine titration was successful in all ketamine and nefopam patients but failed in four control patients (two because of respiratory toxicity and two because of persistent pain)." | 2.71 | Nefopam and ketamine comparably enhance postoperative analgesia. ( Alfonsi, P; Chauvin, M; Guignard, B; Kapfer, B; Sessler, DI, 2005) |
| " Adverse effects were comparable in the three groups, except for significantly more nausea in the control group (39% vs." | 2.70 | Analgesic efficacy and safety of nefopam vs. propacetamol following hepatic resection. ( Fletcher, D; Gillon, MC; Incagnoli, P; Josse, C; Kuhlman, L; Mimoz, O; Mirand, A; Soilleux, H, 2001) |
| "Nefopam led to a 30% increase in heart rate for one hour (p less than 0." | 2.67 | [Analgesic and respiratory effects of nalbuphine during the immediate postoperative period in thoracotomy]. ( Boileau, S; Boulanger, G; Laxenaire, MC; Louppe, B; Manel, J, 1990) |
| "Nefopam 0." | 2.65 | Nefopam in postoperative pain. ( Phillips, G; Vickers, MD, 1979) |
| " In the oxycodone group, only two patients (12%) needed maximal dosage (6 x 4 mg), one of them requiring 32 mg of oxycodone." | 2.65 | Comparison of the analgesic dose-effect relationships of nefopam and oxycodone in postoperative pain. ( Leander, P; Tammisto, T; Tigerstedt, I, 1979) |
| "Nefopam was found by observer preference to be significantly better than placebo in relieving post-operative pain." | 2.64 | A double-blind comparison of nefopam and placebo in post-operative pain. ( Hedges, A; Turner, P; Wadsworth, J, 1978) |
| "Nefopam 15 mg was equipotent with pethidine 50 mg, peak analgesia being achieved 1 h after the i." | 2.64 | Comparison of nefopam and pethidine in postoperative pain. ( Sipponen, J; Tammisto, T; Tigerstedt, I; Turunen, M, 1977) |
| "Primary outcomes were postoperative pain scores and opioid consumption." | 2.58 | The efficacy and safety of nefopam for pain relief during laparoscopic cholecystectomy: A meta-analysis. ( Shen, Z; Sheng, S; Zhao, T, 2018) |
| "Nefopam is a centrally-acting but non-opioid analgesic drug of the benzoxazocine chemical class, developed in the early 1970s." | 2.45 | Single dose oral nefopam for acute postoperative pain in adults. ( Derry, S; Kakkar, M; McQuay, HJ; Moore, RA, 2009) |
| "Haemolysis was <5% which signified haemocompatibility of formulation." | 1.48 | Nefopam hydrochloride loaded microspheres for post-operative pain management: synthesis, physicochemical characterization and in-vivo evaluation. ( Arora, S; Madan, J; Sharma, N, 2018) |
| "In the postoperative pain model, at 30 mg x kg(-1) nefopam augmented the endpoint to thermal threshold, 60 and 90 minutes after administration compared to the threshold recorded after the incision." | 1.31 | Nefopam reduces thermal hypersensitivity in acute and postoperative pain models in the rat. ( Coppe, MC; Gillardin, JM; Girard, P; Pansart, Y, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (22.22) | 18.7374 |
| 1990's | 4 (4.94) | 18.2507 |
| 2000's | 19 (23.46) | 29.6817 |
| 2010's | 29 (35.80) | 24.3611 |
| 2020's | 11 (13.58) | 2.80 |
| Authors | Studies |
|---|---|
| Pinsornsak, P | 1 |
| Sukkarnkosol, S | 1 |
| Boontanapibul, K | 1 |
| Li, S | 1 |
| Li, P | 1 |
| Wang, R | 1 |
| Li, H | 1 |
| Schulz, T | 1 |
| Lalande, L | 1 |
| Aubrun, F | 3 |
| Dziadzko, M | 1 |
| Kim, Y | 1 |
| Bae, H | 1 |
| Yoo, S | 1 |
| Park, SK | 1 |
| Lim, YJ | 1 |
| Sakura, S | 1 |
| Kim, JT | 1 |
| Yoon, S | 1 |
| Lee, HB | 1 |
| Na, KJ | 1 |
| Park, S | 1 |
| Bahk, J | 1 |
| Lee, HJ | 1 |
| Raksakietisak, M | 1 |
| Rushatamukayanunt, P | 1 |
| Wilaiwan, K | 1 |
| Homprasert, C | 1 |
| Nitising, A | 1 |
| Sawasdiwipachai, P | 1 |
| Pantubtim, C | 1 |
| Charoenpol, FN | 1 |
| Khampitak, N | 1 |
| Aimnang, C | 1 |
| Pachirat, K | 1 |
| Sirithanaphol, W | 1 |
| Rompsaithong, U | 1 |
| Kiatsopit, P | 1 |
| Lumbiganon, S | 1 |
| Du, YT | 1 |
| Xue, FS | 1 |
| Li, CW | 1 |
| Crestani, A | 1 |
| Bibaoune, A | 1 |
| Le Gac, M | 1 |
| Dabi, Y | 1 |
| Kolanska, K | 1 |
| Ferrier, C | 1 |
| Bendifallah, S | 1 |
| Touboul, C | 1 |
| Darai, E | 1 |
| Lim, H | 1 |
| Kang, S | 1 |
| Kim, B | 1 |
| Ko, S | 1 |
| Capuco, A | 1 |
| Urits, I | 1 |
| Orhurhu, V | 1 |
| Chun, R | 1 |
| Shukla, B | 1 |
| Burke, M | 1 |
| Kaye, RJ | 1 |
| Garcia, AJ | 1 |
| Kaye, AD | 1 |
| Viswanath, O | 1 |
| Pasutharnchat, K | 1 |
| Wichachai, W | 1 |
| Buachai, R | 1 |
| Sharma, N | 1 |
| Arora, S | 1 |
| Madan, J | 1 |
| Baka, NE | 1 |
| Vial, F | 1 |
| Iohom, G | 2 |
| Guerci, P | 1 |
| Hubert, C | 1 |
| Rouabah, M | 1 |
| Bouaziz, H | 2 |
| Kim, BG | 1 |
| Moon, JY | 1 |
| Choi, JY | 1 |
| Park, IS | 1 |
| Oh, AY | 3 |
| Jeon, YT | 1 |
| Hwang, JW | 1 |
| Ryu, JH | 3 |
| Na, HS | 2 |
| Koo, BW | 2 |
| Nam, SW | 1 |
| Jo, J | 1 |
| Park, JH | 1 |
| Oh, YN | 1 |
| Kim, KN | 1 |
| Jeong, MA | 1 |
| Kim, DW | 1 |
| Kim, JY | 1 |
| Ki, HS | 1 |
| Zhao, T | 1 |
| Shen, Z | 1 |
| Sheng, S | 1 |
| Kendall, MC | 1 |
| Castro-Alves, LJ | 1 |
| Kim, H | 1 |
| Lee, DK | 1 |
| Lee, MK | 1 |
| Lee, M | 1 |
| Beloeil, H | 5 |
| Albaladejo, P | 2 |
| Sion, A | 1 |
| Durand, M | 1 |
| Martinez, V | 2 |
| Lasocki, S | 1 |
| Futier, E | 1 |
| Verzili, D | 1 |
| Minville, V | 1 |
| Fessenmeyer, C | 1 |
| Belbachir, A | 1 |
| Renault, A | 1 |
| Bellissant, E | 1 |
| Deras, P | 1 |
| Bonnal, A | 1 |
| Barbier, M | 1 |
| Morau, E | 1 |
| Colson, P | 1 |
| Corbonnois, G | 1 |
| Lazarescu, C | 1 |
| Hubert, I | 1 |
| Aveline, C | 2 |
| Roux, AL | 1 |
| Hetet, HL | 2 |
| Gautier, JF | 2 |
| Vautier, P | 2 |
| Cognet, F | 2 |
| Bonnet, F | 2 |
| Lu, KZ | 1 |
| Shen, H | 1 |
| Chen, Y | 1 |
| Li, MG | 1 |
| Tian, GP | 1 |
| Chen, J | 1 |
| Kim, K | 1 |
| Kim, WJ | 2 |
| Choi, DK | 1 |
| Lee, YK | 1 |
| Choi, IC | 1 |
| Sim, JY | 1 |
| Kim, SY | 1 |
| Huh, KH | 1 |
| Roh, YH | 1 |
| Oh, YJ | 1 |
| Park, J | 1 |
| Choi, YS | 1 |
| Oh, CS | 1 |
| Jung, E | 1 |
| Lee, SJ | 1 |
| Kim, SH | 1 |
| Hwang, BY | 1 |
| Kwon, JY | 1 |
| Lee, DW | 1 |
| Kim, E | 1 |
| Kim, TK | 1 |
| Kim, HK | 1 |
| Jolly, C | 1 |
| Jathières, F | 1 |
| Keïta, H | 1 |
| Jaouen, E | 1 |
| Guyot, B | 1 |
| Torre, A | 1 |
| Park, HJ | 1 |
| Park, JU | 1 |
| Yoo, W | 1 |
| Moon, YE | 1 |
| Greze, J | 1 |
| Vighetti, A | 1 |
| Incagnoli, P | 2 |
| Quesada, JL | 1 |
| Palombi, O | 1 |
| Tonetti, J | 1 |
| Bosson, JL | 1 |
| Payen, JF | 1 |
| Lim, DJ | 1 |
| Han, JW | 1 |
| Jin, HS | 1 |
| Kim, YC | 1 |
| Yoo, Y | 1 |
| Lee, C | 1 |
| Cho, CW | 1 |
| Marret, E | 1 |
| Fletcher, D | 4 |
| Ravaud, P | 1 |
| Trinquart, L | 1 |
| Cuvillon, P | 1 |
| Zoric, L | 1 |
| Demattei, C | 1 |
| Alonso, S | 1 |
| Casano, F | 1 |
| L'hermite, J | 1 |
| Ripart, J | 1 |
| Lefrant, JY | 1 |
| Muller, L | 1 |
| Attali, JY | 1 |
| Leconte, V | 1 |
| Leborgne, P | 1 |
| Evans, MS | 1 |
| Lysakowski, C | 1 |
| Tramèr, MR | 1 |
| Kakkar, M | 1 |
| Derry, S | 1 |
| Moore, RA | 1 |
| McQuay, HJ | 1 |
| Laboureyras, E | 1 |
| Chateauraynaud, J | 1 |
| Richebé, P | 2 |
| Simonnet, G | 1 |
| Mimoz, O | 2 |
| Chauvet, S | 1 |
| Grégoire, N | 1 |
| Marchand, S | 1 |
| Le Guern, ME | 2 |
| Saleh, A | 1 |
| Couet, W | 1 |
| Debaene, B | 2 |
| Levy, RH | 1 |
| Picard, W | 1 |
| Rivat, C | 1 |
| Jelacic, S | 1 |
| Branchard, O | 1 |
| Leproust, S | 1 |
| Cahana, A | 1 |
| Janvier, G | 1 |
| Van Elstraete, AC | 1 |
| Sitbon, P | 1 |
| Remérand, F | 1 |
| Le Tendre, C | 1 |
| Rosset, P | 1 |
| Peru, R | 1 |
| Favard, L | 1 |
| Pourrat, X | 1 |
| Laffon, M | 1 |
| Fusciardi, J | 1 |
| Du Manoir, B | 1 |
| Langlois, M | 1 |
| Alquier, C | 1 |
| Chauvin, M | 2 |
| Tramoni, G | 1 |
| Viale, JP | 1 |
| Cazals, C | 1 |
| Bhageerutty, K | 1 |
| Delage, N | 2 |
| Nègre, I | 1 |
| Mazoit, JX | 3 |
| Benhamou, D | 3 |
| Kapfer, B | 1 |
| Alfonsi, P | 1 |
| Guignard, B | 1 |
| Sessler, DI | 1 |
| Merle, JC | 1 |
| Vandroux, D | 1 |
| Odin, I | 1 |
| Dupuis, JL | 1 |
| Bougault, A | 1 |
| Mehaddi, Y | 1 |
| Nathan, N | 1 |
| Maaliki, H | 1 |
| Tirault, M | 1 |
| Derrode, N | 1 |
| Clevenot, D | 1 |
| Rolland, D | 1 |
| Ould-Ahmed, M | 1 |
| Drouillard, I | 1 |
| El-Kartouti, A | 1 |
| Wey, PF | 1 |
| Lions, C | 1 |
| Martinez, JY | 1 |
| Eurin, M | 1 |
| Thévenin, A | 1 |
| Andrieu, G | 1 |
| Amrouni, H | 1 |
| Robin, E | 1 |
| Carnaille, B | 1 |
| Wattier, JM | 1 |
| Pattou, F | 1 |
| Vallet, B | 1 |
| Lebuffe, G | 1 |
| Looi, YC | 1 |
| Audisio, RA | 1 |
| Girard, P | 2 |
| Verniers, D | 1 |
| Coppé, MC | 2 |
| Pansart, Y | 2 |
| Gillardin, JM | 2 |
| Abeloos, J | 1 |
| Rolly, G | 2 |
| Uten, M | 1 |
| Bloomfield, SS | 1 |
| Barden, TP | 1 |
| Mitchell, J | 1 |
| Eduah, SB | 1 |
| Sidhu, BS | 1 |
| Khichy, S | 1 |
| Singh, KH | 1 |
| Josse, C | 1 |
| Gillon, MC | 1 |
| Kuhlman, L | 1 |
| Mirand, A | 1 |
| Soilleux, H | 1 |
| Taylor, MS | 1 |
| Beaver, WT | 1 |
| Feise, GA | 1 |
| Tigerstedt, I | 2 |
| Sipponen, J | 1 |
| Tammisto, T | 2 |
| Turunen, M | 1 |
| Hedges, A | 1 |
| Wadsworth, J | 1 |
| Turner, P | 1 |
| Phillips, G | 1 |
| Vickers, MD | 1 |
| Leander, P | 1 |
| Versichelen, L | 1 |
| Schmidt, M | 1 |
| Trop, D | 1 |
| Kenny, L | 1 |
| Grad, BR | 1 |
| Sunshine, A | 1 |
| Laska, E | 1 |
| Louppe, B | 1 |
| Manel, J | 1 |
| Boileau, S | 1 |
| Boulanger, G | 1 |
| Laxenaire, MC | 1 |
| Goucke, CR | 1 |
| Keaveny, JP | 1 |
| Kay, B | 1 |
| Healy, TE | 1 |
| Ryan, M | 1 |
| Moffat, AC | 1 |
| Kenny, GN | 2 |
| Prentice, JW | 1 |
| Pandit, PN | 1 |
| Oke, VG | 1 |
| Jha, RJ | 1 |
| Bowalekar, SK | 1 |
| Raghu, CN | 1 |
| McLintock, TT | 1 |
| Howie, JC | 1 |
| McArdle, CS | 1 |
| Lawrie, S | 1 |
| Aitken, H | 1 |
| Novelli, GP | 1 |
| Casali, R | 1 |
| Masci, P | 1 |
| Piscitelli, P | 1 |
| Lacroix, X | 1 |
| Prud'hon, MC | 1 |
| Muguet, D | 1 |
| Moskovtchenko, JF | 1 |
| Calmi, D | 1 |
| Pagnoni, B | 1 |
| Tiengo, M | 1 |
| Ravanelli, A | 1 |
| Savio, G | 1 |
| Dal Prà, ML | 1 |
| Hannington-Kiff, JG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Efficacy of Perioperative Administration of Tianeptine Versus Pregabalin on Acute and Chronic Post Mastectomy Pain After Breast Cancer Surgery. A Double-Blinded Randomized Controlled Trial.[NCT05935059] | 90 participants (Anticipated) | Interventional | 2023-06-21 | Recruiting | |||
| Effect of Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Block on the Incidence of Post Mastectomy Pain Syndrome, Randomized Double Blinded Controlled Study[NCT05201963] | 120 participants (Anticipated) | Interventional | 2021-11-01 | Recruiting | |||
| Prospective, Controlled Versus Placebo, Randomized, Double-blind Study, Evaluating the Value of Non-opioid Analgesic Combination (Based on Paracetamol, Nefopam, Ketoprofen) for Postoperative Analgesia.[NCT01882530] | Phase 4 | 223 participants (Actual) | Interventional | 2013-07-23 | Terminated (stopped due to Practice on postoperative pain management changed) | ||
| Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Patients: Randomized Double-blind Controlled Study[NCT05071352] | Phase 3 | 60 participants (Anticipated) | Interventional | 2021-10-01 | Recruiting | ||
| A Randomized Controlled Trial on the Effect and Safety of Intravenous Nefopam/Fentanyl Postoperative Patient-Controlled-Analgesia in Patients Undergoing Laparotomy[NCT02596269] | Phase 2/Phase 3 | 73 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
| The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis[NCT04033562] | Phase 4 | 2 participants (Actual) | Interventional | 2020-01-15 | Terminated (stopped due to limited enrollment and unable to enroll subjects to reach statistical significance) | ||
| Efficacy of a Single-shot Wound Infiltration With Bupivacaine/Adrenalin During Cesarean Section in Reducing Postoperative Pain. A Randomized Prospective Controlled Trial[NCT03395912] | 288 participants (Actual) | Interventional | 2018-01-25 | Completed | |||
| Effect of Nefopam on Acute Postoperative Pain in Patients Undergoing Orthognathic Surgery[NCT01461031] | 40 participants (Actual) | Interventional | 2011-10-31 | Completed | |||
| Efficacy of Continuous Wound Infusion in Major Lumbar and Thoracic Spine Surgery : A Randomised, Double-blinded, Placebo-controlled Study[NCT01743794] | Phase 2/Phase 3 | 60 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| Analgesic Effectiveness of Nefopam in Patients Undergoing Anterior Cervical Spine Surgery[NCT03955705] | 50 participants (Anticipated) | Interventional | 2019-05-15 | Enrolling by invitation | |||
| Low Dose Ketamine Infusion for Postoperative Analgesia After Total Knee Arthroplasty: Optimum Dose to Reduce Morphine Consumption[NCT04085588] | 75 participants (Actual) | Observational | 2019-04-15 | Completed | |||
| Study of the Effects of Nefopam on Hyperalgesia Following Sternotomy in Cardiac Surgery[NCT00413257] | Phase 2/Phase 3 | 90 participants (Actual) | Interventional | 2006-12-31 | Completed | ||
| Effects of Continuous Infusion of Intravenous Nefopam on Postoperative Pain and Opioid Consumption After Video Assisted Thoracic Surgery: A Double Blind Randomized Controlled Trial[NCT04450355] | 90 participants (Actual) | Interventional | 2020-07-30 | Completed | |||
| The Effect of Acute Intravenous Morphine Administration on Sleep Disordered Breathing (SDB) in Patients With Moderate Obstructive Sleep Apnoea (OSA): A Paired Design Trial[NCT03127800] | Phase 3 | 6 participants (Actual) | Interventional | 2016-05-20 | Terminated (stopped due to Difficulties with recruitment) | ||
| Evaluation of the Postoperative Analgesic Efficacy of Bilateral Superficial Cervical Block for Thyroidectomy and Mini Incision Under General Balanced Anesthesia: a Randomized, Triple Masked, Placebo Controlled Trial.[NCT01171885] | Phase 4 | 120 participants (Anticipated) | Interventional | 2009-07-31 | Recruiting | ||
| Antagonism Research Between Antiemetics Agents (Droperidol, Dexametasone, Ondansetron) and Acetaminophen in Thyroidectomy's Post-operative Analgesia.[NCT01679093] | Phase 3 | 66 participants (Actual) | Interventional | 2009-06-30 | Completed | ||
| [NCT01833728] | 16 participants (Actual) | Interventional | 2013-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for nefopam and Pain, Postoperative
| Article | Year |
|---|---|
Different interventions for preventing postoperative catheter-related bladder discomfort: a systematic review and meta-analysis.
Topics: Chlorpheniramine; Dexmedetomidine; Gabapentin; Haloperidol; Humans; Ketamine; Lidocaine; Meperidine; | 2022 |
A Comprehensive Review of the Diagnosis, Treatment, and Management of Postmastectomy Pain Syndrome.
Topics: Acetylcholine Release Inhibitors; Analgesics; Anesthesia, Conduction; Anesthetics, Local; Antidepres | 2020 |
A Comprehensive Review of the Diagnosis, Treatment, and Management of Postmastectomy Pain Syndrome.
Topics: Acetylcholine Release Inhibitors; Analgesics; Anesthesia, Conduction; Anesthetics, Local; Antidepres | 2020 |
A Comprehensive Review of the Diagnosis, Treatment, and Management of Postmastectomy Pain Syndrome.
Topics: Acetylcholine Release Inhibitors; Analgesics; Anesthesia, Conduction; Anesthetics, Local; Antidepres | 2020 |
A Comprehensive Review of the Diagnosis, Treatment, and Management of Postmastectomy Pain Syndrome.
Topics: Acetylcholine Release Inhibitors; Analgesics; Anesthesia, Conduction; Anesthetics, Local; Antidepres | 2020 |
The efficacy and safety of nefopam for pain relief during laparoscopic cholecystectomy: A meta-analysis.
Topics: Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; Chi-Square Distribution; | 2018 |
Non-opioid analgesics in adults after major surgery: systematic review with network meta-analysis of randomized trials.
Topics: Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; Nefopam; Pain, Pos | 2017 |
Nefopam for the prevention of postoperative pain: quantitative systematic review.
Topics: Adult; Analgesics, Non-Narcotic; Humans; Nefopam; Pain Measurement; Pain, Postoperative; Randomized | 2008 |
Single dose oral nefopam for acute postoperative pain in adults.
Topics: Acute Disease; Administration, Oral; Adult; Analgesics, Non-Narcotic; Humans; Nefopam; Pain, Postope | 2009 |
A review of the literature on post-operative pain in older cancer patients.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Nefopam; Neoplas | 2007 |
Managing postoperative pain.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Hu | 2001 |
56 trials available for nefopam and Pain, Postoperative
| Article | Year |
|---|---|
Does Nefopam Provide Analgesic Effect and Reduce Morphine Consumption After Primary Total Knee Arthroplasty? A Prospective, Double-Blind, Randomized Controlled Trial.
Topics: Analgesics; Analgesics, Opioid; Antiemetics; Arthroplasty, Replacement, Knee; Double-Blind Method; H | 2022 |
Effect of remifentanil on post-operative analgesic consumption in patients undergoing shoulder arthroplasty after interscalene brachial plexus block: a randomized controlled trial.
Topics: Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Shoulder; Brachial Plexus Block; Delirium | 2022 |
Effect of Continuous Infusion of Intravenous Nefopam on Postoperative Opioid Consumption After Video-assisted Thoracic Surgery: A Double-blind Randomized Controlled Trial.
Topics: Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Nefopam; Pain, Postopera | 2022 |
Postoperative analgesia of intraoperative nefopam in patients undergoing anterior cervical spine surgery: A prospective randomized controlled trial.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Cervical Vertebrae; Double-Blind Method; Dr | 2022 |
Single-dose intravenous nefopam on postoperative catheter-related bladder discomfort in patients undergoing transurethral resection of prostate: a randomized, double-blind placebo-controlled trial.
Topics: Double-Blind Method; Humans; Male; Nefopam; Pain, Postoperative; Transurethral Resection of Prostate | 2023 |
Comments on "Effect of Continuous Infusion of Intravenous Nefopam on Postoperative Opioid Consumption After Video-assisted Thoracic Surgery: A Double-blind Randomized Controlled Trial".
Topics: Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Huma | 2023 |
Comparison Between Preoperative and Intraoperative Administration of Nefopam for Acute and Chronic Postoperative Pain in Colon Cancer Patients: A Prospective, Randomized, Double-Blind Study.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Chronic Pain; Colonic Neoplasms; Double-Blind Method; Female; | 2019 |
Analgesic efficacy of nefopam for cancer pain: a randomized controlled study.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Cancer Pain; Double-Blind Method; Female; Humans; Male; Middl | 2020 |
The effect of nefopam on lactation after caesarean section: a single-blind randomised trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, Obstetrical; Anesthesia, Spinal; Body We | 2017 |
The Effect of Intraoperative Nefopam Administration on Acute Postoperative Pain and Chronic Discomfort After Robotic or Endoscopic Assisted Thyroidectomy: A Randomized Clinical Trial.
Topics: Adult; Analgesics, Non-Narcotic; Double-Blind Method; Endoscopy; Female; Humans; Infusions, Intraven | 2018 |
Intraoperative Nefopam Reduces Acute Postoperative Pain after Laparoscopic Gastrectomy: a Prospective, Randomized Study.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Fe | 2018 |
Effects of nefopam with fentanyl in intravenous patient-controlled analgesia after arthroscopic orthopedic surgery: a prospective double-blind randomized trial
Topics: Administration, Intravenous; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non | 2018 |
Median effective dose of nefopam to treat postoperative pain in patients who have undergone laparoscopic cholecystectomy.
Topics: Adult; Analgesics, Non-Narcotic; Cholecystectomy, Laparoscopic; Dose-Response Relationship, Drug; Fe | 2018 |
Multicentre, prospective, double-blind, randomised controlled clinical trial comparing different non-opioid analgesic combinations with morphine for postoperative analgesia: the OCTOPUS study.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Do | 2019 |
Pain and recovery after total knee arthroplasty: a 12-month follow-up after a prospective randomized study evaluating Nefopam and Ketamine for early rehabilitation.
Topics: Aged; Analgesics; Arthroplasty, Replacement, Knee; Chronic Pain; Female; Follow-Up Studies; Humans; | 2014 |
Ondansetron does not attenuate the analgesic efficacy of nefopam.
Topics: Adult; Aged; Analgesics; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; | 2013 |
The analgesic efficacy and safety of nefopam in patient-controlled analgesia after cardiac surgery: A randomized, double-blind, prospective study.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, | 2014 |
Nefopam as an adjunct to intravenous patient-controlled analgesia after renal transplantation: a randomised trial.
Topics: Administration, Intravenous; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Female; | 2015 |
Effect of nefopam- versus fentanyl-based patient-controlled analgesia on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a prospective double-blind randomized controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Gyn | 2015 |
A Randomized Clinical Trial of Nefopam versus Ketorolac Combined With Oxycodone in Patient-Controlled Analgesia after Gynecologic Surgery.
Topics: Adolescent; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analges | 2015 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
Analgesic effects of nefopam in patients undergoing bimaxillary osteotomy: A double-blind, randomized, placebo-controlled study.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nefop | 2016 |
Does continuous wound infiltration enhance baseline intravenous multimodal analgesia after posterior spinal fusion surgery? A randomized, double-blinded, placebo-controlled study.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics; Female; Humans; Male; Middle Aged; | 2017 |
Preventive Analgesic Efficacy of Nefopam in Acute and Chronic Pain After Breast Cancer Surgery: A Prospective, Double-Blind, and Randomized Trial.
Topics: Acute Pain; Adult; Aged; Analgesics, Non-Narcotic; Axilla; Breast Neoplasms; Chemoradiotherapy, Adju | 2016 |
Opioid sparing effect and safety of nefopam in patient controlled analgesia after laparotomy: A randomized, double blind study.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Heart Rate | 2016 |
Opioid-sparing effect of nefopam in combination with paracetamol after major abdominal surgery: a randomized double-blind study.
Topics: Abdomen; Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Dru | 2017 |
Postoperative analgesia and early rehabilitation after total knee replacement: a comparison of continuous low-dose intravenous ketamine versus nefopam.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener | 2009 |
Nefopam pharmacokinetics in patients with end-stage renal disease.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Arteriovenous Shunt, Surgical; Biotransformation; Chromatogra | 2010 |
Effects of nefopam on early postoperative hyperalgesia after cardiac surgery.
Topics: Aged; Analgesics, Non-Narcotic; Anesthesia; Cardiac Surgical Procedures; Coronary Artery Bypass; Dou | 2013 |
Median effective dose (ED50) of paracetamol and nefopam for postoperative pain: isobolographic analysis of their antinociceptive interaction.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, General; Dose-Response Relationship, Dru | 2013 |
Randomized prospective study of the analgesic effect of nefopam after orthopaedic surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplas | 2003 |
Randomized prospective study of the analgesic effect of nefopam after orthopaedic surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplas | 2003 |
Randomized prospective study of the analgesic effect of nefopam after orthopaedic surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplas | 2003 |
Randomized prospective study of the analgesic effect of nefopam after orthopaedic surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplas | 2003 |
Morphine-sparing effect of nefopam by continuous intravenous injection after abdominal surgery by laparotomy.
Topics: Abdomen; Analgesics, Non-Narcotic; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blin | 2003 |
The median effective dose of nefopam and morphine administered intravenously for postoperative pain after minor surgery: a prospective randomized double-blinded isobolographic study of their analgesic action.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind | 2004 |
Nefopam and ketamine comparably enhance postoperative analgesia.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Do | 2005 |
[Analgesic effect of continuous intravenous nefopam after urological surgery].
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Meth | 2005 |
Median effective dose (ED50) of nefopam and ketoprofen in postoperative patients: a study of interaction using sequential analysis and isobolographic analysis.
Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Drug Therapy, Combi | 2005 |
The effect of nefopam on morphine overconsumption induced by large-dose remifentanil during propofol anesthesia for major abdominal surgery.
Topics: Adult; Aged; Digestive System Surgical Procedures; Double-Blind Method; Drug Tolerance; Female; Huma | 2006 |
Analgesic efficacy of bilateral superficial cervical plexus block administered before thyroid surgery under general anaesthesia.
Topics: Adult; Aged; Amides; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2007 |
Analgesic efficacy of bilateral superficial cervical plexus block administered before thyroid surgery under general anaesthesia.
Topics: Adult; Aged; Amides; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2007 |
Analgesic efficacy of bilateral superficial cervical plexus block administered before thyroid surgery under general anaesthesia.
Topics: Adult; Aged; Amides; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2007 |
Analgesic efficacy of bilateral superficial cervical plexus block administered before thyroid surgery under general anaesthesia.
Topics: Adult; Aged; Amides; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, | 2007 |
Double blind study with nefopam, tilidine and placebo, for postoperative pain suppression.
Topics: Adolescent; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Doub | 1983 |
Nefopam and propoxyphene in episiotomy pain.
Topics: Adolescent; Adult; Dextropropoxyphene; Double-Blind Method; Drug Evaluation; Episiotomy; Female; Hum | 1980 |
[Treatment of postoperative pain with Nefopam].
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Hysterectomy; Middle Aged; Nausea; Nefopam; Oxazocines | 1980 |
Comparative evaluation of intramuscular buprenorphine, pentazocine and nefopam in post-operative pain relief.
Topics: Adolescent; Adult; Buprenorphine; Female; Humans; Injections, Intramuscular; Intraoperative Period; | 1993 |
Analgesic efficacy and safety of nefopam vs. propacetamol following hepatic resection.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Ana | 2001 |
A comparison of the analgesic effect of intramuscular nefopam and morphine in patients with postoperative pain.
Topics: Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug E | 1977 |
Comparison of nefopam and pethidine in postoperative pain.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Meperidine; Nefopam; Oxazocines; Pain, Postop | 1977 |
A double-blind comparison of nefopam and placebo in post-operative pain.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hysterectomy; Middle Aged; Nef | 1978 |
Nefopam in postoperative pain.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule | 1979 |
Comparison of the analgesic dose-effect relationships of nefopam and oxycodone in postoperative pain.
Topics: Adult; Aged; Clinical Trials as Topic; Codeine; Dose-Response Relationship, Drug; Double-Blind Metho | 1979 |
Double blind study of nefopam, tilidine or placebo, on postoperative pain relief.
Topics: Adult; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Humans; M | 1979 |
Nefopam and morphine in man.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Morphine; Nefopam; Oxazoci | 1975 |
[Analgesic and respiratory effects of nalbuphine during the immediate postoperative period in thoracotomy].
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Female; Hemodynamics; Humans; Male; Middle Aged | 1990 |
The effect of diclofenac and nefopam on postoperative dental pain.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Diclofenac; Double-B | 1990 |
Postoperative nefopam and diclofenac. Evaluation of their morphine-sparing effect after upper abdominal surgery.
Topics: Abdomen; Adult; Aged; Diclofenac; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; | 1990 |
Double-blind clinical trial of nefopam in comparison with pentazocine in surgical patients.
Topics: Adult; Double-Blind Method; Female; Humans; Male; Middle Aged; Nefopam; Oxazocines; Pain, Postoperat | 1989 |
Assessment of the analgesic efficacy of nefopam hydrochloride after upper abdominal surgery: a study using patient controlled analgesia.
Topics: Abdomen; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; | 1988 |
Nefopam in postoperative pain.
Topics: Adult; Aged; Carbon Dioxide; Female; Humans; Middle Aged; Nefopam; Oxazocines; Pain, Postoperative; | 1985 |
17 other studies available for nefopam and Pain, Postoperative
| Article | Year |
|---|---|
Nefopam prescribing preferences in French hospitals: results of a survey.
Topics: Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Hospitals; Humans; Nefopam; Pain, Postoperative | 2022 |
Changes in hospital consumption of opioid and non-opioid analgesics after colorectal endometriosis surgery.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Colorectal Neoplasms; Colorectal Surgery; Endometriosi | 2023 |
Nefopam hydrochloride loaded microspheres for post-operative pain management: synthesis, physicochemical characterization and in-vivo evaluation.
Topics: Analgesics; Animals; Behavior, Animal; Chemical Phenomena; Chemistry Techniques, Synthetic; Drug Car | 2018 |
Postoperative Pain and Opioid Consumption in the Acute Postoperative Period after Laparoscopic Gastrectomy.
Topics: Analgesics, Opioid; Gastrectomy; Humans; Laparoscopy; Nefopam; Pain, Postoperative; Prospective Stud | 2018 |
[Assessment of practices in postoperative analgesia in caesarean before and after implementation of an information program].
Topics: Acetaminophen; Adult; Analgesia, Obstetrical; Analgesics; Anesthesia, General; Anesthesia, Obstetric | 2013 |
Unilateral permanent loss of vision after nefopam administration.
Topics: Aged; Analgesics, Non-Narcotic; Anesthesia, General; Arthroplasty, Replacement, Knee; Blindness; Fem | 2013 |
Long-term pain vulnerability after surgery in rats: prevention by nefopam, an analgesic with antihyperalgesic properties.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Carrageenan; Chronic Disease; Fentanyl; Hyper | 2009 |
Nefopam after total hip arthroplasty: role in multimodal analgesia.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty | 2013 |
[Nefopam by continuous intravenous injection and adverse drug reactions: which causality assessment?].
Topics: Acute Kidney Injury; Aged; Analgesics, Non-Narcotic; Humans; Hypoproteinemia; Injections, Intravenou | 2007 |
Effective dose of nefopam in 80% of patients (ED80): a study using the continual reassessment method.
Topics: Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Huma | 2007 |
Nefopam and ketoprofen synergy in rodent models of antinociception.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, A | 2008 |
Nefopam reduces thermal hypersensitivity in acute and postoperative pain models in the rat.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Hot Temperature; Hyperalgesia; Male; Morphine | 2001 |
[Ajan for postoperative pain].
Topics: Adult; Aged; Dipyrone; Female; Humans; Hysterectomy; Injections, Intravenous; Middle Aged; Nefopam; | 1977 |
Comparison of nefopam hydrochloride and propoxyphene hydrochloride in the treatment of postoperative pain.
Topics: Adolescent; Adult; Aged; Dextropropoxyphene; Double-Blind Method; Female; Humans; Male; Middle Aged; | 1979 |
[Nefopam in postoperative analgesia. Comparison with meperidine and morphine].
Topics: Adult; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Meperidine; Middle | 1988 |
[Ketoprofen and nefopam in postoperative analgesia after cesarean section].
Topics: Cesarean Section; Female; Humans; Ketoprofen; Nefopam; Oxazocines; Pain, Postoperative; Phenylpropio | 1987 |
The need for analgesic cover after ENT surgery--comparison of nefopam and papaveretum.
Topics: Child; Humans; Injections, Intramuscular; Intraoperative Period; Nefopam; Opium; Otorhinolaryngologi | 1985 |