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nefopam and Neoplasms

nefopam has been researched along with Neoplasms in 9 studies

Nefopam: Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for the relief of acute and chronic pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p26)
nefopam : A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine : A member of the class of benzoxazocines that is 3,4,5,6-tetrahydro-1H-2,5-benzoxazocine substituted by phenyl and methyl groups at positions 1 and 5 respectively.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of nefopam, a novel analgesic agent, was compared to pentazocine in a double blind study in 40 cancer patients with chronic pain."5.04[Analgesia with mild side effects]. ( Schietzel, M, 1977)
"Treatment with meperidine hydrochloride, currently the most widely used medication for controlling amphotericin B-induced shivering, was compared with nefopam hydrochloride, which has been successfully used to treat post-operative shivering."2.68Efficacy of nefopam for the prevention and treatment of amphotericin B-induced shivering. ( Cogliati, A; Conti, G; Dell'Utri, D; Gasparetto, A; Orsi, P; Pelaia, P; Rosa, G, 1997)
"Nefopam is a centrally (but not spinally) acting analgesic with a novel activity profile."1.27Control of cancer pain with analgesics acting in the central nervous system. ( Wörz, R, 1984)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Pasutharnchat, K1
Wichachai, W1
Buachai, R1
Looi, YC1
Audisio, RA1
Wörz, R1
Rosa, G1
Dell'Utri, D1
Conti, G1
Pelaia, P1
Cogliati, A1
Orsi, P1
Gasparetto, A1
Evtiukhin, AI1
Kuznetsova, OIu1
Gorokhov, LV1
Dunaevskiĭ, IV1
Schietzel, M1
de Thibault de Boesinghe, L1
Van Daele, MJ1
Van Severen, G1
Minotti, V1
Patoia, L1
Roila, F1
Basurto, C1
Tonato, M1
Pasqualucci, V1
Maresca, V1
Del Favero, A1

Reviews

2 reviews available for nefopam and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
A review of the literature on post-operative pain in older cancer patients.
    European journal of cancer (Oxford, England : 1990), 2007, Volume: 43, Issue:15

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Nefopam; Neoplas

2007

Trials

6 trials available for nefopam and Neoplasms

ArticleYear
Analgesic efficacy of nefopam for cancer pain: a randomized controlled study.
    F1000Research, 2020, Volume: 9

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Cancer Pain; Double-Blind Method; Female; Humans; Male; Middl

2020
Efficacy of nefopam for the prevention and treatment of amphotericin B-induced shivering.
    Archives of internal medicine, 1997, Jul-28, Volume: 157, Issue:14

    Topics: Adult; Aged; Amphotericin B; Analgesics, Non-Narcotic; Analgesics, Opioid; Antifungal Agents; Antine

1997
[The use of Oxadol in tablet form for the treatment of chronic pain syndrome in late-stage cancer patients].
    Voprosy onkologii, 2000, Volume: 46, Issue:2

    Topics: Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Drug Ther

2000
[Analgesia with mild side effects].
    Fortschritte der Medizin, 1977, Dec-01, Volume: 95, Issue:45

    Topics: Analgesia; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Humans; Nefopam; Neoplasm

1977
Open study of the analgesic effects of nefopam hydrochloride (Acupan) on cancer patients with pain.
    Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:1

    Topics: Clinical Trials as Topic; Humans; Nefopam; Neoplasms; Oxazocines; Pain

1976
Double-blind evaluation of analgesic efficacy of orally administered diclofenac, nefopam, and acetylsalicylic acid (ASA) plus codeine in chronic cancer pain.
    Pain, 1989, Volume: 36, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Aspirin; Chronic Disea

1989

Other Studies

1 other study available for nefopam and Neoplasms

ArticleYear
Control of cancer pain with analgesics acting in the central nervous system.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1984, Volume: 89

    Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Female; Humans; Male; Middle Aged; Morphine; Nefopam

1984