nefopam has been researched along with Neoplasms in 9 studies
Nefopam: Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for the relief of acute and chronic pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p26)
nefopam : A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine : A member of the class of benzoxazocines that is 3,4,5,6-tetrahydro-1H-2,5-benzoxazocine substituted by phenyl and methyl groups at positions 1 and 5 respectively.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of nefopam, a novel analgesic agent, was compared to pentazocine in a double blind study in 40 cancer patients with chronic pain." | 5.04 | [Analgesia with mild side effects]. ( Schietzel, M, 1977) |
| "Treatment with meperidine hydrochloride, currently the most widely used medication for controlling amphotericin B-induced shivering, was compared with nefopam hydrochloride, which has been successfully used to treat post-operative shivering." | 2.68 | Efficacy of nefopam for the prevention and treatment of amphotericin B-induced shivering. ( Cogliati, A; Conti, G; Dell'Utri, D; Gasparetto, A; Orsi, P; Pelaia, P; Rosa, G, 1997) |
| "Nefopam is a centrally (but not spinally) acting analgesic with a novel activity profile." | 1.27 | Control of cancer pain with analgesics acting in the central nervous system. ( Wörz, R, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Pasutharnchat, K | 1 |
| Wichachai, W | 1 |
| Buachai, R | 1 |
| Looi, YC | 1 |
| Audisio, RA | 1 |
| Wörz, R | 1 |
| Rosa, G | 1 |
| Dell'Utri, D | 1 |
| Conti, G | 1 |
| Pelaia, P | 1 |
| Cogliati, A | 1 |
| Orsi, P | 1 |
| Gasparetto, A | 1 |
| Evtiukhin, AI | 1 |
| Kuznetsova, OIu | 1 |
| Gorokhov, LV | 1 |
| Dunaevskiĭ, IV | 1 |
| Schietzel, M | 1 |
| de Thibault de Boesinghe, L | 1 |
| Van Daele, MJ | 1 |
| Van Severen, G | 1 |
| Minotti, V | 1 |
| Patoia, L | 1 |
| Roila, F | 1 |
| Basurto, C | 1 |
| Tonato, M | 1 |
| Pasqualucci, V | 1 |
| Maresca, V | 1 |
| Del Favero, A | 1 |
2 reviews available for nefopam and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
A review of the literature on post-operative pain in older cancer patients.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Nefopam; Neoplas | 2007 |
6 trials available for nefopam and Neoplasms
| Article | Year |
|---|---|
Analgesic efficacy of nefopam for cancer pain: a randomized controlled study.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Cancer Pain; Double-Blind Method; Female; Humans; Male; Middl | 2020 |
Efficacy of nefopam for the prevention and treatment of amphotericin B-induced shivering.
Topics: Adult; Aged; Amphotericin B; Analgesics, Non-Narcotic; Analgesics, Opioid; Antifungal Agents; Antine | 1997 |
[The use of Oxadol in tablet form for the treatment of chronic pain syndrome in late-stage cancer patients].
Topics: Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Drug Ther | 2000 |
[Analgesia with mild side effects].
Topics: Analgesia; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Humans; Nefopam; Neoplasm | 1977 |
Open study of the analgesic effects of nefopam hydrochloride (Acupan) on cancer patients with pain.
Topics: Clinical Trials as Topic; Humans; Nefopam; Neoplasms; Oxazocines; Pain | 1976 |
Double-blind evaluation of analgesic efficacy of orally administered diclofenac, nefopam, and acetylsalicylic acid (ASA) plus codeine in chronic cancer pain.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Aspirin; Chronic Disea | 1989 |
1 other study available for nefopam and Neoplasms
| Article | Year |
|---|---|
Control of cancer pain with analgesics acting in the central nervous system.
Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Female; Humans; Male; Middle Aged; Morphine; Nefopam | 1984 |