nefopam has been researched along with Emesis, Postoperative in 5 studies
Nefopam: Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for the relief of acute and chronic pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p26)
nefopam : A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine : A member of the class of benzoxazocines that is 3,4,5,6-tetrahydro-1H-2,5-benzoxazocine substituted by phenyl and methyl groups at positions 1 and 5 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study comparatively evaluated the effect of patient-controlled analgesia (PCA) regimens using equipotent doses of nefopam or fentanyl during laparoscopic gynecological surgery on postoperative nausea and vomiting (PONV)." | 9.20 | Effect of nefopam- versus fentanyl-based patient-controlled analgesia on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a prospective double-blind randomized controlled trial. ( Jung, E; Kim, SH; Lee, SJ; Oh, CS, 2015) |
| "Nefopam has been considered as a good candidate for inclusion in multimodal analgesia because of its opioid sparing effect, but it can be emetic." | 6.87 | Association of nefopam use with postoperative nausea and vomiting in gynecological patients receiving prophylactic ramosetron: A retrospective study. ( Bahk, JH; Kim, JT; Kim, WH; Lim, YJ; Park, SK; Yoo, S, 2018) |
| "This study comparatively evaluated the effect of patient-controlled analgesia (PCA) regimens using equipotent doses of nefopam or fentanyl during laparoscopic gynecological surgery on postoperative nausea and vomiting (PONV)." | 5.20 | Effect of nefopam- versus fentanyl-based patient-controlled analgesia on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a prospective double-blind randomized controlled trial. ( Jung, E; Kim, SH; Lee, SJ; Oh, CS, 2015) |
| "3-mg/kg bolus of nefopam at the induction of anesthesia followed by a continuous infusion of 0." | 5.17 | Effects of nefopam on early postoperative hyperalgesia after cardiac surgery. ( Branchard, O; Cahana, A; Janvier, G; Jelacic, S; Leproust, S; Picard, W; Richebé, P; Rivat, C, 2013) |
| " The primary outcome was the dosage of fentanyl-nefopam IV-PCA infused over 24 h postoperatively." | 3.11 | Effect of remifentanil on post-operative analgesic consumption in patients undergoing shoulder arthroplasty after interscalene brachial plexus block: a randomized controlled trial. ( Bae, H; Kim, JT; Kim, Y; Lim, YJ; Park, SK; Sakura, S; Yoo, S, 2022) |
| "Nefopam has been considered as a good candidate for inclusion in multimodal analgesia because of its opioid sparing effect, but it can be emetic." | 2.87 | Association of nefopam use with postoperative nausea and vomiting in gynecological patients receiving prophylactic ramosetron: A retrospective study. ( Bahk, JH; Kim, JT; Kim, WH; Lim, YJ; Park, SK; Yoo, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, Y | 1 |
| Bae, H | 1 |
| Yoo, S | 2 |
| Park, SK | 2 |
| Lim, YJ | 2 |
| Sakura, S | 1 |
| Kim, JT | 2 |
| Kim, WH | 1 |
| Bahk, JH | 1 |
| Oh, CS | 1 |
| Jung, E | 1 |
| Lee, SJ | 1 |
| Kim, SH | 1 |
| Richebé, P | 1 |
| Picard, W | 1 |
| Rivat, C | 1 |
| Jelacic, S | 1 |
| Branchard, O | 1 |
| Leproust, S | 1 |
| Cahana, A | 1 |
| Janvier, G | 1 |
| Merle, JC | 1 |
| Vandroux, D | 1 |
| Odin, I | 1 |
| Dupuis, JL | 1 |
| Bougault, A | 1 |
| Mehaddi, Y | 1 |
| Nathan, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial on the Effect and Safety of Intravenous Nefopam/Fentanyl Postoperative Patient-Controlled-Analgesia in Patients Undergoing Laparotomy[NCT02596269] | Phase 2/Phase 3 | 73 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
| Study of the Effects of Nefopam on Hyperalgesia Following Sternotomy in Cardiac Surgery[NCT00413257] | Phase 2/Phase 3 | 90 participants (Actual) | Interventional | 2006-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for nefopam and Emesis, Postoperative
| Article | Year |
|---|---|
Effect of remifentanil on post-operative analgesic consumption in patients undergoing shoulder arthroplasty after interscalene brachial plexus block: a randomized controlled trial.
Topics: Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Shoulder; Brachial Plexus Block; Delirium | 2022 |
Association of nefopam use with postoperative nausea and vomiting in gynecological patients receiving prophylactic ramosetron: A retrospective study.
Topics: Adult; Analgesia, Patient-Controlled; Anesthesia, Obstetrical; Benzimidazoles; Female; Fentanyl; Gyn | 2018 |
Effect of nefopam- versus fentanyl-based patient-controlled analgesia on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a prospective double-blind randomized controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Gyn | 2015 |
Effects of nefopam on early postoperative hyperalgesia after cardiac surgery.
Topics: Aged; Analgesics, Non-Narcotic; Anesthesia; Cardiac Surgical Procedures; Coronary Artery Bypass; Dou | 2013 |
[Analgesic effect of continuous intravenous nefopam after urological surgery].
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Meth | 2005 |