nefopam has been researched along with Critical Illness in 2 studies
Nefopam: Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for the relief of acute and chronic pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p26)
nefopam : A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine : A member of the class of benzoxazocines that is 3,4,5,6-tetrahydro-1H-2,5-benzoxazocine substituted by phenyl and methyl groups at positions 1 and 5 respectively.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A single slow infusion of nefopam is effective in critically ill patients who have moderate pain." | 5.15 | Analgesic efficacy and haemodynamic effects of nefopam in critically ill patients. ( Chanques, G; Cissé, M; Constantin, JM; Jaber, S; Jung, B; Lefrant, JY; Ramillon, N; Sebbane, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Payen, JF | 1 |
| Genty, C | 1 |
| Mimoz, O | 1 |
| Mantz, J | 1 |
| Bosson, JL | 1 |
| Chanques, G | 2 |
| Sebbane, M | 1 |
| Constantin, JM | 1 |
| Ramillon, N | 1 |
| Jung, B | 1 |
| Cissé, M | 1 |
| Lefrant, JY | 1 |
| Jaber, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Patients: Randomized Double-blind Controlled Study[NCT05071352] | Phase 3 | 60 participants (Anticipated) | Interventional | 2021-10-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for nefopam and Critical Illness
| Article | Year |
|---|---|
Analgesic efficacy and haemodynamic effects of nefopam in critically ill patients.
Topics: Analgesics, Non-Narcotic; Cardiac Output; Critical Care; Critical Illness; Female; Heart Rate; Hemod | 2011 |
1 other study available for nefopam and Critical Illness
| Article | Year |
|---|---|
Prescribing nonopioids in mechanically ventilated critically ill patients.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Chi-Square Distribution; C | 2013 |