Page last updated: 2024-10-31

nefopam and Chemical Dependence

nefopam has been researched along with Chemical Dependence in 2 studies

Nefopam: Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for the relief of acute and chronic pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p26)
nefopam : A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine : A member of the class of benzoxazocines that is 3,4,5,6-tetrahydro-1H-2,5-benzoxazocine substituted by phenyl and methyl groups at positions 1 and 5 respectively.

Research Excerpts

ExcerptRelevanceReference
"Nefopam is a non-opioid analgesic reported to have some stimulant properties."1.27A comparative assay of nefopam, morphine and d-amphetamine. ( Jasinski, DR; Preston, KL, 1987)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Villier, C1
Mallaret, MP1
Jasinski, DR1
Preston, KL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-blind Placebo-controlled Evaluation of Ropivacaine Efficacy by Local Per and Post Hepatectomy Infiltrations for Adult Pain Management[NCT01194843]85 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for nefopam and Chemical Dependence

ArticleYear
Nefopam abuse.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:10

    Topics: Adult; Analgesics, Non-Narcotic; Female; Humans; Injections, Intramuscular; Injections, Intravenous;

2002
A comparative assay of nefopam, morphine and d-amphetamine.
    Psychopharmacology, 1987, Volume: 91, Issue:3

    Topics: Behavior; Dextroamphetamine; Dose-Response Relationship, Drug; Humans; Male; Morphine; Nefopam; Oxaz

1987