nefopam has been researched along with Adverse Drug Event in 3 studies
Nefopam: Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for the relief of acute and chronic pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p26)
nefopam : A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine : A member of the class of benzoxazocines that is 3,4,5,6-tetrahydro-1H-2,5-benzoxazocine substituted by phenyl and methyl groups at positions 1 and 5 respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nefopam is a non-opioid, non-nonsteroidal anti-imflammatory drug, analgesic drug that inhibits the reuptake of serotonin, norepinephrine, and dopamine." | 3.11 | Postoperative analgesia of intraoperative nefopam in patients undergoing anterior cervical spine surgery: A prospective randomized controlled trial. ( Homprasert, C; Nitising, A; Pantubtim, C; Raksakietisak, M; Rushatamukayanunt, P; Sawasdiwipachai, P; Wilaiwan, K, 2022) |
| "Postoperative pain was treated successfully in both groups." | 2.78 | Ondansetron does not attenuate the analgesic efficacy of nefopam. ( Chen, J; Chen, Y; Li, MG; Lu, KZ; Shen, H; Tian, GP, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 2 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Raksakietisak, M | 1 |
| Rushatamukayanunt, P | 1 |
| Wilaiwan, K | 1 |
| Homprasert, C | 1 |
| Nitising, A | 1 |
| Sawasdiwipachai, P | 1 |
| Pantubtim, C | 1 |
| Lu, KZ | 1 |
| Shen, H | 1 |
| Li, MG | 1 |
| Tian, GP | 1 |
| Chen, J | 1 |
2 trials available for nefopam and Adverse Drug Event
| Article | Year |
|---|---|
Postoperative analgesia of intraoperative nefopam in patients undergoing anterior cervical spine surgery: A prospective randomized controlled trial.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Cervical Vertebrae; Double-Blind Method; Dr | 2022 |
Ondansetron does not attenuate the analgesic efficacy of nefopam.
Topics: Adult; Aged; Analgesics; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; | 2013 |
1 other study available for nefopam and Adverse Drug Event
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |