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nefazodone and Sleep Initiation and Maintenance Disorders

nefazodone has been researched along with Sleep Initiation and Maintenance Disorders in 12 studies

nefazodone: may be useful as an opiate adjunct

Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.

Research Excerpts

ExcerptRelevanceReference
"This paper reports combined results of three identical, multisite, randomized, double-blind, 8-week, acute-phase trials comparing nefazodone (n = 64) with fluoxetine (n = 61) in outpatients with nonpsychotic major depressive disorder and insomnia."9.08Comparative effects of nefazodone and fluoxetine on sleep in outpatients with major depressive disorder. ( Albala, BJ; Armitage, R; Erman, MK; Fleming, JB; Gillin, JC; Kaplita, SB; McQuade, RD; Moldofsky, H; Montplaisir, J; Rush, AJ; Vogel, GW; Winokur, A; Yonkers, KA, 1998)
"One hundred sixty-six patients suffering from major depressive disorders were treated for 8 weeks with nefazodone in an open study in dosage ranges from 200 to 600 mg."5.08Nefazodone in major depression: adjunctive benzodiazepine therapy and tolerability. ( Case, WG; DeMartinis, N; Garcia España, FG; Greenblatt, DJ; Mandos, LA; Rickels, K; Schweizer, E, 1998)
"This paper reports combined results of three identical, multisite, randomized, double-blind, 8-week, acute-phase trials comparing nefazodone (n = 64) with fluoxetine (n = 61) in outpatients with nonpsychotic major depressive disorder and insomnia."5.08Comparative effects of nefazodone and fluoxetine on sleep in outpatients with major depressive disorder. ( Albala, BJ; Armitage, R; Erman, MK; Fleming, JB; Gillin, JC; Kaplita, SB; McQuade, RD; Moldofsky, H; Montplaisir, J; Rush, AJ; Vogel, GW; Winokur, A; Yonkers, KA, 1998)
"Continuous and categorical insomnia outcomes, derived from standard clinician- and self-rated assessments, were compared."2.70Differential effects of nefazodone and cognitive behavioral analysis system of psychotherapy on insomnia associated with chronic forms of major depression. ( Borian, FE; Dunner, DL; Friedman, ES; Keller, MB; Klein, DN; Kornstein, SG; Manber, R; Markowitz, JC; Ninan, PT; Rush, AJ; Schatzberg, AF; Thase, ME; Trivedi, MH, 2002)
"Nefazodone was well tolerated, and no significant changes in sexual function were reported."2.69Open trial of nefazodone for combat-related posttraumatic stress disorder. ( Beckham, JC; Davidson, JR; Feldman, ME; Hertzberg, MA; Moore, SD, 1998)
" The rates for individual side effects with the serotonin selective reuptake inhibitors, nefazodone, and venlafaxine are presented and compared with the adverse event experience for mirtazapine."2.40Safety and tolerability of the new antidepressants. ( Nelson, JC, 1997)
"Therefore, early relief of insomnia in a depressed patient, in addition to alleviating other symptoms, may increase adherence to treatment and increase daytime performance and overall functioning, while complete relief of insomnia may improve prognosis."2.40Antidepressant treatment of the depressed patient with insomnia. ( Thase, ME, 1999)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (75.00)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brownlow, JA1
Harb, GC1
Ross, RJ1
Wiegand, MH1
Galanakis, P1
Schreiner, R1
Nelson, JC1
Rickels, K1
Schweizer, E1
Case, WG1
DeMartinis, N1
Greenblatt, DJ1
Mandos, LA1
Garcia España, FG1
Rush, AJ2
Armitage, R1
Gillin, JC1
Yonkers, KA1
Winokur, A1
Moldofsky, H1
Vogel, GW1
Kaplita, SB1
Fleming, JB1
Montplaisir, J1
Erman, MK1
Albala, BJ1
McQuade, RD1
Hertzberg, MA1
Feldman, ME1
Beckham, JC1
Moore, SD1
Davidson, JR1
Scharf, MB1
McDannold, M1
Zaretsky, N1
Spinner, O1
Stover, R1
Berkowitz, DV1
Conrad, C1
Thase, ME2
Manber, R1
Kornstein, SG1
Klein, DN1
Markowitz, JC1
Ninan, PT1
Friedman, ES1
Dunner, DL1
Schatzberg, AF1
Borian, FE1
Trivedi, MH1
Keller, MB1

Reviews

3 reviews available for nefazodone and Sleep Initiation and Maintenance Disorders

ArticleYear
Treatment of Sleep Disturbances in Post-Traumatic Stress Disorder: A Review of the Literature.
    Current psychiatry reports, 2015, Volume: 17, Issue:6

    Topics: Antipsychotic Agents; Cognitive Behavioral Therapy; Dreams; Eye Movement Desensitization Reprocessin

2015
Safety and tolerability of the new antidepressants.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 6

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Depressiv

1997
Antidepressant treatment of the depressed patient with insomnia.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 17

    Topics: Antidepressive Agents, Tricyclic; Comorbidity; Cyclohexanols; Depressive Disorder; Fluoxetine; Human

1999

Trials

6 trials available for nefazodone and Sleep Initiation and Maintenance Disorders

ArticleYear
Nefazodone in primary insomnia: an open pilot study.
    Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:7

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Female; Humans; Male; Middle Aged; Patient Dr

2004
Nefazodone in major depression: adjunctive benzodiazepine therapy and tolerability.
    Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:2

    Topics: Adult; Aged; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Benzodiazepines; Depress

1998
Comparative effects of nefazodone and fluoxetine on sleep in outpatients with major depressive disorder.
    Biological psychiatry, 1998, Jul-01, Volume: 44, Issue:1

    Topics: Adult; Ambulatory Care; Antidepressive Agents, Second-Generation; Circadian Rhythm; Comorbidity; Dep

1998
Open trial of nefazodone for combat-related posttraumatic stress disorder.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:9

    Topics: Adult; Ambulatory Care; Anger; Antidepressive Agents, Second-Generation; Combat Disorders; Depressiv

1998
Evaluation of sleep architecture and cyclic alternating pattern rates in depressed insomniac patients treated with nefazodone hydrochloride.
    American journal of therapeutics, 1999, Volume: 6, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Depression; Female; Humans; Male; Periodicity; Pipe

1999
Differential effects of nefazodone and cognitive behavioral analysis system of psychotherapy on insomnia associated with chronic forms of major depression.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Chronic Disease; Cognitive Behavioral Therapy; Comb

2002

Other Studies

3 other studies available for nefazodone and Sleep Initiation and Maintenance Disorders

ArticleYear
[Nefazodone: a new antidepressive agent. Advantages of a dual working principle].
    Der Nervenarzt, 1997, Volume: 68, Issue:7 Suppl Ne

    Topics: Antidepressive Agents, Second-Generation; Depressive Disorder; Humans; Piperazines; Sleep; Sleep Ini

1997
[Sleep-profile of a 72-year-old depressive female patient. Depression and sleep disorders. Significance--causes--treatment].
    Fortschritte der Neurologie-Psychiatrie, 1998, Volume: 66, Issue:5 Suppl De

    Topics: Aged; Antidepressive Agents, Second-Generation; Depression; Female; Humans; Piperazines; Sleep Initi

1998
[Depression and sleep disorders. Progress in antidepressive therapy with nefazodone].
    Der Nervenarzt, 1998, Volume: 69, Issue:6 Suppl Ei

    Topics: Antidepressive Agents, Second-Generation; Depression; Humans; Piperazines; Sleep Initiation and Main

1998