Page last updated: 2024-10-31

nefazodone and Serotonin Syndrome

nefazodone has been researched along with Serotonin Syndrome in 3 studies

nefazodone: may be useful as an opiate adjunct

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
"The serotonin syndrome is characterized by a constellation of symptoms that include mental status changes, agitation, myoclonus, hyperreflexia, sweating, shivering, tremor, diarrhoea, lack of coordination, and fever."1.30Antidepressants and the serotonin syndrome in general practice. ( Dunn, NR; Mackay, FJ; Mann, RD, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smith, DL1
Wenegrat, BG1
Mackay, FJ1
Dunn, NR1
Mann, RD1
Margolese, HC1
Chouinard, G1

Other Studies

3 other studies available for nefazodone and Serotonin Syndrome

ArticleYear
A case report of serotonin syndrome associated with combined nefazodone and fluoxetine.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Bipolar Disorder; Drug Therapy, Combination; Fluoxetine; H

2000
Antidepressants and the serotonin syndrome in general practice.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 1999, Volume: 49, Issue:448

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Depressive Disorder; Family Pract

1999
Serotonin syndrome from addition of low-dose trazodone to nefazodone.
    The American journal of psychiatry, 2000, Volume: 157, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Drug Interactions; Drug Therapy, Combination; Female; Huma

2000