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nefazodone and Premenstrual Syndrome

nefazodone has been researched along with Premenstrual Syndrome in 7 studies

nefazodone: may be useful as an opiate adjunct

Premenstrual Syndrome: A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses.

Research Excerpts

ExcerptRelevanceReference
"Nefazodone, a new phenylpiperazine antidepressant agent with serotonin type 2 antagonism and serotonin reuptake inhibition, was evaluated in two patient groups to determine its effectiveness in reducing the symptoms of premenstrual syndrome (PMS)."9.07Nefazodone in the treatment of premenstrual syndrome: a preliminary study. ( Denis, A; Freeman, EW; Pfeifer, S; Rickels, K; Sondheimer, SJ; Weil, S, 1994)
"Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism."5.29Probable nefazodone-induced mania in a patient with unreported bipolar disorder. ( Blaisdell, GD; Jermain, DM; Zaphiris, HA, 1996)
"Nefazodone, a new phenylpiperazine antidepressant agent with serotonin type 2 antagonism and serotonin reuptake inhibition, was evaluated in two patient groups to determine its effectiveness in reducing the symptoms of premenstrual syndrome (PMS)."5.07Nefazodone in the treatment of premenstrual syndrome: a preliminary study. ( Denis, A; Freeman, EW; Pfeifer, S; Rickels, K; Sondheimer, SJ; Weil, S, 1994)
"Lifetime psychiatric illness is also common in women with PMDD, and although mood disorders predominate, past histories of anxiety disorders are also common, further suggesting an association between PMDD and anxiety disorders."2.40Anxiety symptoms and anxiety disorders: how are they related to premenstrual disorders? ( Yonkers, KA, 1997)
" It offers advantages over daily dosing throughout the menstrual cycle, such as reduced incidence and severity of side-effects, and avoids the stigma that may accompany the continuous use of psychopharmacological treatment, with the advantage that compliance may be improved."1.31Intermittent, luteal phase nefazodone treatment of premenstrual dysphoric disorder. ( Finkel, B; Katz, S; Kodesh, A; Lerner, AG; Sigal, M, 2001)
"Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism."1.29Probable nefazodone-induced mania in a patient with unreported bipolar disorder. ( Blaisdell, GD; Jermain, DM; Zaphiris, HA, 1996)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (57.14)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Freeman, EW1
Rickels, K1
Sondheimer, SJ1
Denis, A1
Pfeifer, S1
Weil, S1
Zaphiris, HA1
Blaisdell, GD1
Jermain, DM1
Yonkers, KA1
Fogelson, DL1
Kodesh, A1
Katz, S1
Lerner, AG1
Finkel, B1
Sigal, M1
Landén, M1
Eriksson, O1
Sundblad, C1
Andersch, B1
Naessén, T1
Eriksson, E1
Miller, MN1
Miller, BE1
Chinouth, R1
Coyle, BR1
Brown, GR1

Reviews

1 review available for nefazodone and Premenstrual Syndrome

ArticleYear
Anxiety symptoms and anxiety disorders: how are they related to premenstrual disorders?
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 3

    Topics: 1-Naphthylamine; Adult; Age of Onset; Anxiety; Anxiety Disorders; Buspirone; Carbon Dioxide; Comorbi

1997

Trials

2 trials available for nefazodone and Premenstrual Syndrome

ArticleYear
Nefazodone in the treatment of premenstrual syndrome: a preliminary study.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Antidepressive Agents; Drug Administration Schedule; Female; Humans; Piperazines;

1994
Compounds with affinity for serotonergic receptors in the treatment of premenstrual dysphoria: a comparison of buspirone, nefazodone and placebo.
    Psychopharmacology, 2001, Volume: 155, Issue:3

    Topics: Adult; Buspirone; Double-Blind Method; Female; Humans; Piperazines; Premenstrual Syndrome; Psychiatr

2001

Other Studies

4 other studies available for nefazodone and Premenstrual Syndrome

ArticleYear
Probable nefazodone-induced mania in a patient with unreported bipolar disorder.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1996, Volume: 8, Issue:4

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depres

1996
Nefazodone- and/or sodium tetradecyl sulfate-associated leukopenia, fever, and shaking chills in a patient with premenstrual dysphoric disorder.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Female; Fever; Humans; Leukopenia; Middle Aged; Piperazine

1997
Intermittent, luteal phase nefazodone treatment of premenstrual dysphoric disorder.
    Journal of psychopharmacology (Oxford, England), 2001, Volume: 15, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Female; Humans; Luteal Phase; Piperazines; Premenst

2001
Increased premenstrual dosing of nefazodone relieves premenstrual magnification of depression.
    Depression and anxiety, 2002, Volume: 15, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Drug; Female; Humans; P

2002