nefazodone has been researched along with Liver Dysfunction in 4 studies
nefazodone: may be useful as an opiate adjunct
| Excerpt | Relevance | Reference |
|---|---|---|
| " In healthy volunteers, nefazodone was rapidly absorbed after which the plasma concentrations declined with an apparent elimination half-life ranging from 2." | 2.67 | Influence of hepatic impairment on the pharmacokinetics of nefazodone and two of its metabolites after single and multiple oral doses. ( Bernard, N; Cuisinaud, G; Ferry, N; Rougier, P; Sassard, J; Trepo, C, 1994) |
| "Nefazodone is a new antidepressant drug, chemically unrelated to the tricyclic, tetracyclic or selective serotonin uptake inhibitors." | 2.40 | Clinical pharmacokinetics of nefazodone. ( Barbhaiya, RH; Greene, DS, 1997) |
| "To estimate the cumulative incidence of hepatic adverse reactions associated with antidepressants, we used cases of hepatic damage collected via spontaneous reporting and included in the Spanish Pharmacovigilance System database; for exposure, we have used data from drug sales to the Spanish National Health System." | 1.31 | Hepatotoxicity associated with the new antidepressants. ( Carvajal García-Pando, A; García del Pozo, J; Lucena, MI; Rueda de Castro, AM; Sánchez, AS; Velasco, MA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dubarek, W | 1 |
| Kucia, K | 1 |
| Ferry, N | 1 |
| Bernard, N | 1 |
| Cuisinaud, G | 1 |
| Rougier, P | 1 |
| Trepo, C | 1 |
| Sassard, J | 1 |
| Greene, DS | 1 |
| Barbhaiya, RH | 1 |
| Carvajal García-Pando, A | 1 |
| García del Pozo, J | 1 |
| Sánchez, AS | 1 |
| Velasco, MA | 1 |
| Rueda de Castro, AM | 1 |
| Lucena, MI | 1 |
2 reviews available for nefazodone and Liver Dysfunction
| Article | Year |
|---|---|
[Applications and safety of modern antidepressants in patients with liver diseases].
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Cycloprop | 2007 |
Clinical pharmacokinetics of nefazodone.
Topics: Adult; Age Factors; Aged; Analgesics; Antidepressive Agents, Second-Generation; Depressive Disorder; | 1997 |
1 trial available for nefazodone and Liver Dysfunction
| Article | Year |
|---|---|
Influence of hepatic impairment on the pharmacokinetics of nefazodone and two of its metabolites after single and multiple oral doses.
Topics: Adolescent; Adult; Antidepressive Agents; Female; Humans; Liver Diseases; Male; Middle Aged; Piperaz | 1994 |
1 other study available for nefazodone and Liver Dysfunction
| Article | Year |
|---|---|
Hepatotoxicity associated with the new antidepressants.
Topics: Adult; Aged; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Depressive Disorder; Dru | 2002 |