nefazodone has been researched along with Combat Disorders in 10 studies
nefazodone: may be useful as an opiate adjunct
Combat Disorders: Neurotic reactions to unusual, severe, or overwhelming military stress.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nefazodone is a unique serotonergic antidepressant that acts as both a presynaptic serotonin reuptake inhibitor and a postsynaptic 5-hydroxytryptamine 2A receptor antagonist." | 2.71 | A placebo-controlled study of nefazodone for the treatment of chronic posttraumatic stress disorder: a preliminary study. ( Ambrose, S; Bartolucci, A; Davis, LL; English, B; Farley, J; Jewell, ME; Petty, F, 2004) |
| "Overall PTSD symptoms as measured by the Clinician-Administered PTSD Scale (CAPS) showed a modest but statistically significant decrease with nefazodone treatment." | 2.70 | Open trial of nefazodone for combat veterans with posttraumatic stress disorder. ( Fichtner, CG; Garfield, DA; Leveroni, C; Mahableshwarkar, A, 2001) |
| "Nefazodone was well tolerated, and no significant changes in sexual function were reported." | 2.69 | Open trial of nefazodone for combat-related posttraumatic stress disorder. ( Beckham, JC; Davidson, JR; Feldman, ME; Hertzberg, MA; Moore, SD, 1998) |
| "A subgroup of PTSD patients received either fluoxetine or placebo in a clinical trial, and a significant SPAN score improvement was observed on fluoxetine." | 2.69 | Derivation of the SPAN, a brief diagnostic screening test for post-traumatic stress disorder. ( Churchill, E; Davidson, JR; Meltzer-Brody, S, 1999) |
| "Nefazodone treatment was well tolerated by this patient population, with only four patients discontinuing because of adverse effects." | 2.69 | Nefazodone treatment for chronic posttraumatic stress disorder: an open trial. ( Davis, LL; Kramer, GL; Murray, J; Nugent, AL; Petty, F, 2000) |
| "Posttraumatic stress disorder (PTSD) is a highly prevalent and often chronic disorder among combat veterans, persisting in as many as 15% of Vietnam veterans for at least 20 years." | 2.69 | Nefazodone in patients with treatment-refractory posttraumatic stress disorder. ( Chentsova-Dutton, YE; Ellenor, GL; Gillin, JC; Kline, NA; Kodsi, AB; Smith-Vaniz, A; Zisook, S, 2000) |
| "Nefazodone was well tolerated and no significant changes in sexual function were reported." | 1.31 | Three- to four-year follow-up to an open trial of nefazodone for combat-related posttraumatic stress disorder. ( Beckham, JC; Davidson, JR; Feldman, ME; Hertzberg, MA; Moore, SD, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 7 (70.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hertzberg, MA | 2 |
| Feldman, ME | 2 |
| Beckham, JC | 2 |
| Moore, SD | 2 |
| Davidson, JR | 3 |
| Davis, LL | 2 |
| Jewell, ME | 1 |
| Ambrose, S | 1 |
| Farley, J | 1 |
| English, B | 1 |
| Bartolucci, A | 1 |
| Petty, F | 2 |
| Martényi, F | 1 |
| Mellman, TA | 1 |
| David, D | 1 |
| Barza, L | 1 |
| Meltzer-Brody, S | 1 |
| Churchill, E | 1 |
| Nugent, AL | 1 |
| Murray, J | 1 |
| Kramer, GL | 1 |
| Zisook, S | 2 |
| Chentsova-Dutton, YE | 1 |
| Smith-Vaniz, A | 2 |
| Kline, NA | 1 |
| Ellenor, GL | 1 |
| Kodsi, AB | 1 |
| Gillin, JC | 2 |
| Garfield, DA | 1 |
| Fichtner, CG | 1 |
| Leveroni, C | 1 |
| Mahableshwarkar, A | 1 |
| Schnierow, B | 1 |
| Rapaport, MH | 1 |
| Kelsoe, J | 1 |
| Raimo, E | 1 |
| Marler, MR | 1 |
| Goyette, LM | 1 |
| Stein, MB | 1 |
1 review available for nefazodone and Combat Disorders
| Article | Year |
|---|---|
[Three paradigms in the treatment of posttraumatic stress disorder].
Topics: Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Benzodiazepines; Combat Disorders; Co | 2005 |
8 trials available for nefazodone and Combat Disorders
| Article | Year |
|---|---|
A placebo-controlled study of nefazodone for the treatment of chronic posttraumatic stress disorder: a preliminary study.
Topics: Adult; Aged; Analysis of Variance; Combat Disorders; Double-Blind Method; Female; Humans; Male; Midd | 2004 |
Open trial of nefazodone for combat-related posttraumatic stress disorder.
Topics: Adult; Ambulatory Care; Anger; Antidepressive Agents, Second-Generation; Combat Disorders; Depressiv | 1998 |
Nefazodone treatment and dream reports in chronic PTSD.
Topics: Aged; Antidepressive Agents, Second-Generation; Chronic Disease; Combat Disorders; Dreams; Female; H | 1999 |
Derivation of the SPAN, a brief diagnostic screening test for post-traumatic stress disorder.
Topics: Adult; Antidepressive Agents; Cohort Studies; Combat Disorders; Disasters; Female; Fluoxetine; Fluvo | 1999 |
Nefazodone treatment for chronic posttraumatic stress disorder: an open trial.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Chronic Disease; Combat Disorders; Female; Hu | 2000 |
Nefazodone in patients with treatment-refractory posttraumatic stress disorder.
Topics: Ambulatory Care; Antidepressive Agents, Second-Generation; Chronic Disease; Circadian Rhythm; Combat | 2000 |
Open trial of nefazodone for combat veterans with posttraumatic stress disorder.
Topics: Adult; Antidepressive Agents, Second-Generation; Combat Disorders; Drug Administration Schedule; Hum | 2001 |
An open-label, 12-week clinical and sleep EEG study of nefazodone in chronic combat-related posttraumatic stress disorder.
Topics: Arousal; Combat Disorders; Depressive Disorder, Major; Dreams; Electroencephalography; Humans; Male; | 2001 |
1 other study available for nefazodone and Combat Disorders
| Article | Year |
|---|---|
Three- to four-year follow-up to an open trial of nefazodone for combat-related posttraumatic stress disorder.
Topics: Adult; Anger; Antidepressive Agents, Second-Generation; Chronic Disease; Clinical Trials as Topic; C | 2002 |