nefazodone has been researched along with Bipolar Disorder in 14 studies
nefazodone: may be useful as an opiate adjunct
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism." | 5.29 | Probable nefazodone-induced mania in a patient with unreported bipolar disorder. ( Blaisdell, GD; Jermain, DM; Zaphiris, HA, 1996) |
| "Thirteen DSM-IV pure depressed-phase nonpsychotic bipolar outpatients received an open-label 8-week pilot trial of flexibly dosed nefazodone (mean±SD peak dose=462." | 2.78 | A preliminary open trial of nefazodone added to mood stabilizers for bipolar depression. ( Goldberg, JF, 2013) |
| " Assessments included Clinical Global Impression Scales, Hamilton Rating Scales for Depression and Anxiety, Montgomery-Asberg Depression Rating Scale and the Patient Global Assessment Scale, in addition to a review of reported adverse events, vital sign measurements, electrocardiograms and clinical laboratory tests." | 2.70 | A randomized, double-blind controlled comparison of nefazodone and paroxetine in the treatment of depression: safety, tolerability and efficacy in continuation phase treatment. ( Baldwin, DS; Hawley, CJ; Mellors, K, 2001) |
| "Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism." | 1.29 | Probable nefazodone-induced mania in a patient with unreported bipolar disorder. ( Blaisdell, GD; Jermain, DM; Zaphiris, HA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (64.29) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldberg, JF | 1 |
| Grunze, H | 1 |
| Marcuse, A | 1 |
| Schärer, LO | 1 |
| Born, C | 1 |
| Walden, J | 1 |
| Jeffries, JJ | 1 |
| al-Jeshi, A | 1 |
| Worthington, JJ | 1 |
| Pollack, MH | 1 |
| Ashton, AK | 1 |
| Wolin, RE | 1 |
| Shammi, C | 1 |
| Zaphiris, HA | 1 |
| Blaisdell, GD | 1 |
| Jermain, DM | 1 |
| Dubin, H | 1 |
| Spier, S | 1 |
| Giannandrea, P | 1 |
| Brazelton, T | 1 |
| Blanc, PD | 1 |
| Olson, KR | 1 |
| El-Mallakh, RS | 1 |
| Mosberian, P | 1 |
| Leung, M | 1 |
| Hollander, Y | 1 |
| Remick, RA | 1 |
| Smith, DL | 1 |
| Wenegrat, BG | 1 |
| MacDonald, J | 1 |
| Rawlins, S | 1 |
| Baldwin, DS | 1 |
| Hawley, CJ | 1 |
| Mellors, K | 1 |
4 trials available for nefazodone and Bipolar Disorder
| Article | Year |
|---|---|
A preliminary open trial of nefazodone added to mood stabilizers for bipolar depression.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Bipolar Disorder; Drug | 2013 |
Nefazodone in psychotic unipolar and bipolar depression: a retrospective chart analysis and open prospective study on its efficacy and safety versus combined treatment with amitriptyline and haloperidol.
Topics: Adult; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; An | 2002 |
Rapid fade of antidepressant effect of nefazodone in bipolar depression.
Topics: Adult; Antidepressive Agents, Second-Generation; Bipolar Disorder; Drug Administration Schedule; Fem | 1999 |
A randomized, double-blind controlled comparison of nefazodone and paroxetine in the treatment of depression: safety, tolerability and efficacy in continuation phase treatment.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Long | 2001 |
10 other studies available for nefazodone and Bipolar Disorder
| Article | Year |
|---|---|
Nefazodone-induced mania.
Topics: Antidepressive Agents; Bipolar Disorder; Humans; Male; Middle Aged; Piperazines; Triazoles | 1995 |
Treatment of dysphoric mania with nefazodone.
Topics: Adult; Antidepressive Agents, Second-Generation; Bipolar Disorder; Drug Therapy, Combination; Female | 1996 |
Nefazodone-induced carbamazepine toxicity.
Topics: Adult; Bipolar Disorder; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; | 1996 |
Antidepressant-induced mania.
Topics: Antidepressive Agents, Second-Generation; Bipolar Disorder; Depressive Disorder; Humans; Male; Middl | 1995 |
Probable nefazodone-induced mania in a patient with unreported bipolar disorder.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depres | 1996 |
Nefazodone-induced mania.
Topics: Antidepressive Agents, Second-Generation; Bipolar Disorder; Depressive Disorder; Female; Humans; Mid | 1997 |
Toxic effects of nefazodone.
Topics: Adult; Antidepressive Agents, Second-Generation; Antimanic Agents; Bipolar Disorder; Female; Humans; | 1997 |
Nefazodone-induced visual disturbances.
Topics: Adult; Antidepressive Agents, Second-Generation; Bipolar Disorder; Humans; Male; Piperazines; Triazo | 1999 |
A case report of serotonin syndrome associated with combined nefazodone and fluoxetine.
Topics: Antidepressive Agents, Second-Generation; Bipolar Disorder; Drug Therapy, Combination; Fluoxetine; H | 2000 |
Neurtropenia due to nefazodone, interaction or coincidence?
Topics: Adult; Antidepressive Agents, Second-Generation; Bipolar Disorder; Drug Interactions; Drug Therapy, | 2000 |