nefazodone has been researched along with Alcoholism in 6 studies
nefazodone: may be useful as an opiate adjunct
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thus, nefazodone therapy was associated with improvement in mood/anxiety and alcohol use, which seem to be independent of each other in this patient sample." | 5.10 | Open-label nefazodone in patients with a major depressive episode and alcohol dependence. ( Bobadilla, L; Brown, ES; Dhillon, H; Frol, A; Nejtek, VA; Perantie, D, 2003) |
| " This double-blind study tested the efficacy of nefazodone versus placebo for the treatment of depression in actively drinking alcohol-dependent patients who were also participating in weekly group treatment for alcoholism." | 5.09 | Nefazodone treatment of major depression in alcohol-dependent patients: a double-blind, placebo-controlled trial. ( Blume, AW; Cowley, DS; Jaffe, C; Kingsley, E; Pages, KP; Ries, RK; Roy-Byrne, PP; Russo, JE, 2000) |
| "Nefazodone might even increase the risk of consuming a larger amount of ethanol per relapse in a subset of patients." | 2.71 | Combination treatment with nefazodone and cognitive-behavioral therapy for relapse prevention in alcohol-dependent men: a randomized controlled study. ( Anghelescu, I; Hautzinger, M; Lörch, B; Müller, MJ; Scheurich, A; Schläfke, D; Singer, P; Sittinger, H; Szegedi, A; Wetzel, H; Wobrock, T, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, ES | 1 |
| Bobadilla, L | 1 |
| Nejtek, VA | 1 |
| Perantie, D | 1 |
| Dhillon, H | 1 |
| Frol, A | 1 |
| Hernandez-Avila, CA | 1 |
| Modesto-Lowe, V | 2 |
| Feinn, R | 1 |
| Kranzler, HR | 2 |
| Hautzinger, M | 2 |
| Wetzel, H | 2 |
| Szegedi, A | 2 |
| Scheurich, A | 2 |
| Lörch, B | 2 |
| Singer, P | 2 |
| Schläfke, D | 2 |
| Sittinger, H | 2 |
| Wobrock, T | 2 |
| Müller, MJ | 2 |
| Anghelescu, I | 2 |
| Van Kirk, J | 1 |
| Roy-Byrne, PP | 1 |
| Pages, KP | 1 |
| Russo, JE | 1 |
| Jaffe, C | 1 |
| Blume, AW | 1 |
| Kingsley, E | 1 |
| Cowley, DS | 1 |
| Ries, RK | 1 |
6 trials available for nefazodone and Alcoholism
| Article | Year |
|---|---|
Open-label nefazodone in patients with a major depressive episode and alcohol dependence.
Topics: Adult; Affect; Alcoholism; Antidepressive Agents, Second-Generation; Anxiety; Depressive Disorder; D | 2003 |
Nefazodone treatment of comorbid alcohol dependence and major depression.
Topics: Adult; Alcoholism; Analysis of Variance; Chi-Square Distribution; Depressive Disorder, Major; Diagno | 2004 |
[Combination treatment with SSRI and cognitive behavior therapy for relapse prevention of alcohol-dependent men. Results of a randomized, controlled multicenter therapeutic study].
Topics: Adult; Alcoholism; Cognitive Behavioral Therapy; Combined Modality Therapy; Disease-Free Survival; G | 2005 |
Combination treatment with nefazodone and cognitive-behavioral therapy for relapse prevention in alcohol-dependent men: a randomized controlled study.
Topics: Adult; Alcoholism; Cognitive Behavioral Therapy; Combined Modality Therapy; Counseling; Diagnosis, C | 2004 |
Naltrexone vs. nefazodone for treatment of alcohol dependence. A placebo-controlled trial.
Topics: Adult; Alcoholism; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Drug; Doubl | 2000 |
Nefazodone treatment of major depression in alcohol-dependent patients: a double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Alcoholism; Antidepressive Agents, Second-Generation; Combined Modality Therapy; | 2000 |