nefazodone has been researched along with Acute Post-Traumatic Stress Disorder in 14 studies
nefazodone: may be useful as an opiate adjunct
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nefazodone treatment led to a significant decrease in PTSD and depressive symptoms (p <." | 2.71 | The effect of nefazodone on subjective and objective sleep quality in posttraumatic stress disorder. ( Lenoci, M; Leykin, Y; Maglione, ML; Marmar, CR; Metzler, TJ; Neylan, TC; Rosenlicht, NZ; Schoenfeld, FB, 2003) |
| "Nefazodone is a unique serotonergic antidepressant that acts as both a presynaptic serotonin reuptake inhibitor and a postsynaptic 5-hydroxytryptamine 2A receptor antagonist." | 2.71 | A placebo-controlled study of nefazodone for the treatment of chronic posttraumatic stress disorder: a preliminary study. ( Ambrose, S; Bartolucci, A; Davis, LL; English, B; Farley, J; Jewell, ME; Petty, F, 2004) |
| "Posttraumatic stress disorder (PTSD) is a prevalent condition that has been shown to be responsive to pharmacotherapy." | 2.71 | Comparison of nefazodone and sertraline for the treatment of posttraumatic stress disorder. ( Bayles-Dazet, W; Brady, KT; Killeen, TK; McRae, AL; Mellman, TA; Sonne, SC; Timmerman, MA, 2004) |
| "Overall PTSD symptoms as measured by the Clinician-Administered PTSD Scale (CAPS) showed a modest but statistically significant decrease with nefazodone treatment." | 2.70 | Open trial of nefazodone for combat veterans with posttraumatic stress disorder. ( Fichtner, CG; Garfield, DA; Leveroni, C; Mahableshwarkar, A, 2001) |
| "A subgroup of PTSD patients received either fluoxetine or placebo in a clinical trial, and a significant SPAN score improvement was observed on fluoxetine." | 2.69 | Derivation of the SPAN, a brief diagnostic screening test for post-traumatic stress disorder. ( Churchill, E; Davidson, JR; Meltzer-Brody, S, 1999) |
| "Nefazodone treatment was well tolerated by this patient population, with only four patients discontinuing because of adverse effects." | 2.69 | Nefazodone treatment for chronic posttraumatic stress disorder: an open trial. ( Davis, LL; Kramer, GL; Murray, J; Nugent, AL; Petty, F, 2000) |
| "Posttraumatic stress disorder (PTSD) is a highly prevalent and often chronic disorder among combat veterans, persisting in as many as 15% of Vietnam veterans for at least 20 years." | 2.69 | Nefazodone in patients with treatment-refractory posttraumatic stress disorder. ( Chentsova-Dutton, YE; Ellenor, GL; Gillin, JC; Kline, NA; Kodsi, AB; Smith-Vaniz, A; Zisook, S, 2000) |
| "Posttraumatic stress disorder (PTSD) is a prevalent and disabling condition." | 2.41 | Pharmacotherapy of posttraumatic stress disorder: treatment options, long-term follow-up, and predictors of outcome. ( Davidson, JR, 2000) |
| "Nefazodone was associated with statistically significant improvement in mean scores on all six rating scales used to assess change from baseline in PTSD symptoms." | 1.30 | Treatment of posttraumatic stress disorder with nefazodone. ( Connor, KM; Davidson, JR; Malik, ML; Weisler, RH, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brownlow, JA | 1 |
| Harb, GC | 1 |
| Ross, RJ | 1 |
| Lee, DJ | 1 |
| Schnitzlein, CW | 1 |
| Wolf, JP | 1 |
| Vythilingam, M | 1 |
| Rasmusson, AM | 1 |
| Hoge, CW | 1 |
| Neylan, TC | 1 |
| Lenoci, M | 1 |
| Maglione, ML | 1 |
| Rosenlicht, NZ | 1 |
| Leykin, Y | 1 |
| Metzler, TJ | 1 |
| Schoenfeld, FB | 1 |
| Marmar, CR | 1 |
| Davis, LL | 2 |
| Jewell, ME | 1 |
| Ambrose, S | 1 |
| Farley, J | 1 |
| English, B | 1 |
| Bartolucci, A | 1 |
| Petty, F | 3 |
| McRae, AL | 1 |
| Brady, KT | 1 |
| Mellman, TA | 1 |
| Sonne, SC | 1 |
| Killeen, TK | 1 |
| Timmerman, MA | 1 |
| Bayles-Dazet, W | 1 |
| Martényi, F | 1 |
| Davidson, JR | 3 |
| Weisler, RH | 1 |
| Malik, ML | 1 |
| Connor, KM | 1 |
| Hidalgo, R | 1 |
| Hertzberg, MA | 1 |
| Mellman, T | 1 |
| Tucker, P | 1 |
| Weisler, R | 1 |
| Zisook, S | 2 |
| Chen, S | 1 |
| Churchill, E | 2 |
| Davidson, J | 1 |
| Meltzer-Brody, S | 1 |
| Nugent, AL | 1 |
| Murray, J | 1 |
| Kramer, GL | 1 |
| Chentsova-Dutton, YE | 1 |
| Smith-Vaniz, A | 1 |
| Kline, NA | 1 |
| Ellenor, GL | 1 |
| Kodsi, AB | 1 |
| Gillin, JC | 1 |
| Domon, SE | 1 |
| Andersen, MS | 1 |
| Garfield, DA | 1 |
| Fichtner, CG | 1 |
| Leveroni, C | 1 |
| Mahableshwarkar, A | 1 |
4 reviews available for nefazodone and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Treatment of Sleep Disturbances in Post-Traumatic Stress Disorder: A Review of the Literature.
Topics: Antipsychotic Agents; Cognitive Behavioral Therapy; Dreams; Eye Movement Desensitization Reprocessin | 2015 |
PSYCHOTHERAPY VERSUS PHARMACOTHERAPY FOR POSTTRAUMATIC STRESS DISORDER: SYSTEMIC REVIEW AND META-ANALYSES TO DETERMINE FIRST-LINE TREATMENTS.
Topics: Antidepressive Agents; Combined Modality Therapy; Humans; Piperazines; Psychotherapy; Randomized Con | 2016 |
[Three paradigms in the treatment of posttraumatic stress disorder].
Topics: Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Benzodiazepines; Combat Disorders; Co | 2005 |
Pharmacotherapy of posttraumatic stress disorder: treatment options, long-term follow-up, and predictors of outcome.
Topics: Anticonvulsants; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Fluoxetine; Follow-Up S | 2000 |
8 trials available for nefazodone and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
The effect of nefazodone on subjective and objective sleep quality in posttraumatic stress disorder.
Topics: Antidepressive Agents, Second-Generation; Chronic Disease; Drug Administration Schedule; Humans; Mal | 2003 |
A placebo-controlled study of nefazodone for the treatment of chronic posttraumatic stress disorder: a preliminary study.
Topics: Adult; Aged; Analysis of Variance; Combat Disorders; Double-Blind Method; Female; Humans; Male; Midd | 2004 |
Comparison of nefazodone and sertraline for the treatment of posttraumatic stress disorder.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Double-Blind Method; Female; Huma | 2004 |
Nefazodone in post-traumatic stress disorder: results from six open-label trials.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Female; Humans; Male; Midd | 1999 |
Derivation of the SPAN, a brief diagnostic screening test for post-traumatic stress disorder.
Topics: Adult; Antidepressive Agents; Cohort Studies; Combat Disorders; Disasters; Female; Fluoxetine; Fluvo | 1999 |
Nefazodone treatment for chronic posttraumatic stress disorder: an open trial.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Chronic Disease; Combat Disorders; Female; Hu | 2000 |
Nefazodone in patients with treatment-refractory posttraumatic stress disorder.
Topics: Ambulatory Care; Antidepressive Agents, Second-Generation; Chronic Disease; Circadian Rhythm; Combat | 2000 |
Open trial of nefazodone for combat veterans with posttraumatic stress disorder.
Topics: Adult; Antidepressive Agents, Second-Generation; Combat Disorders; Drug Administration Schedule; Hum | 2001 |
2 other studies available for nefazodone and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Treatment of posttraumatic stress disorder with nefazodone.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Arousal; Chronic Disease; Dose-Re | 1998 |
Nefazodone for PTSD.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Arousal; Humans; Piperazines; Stress Disorders | 2000 |