natriuretic-peptide--c-type and Hemorrhage

natriuretic-peptide--c-type has been researched along with Hemorrhage* in 1 studies

Other Studies

1 other study(ies) available for natriuretic-peptide--c-type and Hemorrhage

Article	Year
Central C-type natriuretic peptide augments the hormone response to hemorrhage in conscious sheep. Peptides, 1995, Volume: 16, Issue:1 The effect of intracerebroventricular infusions of C-type natriuretic peptide (CNP-22, 5 micrograms/h for 3 h) or vehicle on the neurohumoral response of conscious sheep (n = 7) to acute moderate hemorrhage (15 ml/kg in 15 min performed 1 h after start of CNP) was studied. CNP alone (prehemorrhage) induced a transient rise (after 30 min) in heart rate (p = 0.0005), plasma aldosterone (p = 0.007), ACTH (p = 0.049), and cortisol (p = 0.049), with values returning to control levels immediately prehemorrhage. Hemorrhage caused arterial pressure to fall (15 mmHg) and heart rate to rise similarly on both study days. Compared with vehicle, posthemorrhage responses of AVP (p = 0.05) and cortisol (p = 0.004) were greater during CNP. Thus, central CNP-22 augmented the hypothalamic-pituitary-adrenal axis at baseline and in response to hemorrhage in conscious sheep. Topics: Animals; Atrial Natriuretic Factor; Female; Hemorrhage; Injections, Intraventricular; Natriuretic Peptide, C-Type; Neurotransmitter Agents; Proteins; Sheep	1995

Article

Year

Central C-type natriuretic peptide augments the hormone response to hemorrhage in conscious sheep.

Peptides, 1995, Volume: 16, Issue:1

The effect of intracerebroventricular infusions of C-type natriuretic peptide (CNP-22, 5 micrograms/h for 3 h) or vehicle on the neurohumoral response of conscious sheep (n = 7) to acute moderate hemorrhage (15 ml/kg in 15 min performed 1 h after start of CNP) was studied. CNP alone (prehemorrhage) induced a transient rise (after 30 min) in heart rate (p = 0.0005), plasma aldosterone (p = 0.007), ACTH (p = 0.049), and cortisol (p = 0.049), with values returning to control levels immediately prehemorrhage. Hemorrhage caused arterial pressure to fall (15 mmHg) and heart rate to rise similarly on both study days. Compared with vehicle, posthemorrhage responses of AVP (p = 0.05) and cortisol (p = 0.004) were greater during CNP. Thus, central CNP-22 augmented the hypothalamic-pituitary-adrenal axis at baseline and in response to hemorrhage in conscious sheep.

Topics: Animals; Atrial Natriuretic Factor; Female; Hemorrhage; Injections, Intraventricular; Natriuretic Peptide, C-Type; Neurotransmitter Agents; Proteins; Sheep

1995