natriuretic-peptide--brain and Sjogren-s-Syndrome

To report a case of secondary pulmonary arterial hypertension (PAH) and the relationship of intraocular pressure (IOP) change with right ventricular diameter (RVD) and brain natriuretic peptide (BNP).. Case report.. A 22-year-old woman with dilated and congested conjunctival and episcleral veins was diagnosed with high IOP. She was previously diagnosed with Sjögren syndrome and suffered from secondary PAH.. The RVD and BNP level improved and the IOP decreased with routine treatment for PAH. During self-cessation of treatment for PAH, the RVD, BNP level, and IOP deteriorated. However, they improved after treatment was reinitiated.. There was a synchronizing change in the parameters representing high pulmonary arterial pressure and IOP during treatment of PAH.

Topics: Antihypertensive Agents; Atrial Pressure; Conjunctiva; Diuretics; Drug Therapy, Combination; Female; Heart Ventricles; Humans; Hypertension, Pulmonary; Intraocular Pressure; Natriuretic Peptide, Brain; Ocular Hypertension; Sclera; Sjogren's Syndrome; Vasodilator Agents; Young Adult

Cardiac resynchronization therapy (CRT) has been proven its value in adult patients with congestive heart failure of low ejection fraction and wide QRS duration. Contrast to adult patients, CRT has been rarely applied for young patients. We report on a 9-yr-old boy with progressive left ventricular (LV) dilatation and dysfunction following chronic VVI pacemaker therapy for congenital complete atrioventricular block associated with maternal anti-SSA/Ro and SSB/La antibody. His LV dysfunction was improved after epicardially established CRT.

Topics: Antibodies, Antinuclear; Atrioventricular Block; Cardiac Pacing, Artificial; Cardiac Resynchronization Therapy; Child; Chronic Disease; Electrocardiography; Heart Ventricles; Humans; Male; Natriuretic Peptide, Brain; Radiography; Sjogren's Syndrome; Ventricular Dysfunction, Left