natriuretic-peptide--brain and Abnormalities--Multiple

This report describes a transient hypertrophic cardiomyopathy with right-ventricle outlet tract obstruction (RVOTO) induced by perinatal stress due to a major surgical procedure in a female newborn with congenital abnormalities. On day 10, she presented with heart failure, abnormal B-type natriuretic peptide (BNP), and an echocardiogram showing normal wall thickness. An in-hospital follow-up echocardiogram showed biventricular hypertrophy and RVOTO. At discharge, the infant was asymptomatic, with a normal echocardiogram and BNP. Transient RVOTO triggered by surgical stress and abnormal BNP have not been reported previously. Pathophysiology, the role of BNP, and clinical characteristics are discussed.

Topics: Abnormalities, Multiple; Apgar Score; Biomarkers; Cardiomyopathy, Hypertrophic; Cesarean Section; Combined Modality Therapy; Echocardiography, Doppler; Electrocardiography; Female; Follow-Up Studies; Humans; Hydrocephalus; Infant, Newborn; Meningomyelocele; Natriuretic Peptide, Brain; Risk Assessment; Spinal Dysraphism; Takotsubo Cardiomyopathy; Treatment Outcome; Ultrasonography, Prenatal; Ventricular Outflow Obstruction