Compounds > naproxen
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naproxen and Osteoarthritis of Knee

naproxen has been researched along with Osteoarthritis of Knee in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's18 (32.73)29.6817
2010's34 (61.82)24.3611
2020's3 (5.45)2.80

Authors

AuthorsStudies
Liu, M; Martel-Pelletier, J; Pelletier, JP; Rahman, P; Randell, EW; Zhai, G1
Bolognesi, MP; Hsueh, MF; Kraus, VB; Wellman, SS1
Askari, G; Bahreini-Esfahani, N; Gorgian, P; Heidari-Beni, M; Moravejolahkami, AR; Tarrahi, MJ1
Brown, MT; Carrino, JA; Fountaine, RJ; Guermazi, A; Hickman, A; Hochberg, MC; Nakajo, S; Pixton, G; Schnitzer, TJ; Verburg, KM; Viktrup, L; Walsh, DA; West, CR; White, A1
Marin, A; Markotic, F; Puljak, L; Tugwell, P; Utrobicic, A; Vrdoljak, D1
Dale, M; Flores, CM; Frustaci, ME; Katz, N; Manitpisitkul, P; Mayorga, AJ; Moyer, JA; Ratcliffe, S; Romano, G; Shalayda, K; Treister, R; Trudeau, JJ1
An, R; Couto, A; Moon, J; Paredes-Diaz, A; Troullos, E1
Brown, GA; Cummins, DS; Jevsevar, DS; Mullen, K; Schulte, DM; Shores, PB1
Katz, NP; Lawal, OD; Suzan, E; Treister, R1
Bi, B; Duan, X; Lin, F; Wang, C; Wang, F1
Honigman, L; Katz, NP; Lanier, RK; Lawal, OD; Treister, R1
Blauwet, MB; Fakhoury, A; Jacobs, H; Lane, NE; Smulders, R; Watt, FE1
Larsen, CP; Nawaz, FA; Troxell, ML1
Brown, MT; Ekman, EF; Greenberg, HS; Schnitzer, TJ; Smith, MD; Spierings, EL; Verburg, KM; West, CR1
Ali, Z; Contreras-Rodríguez, O; Deus, J; Giménez, M; Llorente-Onaindia, J; López-Solà, M; Monfort, J; Ortiz, H; Pujol, J; Soriano-Mas, C1
Annis, KM; Bello, AE; Brown, MT; Ekman, EF; Gimbel, JS; Keller, DS; Smith, MD; Verburg, KM; West, CR1
Bannuru, RR; Kent, DM; McAlindon, TE; Schmid, CH; Vaysbrot, EE; Wong, JB1
Bao, W; Behar, R; Essex, MN; O'Connell, MA1
Bello, AE; Fort, JG; Grahn, AY; Holt, RJ; Kent, JD1
Collins, JE; Hunter, DJ; Jordan, JM; Katz, JN; Losina, E; Paltiel, AD; Smith, SR; Solomon, DH; Suter, LG; Yelin, E1
Choi, HK; Dalal, DS; Dubreuil, M; Felson, DT; Lee, T; Lu, N; Zhang, Y1
Abram, F; Beaulieu, AD; Bias, P; Choquette, D; Dorais, M; Haraoui, B; Laufer, S; Martel-Pelletier, J; Pelletier, JP; Raynauld, JP; Vignon, E1
Abram, F; Bias, P; Choquette, D; Dorais, M; Emmert, KH; Haraoui, B; Laufer, S; Martel-Pelletier, J; Pelletier, JP; Raynauld, JP1
Aguirre, D; Karlsson, J; Pivodic, A; Schnitzer, TJ1
Burnett, BP; Khokhlov, A; Levy, RM; Saikovsky, R; Shmidt, E1
Beals, CR; Bolognese, JA; Harman, A; Kivitz, AJ; Moskowitz, RW; Peeva, E; Smugar, SS; Taber, L1
Duquesroix, B; Frayssinet, H; Kivitz, A; Schnitzer, TJ1
Abram, F; Caron, J; Choquette, D; Dorais, M; Haraoui, B; Martel-Pelletier, J; Mineau, F; Pelletier, JP; Raynauld, JP1
Abram, F; Dorais, M; Martel-Pelletier, J; Pelletier, JP; Raynauld, JP; Wildi, LM1
Beekman, M; Duquesroix, B; Frayssinet, H; Hochberg, MC; Marrero, CE; Schnitzer, TJ1
Bart, B; Bell, M; Burnett, BP; Caldron, P; Ermolova, T; Kantemirova, R; Khokhlov, A; Kopenkin, S; Levy, RM; Mazurov, V; Pillai, L1
Bart, B; Bell, M; Burnett, B; Caldron, P; Ermolova, T; Kantemirova, R; Khokhlov, A; Kopenkin, S; Levy, R; Mazurov, V; Pillai, L1
Bunjob, M; Chinswangwatanakul, P; Kuptniratsaikul, V; Pinthong, T; Thamlikitkul, V; Thanakhumtorn, S1
Fort, JG; Hochberg, MC; Hwang, C; Sostek, M; Svensson, O1
Abram, F; Choquette, D; Dorais, M; Haraoui, B; Martel-Pelletier, J; Pelletier, JP; Raynauld, JP; Wildi, LM1
Cryer, BL; Fort, JG; Hochberg, MC; Hwang, C; Sostek, MB; Svensson, O1
Bond, M; Davis, A; Hawker, G; Lohmander, S1
Huggins, JP; Langman, S; Smart, TS; Taylor, L; Young, T1
Bhadra, P; Essex, MN; Sands, GH1
Bhadra Brown, P; Essex, MN; O'Connell, M1
Amante, C; Chen, SL; Choon, D; Chow, CT; De Tora, L; Genti, G; Laurenzi, M; Lu, HS; Moan, A; Myllykangas-Luosujärvi, R; Pasero, G; Rodgers, DB; Sarembock, B; Vrijens, F; Zerbini, CA1
Minic, M; Schiff, M1
Chen, LS; Chen, SC; Chen, WJ; Hou, SM; Lai, MS; Wang, CT; Yen, ZS1
Bolin, L; Genti, G; Kalla, A; Lohmander, LS; Malmenäs, M; McKeith, D; Ramos-Remus, C; Svensson, O; Szechinski, J1
Guévremont, M; Laufer, S; Marcouiller, P; Martel-Pelletier, J; Pelletier, JP; Ranger, P; Reboul, P1
Bierma-Zeinstra, SM; Hazes, JM; Koes, BW; Pols, HA; Reijman, M; Stricker, BH1
Fajutrao, L; Lohmander, LS; Malmenäs, M; Roos, EM; Svensson, O1
Hee, A; Kivitz, AJ; Lipetz, RS; Sanders, N; Schnitzer, TJ1
Benson, GD; Schweinle, JE; Temple, AR; Zinsenheim, JR1
Hossain, MS; Shakoor, MA; Taslim, MA1
Bensen, WG1
Cha, HS; Jeon, CH; Kim, JS; Koh, EM; Koh, JH; Lee, CK1
Beaulieu, A; Castro, R; Detora, LM; Gallacher, AE; Leung, AT; Malmstrom, K; Ng, J; Poor, G; Sanchez, M; Sarembock, B1

Reviews

4 review(s) available for naproxen and Osteoarthritis of Knee

ArticleYear
Celecoxib for osteoarthritis.
    The Cochrane database of systematic reviews, 2017, 05-22, Volume: 5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Diclofenac; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Measurement; Placebos; Quality of Life; Randomized Controlled Trials as Topic

2017
Mixed Treatment Comparisons for Nonsurgical Treatment of Knee Osteoarthritis: A Network Meta-analysis.
    The Journal of the American Academy of Orthopaedic Surgeons, 2018, May-01, Volume: 26, Issue:9

    Topics: Acetaminophen; Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; Hyaluronic Acid; Injections, Intra-Articular; Musculoskeletal Pain; Naproxen; Network Meta-Analysis; Osteoarthritis, Knee; Platelet-Rich Plasma

2018
Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: a systematic review and network meta-analysis.
    Annals of internal medicine, 2015, Jan-06, Volume: 162, Issue:1

    Topics: Acetaminophen; Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Hyaluronic Acid; Ibuprofen; Injections, Intra-Articular; Naproxen; Osteoarthritis, Knee; Pain; Pyrazoles; Sulfonamides; Treatment Outcome; Viscosupplements

2015
Antiinflammatory and analgesic efficacy of COX-2 specific inhibition: from investigational trials to clinical experience.
    The Journal of rheumatology. Supplement, 2000, Volume: 60

    Topics: Analgesics; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Clinical Trials, Phase III as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Humans; Isoenzymes; Joints; Membrane Proteins; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Treatment Outcome

2000

Trials

41 trial(s) available for naproxen and Osteoarthritis of Knee

ArticleYear
Serum lysophosphatidylcholines to phosphatidylcholines ratio is associated with symptomatic responders to symptomatic drugs in knee osteoarthritis patients.
    Arthritis research & therapy, 2019, 11-06, Volume: 21, Issue:1

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cyclooxygenase Inhibitors; Female; Humans; Lysophosphatidylcholines; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Phosphatidylcholines; Pyrroles; Treatment Outcome

2019
Herbal formulation "turmeric extract, black pepper, and ginger" versus Naproxen for chronic knee osteoarthritis: A randomized, double-blind, controlled clinical trial.
    Phytotherapy research : PTR, 2020, Volume: 34, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Curcuma; Curcumin; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Piper nigrum; Plant Extracts; Zingiber officinale

2020
Long-Term Safety and Efficacy of Subcutaneous Tanezumab Versus Nonsteroidal Antiinflammatory Drugs for Hip or Knee Osteoarthritis: A Randomized Trial.
    Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Blocking; Antibodies, Monoclonal, Humanized; Celecoxib; Diclofenac; Disease Progression; Double-Blind Method; Female; Fractures, Bone; Fractures, Spontaneous; Humans; Injections, Subcutaneous; Intra-Articular Fractures; Male; Middle Aged; Naproxen; Nerve Growth Factor; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteonecrosis; Treatment Outcome

2021
A randomized study to evaluate the analgesic efficacy of a single dose of the TRPV1 antagonist mavatrep in patients with osteoarthritis.
    Scandinavian journal of pain, 2017, Volume: 17

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Ontario; Osteoarthritis, Knee; TRPV Cation Channels

2017
Analgesic efficacy and safety of non-prescription doses of naproxen sodium in the management of moderate osteoarthritis of the knee or hip.
    Current medical research and opinion, 2018, Volume: 34, Issue:10

    Topics: Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain Measurement; Treatment Outcome

2018
Staircase-evoked Pain May be More Sensitive Than Traditional Pain Assessments in Discriminating Analgesic Effects: A Randomized, Placebo-controlled Trial of Naproxen in Patients With Osteoarthritis of the Knee.
    The Clinical journal of pain, 2019, Volume: 35, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Movement; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Research Design; Rest; Treatment Outcome

2019
A deeper look at pain variability and its relationship with the placebo response: results from a randomized, double-blind, placebo-controlled clinical trial of naproxen in osteoarthritis of the knee.
    Pain, 2019, Volume: 160, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Placebo Effect; ROC Curve; Treatment Outcome

2019
Tropomyosin-related kinase A (TrkA) inhibition for the treatment of painful knee osteoarthritis: results from a randomized controlled phase 2a trial.
    Osteoarthritis and cartilage, 2019, Volume: 27, Issue:11

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain Measurement; Receptor, trkA; Treatment Outcome; Young Adult

2019
Efficacy and safety of tanezumab monotherapy or combined with non-steroidal anti-inflammatory drugs in the treatment of knee or hip osteoarthritis pain.
    Annals of the rheumatic diseases, 2015, Volume: 74, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Arthralgia; Arthroplasty, Replacement; Celecoxib; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans; Hypesthesia; Male; Middle Aged; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Paresthesia; Pyrazoles; Sulfonamides; Treatment Outcome

2015
Naproxen effects on brain response to painful pressure stimulation in patients with knee osteoarthritis: a double-blind, randomized, placebo-controlled, single-dose study.
    The Journal of rheumatology, 2014, Volume: 41, Issue:11

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain; Pain Threshold; Physical Stimulation; Reference Values; Severity of Illness Index

2014
Efficacy and safety of intravenous tanezumab for the symptomatic treatment of osteoarthritis: 2 randomized controlled trials versus naproxen.
    The Journal of rheumatology, 2014, Volume: 41, Issue:11

    Topics: Administration, Oral; Aged; Antibodies, Monoclonal, Humanized; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Middle Aged; Naproxen; Ontario; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Measurement; Patient Safety; Range of Motion, Articular; Risk Assessment; Severity of Illness Index; Treatment Outcome

2014
Efficacy and safety of nonsteroidal anti-inflammatory drugs in Asian patients with knee osteoarthritis: summary of a randomized, placebo-controlled study.
    International journal of rheumatic diseases, 2016, Volume: 19, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Asian; Celecoxib; Disability Evaluation; Double-Blind Method; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain Measurement; Patient Satisfaction; Recovery of Function; Severity of Illness Index; Surveys and Questionnaires; Time Factors; Treatment Outcome

2016
Onset and durability of pain relief in knee osteoarthritis: Pooled results from two placebo trials of naproxen/esomeprazole combination and celecoxib.
    The Physician and sportsmedicine, 2015, Volume: 43, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Proton Pump Inhibitors

2015
Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI.
    Annals of the rheumatic diseases, 2009, Volume: 68, Issue:6

    Topics: Aged; Antirheumatic Agents; Cartilage, Articular; Chi-Square Distribution; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Knee Joint; Lipoxygenase Inhibitors; Magnetic Resonance Imaging; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain Measurement; Pyrroles; Radiography; Treatment Outcome

2009
Analysis of the precision and sensitivity to change of different approaches to assess cartilage loss by quantitative MRI in a longitudinal multicentre clinical trial in patients with knee osteoarthritis.
    Arthritis research & therapy, 2008, Volume: 10, Issue:6

    Topics: Cartilage, Articular; Double-Blind Method; Female; Follow-Up Studies; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pyrroles; Sensitivity and Specificity

2008
Efficacy, safety, and tolerability of the cyclooxygenase-inhibiting nitric oxide donator naproxcinod in treating osteoarthritis of the hip or knee.
    The Journal of rheumatology, 2009, Volume: 36, Issue:6

    Topics: Aged; Antirheumatic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Naproxen; Nitric Oxide Donors; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Severity of Illness Index; Treatment Outcome

2009
Flavocoxid is as effective as naproxen for managing the signs and symptoms of osteoarthritis of the knee in humans: a short-term randomized, double-blind pilot study.
    Nutrition research (New York, N.Y.), 2009, Volume: 29, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Double-Blind Method; Drug Combinations; Female; Flavonoids; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Phytotherapy; Pilot Projects; Plant Extracts; Scutellaria

2009
A walking model to assess the onset of analgesia in osteoarthritis knee pain.
    Osteoarthritis and cartilage, 2010, Volume: 18, Issue:5

    Topics: Acetaminophen; Aged; Analgesics; Cross-Over Studies; Double-Blind Method; Drug Combinations; Exercise Test; Female; Humans; Male; Middle Aged; Models, Biological; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Tramadol; Walking

2010
Efficacy and safety of naproxcinod in the treatment of patients with osteoarthritis of the knee: a 13-week prospective, randomized, multicenter study.
    Osteoarthritis and cartilage, 2010, Volume: 18, Issue:5

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Heart Rate; Humans; Male; Middle Aged; Naproxen; Nitric Oxide Donors; Osteoarthritis, Knee; Pain; Pain Measurement; Prospective Studies; Severity of Illness Index

2010
Decrease in serum level of matrix metalloproteinases is predictive of the disease-modifying effect of osteoarthritis drugs assessed by quantitative MRI in patients with knee osteoarthritis.
    Annals of the rheumatic diseases, 2010, Volume: 69, Issue:12

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; C-Reactive Protein; Cartilage, Articular; Drug Monitoring; Female; Humans; Magnetic Resonance Imaging; Male; Matrix Metalloproteinases; Middle Aged; Naproxen; Osteoarthritis, Knee; Pyrroles; Severity of Illness Index; Treatment Outcome

2010
Relationship between bone marrow lesions, cartilage loss and pain in knee osteoarthritis: results from a randomised controlled clinical trial using MRI.
    Annals of the rheumatic diseases, 2010, Volume: 69, Issue:12

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Diseases; Cartilage, Articular; Cyclooxygenase Inhibitors; Epidemiologic Methods; Female; Humans; Knee Joint; Magnetic Resonance Imaging; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Pyrroles

2010
Efficacy and safety of naproxcinod in patients with osteoarthritis of the knee: a 53-week prospective randomized multicenter study.
    Seminars in arthritis and rheumatism, 2011, Volume: 40, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Nitric Oxide Donors; Osteoarthritis, Knee; Pain; Pain Measurement; Prospective Studies; Treatment Outcome

2011
Efficacy and safety of flavocoxid, a novel therapeutic, compared with naproxen: a randomized multicenter controlled trial in subjects with osteoarthritis of the knee.
    Advances in therapy, 2010, Volume: 27, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Combinations; Female; Gastrointestinal Diseases; Humans; Lipoxygenase Inhibitors; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Respiratory Tract Diseases

2010
Efficacy and safety of flavocoxid compared with naproxen in subjects with osteoarthritis of the knee- a subset analysis.
    Advances in therapy, 2010, Volume: 27, Issue:12

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Double-Blind Method; Drug Combinations; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Treatment Outcome

2010
Efficacy and safety of Derris scandens Benth extracts in patients with knee osteoarthritis.
    Journal of alternative and complementary medicine (New York, N.Y.), 2011, Volume: 17, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Derris; Female; Humans; Knee; Male; Middle Aged; Mobility Limitation; Naproxen; Osteoarthritis, Knee; Pain; Phytotherapy; Plant Components, Aerial; Plant Extracts; Prospective Studies; Severity of Illness Index; Single-Blind Method; Treatment Outcome; Walking

2011
Fixed-dose combination of enteric-coated naproxen and immediate-release esomeprazole has comparable efficacy to celecoxib for knee osteoarthritis: two randomized trials.
    Current medical research and opinion, 2011, Volume: 27, Issue:6

    Topics: Celecoxib; Double-Blind Method; Drug Combinations; Esomeprazole; Humans; Naproxen; Osteoarthritis, Knee; Placebos; Pyrazoles; Sulfonamides; Treatment Outcome

2011
Risk factors predictive of joint replacement in a 2-year multicentre clinical trial in knee osteoarthritis using MRI: results from over 6 years of observation.
    Annals of the rheumatic diseases, 2011, Volume: 70, Issue:8

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; C-Reactive Protein; Disease Progression; Epidemiologic Methods; Female; Humans; Knee Joint; Magnetic Resonance Imaging; Male; Menisci, Tibial; Middle Aged; Naproxen; Osteoarthritis, Knee; Prognosis; Pyrroles; Tibial Meniscus Injuries

2011
A fixed-dose combination of naproxen and esomeprazole magnesium has comparable upper gastrointestinal tolerability to celecoxib in patients with osteoarthritis of the knee: results from two randomized, parallel-group, placebo-controlled trials.
    Annals of medicine, 2011, Volume: 43, Issue:8

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Combinations; Dyspepsia; Esomeprazole; Female; Gastrointestinal Tract; Heartburn; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pyrazoles; Sulfonamides; Tablets, Enteric-Coated; Treatment Outcome

2011
Responsiveness of the OARSI-OMERACT osteoarthritis pain and function measures.
    Osteoarthritis and cartilage, 2012, Volume: 20, Issue:6

    Topics: Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Disability Evaluation; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nitric Oxide Donors; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Severity of Illness Index; Treatment Outcome

2012
An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of th
    Pain, 2012, Volume: 153, Issue:9

    Topics: Adult; Aged; Amidohydrolases; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Cross-Over Studies; Double-Blind Method; Endocannabinoids; Female; Humans; Knee Joint; Male; Medical Futility; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain Measurement; Pyridazines; Single-Blind Method; Treatment Outcome; Urea

2012
Efficacy and tolerability of celecoxib versus naproxen in patients with osteoarthritis of the knee: a randomized, double-blind, double-dummy trial.
    The Journal of international medical research, 2012, Volume: 40, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pyrazoles; Sulfonamides; Treatment Outcome

2012
Response to nonsteroidal anti-inflammatory drugs in African Americans with osteoarthritis of the knee.
    The Journal of international medical research, 2012, Volume: 40, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Black or African American; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain Measurement; Placebo Effect; Placebos; Pyrazoles; Sulfonamides; Treatment Outcome

2012
Comparison of low-dose rofecoxib versus 1000 mg naproxen in patients with osteoarthritis. Results of two randomized treatment trials of six weeks duration.
    Scandinavian journal of rheumatology, 2002, Volume: 31, Issue:6

    Topics: Aged; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Lactones; Male; Middle Aged; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Sulfones; Treatment Outcome

2002
Comparison of the analgesic efficacy and safety of nonprescription doses of naproxen sodium and Ibuprofen in the treatment of osteoarthritis of the knee.
    The Journal of rheumatology, 2004, Volume: 31, Issue:7

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain Measurement; Quality of Life; Treatment Outcome

2004
A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis.
    Annals of the rheumatic diseases, 2005, Volume: 64, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Male; Middle Aged; Naphthalenes; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Peptic Ulcer; Quality of Life; Treatment Outcome

2005
Greater reduction of knee than hip pain in osteoarthritis treated with naproxen, as evaluated by WOMAC and SF-36.
    Annals of the rheumatic diseases, 2006, Volume: 65, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Health Status Indicators; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement

2006
Comparison of the COX-inhibiting nitric oxide donator AZD3582 and rofecoxib in treating the signs and symptoms of Osteoarthritis of the knee.
    Arthritis and rheumatism, 2005, Dec-15, Volume: 53, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Lactones; Male; Middle Aged; Naphthalenes; Naproxen; Osteoarthritis, Knee; Pain Measurement; Severity of Illness Index; Sulfones; Surveys and Questionnaires; Treatment Outcome

2005
Multicenter, randomized, double-blind, active-controlled, parallel-group trial of the long-term (6-12 months) safety of acetaminophen in adult patients with osteoarthritis.
    Clinical therapeutics, 2006, Volume: 28, Issue:2

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Patient Compliance; Treatment Outcome

2006
Effects of activity modification on the patients with osteoarthritis of the knee.
    Bangladesh Medical Research Council bulletin, 2007, Volume: 33, Issue:2

    Topics: Activities of Daily Living; Adult; Aged; Combined Modality Therapy; Exercise Therapy; Female; Humans; Male; Middle Aged; Motor Activity; Naproxen; Osteoarthritis, Knee; Posture; Prospective Studies; Self-Help Devices; Short-Wave Therapy

2007
Comparison of the efficacy and safety of naproxen CR and nabumetone in the treatment of patients with osteoarthritis of the knee.
    International journal of clinical pharmacology and therapeutics, 2001, Volume: 39, Issue:12

    Topics: Activities of Daily Living; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Constipation; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Nausea; Osteoarthritis, Knee; Pain Measurement; Single-Blind Method; Treatment Outcome; Walking

2001
Efficacy and tolerability profile of etoricoxib in patients with osteoarthritis: A randomized, double-blind, placebo and active-comparator controlled 12-week efficacy trial.
    Current medical research and opinion, 2002, Volume: 18, Issue:2

    Topics: Cyclooxygenase 2; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Etoricoxib; Female; Humans; Isoenzymes; Male; Membrane Proteins; Middle Aged; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Prostaglandin-Endoperoxide Synthases; Pyridines; Safety; Sulfones; Treatment Outcome

2002

Other Studies

10 other study(ies) available for naproxen and Osteoarthritis of Knee

ArticleYear
Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial fluid immune cells.
    Osteoarthritis and cartilage, 2020, Volume: 28, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dinoprostone; Flow Cytometry; Humans; Hyaluronic Acid; Inflammation; Interleukin-1beta; Interleukin-6; Interleukin-8; Lipopolysaccharides; Macrophages; Monocytes; Naproxen; Neutrophils; NF-kappa B; Osteoarthritis, Knee; Synovial Fluid; T-Lymphocytes; THP-1 Cells; Tumor Necrosis Factor-alpha

2020
Naproxen attenuates osteoarthritis progression through inhibiting the expression of prostaglandinl-endoperoxide synthase 1.
    Journal of cellular physiology, 2019, Volume: 234, Issue:8

    Topics: Aged; Animals; Cyclooxygenase 1; Female; Humans; Hyaluronic Acid; Male; Membrane Proteins; Mice, Inbred C57BL; Middle Aged; Naproxen; Osteoarthritis, Knee; RNA, Messenger; Synovial Membrane; Synoviocytes

2019
Membranous nephropathy and nonsteroidal anti-inflammatory agents.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2013, Volume: 62, Issue:5

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Cyclophosphamide; Glomerulonephritis, Membranous; Humans; Male; Naproxen; Osteoarthritis, Knee; Piroxicam; Steroids; Treatment Outcome; Withholding Treatment

2013
Cost-effectiveness of nonsteroidal anti-inflammatory drugs and opioids in the treatment of knee osteoarthritis in older patients with multiple comorbidities.
    Osteoarthritis and cartilage, 2016, Volume: 24, Issue:3

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Comorbidity; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Health Services Research; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nonprescription Drugs; Osteoarthritis, Knee; Pain; Pain Measurement; Proton Pump Inhibitors; Quality-Adjusted Life Years; Sensitivity and Specificity; Tramadol; Treatment Outcome; United States

2016
Use of non-steroidal anti-inflammatory drugs correlates with the risk of venous thromboembolism in knee osteoarthritis patients: a UK population-based case-control study.
    Rheumatology (Oxford, England), 2016, Volume: 55, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Lactones; Logistic Models; Male; Meloxicam; Middle Aged; Naproxen; Odds Ratio; Osteoarthritis, Knee; Risk Factors; Sulfones; Thiazines; Thiazoles; Treatment Outcome; United Kingdom; Venous Thromboembolism

2016
[Paracetamol in knee and hip arthrosis is dispensable].
    MMW Fortschritte der Medizin, 2016, Apr-14, Volume: 158, Issue:7

    Topics: Acetaminophen; Diclofenac; Etoricoxib; Humans; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Pyridines; Sulfones; Treatment Outcome

2016
[Progress in therapy of rheumatism. New coxib works especially fast].
    MMW Fortschritte der Medizin, 2003, Jun-05, Volume: 145, Issue:23

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Isoxazoles; Naproxen; Osteoarthritis, Knee; Sulfonamides; Treatment Outcome

2003
Cost-effectiveness of treatment strategies for osteoarthritis of the knee in Taiwan.
    The Journal of rheumatology, 2004, Volume: 31, Issue:9

    Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cost-Benefit Analysis; Female; Humans; Hyaluronic Acid; Middle Aged; Naproxen; Osteoarthritis, Knee; Pyrazoles; Sensitivity and Specificity; Sulfonamides; Taiwan

2004
Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.
    The Journal of rheumatology, 2005, Volume: 32, Issue:4

    Topics: Acetates; Aged; Arachidonic Acid; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; In Vitro Techniques; Leukotriene B4; Lipopolysaccharides; Male; Masoprocol; Naproxen; Osteoarthritis, Knee; Pyrroles; Signal Transduction; Synovial Membrane

2005
Is there an association between the use of different types of nonsteroidal antiinflammatory drugs and radiologic progression of osteoarthritis? The Rotterdam Study.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:10

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Disease Progression; Female; Follow-Up Studies; Humans; Ibuprofen; Logistic Models; Male; Middle Aged; Naproxen; Netherlands; Osteoarthritis, Hip; Osteoarthritis, Knee; Pharmacies; Piroxicam; Radiography; Risk Factors

2005