Page last updated: 2024-09-04

naproxen and Innate Inflammatory Response

naproxen has been researched along with Innate Inflammatory Response in 94 studies

Research

Studies (94)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (13.83)	18.7374
1990's	14 (14.89)	18.2507
2000's	19 (20.21)	29.6817
2010's	39 (41.49)	24.3611
2020's	9 (9.57)	2.80

Authors

Authors	Studies
Kreft, AF; Musser, JH	1
Ackerman, N; Ballaron, SA; Galeazzi, E; Greenhouse, R; Guzmán, A; Muchowski, JM; Peréz, V; Rovito, JR; Tomolonis, AJ; Young, JM	1
Ackrell, J; Cooper, GF; Halpern, O; Kluge, AF; Koehler, R; Muchowski, JM; Simon, RL; Unger, SH; Van Horn, AR; Wren, DL	1
Doulgkeris, CM; Eleftheriou, PT; Galanakis, D; Gavalas, AM; Kourounakis, AP; Kourounakis, PN; Rekka, EA; Tsiakitzis, KC; Victoratos, P	1
Bakthavatchalam, R; Blum, CA; Boyce, S; Brielmann, H; Burnaby-Davies, N; Caldwell, T; Capitosti, S; Chenard, BL; Conley, R; Cortright, D; Crandall, M; De Lombaert, S; Hodgetts, KJ; Jones, AB; Kershaw, MT; Krause, JE; Martin, WJ; Mason, G; Matson, D; Murphy, BA; Perrett, H; Rycroft, W; Zheng, X	1
Afzal, O; Bawa, S; Chawla, G; Deora, GS; Kalle, AM; Kumar, S; Mulakayala, N; Rajaram, A; Rathore, V; Tonk, RK	1
Abbadie, C; Bugianesi, RM; Chakravarty, PK; Dai, G; Duffy, JL; Garcia, ML; Green, M; Haedo, RJ; Herrington, JB; Jochnowitz, N; Kaczorowski, GJ; Li, X; Lyons, KA; McGowan, E; McManus, OB; Mistry, S; Shao, PP; Smith, MM; Sun, SY; Swensen, AM; Varughese, DJ; Warren, VA; Ye, F	1
Arhancet, GB; Baratta, MT; Carter, JS; Fobian, YM; Hayes, MJ; Heasley, SE; Jerome, GM; Jones, DE; Masferrer, JL; Metz, S; Moore, WM; Shaffer, AF; Springer, JR; Vazquez, ML; Walker, DP; Zweifel, B	1
Guo, L; He, G; He, J; Ouyang, L; Pan, J; Shi, J; Wei, J; Zhang, J; Zhou, R	1
Ertan, M; Kazkayasi, I; Okay, G; Ozadali-Sari, K; Sarigol, D; Somuncuoglu, EI; Tel, BC; Tozkoparan, B; Unsal-Tan, O; Uzgoren-Baran, A	1
Anastácio Furtado Pacheco, P; Arruda, JC; Bello, ML; Castro, HC; da Silva, FC; Dantas, LP; de Freitas, HR; de Melo Reis, RA; Faria, RX; Ferreira, LBG; Ferreira, VF; Gonzaga, DTG; Moreira Maramaldo Costa, TE; Penido, C; Rodrigues, CR; Sposito Simões, AP; von Ranke, NL	1
Gou, S; Liu, Z; Wang, C; Zhou, W	1
Abdel-Daim, MM; Akhtar, MF; Alsharif, KF; Saleem, A; Zubair, S	1
Flint, JD; Gilroy, DW; Glanville, JRW; Hosin, AA; Jalali, P; Maini, AA; Patel, AA; Wallace, JL	1
Aguilar, MR; Al-Khoury, H; Espinosa-Cano, E; Groth, T; Román, JS; Schmidt, G; Syrowatka, F	1
Alnouti, Y; Desouza, CV; Heineman, R; Saraswathi, V; Shivaswamy, V	1
Bolognesi, MP; Hsueh, MF; Kraus, VB; Wellman, SS	1
Almáši, M; Bednarčík, J; Hudák, A; Šuleková, M; Szücsová, J; Váhovská, L; Zeleňák, V; Zeleňáková, A; Žid, L	1
Eleftheriou, P; Gavalas, A; Geronikaki, A; Haroun, M; Kamoutsis, C; Kochkar, H; Nair, AB; Paparisva, A; Petrou, A; Tratrat, C; Venugopala, KN	1
Dang, F; Hao, R; Lan, B; Mu, Y; Wang, R; Wu, Y	1
Chang, C; Chen, Y; Han, J; Hua, X; Li, D; Li, L; Li, Z; Liu, Z; Wang, Q; Wang, Z	1
Jarosz, M; Librowski, T; Marona, H; Młyniec, K; Nowak, G; Szkaradek, N	1
Baek, JS; Lee, YH; Loo, SCJ; Tan, NS; Yeo, EW	1
Radhakrishnan, J; Radhakrishnan, R; Yellepeddi, VK	1
Chen, Z; Cheng, L; Feng, G	1
Almutairi, A; Hamelmann, N; Lee, S; Stubelius, A; Tran, V	1
Afraei, S; Hosseini, M; Jamshidi, AR; Khadem Azarian, S; Mahmoudi, M; Mirshafiey, A; Mostafaei, S; Nazeri, S; Vojdanian, M	1
Bolboacă, SD; Bulboacă, AC; Bulboacă, AE; Dogaru, G; Porfire, AS; Stănescu, IC; Suciu, ȘM; Tefas, LR	1
Christoph, T; Leipelt, A; Pasqualon, T; Read, SJ; Robens, A; Rutten, K; Schiene, K	1
Bahde, R; Gupta, S; Kapoor, S	1
Das, MR; Dastidar, P; Deb, J; Jana, SS; Majumder, J	1
Eissa, SI; Farrag, AM; Galeel, AA	1
Nalamachu, S; Wortmann, R	1
Gouveia, FS; Lopes, LG; Lucetti, LT; Medeiros, JV; Ribeiro, RA; Santana, AP; Soares, PM; Sousa, EH; Souza, MH; Tavares, BM	1
Gemici, B; Wallace, JL	1
Bercik, P; Blackler, RW; Buret, AG; Da Silva, GJ; De Palma, G; Flannigan, KL; Manko, A; Surette, MG; Wallace, JL	1
Dixit, D; Ilango, K; Kathiravan, MK; Kumar, G; Nilewar, S; Valentina, P	1
Bentley, JP; Brewer, CB; Day, LB; Waddell, DE	1
Dendrinou-Samara, C; Georgiadou, V; Makris, G; Papagiannopoulou, D; Vourlias, G	1
Olender, D; Pawełczyk, A; Sowa-Kasprzak, K; Zaprutko, L	1
El Azhary, NM; Mostafa, DK; Nasra, RA	1
Brozoski, DT; Calvo, AM; Dionísio, TJ; Faria, FA; Lauris, JR; Santos, CF; Simoneti, LF; Torres, EA; Weckwerth, GM; Zupelari-Gonçalves, P	1
González-Gay, MA; González-Juanatey, C	1
Dial, EJ; Lichtenberger, LM; Moore, JE; Romero, JJ	1
Danhof, M; Della Pasqua, OE; Huntjens, DR; Spalding, DJ	1
Han, CD; Kim, YH; Lee, JW; Paik, S; Yoo, JH; Yoon, DS	1
Haberer, LJ; Lener, SE; McDonald, SA; Taylor, DR; Walls, CM	1
Aguilar-Robles, P; Castañeda-Hernández, G; González-García, MP; Ortiz, MI; Ponce-Monter, HA	1
Ghosal, K; Pimplikar, SW; Stathopoulos, A	1
Bani, D; Bolla, M; Masini, E; Pini, A; Viappiani, S	1
Armagan, G; Kanit, L; Yalcin, A	1
Barbosa, AL; Bezerra, TS; Carvalho, NS; Chaves, LS; Damasceno, SR; Freitas, AL; Medeiros, JV; Oliveira, CB; Santana, AP; Silva, RO; Soares, PM; Souza, MH	1
Backhouse, N; Delporte, C; Feliciano, SA; López-Pérez, JL; Negrete, R	1
Evans, R	1
Bobbaers, HJ; Knockaert, DC; Peetermans, WE; Vanderschueren, S	1
Roach, JT; Sufka, KJ	1
Lovell, DJ; Sullivan, K; Zaoutis, TE	1
Branch, CD; Gopalan, B; Ito, I; Ramesh, R; Roth, JA; Stephens, C	1
Jain, NK; Kulkarni, SK; Sharma, S	1
Augustyniak, ME; Cochran, ED; Earl, RA; Ellis, JL; Garvey, DS; Gordon, LJ; Janero, DR; Khanapure, SP; Letts, LG; Melim, TL; Murty, MG; Schwalb, DJ; Selig, WM; Shumway, MJ; Trocha, AM; Young, DV; Zemtseva, IS	1
Cirino, G; Distrutti, E; Wallace, JL	1
Hilário, MO; Len, CA; Terreri, MT	1
Atmaca, Y; Erol, C; Gulec, S; Ozdol, C; Rahimov, U; Turhan, S	1
Barrett, TD; Hong, TT; Huang, J; Lucchesi, BR	1
Ballaron, SJ; De Young, LM; Puhvel, SM; Spires, DA; Young, JM	1
Colombo, G; Glässer, A; Luzzani, F; Schiatti, P; Selva, D	1
Ballaron, SJ; Bedord, CJ; De Young, LM; Spires, DA; Wagner, B; Young, JM	1
Snow, D	1
Ferrari Parabita, G; Rossi, D; Scalvini, F; Scaricabarozzi, I; Zanetti, U	1
Bechi, P; Nava, ML; Panconesi, R; Scaricabarozzi, I; Zuckermann, M	1
Casini-Raggi, V; Cominelli, F; Laine, L; Marin-Sorensen, M; Sloane, R; Weinstein, WM	1
Breton, J; Griswold, DE; Marshall, PJ; Torphy, TJ; Webb, EF; White, JR	1
Clarke, GD; MacPherson, IS; Petrone, G; Spangler, RS	1
Castañeda-Hernández, G; Favari, L; Hoyo-Vadillo, C	1
Griswold, DE; Tzimas, MN	1
Medvedeff, ED; Nickerson-Nutter, CL	1
Aabakken, L; Meling, TR; Osnes, M; Røseth, A	1
Akatsu, T; Consolaro, A; Guimarães, SA; Tago, EM	1
Asselin, I; Célestin, F; Entman, M; Goulet, M; Guérette, B; Huard, C; Roy, B; Roy, R; Skuk, D; Tardif, F; Tremblay, JP	1
Cullen , DJ; Doherty, M; Garner, S; Garrud, P; Hawkey, CJ; Holmes, S; Logan, RF; Maynard, A; Seager, JM; Wilson, JV	1
Asfaha, S; McKnight, W; Muscará, MN; Wallace, JL	1
Bucci, M; Calignano, A; Cicala, C; Cirino, G; Fiorucci, S; Gerli, R; Ianaro, A; Santucci, L; Wallace, JL	1
Asanuma, M; Kohno, M; Miyazaki, I; Nishibayashi-Asanuma, S; Ogawa, N	1
Fyllingen, G; Haugstvedt, JR; Husby, T; Skoglund, LA	1
Ito, M; Suzuki, Y; Yamagami, I	1
Anttila, M; Dean, PB; Doherty, NS	1
Adamska-Dyniewska, H; Dziekański, S; Goch, JH; Kowalczyk, L; Rec, A; Szeszko, A; Tkaczewski, W	1
Calhoun, W; Carlson, RP; Copenhaver, TW; Datko, LJ; Gilman, SC	1
Castellanos, R; Feria Velasco, A; López-Fiesco, A; Mejia, S; Zamora Lopez, G	1
Griswold, DE; Hanna, N; Schwartz, L; Webb, E	1
Gustafson, GT; Lerner, UH	1
Ferrari Parabita, S; Maffi, F; Moniaci, D; Pellati, D; Rivetti, M	1
Baracos, VE; Gale, R; Whitmore, WT	1

Reviews

4 review(s) available for naproxen and Innate Inflammatory Response

Article	Year
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors. Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14 Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines	1992
Role of indomethacin in acute pain and inflammation management: a review of the literature. Postgraduate medicine, 2014, Volume: 126, Issue:4 Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Humans; Indomethacin; Inflammation; Ketorolac; Naproxen; Oxycodone; Piroxicam; Tramadol; Treatment Outcome	2014
Nitric oxide and inflammation. Inflammation & allergy drug targets, 2006, Volume: 5, Issue:2 Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Inflammation; Naproxen; Nitrates; Nitric Oxide	2006
Nonsteroidal anti-inflammatory drugs: cyclooxygenase 2 inhibitors. Jornal de pediatria, 2006, Volume: 82, Issue:5 Suppl Topics: Adolescent; Aspirin; Celecoxib; Child; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Interactions; Etoricoxib; Fever; Humans; Hypersensitivity, Immediate; Inflammation; Leukotrienes; Meloxicam; Naproxen; Pain; Prostaglandins; Pyrazoles; Pyridines; Sulfonamides; Sulfones; Thiazines; Thiazoles; Treatment Outcome	2006

Trials

12 trial(s) available for naproxen and Innate Inflammatory Response

Article	Year
Potent anti-inflammatory effects of an H FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:10 Topics: Adolescent; Adult; Dinoprostone; Escherichia coli; Humans; Hydrogen Sulfide; Inflammation; Male; Middle Aged; Monocytes; Naproxen; Neutrophils; Pain; Phenotype; Solubility; Ultraviolet Rays; Vasoconstriction; Young Adult	2021
A combination of Omega-3 PUFAs and COX inhibitors: A novel strategy to manage obesity-linked dyslipidemia and adipose tissue inflammation. Journal of diabetes and its complications, 2020, Volume: 34, Issue:2 Topics: Adipose Tissue; Adult; Biopsy; Cyclooxygenase Inhibitors; Dyslipidemias; Fatty Acids, Omega-3; Female; Fish Oils; Humans; Inflammation; Male; Middle Aged; Naproxen; Obesity; Overweight; Pilot Projects; Prospective Studies; Triglycerides	2020
The safety and efficacy of Guluronic acid (G2013) in ankylosing spondylitis: A randomized controlled parallel clinical trial. Pharmacological reports : PR, 2019, Volume: 71, Issue:3 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Hexuronic Acids; Humans; Inflammation; Male; Naproxen; Spondylitis, Ankylosing; Treatment Outcome	2019
Results of a follow-up study to the randomized Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT). Alzheimer's & dementia : the journal of the Alzheimer's Association, 2013, Volume: 9, Issue:6 Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents; Celecoxib; Cognition Disorders; Double-Blind Method; Female; Humans; Inflammation; Longitudinal Studies; Male; Naproxen; Physical Examination; Pyrazoles; Sulfonamides; Treatment Outcome	2013
Efficacy of naproxen with or without esomeprazole for pain and inflammation in patients after bilateral third molar extractions: A double blinded crossover study. Medicina oral, patologia oral y cirugia bucal, 2017, Jan-01, Volume: 22, Issue:1 Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Esomeprazole; Female; Humans; Inflammation; Male; Molar, Third; Naproxen; Pain Management; Pain, Postoperative; Proton Pump Inhibitors; Tooth Extraction; Treatment Outcome; Young Adult	2017
Distinct pharmacokinetic profile and safety of a fixed-dose tablet of sumatriptan and naproxen sodium for the acute treatment of migraine. Headache, 2010, Volume: 50, Issue:3 Topics: Acute Disease; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Compounding; Drug Synergism; Female; Humans; Inflammation; Male; Middle Aged; Migraine Disorders; Naproxen; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome	2010
Naproxen treatment prevents periprocedural inflammatory response but not myocardial injury after percutaneous coronary intervention. Thrombosis research, 2007, Volume: 119, Issue:4 Topics: Aged; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; C-Reactive Protein; Clopidogrel; Creatine Kinase, MB Form; Drug Combinations; Female; Follow-Up Studies; Humans; Inflammation; Intraoperative Period; Male; Middle Aged; Myocardial Infarction; Naproxen; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Treatment Outcome; Troponin I	2007
A controlled clinical study of the efficacy and tolerability of nimesulide vs naproxen in maxillo-facial surgery. Drugs, 1993, Volume: 46 Suppl 1 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Face; Female; Humans; Inflammation; Male; Maxilla; Middle Aged; Naproxen; Postoperative Complications; Sulfonamides; Surgery, Oral	1993
Clinical efficacy and tolerability of nimesulide compared with naproxen in the treatment of posthaemorrhoidectomy pain and inflammation. Drugs, 1993, Volume: 46 Suppl 1 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Hemorrhoids; Humans; Inflammation; Male; Middle Aged; Naproxen; Pain, Postoperative; Postoperative Complications; Sulfonamides	1993
Interaction of NSAIDs and Helicobacter pylori on gastrointestinal injury and prostaglandin production: a controlled double-blind trial. Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:2 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Etodolac; Gastrointestinal Diseases; Helicobacter Infections; Helicobacter pylori; Humans; Inflammation; Middle Aged; Naproxen; Prostaglandins; Stomach Ulcer	1995
Faecal calprotectin shedding after short-term treatment with non-steroidal anti-inflammatory drugs. Scandinavian journal of gastroenterology, 1996, Volume: 31, Issue:4 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Feces; Gastric Mucosa; Humans; Indomethacin; Inflammation; Intestinal Mucosa; Leukocyte L1 Antigen Complex; Male; Naproxen; Neural Cell Adhesion Molecules; Piroxicam; Reproducibility of Results	1996
Acute postoperative swelling after hand surgery: an exploratory, double-blind, randomised study with paracetamol, naproxen, and placebo. Scandinavian journal of plastic and reconstructive surgery and hand surgery, 2001, Volume: 35, Issue:1 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Carpal Tunnel Syndrome; Double-Blind Method; Dupuytren Contracture; Edema; Female; Hand; Humans; Inflammation; Male; Middle Aged; Naproxen	2001

Other Studies

78 other study(ies) available for naproxen and Innate Inflammatory Response

Article	Year
Synthesis and antiinflammatory and analgesic activity of 5-aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-ca rboxyl ic acids and 1-methyl-4-(methylthio)-5-aroylpyrrole-2-acetic acids. Journal of medicinal chemistry, 1989, Volume: 32, Issue:6 Topics: Acetates; Analgesia; Animals; Aspirin; Benzoquinones; Carboxylic Acids; Carrageenan; Chemical Phenomena; Chemistry; Edema; Inflammation; Mice; Molecular Structure; Pain Measurement; Phenylbutazone; Pyrroles; Quinones; Rats	1989
Synthesis and antiinflammatory and analgesic activity of 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids. The 6-substituted compounds. Journal of medicinal chemistry, 1987, Volume: 30, Issue:5 Topics: Analgesia; Animals; Carboxylic Acids; Chemical Phenomena; Chemistry; Inflammation; Magnetic Resonance Spectroscopy; Mice; Pyrroles; Rats; Structure-Activity Relationship	1987
Synthesis and pharmacochemical study of novel polyfunctional molecules combining anti-inflammatory, antioxidant, and hypocholesterolemic properties. Bioorganic & medicinal chemistry letters, 2006, Feb-15, Volume: 16, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antioxidants; Arthritis; Cholesterol; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Female; Inflammation; Pipecolic Acids; Proline; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triglycerides	2006
Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists. Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8 Topics: Analgesics; Animals; Biological Availability; Capsaicin; Chlorocebus aethiops; COS Cells; Hot Temperature; Humans; Hyperalgesia; In Vitro Techniques; Inflammation; Microsomes, Liver; Naphthyridines; Pain; Pyrazines; Pyridines; Pyrimidines; Quinazolines; Quinolines; Rats; Structure-Activity Relationship; TRPV Cation Channels	2010
Synthesis and pharmacological evaluation of pyrazolo[4,3-c]cinnoline derivatives as potential anti-inflammatory and antibacterial agents. European journal of medicinal chemistry, 2012, Volume: 57 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase 2; Edema; Escherichia coli; Heterocyclic Compounds, 2-Ring; Inflammation; Lipid Peroxidation; Microbial Sensitivity Tests; Molecular Docking Simulation; Naproxen; Pseudomonas aeruginosa; Pyrazoles; Rats; Rats, Wistar; Staphylococcus aureus; Structure-Activity Relationship; Ulcer	2012
Aminopiperidine sulfonamide Cav2.2 channel inhibitors for the treatment of chronic pain. Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22 Topics: Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Cells, Cultured; Chronic Pain; Dogs; Humans; Hyperalgesia; Inflammation; Mice; Mice, Knockout; Microsomes, Liver; Neuralgia; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Sulfonamides; Tissue Distribution	2012
Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation. Bioorganic & medicinal chemistry letters, 2013, Feb-15, Volume: 23, Issue:4 Topics: Anti-Inflammatory Agents; Drug Discovery; Enzyme Inhibitors; Humans; Inflammation; Intramolecular Oxidoreductases; Prostaglandin-E Synthases; Structure-Activity Relationship	2013
Design, synthesis and biological evaluation of enzymatically cleavable NSAIDs prodrugs derived from self-immolative dendritic scaffolds for the treatment of inflammatory diseases. Bioorganic & medicinal chemistry, 2013, Jul-15, Volume: 21, Issue:14 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dendrimers; Drug Delivery Systems; Drug Design; Humans; Inflammation; Magnetic Resonance Spectroscopy; Mice; Naproxen; Prodrugs; Stomach Ulcer	2013
Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies. Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Drug Design; Edema; Humans; Inflammation; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Naproxen; Nociception; Pain; Pain Measurement; Structure-Activity Relationship; Thiazoles; Thiones; Triazoles	2015
1-Aryl-1H- and 2-aryl-2H-1,2,3-triazole derivatives blockade P2X7 receptor in vitro and inflammatory response in vivo. European journal of medicinal chemistry, 2017, Oct-20, Volume: 139 Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Inflammation; Lipopolysaccharides; Mice; Molecular Structure; Pleurisy; Receptors, Purinergic P2X7; Structure-Activity Relationship; Triazoles	2017
Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia. Journal of medicinal chemistry, 2022, 10-13, Volume: 65, Issue:19 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Hypoxia; Inflammation; Nitroreductases; Prodrugs	2022
Comparison of individual and combination treatments with naproxen, prednisolone and hydroxychloroquine to treat Complete Freund's Adjuvant induced arthritis. Inflammopharmacology, 2021, Volume: 29, Issue:6 Topics: Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Experimental; Erythrocytes; Female; Freund's Adjuvant; Humans; Hydroxychloroquine; Inflammation; Male; Naproxen; Oxidative Stress; Prednisolone; Rats; Rats, Wistar	2021
Anti-inflammatory Surface Coatings Based on Polyelectrolyte Multilayers of Heparin and Polycationic Nanoparticles of Naproxen-Bearing Polymeric Drugs. Biomacromolecules, 2019, 10-14, Volume: 20, Issue:10 Topics: Anti-Inflammatory Agents; Cell Adhesion; Cell Line; Chitosan; Coated Materials, Biocompatible; Heparin; Humans; Inflammation; Interleukin-1beta; Macrophages; Nanoparticles; Naproxen; Polyelectrolytes; Polymers; Polystyrenes; Surface Properties	2019
Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial fluid immune cells. Osteoarthritis and cartilage, 2020, Volume: 28, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dinoprostone; Flow Cytometry; Humans; Hyaluronic Acid; Inflammation; Interleukin-1beta; Interleukin-6; Interleukin-8; Lipopolysaccharides; Macrophages; Monocytes; Naproxen; Neutrophils; NF-kappa B; Osteoarthritis, Knee; Synovial Fluid; T-Lymphocytes; THP-1 Cells; Tumor Necrosis Factor-alpha	2020
Mesoporous Silica as a Drug Delivery System for Naproxen: Influence of Surface Functionalization. Molecules (Basel, Switzerland), 2020, Oct-15, Volume: 25, Issue:20 Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Drug Delivery Systems; Humans; Inflammation; Naproxen; Porosity; Silicon Dioxide; Solvents; Surface Properties	2020
New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5 Molecules (Basel, Switzerland), 2021, Jan-27, Volume: 26, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Female; Humans; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Molecular Docking Simulation; Naproxen; Structure-Activity Relationship; Triazoles	2021
The protective effects of naproxen against interleukin-1β (IL-1β)- induced damage in human umbilical vein endothelial cells (HUVECs). Bioengineered, 2021, Volume: 12, Issue:1 Topics: Cell Adhesion; Cytokines; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Interleukin-1beta; Naproxen; Protective Agents; Signal Transduction; THP-1 Cells	2021
Albumin-encapsulated Nanoparticles of Naproxen Platinum(IV) Complexes with Inflammation Inhibitory Competence Displaying Effective Antitumor Activities in vitro and in vivo. International journal of nanomedicine, 2021, Volume: 16 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Humans; Inflammation; Mice; Nanoparticles; Naproxen; Platinum; Serum Albumin, Bovine	2021
Evaluation of anti-inflammatory and ulcerogenic potential of zinc-ibuprofen and zinc-naproxen complexes in rats. Inflammopharmacology, 2017, Volume: 25, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Carrageenan; Edema; Gastric Mucosa; Ibuprofen; Inflammation; Male; Naproxen; Organometallic Compounds; Rats; Rats, Wistar; Zinc; Zinc Compounds	2017
Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases. Drug design, development and therapy, 2017, Volume: 11 Topics: Anti-Inflammatory Agents, Non-Steroidal; Capsules; Celecoxib; Cimetidine; Delayed-Action Preparations; Diffusion; Drug Combinations; Drug Compounding; Drug Liberation; Drug Stability; Gastric Juice; Histamine H2 Antagonists; Ibuprofen; Inflammation; Kinetics; Models, Chemical; Nanocapsules; Nanotechnology; Naproxen; Polymers; Solubility; Technology, Pharmaceutical	2017
Penetration and pharmacokinetics of non-steroidal anti-inflammatory drugs in rat prostate tissue. The Prostate, 2018, Volume: 78, Issue:2 Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Celecoxib; Chromatography, Liquid; Comparative Effectiveness Research; Diclofenac; Disease Models, Animal; Ibuprofen; Inflammation; Male; Naproxen; Pelvic Pain; Prostate; Prostatitis; Rats; Rats, Sprague-Dawley; Tissue Distribution	2018
Bone inflammation and chronic recurrent multifocal osteomyelitis. European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:5 Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; C-Reactive Protein; Child; Child, Preschool; Diagnosis, Differential; Diphosphonates; Female; Humans; Inflammation; Magnetic Resonance Imaging; Male; Naproxen; Osteomyelitis; Tumor Necrosis Factor-alpha	2018
Inflammation-Responsive Drug-Conjugated Dextran Nanoparticles Enhance Anti-Inflammatory Drug Efficacy. ACS applied materials & interfaces, 2018, Nov-28, Volume: 10, Issue:47 Topics: Animals; Anti-Inflammatory Agents; Dextrans; Drug Liberation; Dynamic Light Scattering; Hydrogen Peroxide; Hydrogen-Ion Concentration; Inflammation; Macrophages; Mice; Nanoparticles; Naproxen; Particle Size; RAW 264.7 Cells; Time Factors	2018
Liposomal Curcumin Enhances the Effect of Naproxen in a Rat Model of Migraine. Medical science monitor : international medical journal of experimental and clinical research, 2019, Jul-09, Volume: 25 Topics: Animals; Antioxidants; Curcumin; Disease Models, Animal; Drug Therapy, Combination; Inflammation; Male; Migraine Disorders; Naproxen; Oxidative Stress; Pain; Pain Measurement; Rats; Rats, Wistar	2019
Burrowing as a non-reflex behavioural readout for analgesic action in a rat model of sub-chronic knee joint inflammation. European journal of pain (London, England), 2014, Volume: 18, Issue:2 Topics: Analgesia; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Chronic Disease; Disease Models, Animal; Ibuprofen; Inflammation; Knee Joint; Male; Naproxen; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Reflex	2014
Nonselective inhibition of prostaglandin-endoperoxide synthases by naproxen ameliorates acute or chronic liver injury in animals. Experimental and molecular pathology, 2014, Volume: 96, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cyclooxygenase 1; Cyclooxygenase 2; End Stage Liver Disease; Hepatocytes; Inflammation; Male; Membrane Proteins; Naproxen; Necrosis; Rats; Rats, Inbred F344	2014
Designing a simple organic salt-based supramolecular topical gel capable of displaying in vivo self-delivery application. Chemical communications (Cambridge, England), 2014, Feb-18, Volume: 50, Issue:14 Topics: Administration, Topical; Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Carriers; Drug Design; Gels; Imiquimod; Inflammation; Male; Mice; Naproxen; Peptides; Salts	2014
Non-carboxylic analogues of aryl propionic acid: synthesis, anti-inflammatory, analgesic, antipyretic and ulcerogenic potential. Drug research, 2014, Volume: 64, Issue:9 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Carrageenan; Disease Models, Animal; Edema; Fever; Inflammation; Male; Mice; Naphthalenes; Naproxen; Pain; Propionates; Rats; Rats, Wistar; Ulcer	2014
The nitric oxide donor cis-[Ru(bpy)2(SO3)NO](PF6) increases gastric mucosa protection in mice--involvement of the soluble guanylate cyclase/K(ATP) pathway. Nitric oxide : biology and chemistry, 2015, Feb-15, Volume: 45 Topics: 2,2'-Dipyridyl; Animals; Cytokines; Ethanol; Gastric Mucosa; Guanylate Cyclase; Inflammation; KATP Channels; Mice; Naproxen; Nitrates; Nitric Oxide Donors; Nitrites; Organometallic Compounds; Peroxidase; Protective Agents; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase	2015
Anti-inflammatory and cytoprotective properties of hydrogen sulfide. Methods in enzymology, 2015, Volume: 555 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Gastrointestinal Tract; Gene Expression Regulation; Humans; Hydrogen Sulfide; Inflammation; Inflammatory Bowel Diseases; Intestinal Mucosa; Naproxen; Neurodegenerative Diseases; Pain; Protective Agents; Signal Transduction; Spinal Cord Injuries	2015
Deciphering the pathogenesis of NSAID enteropathy using proton pump inhibitors and a hydrogen sulfide-releasing NSAID. American journal of physiology. Gastrointestinal and liver physiology, 2015, Jun-15, Volume: 308, Issue:12 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Hepatobiliary Elimination; Hydrogen Sulfide; Inflammation; Intestinal Diseases; Male; Naproxen; Proton Pump Inhibitors; Rats, Wistar; RNA, Ribosomal, 16S	2015
Design, synthesis and QSAR studies on a series of 2, 5-disubstituted- 1,3,4-oxadiazole derivatives of diclofenac and naproxen for analgesic and anti-inflammatory activity. Medicinal chemistry (Shariqah (United Arab Emirates)), 2015, Volume: 11, Issue:8 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Design; Female; Inflammation; Male; Mice; Molecular Structure; Naproxen; Oxadiazoles; Pain; Pain Measurement; Quantitative Structure-Activity Relationship; Rats	2015
Resistance exercise and naproxen sodium: effects on a stable PGF2α metabolite and morphological adaptations of the upper body appendicular skeleton. Inflammopharmacology, 2015, Volume: 23, Issue:6 Topics: Adaptation, Physiological; Adult; Bones of Upper Extremity; Cyclooxygenase Inhibitors; Dinoprost; Double-Blind Method; Exercise; Humans; Inflammation; Male; Naproxen; Prostaglandin-Endoperoxide Synthases; Resistance Training; Young Adult	2015
Octadecylamine-Mediated Versatile Coating of CoFe2O4 NPs for the Sustained Release of Anti-Inflammatory Drug Naproxen and in Vivo Target Selectivity. ACS applied materials & interfaces, 2016, Apr-13, Volume: 8, Issue:14 Topics: Amines; Animals; Anti-Inflammatory Agents; Cobalt; Drug Delivery Systems; Ferric Compounds; Humans; Inflammation; Magnetite Nanoparticles; Mice; Naproxen; Particle Size; Rats; Spectroscopy, Fourier Transform Infrared; Surface Properties	2016
Hybrid Compounds Strategy in the Synthesis of Oleanolic Acid Skeleton-NSAID Derivatives. Molecules (Basel, Switzerland), 2016, Apr-12, Volume: 21, Issue:4 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Ibuprofen; Inflammation; Ketoprofen; Molecular Structure; Naproxen; Oleanolic Acid	2016
The hydrogen sulfide releasing compounds ATB-346 and diallyl trisulfide attenuate streptozotocin-induced cognitive impairment, neuroinflammation, and oxidative stress in rats: involvement of asymmetric dimethylarginine. Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:7 Topics: Allyl Compounds; Animals; Arginine; Cognitive Dysfunction; Hydrogen Sulfide; Inflammation; Inflammation Mediators; Male; Maze Learning; Naproxen; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Sulfides	2016
Inflammation: NSAIDs and cardiovascular risk in arthritis. Nature reviews. Cardiology, 2017, Volume: 14, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Celecoxib; Humans; Ibuprofen; Inflammation; Naproxen; Risk Factors	2017
Naproxen-PC: a GI safe and highly effective anti-inflammatory. Inflammopharmacology, 2009, Volume: 17, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Edema; Gastrointestinal Hemorrhage; Glycine max; Inflammation; Lecithins; Naproxen; Rats; Synovial Fluid	2009
Impact of chronic inflammation on the pharmacokinetic-pharmacodynamic relationship of naproxen. European journal of pain (London, England), 2010, Volume: 14, Issue:3 Topics: Animals; Dinoprostone; Dose-Response Relationship, Drug; Freund's Adjuvant; Inflammation; Naproxen; Rats; Rats, Sprague-Dawley; Thromboxane B2	2010
The effects of COX-2 inhibitor during osteogenic differentiation of bone marrow-derived human mesenchymal stem cells. Stem cells and development, 2010, Volume: 19, Issue:10 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Bone Marrow Cells; Celecoxib; Cell Differentiation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Gene Expression Regulation; Humans; Inflammation; Interleukin-1beta; Male; Mesenchymal Stem Cells; Middle Aged; Naproxen; Osteogenesis; Pyrazoles; RNA, Messenger; Sulfonamides; Young Adult	2010
Synergistic effect of the interaction between naproxen and citral on inflammation in rats. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Dec-15, Volume: 18, Issue:1 Topics: Acyclic Monoterpenes; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Synergism; Edema; Herb-Drug Interactions; Inflammation; Male; Monoterpenes; Naproxen; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Stomach Diseases	2010
APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation. PloS one, 2010, Jul-30, Volume: 5, Issue:7 Topics: Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ibuprofen; Immunohistochemistry; In Vitro Techniques; Inflammation; Male; Mice; Mice, Transgenic; Naproxen; Nerve Tissue Proteins; Neurogenesis; Nuclear Proteins	2010
Prevention of bleomycin-induced lung fibrosis in mice by a novel approach of parallel inhibition of cyclooxygenase and nitric-oxide donation using NCX 466, a prototype cyclooxygenase inhibitor and nitric-oxide donor. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 341, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Bleomycin; Collagen; Cyclooxygenase Inhibitors; Deoxyguanosine; Dinoprostone; Inflammation; Lung; Male; Mice; Mice, Inbred C57BL; Naproxen; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Peroxidase; Propionates; Prostaglandin-Endoperoxide Synthases; Pulmonary Fibrosis; Thiobarbiturates; Transforming Growth Factor beta	2012
Effects of non-steroidal antiinflammatory drugs on D-serine-induced oxidative stress in vitro. Drug and chemical toxicology, 2012, Volume: 35, Issue:4 Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Inflammation; Lipid Peroxidation; Malondialdehyde; Mefenamic Acid; Naproxen; Neuroprotective Agents; Oxidative Stress; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Serine	2012
A sulfated-polysaccharide fraction from seaweed Gracilaria birdiae prevents naproxen-induced gastrointestinal damage in rats. Marine drugs, 2012, Volume: 10, Issue:12 Topics: Animals; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Glutathione; Gracilaria; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Naproxen; Peroxidase; Polysaccharides; Rats; Rats, Wistar	2012
Bioactive phenolic derivatives from Acaena splendens methanol extract. Phytotherapy research : PTR, 2002, Volume: 16, Issue:6 Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Carrageenan; Catechin; Chromones; Edema; Female; Fever; Flavonoids; Glucosides; Guinea Pigs; Hindlimb; Inflammation; Kaempferols; Magnetic Resonance Spectroscopy; Male; Medicine, Traditional; Molecular Structure; Naproxen; Phenols; Phytotherapy; Plant Extracts; Rabbits; Rosaceae	2002
Inflammation 2003-Sixth World Congress. Nitric oxide and IBD. 2-6 August 2003, Vancouver, Canada. IDrugs : the investigational drugs journal, 2003, Volume: 6, Issue:9 Topics: Animals; British Columbia; Cyclooxygenase Inhibitors; Drugs, Investigational; Humans; Inflammation; Internationality; Irritable Bowel Syndrome; Naproxen; Nitric Oxide	2003
Lack of value of the naproxen test in the differential diagnosis of prolonged febrile illnesses. The American journal of medicine, 2003, Volume: 115, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Fever of Unknown Origin; Humans; Inflammation; Naproxen; Neoplasms	2003
Characterization of the chick carrageenan response. Brain research, 2003, Dec-24, Volume: 994, Issue:2 Topics: Analgesics, Opioid; Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Chickens; Cyclooxygenase Inhibitors; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Edema; Hyperalgesia; Inflammation; Morphine; Naproxen; Pain Measurement; Reaction Time; Time Factors	2003
Immunosuppressants, infection, and inflammation. Clinical immunology (Orlando, Fla.), 2004, Volume: 113, Issue:2 Topics: Arthralgia; Arthritis, Juvenile; Child, Preschool; Fever; Humans; Immunosuppressive Agents; Infections; Inflammation; Male; Methotrexate; Naproxen	2004
Nanoparticle based systemic gene therapy for lung cancer: molecular mechanisms and strategies to suppress nanoparticle-mediated inflammatory response. Technology in cancer research & treatment, 2004, Volume: 3, Issue:6 Topics: Animals; Anti-Inflammatory Agents; Cell Line; Dinoprostone; Female; Gene Expression; Genetic Therapy; Humans; Inflammation; Lung Neoplasms; Mice; Nanostructures; Naproxen; RNA-Binding Protein FUS; Signal Transduction; Transcription Factor AP-1; Transgenes	2004
Possible analgesic and anti-inflammatory interactions of aspartame with opioids and NSAIDs. Indian journal of experimental biology, 2005, Volume: 43, Issue:6 Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspartame; Carrageenan; Drug Interactions; Edema; Inflammation; Mice; Morphine; Naproxen; Narcotics; Pain; Pain Measurement; Pentazocine; Rats; Rats, Wistar; Sulfonamides; Sweetening Agents; Time Factors	2005
NMI-1182, a gastro-protective cyclo-oxygenase-inhibiting nitric oxide donor. Inflammopharmacology, 2005, Volume: 12, Issue:5-6 Topics: Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Edema; Gastric Mucosa; Humans; In Vitro Techniques; Inflammation; Male; Molecular Structure; Naphthalenes; Naproxen; Neutrophil Infiltration; Nitric Oxide Donors; Protective Agents; Rats; Rats, Sprague-Dawley; Vasodilation	2005
Effects of cyclooxygenase inhibition on canine coronary artery blood flow and thrombosis. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:1 Topics: Acetylcholine; Animals; Arachidonic Acid; Benzofurans; Carotid Arteries; Coronary Circulation; Coronary Vessels; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Epoprostenol; Inflammation; Ligation; Lipopolysaccharides; Naproxen; Platelet Aggregation; Propionates; Pyrazoles; Receptors, Epoprostenol; Sulfonamides; Thrombosis; Time Factors; Vasodilation; Vasodilator Agents	2008
Intradermal injection of Propionibacterium acnes: a model of inflammation relevant to acne. The Journal of investigative dermatology, 1984, Volume: 83, Issue:5 Topics: Acne Vulgaris; Animals; Benzoyl Peroxide; Disease Models, Animal; Erythromycin; Female; Fluocinolone Acetonide; Inflammation; Injections, Intradermal; Naproxen; Propionibacterium acnes; Pyrazoles; Rats; Rats, Inbred Strains; Tetracycline; Tretinoin	1984
Inhibition of PG production by MDL 035, a new non-steroidal non-acidic anti-inflammatory compound, in rat gastric mucosa and inflammatory exudate. Pharmacological research communications, 1984, Volume: 16, Issue:8 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Exudates and Transudates; Gastric Mucosa; Imidazoles; In Vitro Techniques; Indomethacin; Inflammation; Male; Naproxen; Prostaglandins; Prostaglandins E; Rats; Stomach Ulcer	1984
The mouse ear inflammatory response to topical arachidonic acid. The Journal of investigative dermatology, 1984, Volume: 82, Issue:4 Topics: Administration, Topical; Animals; Arachidonic Acid; Arachidonic Acids; Cell Division; DNA; Dose-Response Relationship, Drug; Ear, External; Edema; Erythema; Female; Inflammation; Mice; Naproxen; Prostaglandin-Endoperoxide Synthases; Skin; Vasodilation	1984
Non-steroidal anti-inflammatory agents in the horse. In practice, 1981, Volume: 3, Issue:5 Topics: Animals; Anti-Inflammatory Agents; Clonixin; Horse Diseases; Horses; Inflammation; Meclofenamic Acid; Naproxen; Phenylbutazone	1981
Effect of selective phosphodiesterase type IV inhibitor, rolipram, on fluid and cellular phases of inflammatory response. Inflammation, 1993, Volume: 17, Issue:3 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Cells, Cultured; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 4; Ear, External; Eicosanoids; Histamine Release; Humans; Imidazoles; Inflammation; Leukotriene B4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Monocytes; Nadolol; Naproxen; Neutrophils; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrazoles; Pyrrolidinones; Receptors, Adrenergic, beta; Rolipram; SRS-A; Thiazoles	1993
Antinociceptive effects of non-steroidal anti-inflammatory drugs in a rat model of unilateral hindpaw inflammation. European journal of pharmacology, 1994, May-12, Volume: 257, Issue:1-2 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Inflammation; Injections, Intramuscular; Male; Naphthaleneacetic Acids; Naproxen; Pain; Rats; Rats, Wistar	1994
Pharmacokinetics and pharmacodynamics of naproxen in acute experimental hepatitis. Arzneimittel-Forschung, 1993, Volume: 43, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Carrageenan; Chemical and Drug Induced Liver Injury; Galactosamine; Inflammation; Injections, Intravenous; Liver Function Tests; Liver Regeneration; Male; Naproxen; Protein Binding; Rats; Rats, Wistar	1993
Ultraviolet B-induced inflammatory cytokine production, in vivo: initial pharmacological characterization. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44 Suppl 2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dose-Response Relationship, Radiation; Inflammation; Mice; Mice, Inbred BALB C; Naproxen; Peroxidase; Pyrrolidinones; Rolipram; Tumor Necrosis Factor-alpha; Ultraviolet Rays	1995
The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation. Arthritis and rheumatism, 1996, Volume: 39, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chronic Disease; Disease Models, Animal; Drug Combinations; Exudates and Transudates; Female; Hydroxyurea; Inflammation; Leukotriene B4; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Naproxen; Prostaglandin-Endoperoxide Synthases; Quinolines; Time Factors; Zymosan	1996
Assessment of the antiexudative and antiproliferative activities of non-steroidal anti-inflammatory drugs in inflammatory models developed in rats by subcutaneous implantation of bacterial cell walls from the dental plaque. Inflammation, 1996, Volume: 20, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cell Division; Cell Wall; Child; Dental Plaque; DNA Replication; Duodenum; Edema; Exudates and Transudates; Granuloma; Growth Inhibitors; Humans; Ibuprofen; Indomethacin; Inflammation; Intestinal Mucosa; Naproxen; Rats; Sulindac	1996
Prevention by anti-LFA-1 of acute myoblast death following transplantation. Journal of immunology (Baltimore, Md. : 1950), 1997, Sep-01, Volume: 159, Issue:5 Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Apoptosis; beta-Galactosidase; Biomarkers; Cell Adhesion; Cell Death; Cell Line, Transformed; Fluoresceins; Genes, Reporter; Graft Rejection; Immunosuppressive Agents; Inflammation; Interleukin-1; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; Methylprednisolone; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred mdx; Mice, SCID; Muscle, Skeletal; Muscular Dystrophy, Animal; Naproxen; Necrosis; Neutrophils; Oxidative Stress; Peroxidase; Piroxicam; Radiation Chimera; Stem Cell Transplantation; Tacrolimus; Whole-Body Irradiation; Zymosan	1997
Pharmacoepidemiology of non-steroidal anti-inflammatory drug use in Nottingham general practices. Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:2 Topics: Adolescent; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Prescriptions; Family Practice; Humans; Ibuprofen; Inflammation; Medical Records Systems, Computerized; Middle Aged; Naproxen; Patient Compliance; Pharmacoepidemiology; United Kingdom	2000
Wound collagen deposition in rats: effects of an NO-NSAID and a selective COX-2 inhibitor. British journal of pharmacology, 2000, Volume: 129, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Celecoxib; Collagen; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Exudates and Transudates; Gastric Mucosa; Inflammation; Isoenzymes; Male; Membrane Proteins; Naproxen; Nitrates; Nitric Oxide Donors; Nitrites; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Thromboxanes; Wound Healing	2000
NO-naproxen modulates inflammation, nociception and downregulates T cell response in rat Freund's adjuvant arthritis. British journal of pharmacology, 2000, Volume: 130, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Dose-Response Relationship, Drug; Edema; Flow Cytometry; Hindlimb; Inflammation; Interleukin-1; Male; Naproxen; Nitric Oxide; Nociceptors; Pain; Pain Measurement; Rats; Rats, Inbred Lew; Receptors, Interleukin-2; T-Lymphocytes; Thymidine; Time Factors; Tumor Necrosis Factor-alpha	2000
Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals. Journal of neurochemistry, 2001, Volume: 76, Issue:6 Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoates; Cell Death; Cell Line; Cell Nucleus; Cell Survival; Dexamethasone; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Humans; Hydrocortisone; Imidazoles; Indomethacin; Inflammation; Mefenamic Acid; Naproxen; Neuroblastoma; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Rats; Tumor Cells, Cultured	2001
Mechanism of action of a new anti-inflammatory agent, naproxen (II). Effects of naproxen on activities of mucopolysaccharase, acid protease and collagenolytic enzymes in inflamed tissues. Japanese journal of pharmacology, 1976, Issue:1 Topics: Adenosine Triphosphatases; Animals; Anti-Inflammatory Agents; Exudates and Transudates; Female; Glucuronidase; Glycosaminoglycans; Granuloma; Inflammation; Lyases; Microbial Collagenase; Muramidase; Naphthaleneacetic Acids; Naproxen; Protease Inhibitors; Rats; Time Factors	1976
Penetration of naproxen and salicylate into inflammatory exudates in the rat. Annals of the rheumatic diseases, 1977, Volume: 36, Issue:3 Topics: Animals; Exudates and Transudates; Inflammation; Naphthaleneacetic Acids; Naproxen; Protein Binding; Rats; Serum Albumin, Radio-Iodinated; Sodium; Sodium Salicylate	1977
[Methoxypropriocin in the treatment of inflammatory and degenerative diseases of the locomotor system]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1976, Mar-01, Volume: 31, Issue:9 Topics: Adolescent; Adult; Aged; Humans; Inflammation; Middle Aged; Naphthaleneacetic Acids; Naproxen; Rheumatic Diseases	1976
Interaction studies of tilomisole, aspirin, and naproxen in acute and chronic inflammation with assessment of gastrointestinal irritancy in the rat. Agents and actions, 1992, Volume: 36, Issue:1-2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Benzimidazoles; Bone and Bones; Carrageenan; Connective Tissue; Drug Interactions; Edema; Gastrointestinal Diseases; Inflammation; Male; Naproxen; Rats; Rats, Sprague-Dawley	1992
Naproxen effects during acute inflammation produced by Staphylococcus aureus and by thinner structural study. Proceedings of the Western Pharmacology Society, 1992, Volume: 35 Topics: Animals; Inflammation; Male; Naproxen; Rats; Rats, Inbred Strains; Skin; Solvents; Staphylococcus aureus	1992
Arachidonic acid-induced inflammation: inhibition by dual inhibitor of arachidonic acid metabolism, SK&F 86002. Inflammation, 1987, Volume: 11, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Ibuprofen; Imidazoles; Inflammation; Male; Masoprocol; Mice; Mice, Inbred BALB C; Naproxen; Peritonitis; Piroxicam; Pyrazoles; Thiazoles	1987
Blood coagulation and bone metabolism: some characteristics of the bone resorptive effect of thrombin in mouse calvarial bones in vitro. Biochimica et biophysica acta, 1988, Mar-17, Volume: 964, Issue:3 Topics: Adrenal Cortex Hormones; Animals; Arachidonic Acid; Arachidonic Acids; Bone and Bones; Bone Matrix; Bone Resorption; Calcitonin; Calcium; In Vitro Techniques; Indomethacin; Inflammation; Lactates; Lysosomes; Meclofenamic Acid; Mice; Naproxen; Phosphates; Rats; Thrombin	1988
[Analgesic and anti-inflammatory treatment with sodium naproxen in odontostomatology]. Minerva stomatologica, 1988, Volume: 37, Issue:12 Topics: Adolescent; Adult; Aged; Drug Evaluation; Female; Humans; Inflammation; Male; Middle Aged; Naproxen; Pain, Postoperative; Surgery, Oral	1988
The metabolic cost of fever. Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:6 Topics: Animals; Body Temperature Regulation; Endotoxins; Energy Metabolism; Fever; Humans; Inflammation; Naproxen; Sheep	1987