naproxen has been researched along with Arthritis, Degenerative in 246 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 107 (43.50) | 18.7374 |
| 1990's | 56 (22.76) | 18.2507 |
| 2000's | 51 (20.73) | 29.6817 |
| 2010's | 27 (10.98) | 24.3611 |
| 2020's | 5 (2.03) | 2.80 |
| Authors | Studies |
|---|---|
| Bertenshaw, SR; Burton, EG; Carter, JS; Cogburn, JN; Collins, PW; Docter, S; Graneto, MJ; Gregory, SA; Isakson, PC; Koboldt, CM; Lee, LF; Malecha, JW; Miyashiro, JM; Penning, TD; Perkins, WE; Rogers, RS; Rogier, DJ; Seibert, K; Talley, JJ; Veenhuizen, AW; Yu, SS; Zhang, YY | 1 |
| Lane, NE; Lei, G; Li, X; Wei, J; Zeng, C; Zhang, Y | 1 |
| Choi, HK; Dubreuil, M; LaRochelle, MR; Lei, G; Lin, J; Lu, N; Tomasson, G; Wei, J; Wood, MJ; Zeng, C; Zhang, Y | 1 |
| Kang, CN; Kim, HJ; Kim, JH; Lee, S; Lee, WS; Moon, SH; Park, MS; Shin, SJ | 1 |
| Benito-Garzón, L; García-Fernández, L; Olmeda-Lozano, M; Pérez-Caballer, A; San Román, J; Vázquez-Lasa, B | 1 |
| Culbertson, MD; Galloway, J; Kadkoy, Y; Kanjilal, D; Lin, A; Moskonas, S; O'Connor, JP; Paglia, DN; Tompson, J; Wetterstrand, C | 1 |
| Raschle, J | 1 |
| Hyun, MK; Woo, Y | 1 |
| Borer, JS; Brennan, DM; Husni, ME; Libby, PA; Lincoff, AM; Lϋscher, TF; Menon, V; Nissen, SE; Solomon, DH; Wisniewski, LM; Yeomans, ND | 1 |
| Breivik, H | 1 |
| Beckerman, B; Borer, JS; Davey, DA; Fayyad, R; Flammer, AJ; Graham, DY; Husni, ME; Iorga, D; Krum, H; Libby, P; Lincoff, AM; Lüscher, TF; Menon, V; Nissen, SE; Ruschitzka, F; Solomon, DH; Wisniewski, LM; Yeomans, ND | 1 |
| Bao, W; Berger, MF; Borer, JS; Graham, DY; Husni, ME; Libby, P; Lincoff, AM; Lüscher, TF; Menon, V; Nissen, SE; Solomon, DH; Wang, Q; Wisniewski, LM; Wolski, KE; Yeomans, ND | 1 |
| Feng, X; Mei, H; Tian, M; Zhang, W | 1 |
| Bao, W; Borer, JS; Graham, DY; Husni, ME; Libby, P; Lincoff, AM; Lüscher, TF; Nissen, SE; Solomon, DH; Stevens, T; Vargo, J; Walker, C; Wang, Q; Wisniewski, LM; Wolski, KE; Yeomans, ND | 1 |
| Choi, HK; Dubreuil, M; Louie-Gao, Q; Neogi, T; Peloquin, CE; Zhang, Y | 1 |
| Husni, ME; Nissen, S; Paynter, N; Shao, M; Solomon, DH; Wolski, K | 1 |
| Aneja, A; Farkouh, ME; Gandhi, S; Greenberg, J; Iyengar, RL; Mosovich, S; Razzouk, L; Thorpe, K | 1 |
| Kean, WF; Leung, GJ; Rainsford, KD | 1 |
| Angiolillo, DJ; Datto, C; Raines, S; Yeomans, ND | 1 |
| Alaseem, AM; Aldebeyan, SA; Antoniou, J; Madiraju, P; Mwale, F; Noorwali, H | 1 |
| Choy, E; Howard, MA; Huggins, JP; Krause, K; Massat, NJ; O'Muircheartaigh, J; Sanders, D; Thacker, MA; Vennart, W; Williams, SC | 1 |
| Di Franco, M; Frati, L; Guarino, ML; Guzzo, MP; Massimi, I; Pulcinelli, FM; Temperilli, F; Valesini, G | 1 |
| Choi, SJ; Ji, JD; Kim, JH; Lee, YH; Seo, YH; Song, GG | 1 |
| Nurmohamed, MT | 1 |
| Bolla, M; Viappiani, S; Wallace, JL | 1 |
| Geusens, P | 1 |
| Beekman, M; Duquesroix, B; Fleming, R; Schnitzer, TJ; White, WB | 1 |
| Balas, M; Plakogiannis, R; Sinnett, M | 1 |
| Fort, JG; Goldstein, JL; Hochberg, MC; Hwang, C; Sostek, M; Zhang, Y | 1 |
| McLain, DA; Schumock, GT; Walton, SM | 1 |
| Estborn, L; Fort, JG; Sostek, MB; Vikman, K | 1 |
| Bakris, GL; Duquesroix, B; Frayssinet, H; Schnitzer, TJ; Weber, M; White, WB | 1 |
| Dzielska-Olczak, M | 1 |
| Akar, S; Akkoc, N; Can, G; Ceylan, I; Sari, I; Secil, M; Solmaz, D | 1 |
| Bansal, M; Happich, M; Klein, R; Wielage, R; Wilson, K | 1 |
| Goldstein, JL; Kent, JD; Kivitz, AJ; Palmer, RC; Recker, DP; Verburg, KM | 1 |
| Dixon, ME; Geba, GP; Johansson, G; Lisse, JR; Mollen, AJ; Perlman, M; Polis, AB; Schechtman, J; Shoemaker, JR; Skalky, CS | 1 |
| Gertz, BJ; Reicin, A; Sperling, RS; Weir, MR | 1 |
| Burian, M; Geisslinger, G | 1 |
| Chen, BY; Cheng, NN; Li, D; Shi, W; Wang, YM | 1 |
| Burke, TA; Michaud, K; Wolfe, F; Zhao, SZ | 1 |
| Averbuch, M; Katzper, M | 1 |
| Balestra, V; Molfetta, G; Monteforte, P; Rovetta, G | 2 |
| Hanauer, LB | 1 |
| Jenkinson, ML | 1 |
| Rusche, JM | 1 |
| Ehrsam, E; Farkouh, M; Gitton, X; Hawkey, CJ; Huels, J; Richardson, P | 1 |
| Summerton, N | 1 |
| Brabant, T; Fort, JG; Kivitz, A; Pitt, B; Simon, LS; Sowers, JR; van Ingen, H; Whelton, A; White, WB; Winer, N | 1 |
| Goldstein, JL; Mayne, TJ; Rabeneck, L; Rublee, DA; Vu, A | 1 |
| Braunstein, N; Polis, A | 1 |
| Fernandes, JC; Lajeunesse, D; Martel-Pelletier, J; Massicotte, F; Pelletier, JP | 1 |
| Agrawal, NM; Andrade-Ortega, L; Bello, AE; Eisen, GM; Fort, JG; Goldstein, JL; Hanrahan, PS; Levy, RA; Singh, G; Stenson, WF; Triadafilopoulos, G; Wallemark, C | 1 |
| Bergman, G; Curtis, SP; Ko, AT; Malmstrom, K; Mehta, A; Reginster, JY; Reicin, AS | 1 |
| Einecke, D | 1 |
| Abramson, SB; Chesebro, JH; Farkouh, ME; Fuster, V; Greenberg, JD; Hochman, JS; Jeger, RV; Kirshner, H; Lay, CL; Matchaba, PT; Mellein, B; Ramanathan, K; Ruland, S; Verheugt, FW | 1 |
| Jacobs, P; Loyd, M; Rublee, D | 1 |
| Gitton, X; Hawkey, CJ; Krammer, G; Matchaba, P; Mellein, B; Richard, D; Sallstig, P; Smalley, W; Stricker, K; Weinstein, WM | 1 |
| Amer, F; Cryer, B; Goldstein, JL; Hunt, B | 1 |
| Chu, SC; Hsieh, YS; Li, TJ; Lu, KH; Lue, KH; Yang, SF | 1 |
| Burdan, F; Przybylski, P; Sykut, J | 1 |
| Blum, D; Cunnington, M; Funk, MJ; Mander, A; Qizilbash, N; Webb, D; Weil, J | 1 |
| Fellmann, N; Reuteler, H; Stocker, H | 1 |
| Goldie, IF | 1 |
| Berry, H; Coquelin, JP; Gordon, A; Seymour, D | 1 |
| Caldwell, JR; Crain, D; Hoffmeister, RT; Kantrowitz, F; Lloyd, RJ; Nussdorf, RT; Repice, MR; Schmid, FR | 1 |
| Omdal, R | 1 |
| Clarke, TK; Mungavin, JM | 1 |
| Costa, L; Cozzolino, F; Marasco, E | 1 |
| Bentzen, L; Gjørup, T; Gylding-Sabroe, JP; Leopold, M; Marques, B; Ostrup, EL; Riis, P; Toldbod, M | 1 |
| Famaey, JP; Ginsberg, F | 3 |
| Currie, WJ; Dasgupta, PK; Diggins, JB; Glick, EN; Janke, PG; Sheikh, NA | 1 |
| Altman, RD | 1 |
| Daymond, TJ; Diffey, BL; Fairgreaves, H | 1 |
| Hawel, R | 1 |
| Bernacka, K; Sierakowski, S; Tytman, K | 1 |
| Brooks, PM; Cleland, LG; Haski, AL; Hempton, DB; Hills, LJ; Muller, JN | 1 |
| Børkje, B | 1 |
| Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM | 1 |
| Bailey, RR; Lynn, KL; Munn, E | 1 |
| Blechman, WJ | 1 |
| Bach-Andersen, R; Persson, B; Telhag, H | 1 |
| Hybbinette, CH | 1 |
| Kogstad, O | 1 |
| Dieppe, P; Doyle, D; Jacoby, R | 1 |
| English, JR; Liyanage, SP; Macauley, DI | 1 |
| Stambuk, B; Zenić, N | 1 |
| Crone, M; Geimer, R | 1 |
| Carion, J; Debelle, M; Van der Mijnsbrugge, J | 1 |
| Brooks, PM; Dougan, MA; Hills, LJ; Smith, PJ; Thomas, D | 1 |
| Lorber, M; Nahir, M; Schapira, D; Scharf, Y | 1 |
| Placheta, P; Siegmeth, W | 1 |
| Pathy, MS | 1 |
| Cytryn, E; Pintens, H; Verbruggen, LA | 1 |
| Pavelka, K; Susta, A | 1 |
| Martel-Pelletier, J; Pelletier, JP | 1 |
| Aleotti, A; Alvisi, V; Caselli, M; DeCarlo, L; LaCorte, R; Ruina, M; Trevisani, L; Trotta, F | 1 |
| Geis, GS | 1 |
| Ardia, A; Baggio, A; Cornelli, U; Franchini, S | 1 |
| Bennett, R; Caldron, P; Koepp, R; Mitchell, C; Roth, SH; Swenson, C | 1 |
| Caldwell, JR; Roth, SH | 1 |
| Jennings, MB | 1 |
| Azulay, JP; Blin, O; Daumen-Legré, V; Serratrice, G | 1 |
| Cumming, G; Lewis, B; Lewis, D | 1 |
| Brocks, DR; Skeith, KJ | 1 |
| Consoli, G; Covelli, M; Di Matteo, L; La Montagna, G; Marcolongo, R; Pipitone, V; Tirri, G | 1 |
| Bacon, P | 1 |
| Alarcón, GS; Brooks, RH; Clegg, DO; Egger, MJ; Field, EH; Neuner, R; Skosey, JL; Ward, JR; Williams, HJ; Willkens, RF | 1 |
| Cloutier, JM; DiBattista, J; Loose, LD; Martel-Pelletier, J; McCollum, R; Pelletier, JP | 1 |
| Ersmark, H; Fagertun, H; Høyeraal, HM; Ingemann-Hansen, T; Rönn, O | 1 |
| Bruyn, GA; Geis, GS; Melo Gomes, JA; Roth, SH; Woods, EM; Zeeh, J | 1 |
| DeLapp, RE; Eversmeyer, W; Jensen, CP; Poland, M | 1 |
| DeLapp, RE; Morgan, GJ; Poland, M | 1 |
| DeLapp, RE; Lister, BJ; Poland, M | 1 |
| Glazer, PA; Lane, N; Mahmud, F; Mow, VC; Ratcliffe, A; Rosenwasser, MP; Saed-Nejad, F | 1 |
| Badurski, J; Jeziernicka, E; Naruszewicz, K; Racewicz, A | 1 |
| Atkinson, JP | 1 |
| Schiff, MH | 1 |
| Ardizzone, S; Bianchi Porro, G; Brunetti, G; Frizziero, L; Grandinetti, G; Menegatti, M; Miglioli, M; Montrone, F; Petrillo, M; Vaira, D | 1 |
| Bjarnason, I; Hayllar, J | 1 |
| Constantine, G; Schnitzer, TJ | 1 |
| Bjarnason, I; Hayllar, J; Macpherson, A; Rotman, H; Schupp, J | 1 |
| Bianchi Porro, G; Lazzaroni, M; Petrillo, M | 1 |
| Bowdler, J; Frerick, H; Kornasoff, D; Montull, E | 1 |
| Fox, SM; Johnston, SA | 1 |
| McKenna, F | 1 |
| Schnitzer, TJ | 1 |
| Geis, GS; Hubbard, RC; Isakson, PC; Lanza, FL; Lipsky, PE; Schwartz, BD; Simon, LS; Talwalker, S | 1 |
| Christophidis, N; Kwiatek, R; Scharf, S; Ugoni, A | 1 |
| Altman, RD; Moskowitz, R | 1 |
| Duval, N; Fernandes, JC; Martel-Pelletier, J; Mineau, F; Pelletier, JP | 1 |
| Karateev, DE | 1 |
| Kamin, M; Olson, WH; Schnitzer, TJ | 1 |
| Dorak, F; Fetil, E; Güneş, T; Izler, F; Ozkan, S | 1 |
| Bensen, WG; Fiechtner, JJ; Geis, GS; Hubbard, RC; Isakson, PC; McMillen, JI; Verburg, KM; Woods, EM; Yu, SS; Zhao, WW | 1 |
| Callahan, LF; Cummins, P; Pincus, T; Swearingen, C | 1 |
| DeBrota, DJ; Gitter, BD; Goldstein, DJ; Iyengar, S; Todd, LE; Wang, O | 1 |
| Agrawal, NM; Bensen, WG; Burke, TA; Geis, GS; Makuch, RW; Maurath, CJ; Zabinski, RA; Zhao, SZ | 1 |
| Dedhiya, SD; Espinoza, L; Lisse, J; Osterhaus, JT; Zhao, SZ | 1 |
| Agarwal, V; Liu, P; Shah, A; Sundaresan, P; Woodruff, M | 1 |
| Tive, L | 1 |
| Huskisson, EC | 1 |
| Di Battista, JA; Fahmi, H; He, Y; Martel-Pelletier, J; Pelletier, JP; Zhang, M | 1 |
| Fernandes, JC; Hilal, G; Lajeunesse, D; Martel-Pelletier, J; Massicotte, F; Pelletier, JP | 1 |
| Ehrlich, JC; Korff, KJ; Kriegel, W; Lehnhardt, K; Macciocchi, A; Moresino, C; Pawlowski, C | 1 |
| Barr, E; Gertz, BJ; Konstam, MA; Reicin, A; Shapiro, D; Sperling, RS; Weir, MR | 1 |
| Bandyopadhyay, P; Butler, JV; Patel, CU | 1 |
| Bisogno, S; Di Martino, S; Fioravanti, A; Marcolongo, R; Oldani, V; Scotti, A; Storri, L | 1 |
| Ausiello, JC; Stafford, RS | 1 |
| Shaughnessy, AF | 1 |
| Bevirt, T; Eisen, G; Kivitz, A; Recker, DP; Zhao, WW | 1 |
| Mayhew, SR | 1 |
| Lewis, JR | 1 |
| Blechman, W; Lorber, A; Multz, C; Roth, S | 1 |
| Siraux, P | 1 |
| Sfikakis, P; Tsachalos, P | 1 |
| Blechman, W; Boncaldo, GL; Hoffmeister, RT; Lockie, LM; Multz, C; Willkens, R | 1 |
| Lepistö, PV; Vainio, JT | 1 |
| Car, A; Jajić, I; Krampac, I; Vitaus, M; Zenić, N; Zivković, M | 1 |
| Lussier, A; Melton, JW; Multz, C; Neustadt, D; Ward, JR | 1 |
| Rooney, GI | 1 |
| Brémová, A; Kańková, D; Malecek, J; Pavelka, K; Susta, A; Vojtísek, O | 1 |
| Ito, T; Mori, E; Muroga, T; Nakajima, A; Tanaka, S | 1 |
| Katona, G | 1 |
| Barnes, CG; Clarke, AK; Cochrane, GM; Eade, AW; Goodman, HV; Misra, HN; Stoppard, M | 1 |
| Aagaard, J | 1 |
| Clarke, AK | 1 |
| Binzus, G | 1 |
| Aeidler, H | 1 |
| Rau, R | 1 |
| Biehl, G | 1 |
| Adamska-Dyniewska, H; Bala, T; Chojnacki, J; Chojnowska-Jezierska, J; Goch, JH; Tkaczewski, W | 1 |
| Bernstein, RM; Coppock, JS; Davies, PG; Doyle, DV; Huskisson, EC; Platt, PR; Scott, DL; Witherington, RH; Wojtulewski, JA | 1 |
| Andersen, LA; Barslev, J; Christensen, KA; Ibfelt, HH; Jensen, ON; Kjønniksen, T; Lehn, OF; Mjølstad, W; Solheim, L; Wiig, G | 1 |
| Fleischmann, RM | 1 |
| Beaulieu, A; Bellamy, N; Bombardier, C; Campbell, J; Huang, S; Kraag, G; Ménard, HA; Russell, AS; Tannenbaum, H; Willans, M | 1 |
| Beaulieu, A; Bellamy, N; Bombardier, C; Esdaile, J; Huang, S; Jovaisas, AV; Khanna, VN; Kraag, G; Mehta, DM; Ménard, HA | 1 |
| Gur-Lavi, M; Sanal, SM | 1 |
| Downing, ME; Ellis, R; Khong, TK; Miller, AJ; Patchett, I; Trayner, J | 1 |
| Hundal, O; Husby, G; Rugstad, HE | 1 |
| Brørs, O; Kvien, TK; Nordby, J; Rognstad, S; Staff, PH | 1 |
| Azzolini, V; Caruso, I; Cazzola, M; Montrone, F; Vaiani, G | 1 |
| Russell, RI | 1 |
| Tang, FS | 1 |
| Bridges, AJ; Diaz-Arias, AA; Marshall, JB | 1 |
| Waterworth, RF; Waterworth, SM | 1 |
| Blin, O; Lafforgue, P; Pailhous, J; Serratrice, G | 1 |
| Platt, PN | 1 |
| Karbowski, A | 1 |
| Grattan, CE | 1 |
| Biasi, G; Cataldi, V; Fioravanti, A; Giordano, N; Marcolongo, R; Vaccai, D | 1 |
| Bosio, S; Lacovacci, F; Venturino, G | 1 |
| Colgan, BV; Devane, JG; Kelly, JG; Kinney, CD; Mulligan, S | 1 |
| Domljan, Z; Dürrigl, T; Pucar, I; Vrhovac, B | 1 |
| Giercksky, KE; Huseby, G; Rugstad, HE | 1 |
| Constable, TJ; Lodwick, R; Sinha, SK; Wallis, PJ | 1 |
| Faulkner, G; Langman, M; Somerville, K | 1 |
| Alho, A; Holme, I; Jaer, O; Slungaard, U | 1 |
| Bruno, R; Cano, JP; Cunci, S; Guego, M; Iliadis, A; Jullien, I; Pinhas, H | 1 |
| Frankhof, W | 1 |
| Goodman, LA; Pisko, EJ; Rice, D; Strader, K; White, R | 1 |
| Roth, SH | 1 |
| Poiley, JE | 1 |
| Bockow, BI; Box, P; Brodsky, AL; Burch, FX; Collins, RL; Fleischmann, RM; Keller, MI; Lipani, JA; Pisko, EJ; Poiley, JE | 1 |
| Caruso, I; Pietrogrande, V | 1 |
| Goldberg, MA | 1 |
| Giercksky, KE; Herland, OB; Holme, I; Husby, G; Rugstad, HE | 2 |
| Altman, R | 1 |
| Ward, JR | 1 |
| Backhouse, CI | 1 |
| Garber, EK; Guth, PH; Silpa, ML; Stolz, A | 1 |
| Giercksky, KE; Herland, OB; Holme, I; Hundal, O; Husby, G; Rugstad, HE | 1 |
| Rugstad, HE | 1 |
| Meisel, AD | 1 |
| Husby, G | 1 |
| Angelini, M; Carrabba, M; Chevallard, M; Mele, G | 1 |
| Deal, CL; Moskowitz, RW | 1 |
| Geczy, M; Peltier, L; Wolbach, R | 1 |
| Boussina, I; Vischer, TL | 1 |
| Cardoe, N; Hart, FD | 1 |
| De Jager, JP; Fleming, A; White, R | 1 |
| Lethbridge, J; Littler, T; Martin, N; McVerry, RM; Mukerjee, SK; Orme, ML; Sibeon, R; Tallis, R | 1 |
| Daehler, MH | 1 |
| Benincà, G; Cattoni, C; de Candia, R; Genco, G; Trombetta, N | 1 |
| Caspi, I; Ezra, E; Horoszowsky, H; Lin, E; Weiss, J | 1 |
| Berry, H; Nicholls, A | 1 |
| Brogden, RN; Sorkin, EM | 1 |
| Brackertz, D; Rohde, HJ; Schönmehl, W; Sekker, W | 1 |
| Vetter, G | 1 |
| Gordin, A; Nuutila, J; Sotka, S | 1 |
| Björkenheim, JM; Helland, J; Peltonen, J | 1 |
| Bassi, GP; Borghi, C; Camarri, E; Cocco, F; Francucci, BM; Giannini, R; Giordano, N; Marcolongo, R; Mordini, M; Neri, D | 1 |
| Hodge, RH | 1 |
| Macauley, D | 1 |
| Caldwell, JR | 1 |
21 review(s) available for naproxen and Arthritis, Degenerative
| Article | Year |
|---|---|
Gastrointestinal safety of etoricoxib in osteoarthritis and rheumatoid arthritis: A meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Humans; Naproxen; Osteoarthritis; Pyridines; Randomized Controlled Trials as Topic; Sulfones | 2018 |
Osteoarthritis of the hand II: chemistry, pharmacokinetics and pharmacodynamics of naproxen, and clinical outcome studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Hand; Humans; Naproxen; Osteoarthritis | 2014 |
Relative efficacy and tolerability of etoricoxib, celecoxib, and naproxen in the treatment of osteoarthritis : A Bayesian network meta-analysis of randomized controlled trials based on patient withdrawal.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Bayes Theorem; Celecoxib; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Etoricoxib; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Outcome Assessment, Health Care; Proportional Hazards Models; Pyridines; Randomized Controlled Trials as Topic; Sulfones; Treatment Outcome | 2016 |
Naproxcinod, a new cyclooxygenase-inhibiting nitric oxide donator (CINOD).
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Humans; Naproxen; Nitric Oxide Donors; Osteoarthritis | 2009 |
[Cyclooxygenases inhibitors and other compounds with antiinflammatory potential in osteoarthrosis--part II].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyclooxygenase Inhibitors; Drug Interactions; Humans; Naproxen; Nitric Oxide Donors; Osteoarthritis | 2011 |
Cost-effectiveness of duloxetine in chronic low back pain: a Quebec societal perspective.
Topics: Age Factors; Aged; Amitriptyline; Analgesics; Cardiovascular Diseases; Celecoxib; Chronic Disease; Clinical Trials as Topic; Cost-Benefit Analysis; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Hydromorphone; Low Back Pain; Markov Chains; Middle Aged; Models, Economic; Naproxen; Ontario; Osteoarthritis; Outcome Assessment, Health Care; Oxycodone; Pregabalin; Pyrazoles; Quality-Adjusted Life Years; Quebec; Sulfonamides; Thiophenes | 2013 |
Selective COX-2 inhibition and cardiovascular effects: a review of the rofecoxib development program.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Blood Pressure; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Drug Therapy, Combination; Endothelium, Vascular; Epoprostenol; Humans; Isoenzymes; Lactones; Membrane Proteins; Models, Animal; Naproxen; Osteoarthritis; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Randomized Controlled Trials as Topic; Sulfones; Thrombosis; Thromboxanes | 2003 |
[Clinical pharmacology of the selective COX-2 inhibitors].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Clinical Trials, Phase III as Topic; Cyclooxygenase Inhibitors; Diclofenac; Humans; Isoxazoles; Lactones; Naproxen; Osteoarthritis; Pain; Pain, Postoperative; Placebos; Pyrazoles; Sulfonamides; Sulfones | 2003 |
[Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; China; Diclofenac; Humans; Ibuprofen; Meloxicam; Nabumetone; Naproxen; Osteoarthritis; Oxaprozin; Propionates; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiazoles | 2003 |
Naproxcinod: AZD 3582, HCT 3012, naproxen nitroxybutylester, nitronaproxen, NO-naproxen.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Humans; Naproxen; Nitric Oxide Donors; Osteoarthritis; Terminology as Topic; Treatment Outcome | 2007 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin | 1984 |
Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin.
Topics: Adult; Animals; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Female; Gastric Mucosa; Gout; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Phenylacetates; Platelet Aggregation; Rheumatic Diseases; Spondylitis, Ankylosing; Ulcer | 1980 |
Pharmacokinetic optimisation of the treatment of osteoarthritis.
Topics: Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Female; Humans; Male; Naproxen; Obesity; Osteoarthritis | 1994 |
Use of carprofen for the treatment of pain and inflammation in dogs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamic Acid; Meloxicam; Naproxen; Osteoarthritis; Pain; Phenylbutazone; Piroxicam; Thiazines; Thiazoles | 1997 |
Non-NSAID pharmacologic treatment options for the management of chronic pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dextropropoxyphene; Humans; Ibuprofen; Naproxen; Osteoarthritis; Pain; Tramadol; Treatment Outcome | 1998 |
[Brufen on the eve of the 21st century].
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Gout Suppressants; Humans; Ibuprofen; Middle Aged; Naproxen; Osteoarthritis; Piroxicam; Retrospective Studies; Rheumatic Diseases; Time Factors | 1998 |
Celecoxib clinical profile.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; In Vitro Techniques; Isoenzymes; Kidney Diseases; Membrane Proteins; Middle Aged; Naproxen; Osteoarthritis; Pain; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Treatment Outcome | 2000 |
Nimesulide, a balanced drug for the treatment of osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diclofenac; Etodolac; Humans; Naproxen; Osteoarthritis; Stomach Diseases; Sulfonamides; Treatment Outcome | 2001 |
Cardiovascular thrombotic events in controlled, clinical trials of rofecoxib.
Topics: Aged; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Chronic Disease; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Clinical Trials, Phase IV as Topic; Comorbidity; Cyclooxygenase 1; Cyclooxygenase 2; Female; Humans; Isoenzymes; Lactones; Low Back Pain; Male; Membrane Proteins; Middle Aged; Naproxen; Osteoarthritis; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Randomized Controlled Trials as Topic; Risk; Sulfones; Thrombosis | 2001 |
A global safety evaluation of etodolac.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Etodolac; Female; Humans; Indoleacetic Acids; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam | 1989 |
Tiaprofenic acid. A review of its pharmacological properties and therapeutic efficacy in rheumatic diseases and pain states.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Blood Platelets; Drug Evaluation; Drug Interactions; Humans; Indomethacin; Intestinal Absorption; Intestinal Mucosa; Kinetics; Naproxen; Osteoarthritis; Pain; Propionates; Prostaglandins; Rheumatic Diseases; Tissue Distribution | 1985 |
155 trial(s) available for naproxen and Arthritis, Degenerative
| Article | Year |
|---|---|
A comparative study of the efficacy of NAXOZOL compared to celecoxib in patients with osteoarthritis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Double-Blind Method; Esomeprazole; Female; Gastrointestinal Diseases; Humans; Male; Naproxen; Osteoarthritis; Pain; Prospective Studies; Surveys and Questionnaires | 2020 |
Topics: Adult; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Naproxen; Osteoarthritis; Proton Pump Inhibitors; Survival Analysis; United States; United States Food and Drug Administration | 2017 |
The Risk of Major NSAID Toxicity with Celecoxib, Ibuprofen, or Naproxen: A Secondary Analysis of the PRECISION Trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis | 2017 |
Differential blood pressure effects of ibuprofen, naproxen, and celecoxib in patients with arthritis: the PRECISION-ABPM (Prospective Randomized Evaluation of Celecoxib Integrated Safety Versus Ibuprofen or Naproxen Ambulatory Blood Pressure Measurement)
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Pressure; Celecoxib; Coronary Artery Disease; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Hypertension; Ibuprofen; Male; Naproxen; Osteoarthritis; Prospective Studies | 2017 |
Differences in Safety of Nonsteroidal Antiinflammatory Drugs in Patients With Osteoarthritis and Patients With Rheumatoid Arthritis: A Randomized Clinical Trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Double-Blind Method; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Kidney Diseases; Male; Middle Aged; Naproxen; Osteoarthritis; Risk Factors; Treatment Outcome | 2018 |
Randomised clinical trial: gastrointestinal events in arthritis patients treated with celecoxib, ibuprofen or naproxen in the PRECISION trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Aspirin; Celecoxib; Double-Blind Method; Drug Therapy, Combination; Esomeprazole; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Treatment Outcome | 2018 |
Derivation and Validation of a Major Toxicity Risk Score Among Nonsteroidal Antiinflammatory Drug Users Based on Data From a Randomized Controlled Trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Reproducibility of Results; Risk Assessment; Risk Factors | 2019 |
NSAIDs are associated with lower depression scores in patients with osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Depression; Double-Blind Method; Drug Administration Schedule; Female; Humans; Ibuprofen; Logistic Models; Male; Middle Aged; Multivariate Analysis; Naproxen; Osteoarthritis; Psychological Tests; Pyrazoles; Sulfonamides; Surveys and Questionnaires; Treatment Outcome | 2013 |
Impact of concomitant low-dose aspirin on the safety and tolerability of naproxen and esomeprazole magnesium delayed-release tablets in patients requiring chronic nonsteroidal anti-inflammatory drug therapy: an analysis from 5 Phase III studies.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Aspirin; Delayed-Action Preparations; Double-Blind Method; Esomeprazole; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Naproxen; Osteoarthritis | 2014 |
Pharmacologic modulation of hand pain in osteoarthritis: a double-blind placebo-controlled functional magnetic resonance imaging study using naproxen.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Carpometacarpal Joints; Cross-Over Studies; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Pain Measurement | 2015 |
Effects of the cyclooxygenase inhibiting nitric oxide donator naproxcinod versus naproxen on systemic blood pressure in patients with osteoarthritis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Comorbidity; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Naproxen; Nitric Oxide Donors; Osteoarthritis | 2009 |
Clinical trial: the incidence of NSAID-associated endoscopic gastric ulcers in patients treated with PN 400 (naproxen plus esomeprazole magnesium) vs. enteric-coated naproxen alone.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Esomeprazole; Humans; Incidence; Magnesium; Middle Aged; Naproxen; Osteoarthritis; Stomach Ulcer; Tablets, Enteric-Coated; Treatment Outcome; Young Adult | 2010 |
Long-term safety of naproxen and esomeprazole magnesium fixed-dose combination: phase III study in patients at risk for NSAID-associated gastric ulcers.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Dosage Forms; Drug Combinations; Esomeprazole; Female; Humans; Magnesium Compounds; Male; Middle Aged; Naproxen; Osteoarthritis; Risk Factors; Stomach Ulcer; Time Factors | 2011 |
Effects of naproxcinod on blood pressure in patients with osteoarthritis.
Topics: Aged; Blood Pressure; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Nitric Oxide Donors; Osteoarthritis; Treatment Outcome | 2011 |
The effect of non-steroidal anti-inflammatory drugs on the endothelial function of patients with osteoarthritis in short term.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Brachial Artery; Cyclooxygenase Inhibitors; Diclofenac; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Naproxen; Nitroglycerin; Osteoarthritis; Prospective Studies; Treatment Outcome; Vasodilation | 2012 |
A comparison of the upper gastrointestinal mucosal effects of valdecoxib, naproxen and placebo in healthy elderly subjects.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Gastrointestinal Diseases; Humans; Intestinal Mucosa; Isoxazoles; Naproxen; Osteoarthritis; Pain; Risk Factors; Sulfonamides | 2003 |
Gastrointestinal tolerability and effectiveness of rofecoxib versus naproxen in the treatment of osteoarthritis: a randomized, controlled trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Hypertension; Lactones; Male; Middle Aged; Naproxen; Osteoarthritis; Prospective Studies; Sulfones | 2003 |
Assessment of visual analog versus categorical scale for measurement of osteoarthritis pain.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Controlled Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Pain Measurement; Retrospective Studies | 2004 |
A two-year study of chondroitin sulfate in erosive osteoarthritis of the hands: behavior of erosions, osteophytes, pain and hand dysfunction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chondroitin Sulfates; Disease Progression; Drug Therapy, Combination; Female; Finger Joint; Hand Deformities, Acquired; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Prospective Studies; Radiography; Severity of Illness Index; Treatment Outcome | 2004 |
Therapeutic arthritis research and gastrointestinal event trial of lumiracoxib - study design and patient demographics.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Health Status; Humans; Ibuprofen; Isoenzymes; Membrane Proteins; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Peptic Ulcer; Prognosis; Prostaglandin-Endoperoxide Synthases; Risk Factors | 2004 |
The Effects of cyclooxygenase-2 inhibitors and nonsteroidal anti-inflammatory therapy on 24-hour blood pressure in patients with hypertension, osteoarthritis, and type 2 diabetes mellitus.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Blood Pressure Determination; Celecoxib; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Hypertension; Lactones; Male; Middle Aged; Naproxen; Osteoarthritis; Probability; Pyrazoles; Risk Assessment; Sulfonamides; Sulfones; Treatment Outcome | 2005 |
Valdecoxib is associated with improved dyspepsia-related health compared with nonspecific NSAIDs in patients with osteoarthritis or rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Dyspepsia; Female; Humans; Ibuprofen; Isoxazoles; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Patient Satisfaction; Placebos; Quality of Life; Sulfonamides; Treatment Outcome; Upper Gastrointestinal Tract | 2005 |
Celecoxib versus naproxen and diclofenac in osteoarthritis patients: SUCCESS-I Study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Pyrazoles; Severity of Illness Index; Sulfonamides | 2006 |
Evaluation of the efficacy and safety of etoricoxib compared with naproxen in two, 138-week randomised studies of patients with osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Double-Blind Method; Etoricoxib; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Pyridines; Sulfones; Time Factors; Treatment Outcome | 2007 |
Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Heart Defects, Congenital; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis | 2007 |
Effect of risk factors on complicated and uncomplicated ulcers in the TARGET lumiracoxib outcomes study.
Topics: Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Diclofenac; Duodenal Ulcer; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Risk Factors; Risk Reduction Behavior; Stomach Ulcer | 2007 |
Celecoxib plus aspirin versus naproxen and lansoprazole plus aspirin: a randomized, double-blind, endoscopic trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Celecoxib; Confidence Intervals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Duodenal Ulcer; Endoscopy, Gastrointestinal; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Incidence; Lansoprazole; Male; Middle Aged; Naproxen; Osteoarthritis; Proton Pump Inhibitors; Pyrazoles; Retrospective Studies; Risk Factors; Stomach Ulcer; Sulfonamides; United States | 2007 |
Piroxicam and naproxen in osteoarthritis: a clinical comparison.
Topics: Adult; Aged; Humans; Middle Aged; Naproxen; Osteoarthritis; Piroxicam | 1981 |
Antrafenine, naproxen and placebo in osteoarthritis: a comparative study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Kinetics; Male; Naproxen; Osteoarthritis; Piperazines | 1983 |
Four-way, multicenter, crossover trial of ibuprofen, fenoprofen calcium, naproxen, and tolmetin sodium in osteoarthritis: comparative clinical profiles.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Female; Fenoprofen; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Phenylpropionates; Pyrroles; Tolmetin | 1983 |
[Naprosyn (naproxen) versus Donobid (diflunisal) in the treatment of osteoarthrosis of the hip and knee. A long-term study].
Topics: Adult; Aged; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Hip Joint; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Random Allocation; Salicylates | 1983 |
A multi-centre study of tiaprofenic acid ('Surgam') and five comparative drugs in rheumatoid arthritis and osteoarthritis in general practice.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Patient Compliance; Propionates; Sex Factors; Thiazines | 1983 |
[The clinical efficacy and tolerance of a new anti-inflammatory agent, carprofen, in osteoarthritis. Comparative double-blind study with naproxen].
Topics: Adult; Aged; Anti-Inflammatory Agents; Carbazoles; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis | 1983 |
[The effect of naproxen compared with that of traction in patients with osteoarthrosis of the hip. A single-blind controlled study].
Topics: Aged; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Traction | 1983 |
A double-blind, parallel trial of oxaprozin versus naproxen in the treatment of osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Oxaprozin; Propionates | 1984 |
A study of naproxen and ibuprofen in patients with osteoarthritis seen in general practice. The Manchester General Practitioner Group.
Topics: Aged; Clinical Trials as Topic; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis | 1984 |
A multi-centre study of sulindac versus naproxen in the treatment of elderly osteoarthritic patients.
Topics: Aged; Clinical Trials as Topic; Female; Humans; Indenes; Male; Naproxen; Osteoarthritis; Sulindac; Time Factors | 1984 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin | 1984 |
Evaluation of a single daily dose of naproxen in osteoarthritis.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Random Allocation | 1982 |
[Diflunisal or naproxen in arthrosis. A double-blind study].
Topics: Adult; Aged; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Hip Joint; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Random Allocation; Salicylates | 1982 |
Crossover comparison of benoxaprofen and naproxen in osteoarthritis.
Topics: Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents; Benzoxazoles; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Patient Compliance; Propionates; Salicylates; Time Factors | 1980 |
A double-blind comparative evaluation of tolmetin versus naproxen in osteoarthritis.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Naproxen; Osteoarthritis; Pain; Pyrroles; Tolmetin | 1981 |
Piroxicam and naproxen in the treatment of osteoarthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam; Pyridines; Thiazines | 1981 |
Double blind crossover trial of piroxicam and naproxen in the treatment of osteoarthritis of hip and knee.
Topics: Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Female; Hip Joint; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam; Pyridines; Thiazines | 1981 |
Arthritis: anti-inflammatory drugs in practice.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Apazone; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Fenoprofen; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Random Allocation | 1981 |
Naproxen and sulindac in the treatment of osteoarthritis of the hip and knee.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Female; Hip Joint; Humans; Indenes; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Random Allocation; Sulindac | 1981 |
[Comparative double-blind trial of diclophenac-sodium and naproxen in hip arthrosis].
Topics: Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Hip Joint; Humans; Middle Aged; Naproxen; Osteoarthritis; Phenylacetates | 1981 |
[Results of an open study and a controlled comparative study of feprazone and naproxen in patients with rheumatoid arthritis or osteoarthrosis (author's transl)].
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Feprazone; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Phenylbutazone | 1981 |
Indoprofen. Short-term double-blind cross-over study in patients with osteoarthritis of the hip.
Topics: Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Digestive System; Double-Blind Method; Female; Hip Joint; Humans; Indoprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Phenylpropionates | 1981 |
Naproxen and diflunisal in osteoarthrosis.
Topics: Aged; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Humans; Male; Naproxen; Osteoarthritis; Salicylates | 1982 |
A comparative study of naproxen with diclofenac sodium in osteoarthrosis of the knees.
Topics: Adult; Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Phenylacetates | 1982 |
[Double-blind comparative trial of lonazolac-Ca versus naproxen in spinal osteoarthrosis, coxarthrosis and gonarthrosis (author's transl)].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Elbow Joint; Female; Hip Joint; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pyrazoles; Spinal Diseases | 1982 |
Double-blind crossover study of nabumetone versus naproxen in the treatment of osteoarthritis of the knee and hip.
Topics: Anti-Inflammatory Agents; Butanones; Double-Blind Method; Drug Tolerance; Hip Joint; Humans; Knee Joint; Locomotion; Nabumetone; Naproxen; Osteoarthritis | 1982 |
Double-blind crossover study of nabumetone versus naproxen in the treatment of osteoarthritis.
Topics: Aged; Anti-Inflammatory Agents; Butanones; Double-Blind Method; Drug Tolerance; Female; Hip Joint; Humans; Knee Joint; Locomotion; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Random Allocation; Spinal Osteophytosis | 1982 |
Efficacy and upper GI safety of diclofenac/misoprostol, piroxicam and naproxen in patients with osteoarthritis.
Topics: Diclofenac; Double-Blind Method; Drug Combinations; Female; Gastrointestinal Diseases; Humans; Male; Misoprostol; Naproxen; Osteoarthritis; Piroxicam; Safety | 1993 |
Comparative studies with tolfenamic acid in rheumatic disorders.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Naproxen; ortho-Aminobenzoates; Osteoarthritis; Pain | 1994 |
A longterm endoscopic evaluation of patients with arthritis treated with nabumetone vs naproxen.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Double-Blind Method; Female; Follow-Up Studies; Gastroscopy; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Peptic Ulcer; Prospective Studies; Time Factors | 1994 |
A double blind study comparing the efficacy and safety of enteric coated naproxen to naproxen in the management of NSAID intolerant patients with rheumatoid arthritis and osteoarthritis. Naproxen EC Study Group.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Digestive System; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Safety; Tablets, Enteric-Coated | 1994 |
Comparison of piroxicam and naproxen in osteoarthritis of the foot.
Topics: Adult; Aged; Double-Blind Method; Foot Diseases; Humans; Middle Aged; Naproxen; Osteoarthritis; Piroxicam | 1994 |
[New methods of analysis of gait in the evaluation of the action of anti-inflammatory drugs. Apropos of naproxen].
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Female; Gait; Humans; Knee Joint; Male; Mathematical Computing; Middle Aged; Naproxen; Osteoarthritis; Osteoarthritis, Hip; Treatment Outcome | 1993 |
The comparative analgesic efficacy of transcutaneous electrical nerve stimulation and a non-steroidal anti-inflammatory drug for painful osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Pain Management; Pain Measurement; Transcutaneous Electric Nerve Stimulation; Treatment Outcome | 1994 |
[Fast-dissolving sublingual tablets of piroxicam versus naproxen in the treatment of recurrent acute osteoarthrosis. Multicenter clinical trial].
Topics: Acute Disease; Administration, Sublingual; Adult; Aged; Dosage Forms; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Piroxicam; Recurrence; Time Factors | 1994 |
Worldwide experience with etodolac (Lodine) 300 mg b.i.d. in the treatment of osteoarthritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Diclofenac; Double-Blind Method; Etodolac; Global Health; Hip Joint; Humans; Indomethacin; Knee Joint; Middle Aged; Naproxen; Osteoarthritis; Pain; Piroxicam; Time Factors | 1993 |
Comparison of naproxen and acetaminophen in a two-year study of treatment of osteoarthritis of the knee.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Arthrography; Double-Blind Method; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Patient Dropouts; Prospective Studies; Walking | 1993 |
Characterization of responders and nonresponders to tiaprofenic acid and naproxen in the treatment of patients with osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Discriminant Analysis; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Propionates; Treatment Outcome | 1993 |
Double-blind comparison of efficacy and gastroduodenal safety of diclofenac/misoprostol, piroxicam, and naproxen in the treatment of osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Diclofenac; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Misoprostol; Naproxen; Osteoarthritis; Peptic Ulcer; Piroxicam | 1993 |
Safety experience with nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Efficacy and safety of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in the elderly.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Male; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Efficacy of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Life Style; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
[Comparative analysis of three treatment regimens for treating gonarthritis with calcitonin, naproxen and flavonoids based on EULAR criteria and visual analogue scale (VAS)].
Topics: Calcitonin; Catechin; Cells, Cultured; Drug Therapy, Combination; Female; Flavonoids; Humans; Knee Joint; Male; Naproxen; Osteoarthritis; Pain Measurement | 1995 |
A comparison of Naprelan and Naprosyn in the treatment of osteoarthritis of the knee.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Double-Blind Method; Humans; Knee Joint; Middle Aged; Naproxen; Osteoarthritis; Treatment Outcome | 1996 |
Prevention with sucralfate gel of NSAID-induced gastroduodenal damage in arthritic patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Duodenal Ulcer; Female; Gels; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Stomach Ulcer; Sucralfate | 1996 |
Gastroduodenal tolerability of highly specific cyclo-oxygenase-2 inhibitor.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Gastric Mucosa; Humans; Indans; Isoenzymes; Knee Joint; Male; Membrane Proteins; Naproxen; Osteoarthritis; Osteoarthritis, Hip; Peroxidases; Prostaglandin-Endoperoxide Synthases | 1996 |
Etodolac (Lodine) in the treatment of osteoarthritis: recent studies.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Double-Blind Method; Etodolac; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Pain Measurement; Placebos | 1997 |
A randomized, double-blind, crossover comparative endoscopy study on the gastroduodenal tolerability of a highly specific cyclooxygenase-2 inhibitor, flosulide, and naproxen.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Duodenum; Endoscopy, Gastrointestinal; Female; Gastrointestinal Diseases; Humans; Indans; Intestinal Mucosa; Isoenzymes; Male; Membrane Proteins; Middle Aged; Naproxen; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Stomach | 1997 |
Double-blind, double-dummy endoscopic comparison of the mucosal protective effects of misoprostol versus ranitidine on naproxen-induced mucosal injury to the stomach and duodenum in rheumatic patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Double-Blind Method; Duodenal Ulcer; Duodenum; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Middle Aged; Misoprostol; Naproxen; Osteoarthritis; Placebos; Ranitidine; Stomach Ulcer | 1997 |
Aceclofenac is a well-tolerated alternative to naproxen in the treatment of osteoarthritis.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Diclofenac; Double-Blind Method; Drug Administration Schedule; Edema; Erythema; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Range of Motion, Articular; Treatment Outcome | 1997 |
Diclofenac/misoprostol: the European clinical experience.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Drug Combinations; Duodenal Ulcer; Duodenoscopy; Gastroscopy; Humans; Misoprostol; Naproxen; Osteoarthritis; Piroxicam; Stomach Ulcer | 1998 |
Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Aspirin; Celecoxib; Cyclooxygenase Inhibitors; Endoscopy; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazoles; Safety; Severity of Illness Index; Stomach Ulcer; Sulfonamides; Thromboxane B2; Treatment Outcome | 1998 |
NSAIDs and faecal blood loss in elderly patients with osteoarthritis: is plasma half-life relevant?
Topics: Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diclofenac; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Half-Life; Humans; Male; Middle Aged; Naproxen; Occult Blood; Osteoarthritis; Piroxicam | 1998 |
Intraarticular sodium hyaluronate (Hyalgan) in the treatment of patients with osteoarthritis of the knee: a randomized clinical trial. Hyalgan Study Group.
Topics: Adjuvants, Immunologic; Administration, Oral; Adult; Aged; Double-Blind Method; Female; Humans; Hyaluronic Acid; Injections, Intra-Articular; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Treatment Outcome | 1998 |
Tramadol allows reduction of naproxen dose among patients with naproxen-responsive osteoarthritis pain: a randomized, double-blind, placebo-controlled study.
Topics: Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Placebos; Single-Blind Method; Therapeutic Equivalency; Tramadol | 1999 |
Treatment of osteoarthritis with celecoxib, a cyclooxygenase-2 inhibitor: a randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Humans; Incidence; Isoenzymes; Membrane Proteins; Middle Aged; Naproxen; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Treatment Outcome | 1999 |
Study of the analgesic effect of lanepitant in patients with osteoarthritis pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Indoles; Male; Middle Aged; Naproxen; Neurokinin-1 Receptor Antagonists; Osteoarthritis; Pain; Pain Measurement; Piperidines | 2000 |
Upper gastrointestinal tolerability of celecoxib, a COX-2 specific inhibitor, compared to naproxen and placebo.
Topics: Abdominal Pain; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Digestive System; Double-Blind Method; Dyspepsia; Female; Humans; Isoenzymes; Male; Membrane Proteins; Middle Aged; Naproxen; Nausea; Osteoarthritis; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Risk Factors; Sulfonamides; Time Factors; Treatment Outcome | 2000 |
Functional status and health-related quality of life of elderly osteoarthritic patients treated with celecoxib.
Topics: Aged; Aged, 80 and over; Aging; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Health Status; Humans; Male; Naproxen; Osteoarthritis; Prospective Studies; Pyrazoles; Quality of Life; Sulfonamides | 2001 |
Pharmacokinetics, safety, and tolerability of BAY 12-9566 and nonsteroidal anti-inflammatory agents (naproxen, ibuprofen) during coadministration in patients with osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Area Under Curve; Biphenyl Compounds; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Metalloendopeptidases; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Phenylbutyrates | 2001 |
Double-blind study comparing the long-term efficacy of the COX-2 inhibitor nimesulide and naproxen in patients with osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Severity of Illness Index; Sulfonamides; Treatment Outcome | 2001 |
Chondroitin sulfate in erosive osteoarthritis of the hands.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Chondroitin Sulfates; Disease Progression; Drug Therapy, Combination; Female; Finger Joint; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Prospective Studies; Radiography; Time Factors | 2002 |
A randomized, double-blind, multicenter trial of nimesulide-beta-cyclodextrin versus naproxen in patients with osteoarthritis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Cyclodextrins; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Sulfonamides | 2002 |
Randomized placebo-controlled trial comparing efficacy and safety of valdecoxib with naproxen in patients with osteoarthritis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Digestive System; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Sulfonamides; Treatment Outcome | 2002 |
A comparison of benorylate and naproxen in degenerative arthritis.
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Salicylates | 1978 |
Experience with naproxen in treating osteoarthritis.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Placebos | 1977 |
Diclofenac (Voltaren) for the treatment of osteo-arthrosis: a double-blind comparison with naproxen.
Topics: Aged; Clinical Trials as Topic; Diclofenac; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Phenylacetates | 1977 |
[Proquazone in the treatment of osteoarthritis of the knee: a double-blind comparison with naproxen (author's transl)].
Topics: Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Joint Diseases; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Quinazolines | 1977 |
Naproxen in osteoarthrosis. Double-blind crossover trial.
Topics: Activities of Daily Living; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Hip Joint; Humans; Knee Joint; Male; Naproxen; Osteoarthritis | 1978 |
A long-term comparison of proquazone and naproxen in the treatment of osteoarthritis of the hip.
Topics: Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Drug Evaluation; Female; Hip Joint; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Quinazolines; Time Factors | 1978 |
A double-blind multicentre comparison of diclofenac sodium and naproxen in osteoarthrosis of the hip.
Topics: Adult; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Female; Hip Joint; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Phenylacetates | 1978 |
Naproxen vs. aspirin in osteoarthritis of the hip and knee.
Topics: Adult; Aged; Aspirin; Central Nervous System Diseases; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Naproxen; Osteoarthritis | 1978 |
Successful use of a moderate analgesic (Fortagesic) in the symptomatic treatment of osteoarthritis.
Topics: Acetaminophen; Drug Combinations; Female; Humans; Male; Naproxen; Osteoarthritis; Pentazocine | 1979 |
Double-blind study of Naproxen in osteoarthritis of the knee joint.
Topics: Activities of Daily Living; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Evaluation; Female; Gastrointestinal Hemorrhage; Humans; Knee Joint; Male; Middle Aged; Movement; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Placebos; Radiography; Skin Temperature; Stomach Ulcer | 1976 |
Clinical and objective assessments of naproxen through 5 years of clinical experience.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Chronic Disease; Clinical Trials as Topic; Female; Follow-Up Studies; Gout; Humans; Indomethacin; Long-Term Care; Male; Middle Aged; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Placebos; Polymyalgia Rheumatica | 1975 |
A double-blind comparison of naproxen with indomethacin in osteoarthrosis.
Topics: Anti-Inflammatory Agents; Clinical Trials as Topic; Humans; Indomethacin; Naphthaleneacetic Acids; Naproxen; Osteoarthritis | 1975 |
[Treatment of osteoarthrosis with naproxen].
Topics: Aged; Clinical Trials as Topic; Drug Evaluation; Female; Hip Joint; Humans; Knee Joint; Male; Middle Aged; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Placebos | 1975 |
A Double-blind comparison of naproxen against indometacin in osteoarthrosis.
Topics: Clinical Trials as Topic; Hip Joint; Humans; Indomethacin; Knee Joint; Naphthaleneacetic Acids; Naproxen; Osteoarthritis | 1975 |
[Methods and statistics of multicentral double-blind "cross-over" examination of naproxen compared to indomethacin].
Topics: Aged; Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Indomethacin; Male; Medical Records; Methods; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Pain; Spondylitis, Ankylosing; Statistics as Topic | 1975 |
[Clinical results of a multicentral double-blind examination of naproxen compared to indomethacin in chronic rheumatoid arthritis, ankylosing spondylitis, and osteoarthrosis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Indomethacin; Male; Middle Aged; Naphthaleneacetic Acids; Naproxen; Nausea; Osteoarthritis; Spondylitis, Ankylosing; Tinnitus; Vertigo | 1975 |
[Observations of long-term treatment of arthrosis with naproxen].
Topics: Adult; Aged; Blood Sedimentation; Clinical Trials as Topic; Depression, Chemical; Female; Follow-Up Studies; Hip Joint; Humans; Joint Diseases; Knee Joint; Leukocyte Count; Male; Middle Aged; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Phenylbutazone; Prednisone | 1975 |
Enteric coated naproxen; a double blind trial comparing the tolerance of enteric coated and standard formulations.
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Tablets, Enteric-Coated | 1992 |
Enteric-coated and plain naproxen tablets in osteoarthritis; tolerability and efficacy.
Topics: Adult; Aged; Cross-Over Studies; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Tablets; Tablets, Enteric-Coated | 1992 |
Clinical efficacy and safety of nabumetone in rheumatoid arthritis and osteoarthritis.
Topics: Adult; Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Butanones; Double-Blind Method; Female; Humans; Longitudinal Studies; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis | 1992 |
Efficacy and tolerability of enteric-coated naproxen in the treatment of osteoarthritis and rheumatoid arthritis: a double-blind comparison with standard naproxen followed by an open-label trial.
Topics: Adult; Aged; Arthritis, Rheumatoid; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Tablets, Enteric-Coated | 1992 |
Open-label tolerability study of enteric-coated naproxen in the treatment of osteoarthritis and rheumatoid arthritis.
Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Tablets, Enteric-Coated | 1992 |
The efficacy and tolerability of enteric and non-enteric coated naproxen tablets: a double-blind study in patients with osteoarthritis.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Patient Satisfaction; Range of Motion, Articular; Severity of Illness Index; Tablets, Enteric-Coated | 1991 |
Analgesic activity of nabumetone versus naproxen in acute exacerbation of osteoarthritis. A short term study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Drug Evaluation; Female; Humans; Male; Nabumetone; Naproxen; Osteoarthritis | 1990 |
Endoscopic evaluation of etodolac and naproxen, and their relative effects on gastric and duodenal prostaglandins.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Dinoprostone; Dose-Response Relationship, Drug; Duodenum; Endoscopy; Epoprostenol; Etodolac; Female; Gastric Mucosa; Humans; Indoleacetic Acids; Male; Middle Aged; Mucous Membrane; Naproxen; Osteoarthritis; Patient Compliance; Prostaglandins; Stomach; Thromboxane B2; Time Factors | 1990 |
[Clinical use of naproxen sodium in muscular skeletal disorders].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Naproxen; Osteoarthritis | 1990 |
Quantitative analysis of walking in patients with knee osteoarthritis: a method of assessing the effectiveness of non-steroidal anti-inflammatory treatment.
Topics: Aged; Disability Evaluation; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Walking | 1990 |
Recent clinical experience with etodolac in the treatment of osteoarthritis of the knee.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Etodolac; Female; Humans; Indoleacetic Acids; Knee Joint; Male; Middle Aged; Multicenter Studies as Topic; Naproxen; Osteoarthritis; Piroxicam; Random Allocation | 1989 |
A global safety evaluation of etodolac.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Etodolac; Female; Humans; Indoleacetic Acids; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam | 1989 |
Pharmacokinetic properties and clinical efficacy of once-daily sustained-release naproxen.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Random Allocation | 1989 |
A double-blind trial of ademetionine vs naproxen in activated gonarthrosis.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Random Allocation; S-Adenosylmethionine | 1989 |
Epidemiology of NSAID-related gastrointestinal side effects.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Gastric Mucosa; Gastrointestinal Diseases; Humans; Male; Middle Aged; Multicenter Studies as Topic; Naproxen; Osteoarthritis; Piroxicam | 1989 |
Effect of naproxen on renal haemodynamics in elderly patients with arthritis.
Topics: Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Glomerular Filtration Rate; Humans; Male; Naproxen; Osteoarthritis; Random Allocation; Renal Circulation | 1989 |
Clinical evaluation of a new controlled-release formulation of naproxen in osteoarthritis and rheumatoid arthritis. Canadian Multicentre Study Group.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Random Allocation | 1988 |
Piroxicam and naproxen in patients with osteoarthritis of the hip waiting for total hip replacement.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Clinical Trials as Topic; Double-Blind Method; Female; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Piroxicam; Random Allocation | 1988 |
Controlled-release naproxen compared with isoxicam in patients with osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam; Random Allocation | 1988 |
A 6-month, double-blind study comparing nabumetone to naproxen in the treatment of osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Weight; Butanones; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Random Allocation | 1987 |
Endoscopy-controlled study of the safety of nabumetone compared with naproxen in arthritis therapy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; Double-Blind Method; Duodenoscopy; Endoscopy; Esophagoscopy; Female; Gastric Mucosa; Gastroscopy; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis | 1987 |
Nabumetone versus naproxen in the treatment of osteoarthritis. A six-month trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Random Allocation | 1987 |
Six-month multi-center study comparing nabumetone with naproxen in the treatment of osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Random Allocation | 1987 |
Italian double-blind multicenter study comparing S-adenosylmethionine, naproxen, and placebo in the treatment of degenerative joint disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Placebos; Random Allocation; S-Adenosylmethionine | 1987 |
A multicenter study of the safety and efficacy of naproxen: analysis of blood pressure.
Topics: Adult; Aged; Blood Pressure; Humans; Hypertension; Middle Aged; Multicenter Studies as Topic; Naproxen; Osteoarthritis; Safety | 1988 |
A double-blind multicentre trial of piroxicam and naproxen in osteoarthritis.
Topics: Aged; Cardiovascular Diseases; Central Nervous System Diseases; Clinical Trials as Topic; Double-Blind Method; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Piroxicam; Thiazines | 1986 |
International experiences with diclofenac in osteoarthritis.
Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Naproxen; Osteoarthritis; Random Allocation; Sulindac | 1986 |
Efficacy of diclofenac in osteoarthritis. Experience in the United States.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Hip Joint; Humans; Knee Joint; Middle Aged; Naproxen; Osteoarthritis; Random Allocation; United States | 1986 |
Naproxen and piroxicam in the treatment of osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam; Random Allocation; Thiazines | 1986 |
A single blind randomized endoscopic study comparing the effects of diflunisal and naproxen in patients with osteoarthritis.
Topics: Adult; Aged; Clinical Trials as Topic; Diflunisal; Digestive System; Drug Tolerance; Endoscopy; Gastric Mucosa; Humans; Intestinal Mucosa; Middle Aged; Naproxen; Osteoarthritis; Random Allocation; Salicylates | 1986 |
Piroxicam and naproxen plasma concentrations in patients with osteoarthritis: relation to age, sex, efficacy and adverse events.
Topics: Age Factors; Aged; Aged, 80 and over; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Kinetics; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam; Prospective Studies; Random Allocation; Sex Factors | 1986 |
The Norway study: plasma concentrations, efficacy, and adverse events.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Body Weight; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhage; Heart Failure; Humans; Male; Middle Aged; Naproxen; Norway; Osteoarthritis; Peptic Ulcer; Piroxicam; Sex Factors | 1986 |
Clinical benefits and comparative safety of piroxicam. Analysis of worldwide clinical trials data.
Topics: Adult; Age Factors; Aged; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Information Systems; Male; Middle Aged; Naproxen; Norway; Osteoarthritis; Peptic Ulcer; Piroxicam; Product Surveillance, Postmarketing; United Kingdom | 1986 |
The Norwegian multicenter study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Naproxen; Norway; Osteoarthritis; Peptic Ulcer; Piroxicam; Random Allocation; Sex Factors | 1986 |
[Piroxicam and naproxen in arthrosis. A double-blind, comparative multicenter study in general practice].
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Family Practice; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam | 1986 |
[Diacereine: an original approach in the treatment of degenerative and/or extra-articular rheumatism].
Topics: Administration, Oral; Adult; Aged; Anthraquinones; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis | 1987 |
Efficacy of diflunisal versus naproxen in osteoarthritis of the knee: an open study.
Topics: Adult; Aged; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Salicylates | 1986 |
Efficacy and tolerance of naproxen versus pirprofen in the treatment of patients with osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Phenylpropionates; Random Allocation | 1987 |
Double-blind multicentre UK hospital studies of isoxicam vs naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Piroxicam; Random Allocation | 1986 |
A double-blind crossover trial of diflunisal and naproxen in osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Diflunisal; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Random Allocation; Salicylates | 1987 |
An open study of 1.5 g naproxen daily in osteoarthritis.
Topics: Aged; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Time Factors | 1985 |
[Clinical trials with pirprofen and naproxen in patients with gonarthrosis and coxarthrosis].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blind Method; Female; Hip Joint; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Phenylpropionates | 1985 |
A comparison of naproxen and diclofenac sodium in the treatment of osteoarthritis in elderly patients.
Topics: Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Humans; Male; Naproxen; Osteoarthritis; Phenylacetates | 1985 |
Comparison of a slow-release indomethacin tablet and naproxen in osteoarthrosis.
Topics: Adult; Aged; Central Nervous System Diseases; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Gastrointestinal Diseases; Hip Joint; Humans; Indomethacin; Knee Joint; Male; Middle Aged; Movement; Naproxen; Osteoarthritis; Pain; Random Allocation; Tablets | 1985 |
A double-blind crossover evaluation of naproxen and piroxicam in osteoarthritis of hip or knee.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Hip Joint; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam; Thiazines | 1985 |
Double-blind preference and compliance multicentre study in osteoarthritis: once-a-day treatment.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Administration Schedule; Humans; Indomethacin; Indoprofen; Ketoprofen; Middle Aged; Naproxen; Osteoarthritis; Pain; Patient Compliance; Piroxicam; Thiazines | 1985 |
Double-blind crossover comparison of piroxicam and naproxen in the treatment of active osteoarthritis.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam; Thiazines | 1985 |
72 other study(ies) available for naproxen and Arthritis, Degenerative
| Article | Year |
|---|---|
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Carrageenan; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hyperalgesia; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Membrane Proteins; Molecular Structure; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides | 1997 |
Interactions of Nonsteroidal Antiinflammatory Drugs and Aspirin and Risk of Cardiovascular Disease in Patients With Osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Humans; Ibuprofen; Naproxen; Osteoarthritis | 2023 |
Association of tramadol with risk of myocardial infarction among patients with osteoarthritis.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Diclofenac; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Naproxen; Osteoarthritis; Propensity Score; Proportional Hazards Models; Risk Factors; Tramadol | 2020 |
Injectable hydrogel-based drug delivery system for cartilage regeneration.
Topics: Animals; Cartilage; Drug Delivery Systems; Humans; Hydrogels; Naproxen; Osteoarthritis; Tissue Engineering | 2020 |
Naproxen treatment inhibits articular cartilage loss in a rat model of osteoarthritis.
Topics: Acetaminophen; Animals; Cartilage, Articular; Disease Models, Animal; Female; Naproxen; Osteoarthritis; Rats; Rats, Sprague-Dawley | 2021 |
Evaluation of cardiovascular risk associated with SKI306X use in patients with osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Cohort Studies; Drugs, Chinese Herbal; Female; Humans; Incidence; Male; Middle Aged; Naproxen; Osteoarthritis; Retrospective Studies; Risk Factors; Time Factors; Young Adult | 2017 |
NSAIDs relieve osteoarthritis (OA) pain, but cardiovascular safety in question even for diclofenac, ibuprofen, naproxen, and celecoxib: what are the alternatives?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Diclofenac; Humans; Ibuprofen; Naproxen; Network Meta-Analysis; Osteoarthritis; Pain | 2017 |
Risk of myocardial infarction with use of selected non-steroidal anti-inflammatory drugs in patients with spondyloarthritis and osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Diclofenac; Female; Humans; Male; Middle Aged; Myocardial Infarction; Naproxen; Osteoarthritis; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Spondylarthritis; Young Adult | 2018 |
Naproxen induces type X collagen expression in human bone-marrow-derived mesenchymal stem cells through the upregulation of 5-lipoxygenase.
Topics: Aged; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bone Marrow Cells; Collagen Type X; Core Binding Factor Alpha 1 Subunit; Enzyme Activation; Female; Humans; Male; Mesenchymal Stem Cells; Middle Aged; Mitogen-Activated Protein Kinases; Models, Biological; Naproxen; Osteoarthritis; Phosphorylation; Protein Kinase Inhibitors; Up-Regulation | 2015 |
Nonsteroidal anti-inflammatory drugs in-vitro and in-vivo treatment and Multidrug Resistance Protein 4 expression in human platelets.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Case-Control Studies; Celecoxib; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Megakaryocytes; Middle Aged; Multidrug Resistance-Associated Proteins; Naproxen; Osteoarthritis; Platelet Activation; Platelet Aggregation; RNA, Messenger | 2016 |
Therapy: Cardiovascular safety of celecoxib, naproxen and ibuprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular System; Celecoxib; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; Naproxen; Osteoarthritis; Outcome Assessment, Health Care; Safety | 2017 |
Cyclooxygenase-inhibiting nitric oxide donators for osteoarthritis.
Topics: Animals; Blood Pressure; Cardiovascular System; Cyclooxygenase Inhibitors; Gastrointestinal Diseases; Humans; Naproxen; Nitric Oxide Donors; Osteoarthritis | 2009 |
Periorbital edema associated with separate courses of ibuprofen and naproxen.
Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Edema; Eye Diseases; Female; Humans; Ibuprofen; Naproxen; Osteoarthritis | 2010 |
Cost analysis of flavocoxid compared to naproxen for management of mild to moderate OA.
Topics: Aged; Aged, 80 and over; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Comorbidity; Costs and Cost Analysis; Drug Combinations; Hospitalization; Humans; Models, Economic; Naproxen; Osteoarthritis; Severity of Illness Index | 2010 |
Naproxcinod.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Naproxen; Nitric Oxide Donors; Osteoarthritis | 2012 |
Summaries for patients. Gastrointestinal side effects of rofecoxib and naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Hypertension; Lactones; Male; Middle Aged; Naproxen; Osteoarthritis; Prospective Studies; Sulfones | 2003 |
Longer use of COX-2-specific inhibitors compared to nonspecific nonsteroidal antiinflammatory drugs: a longitudinal study of 3639 patients in community practice.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Community Health Services; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Fibromyalgia; Follow-Up Studies; Humans; Ibuprofen; Isoenzymes; Lactones; Longitudinal Studies; Male; Membrane Proteins; Middle Aged; Naproxen; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones; Surveys and Questionnaires | 2004 |
Tolerability of rofecoxib versus naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Drug Industry; Gastrointestinal Diseases; Humans; Lactones; Naproxen; Osteoarthritis; Research; Sulfones | 2004 |
Tolerability of rofecoxib versus naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Data Interpretation, Statistical; Gastrointestinal Diseases; Humans; Lactones; Naproxen; Osteoarthritis; Sulfones | 2004 |
Tolerability of rofecoxib versus naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Data Interpretation, Statistical; Gastrointestinal Diseases; Humans; Lactones; Naproxen; Osteoarthritis; Sulfones | 2004 |
[Selective cox-2 inhibitors. Better tolerance than NSAID plus antacid].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endoscopy, Digestive System; Gastric Mucosa; Humans; Intestinal Mucosa; Isoenzymes; Membrane Proteins; Middle Aged; Naproxen; Omeprazole; Osteoarthritis; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases; Proton Pump Inhibitors; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides | 2004 |
Evidence in practice--number 3: Cox 2 inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Evidence-Based Medicine; Humans; Ibuprofen; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Stomach Ulcer | 2004 |
Report of specific cardiovascular outcomes of the ADVANTAGE trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Gastrointestinal Diseases; Humans; Lactones; Naproxen; Osteoarthritis; Sulfones | 2005 |
Modulation of insulin-like growth factor 1 levels in human osteoarthritic subchondral bone osteoblasts.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Culture Media; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Female; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Protein 5; Insulin-Like Growth Factor I; Isoquinolines; Male; Middle Aged; Naproxen; Osteoarthritis; Osteoblasts; Parathyroid Hormone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides | 2006 |
[By what means does the rheumatic patient with gastrointestinal risks fare best?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Controlled Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Etoricoxib; Gastrointestinal Diseases; Germany; Humans; Naproxen; Osteoarthritis; Proton Pump Inhibitors; Pyridines; Rheumatic Diseases; Risk Factors; Sulfones; United States | 2007 |
An economic model of long-term use of celecoxib in patients with osteoarthritis.
Topics: Age Factors; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cost-Benefit Analysis; Diclofenac; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Long-Term Care; Male; Maximum Tolerated Dose; Middle Aged; Models, Economic; Naproxen; Osteoarthritis; Probability; Pyrazoles; Quality-Adjusted Life Years; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Sulfonamides | 2007 |
Naproxen, meloxicam and methylprednisolone inhibit urokinase plasminogen activator and inhibitor and gelatinases expression during the early stage of osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gelatinases; Humans; Meloxicam; Methylprednisolone; Naproxen; Osteoarthritis; Thiazines; Thiazoles; Urokinase-Type Plasminogen Activator | 2008 |
[Developmental toxicity of naproxen].
Topics: Abnormalities, Drug-Induced; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ductus Arteriosus; Dysmenorrhea; Female; Heart Septal Defects, Ventricular; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Mice; Naproxen; Osteoarthritis; Persistent Fetal Circulation Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Rats; Species Specificity | 2007 |
Risk of ischaemic cardiovascular events from selective cyclooxygenase-2 inhibitors in osteoarthritis.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cohort Studies; Cyclooxygenase 2 Inhibitors; Databases, Factual; Female; Follow-Up Studies; Humans; Isoxazoles; Lactones; Male; Middle Aged; Myocardial Infarction; Naproxen; Osteoarthritis; Proportional Hazards Models; Pyrazoles; Retrospective Studies; Risk Factors; Stroke; Sulfonamides; Sulfones; United States | 2008 |
Double-blind study of suprofen vs naproxen in the treatment of osteoarthritic pain.
Topics: Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Palliative Care; Phenylpropionates; Suprofen | 1983 |
[Double-blind study of tolmetin osteoarthritis (author's transl)].
Topics: Adult; Aged; Back Pain; Double-Blind Method; Humans; Middle Aged; Naproxen; Osteoarthritis; Pyrroles; Spinal Diseases; Tolmetin | 1980 |
Phototoxic reactions to piroxicam, naproxen and tiaprofenic acid.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Humans; Male; Naproxen; Osteoarthritis; Photosensitivity Disorders; Piroxicam; Propionates; Thiazines | 1983 |
[Efficacy and tolerance of Proxen 500 mg film-coated tablets in coxarthrosis].
Topics: Adult; Aged; Dosage Forms; Drug Tolerance; Female; Hip Joint; Humans; Male; Middle Aged; Naproxen; Osteoarthritis | 1983 |
[Effect of naprosin on the clinical picture and selected biochemical parameters in degenerative diseases of the peripheral joints].
Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Anti-Inflammatory Agents; Female; Humans; Joints; Male; Middle Aged; Naproxen; Osteoarthritis | 1983 |
Renal papillary necrosis following regular consumption of non-steroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Papillary Necrosis; Male; Middle Aged; Naproxen; Osteoarthritis | 1982 |
Osteoarthritis and non-steroidal and anti-inflammatory drugs: a multi-centre comparative study.
Topics: Aged; Diclofenac; Female; Hip Joint; Humans; Ibuprofen; Indenes; Knee Joint; Male; Naproxen; Osteoarthritis; Sulindac | 1982 |
[Naprosyn in the treatment of osteoarthrosis].
Topics: Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis | 1980 |
Effects of nimesulide and naproxen on the degradation and metalloprotease synthesis of human osteoarthritic cartilage.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cartilage; Collagenases; Humans; In Vitro Techniques; Matrix Metalloproteinase 3; Metalloendopeptidases; Naproxen; Osteoarthritis; Proteoglycans; Sulfonamides | 1993 |
Histological findings in gastric mucosa in patients treated with non-steroidal anti-inflammatory drugs.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Female; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Ketoprofen; Male; Middle Aged; Naproxen; Osteoarthritis | 1995 |
Regulation of human normal and osteoarthritic chondrocyte interleukin-1 receptor by antirheumatic drugs.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Dexamethasone; Humans; Hydrocortisone; Indoles; Indomethacin; Metalloendopeptidases; Naproxen; Osteoarthritis; Oxindoles; Prostaglandins E; Protein Binding; Receptors, Interleukin-1 | 1993 |
The in vivo effects of naproxen on canine experimental osteoarthritic articular cartilage: composition, metalloproteinase activities and metabolism.
Topics: Animals; Cartilage, Articular; Dogs; Female; Joints; Metalloendopeptidases; Naproxen; Osteoarthritis; Proteoglycans | 1993 |
A remembrance of Fred, the lowland gorilla.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ape Diseases; Gorilla gorilla; Male; Naproxen; Osteoarthritis; Osteoarthritis, Hip; Shoulder Joint; Treatment Outcome | 1996 |
Diacerhein and rhein reduce the interleukin 1beta stimulated inducible nitric oxide synthesis level and activity while stimulating cyclooxygenase-2 synthesis in human osteoarthritic chondrocytes.
Topics: Aged; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Humans; Interleukin-1; Isoenzymes; Male; Membrane Proteins; Middle Aged; Naproxen; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Osteoarthritis; Prostaglandin-Endoperoxide Synthases | 1998 |
Naproxen-induced lichen planus bullosus.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Lichen Planus; Middle Aged; Naproxen; Osteoarthritis; Skin Diseases, Vesiculobullous | 1999 |
Preference for nonsteroidal antiinflammatory drugs versus acetaminophen and concomitant use of both types of drugs in patients with osteoarthritis.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Data Collection; Diclofenac; Female; Humans; Ibuprofen; Male; Naproxen; Osteoarthritis; Patient Satisfaction; Self Administration; Surveys and Questionnaires | 2000 |
Differential regulation of interleukin-1 beta-induced cyclooxygenase-2 gene expression by nimesulide in human synovial fibroblasts.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Interleukin-1; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Naproxen; Nitrobenzenes; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides; Synovial Membrane | 2001 |
Endogenous prostaglandin E2 and insulin-like growth factor 1 can modulate the levels of parathyroid hormone receptor in human osteoarthritic osteoblasts.
Topics: Aged; Aged, 80 and over; Bone Remodeling; Cells, Cultured; Cholera Toxin; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Female; Gene Expression Regulation; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Naproxen; Osteoarthritis; Osteoblasts; Parathyroid Hormone; Pertussis Toxin; Receptor, IGF Type 1; Receptors, Parathyroid Hormone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Second Messenger Systems; Virulence Factors, Bordetella | 2001 |
Celecoxib in osteoarthritis and rheumatoid arthritis: new preparation. As disappointing as rofecoxib.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; France; Humans; Naproxen; Osteoarthritis; Sulfonamides; Treatment Outcome | 2001 |
Adverse cutaneous reaction to naproxen: a missed diagnosis fortuitously resolved.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Body Water; Diagnostic Errors; Exanthema; Humans; Male; Naproxen; Osteoarthritis; Salts | 2002 |
Trends in medication use for osteoarthritis treatment.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Drug Utilization; Female; Humans; Ibuprofen; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; United States | 2002 |
Right ballpark, wrong base: assessing safety of NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Isoxazoles; Lactones; Naproxen; Osteoarthritis; Peptic Ulcer; Sulfonamides; Sulfones | 2002 |
New antirheumatic agents: Fenoprofen calcium (Nalfon), naproxen (Naprosyn), and tolmetin sodium (Tolectin).
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Gastrointestinal Hemorrhage; Humans; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Phenylpropionates; Pyrroles; Rheumatic Diseases; Spondylitis, Ankylosing; Tolmetin | 1977 |
[Naprosyn, a new nonsteroid antirheumatic agent with a long biological half-life].
Topics: Arthritis, Rheumatoid; Female; Half-Life; Humans; Kinetics; Male; Middle Aged; Naproxen; Osteoarthritis; Spondylitis, Ankylosing | 1978 |
[Experiences with the effect of naproxen in chronic and degenerative diseases as in overload conditions of the postural and locomotor system].
Topics: Adult; Aged; Arthritis, Rheumatoid; Capsules; Chronic Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Periarthritis; Suppositories; Tendinopathy | 1975 |
[Methoxypropriocin in the treatment of degenerative bone disease (comparative studies)].
Topics: Aspirin; Benzydamine; Chronic Disease; Humans; Indomethacin; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Spondylitis, Ankylosing | 1976 |
Reversible bone marrow aplasia induced by naproxen.
Topics: Aged; Anemia, Aplastic; Female; Humans; Naproxen; Osteoarthritis; Red-Cell Aplasia, Pure | 1992 |
Naproxen free plasma concentrations and unbound fractions in patients with osteoarthritis: relation to age, sex, efficacy, and adverse events.
Topics: Aged; Aged, 80 and over; Aging; Blood Proteins; Creatinine; Female; Humans; Male; Naproxen; Osteoarthritis; Serum Albumin; Sex Factors; Urea | 1991 |
Improved cost-effectiveness ratio with a patient self-adjusted naproxen dosing regimen in osteoarthritis treatment.
Topics: Aged; Cost-Benefit Analysis; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; Male; Naproxen; Osteoarthritis; Self Administration | 1991 |
Acute eosinophilic colitis and hypersensitivity reaction associated with naproxen therapy.
Topics: Acute Disease; Colitis; Drug Hypersensitivity; Eosinophilia; Female; Follow-Up Studies; Humans; Middle Aged; Naproxen; Osteoarthritis | 1990 |
Ketoprofen vs naproxen or diclofenac sodium in osteoarthritis.
Topics: Diclofenac; Humans; Ketoprofen; Multicenter Studies as Topic; Naproxen; Osteoarthritis | 1990 |
Generalised eruptive pustular drug rash due to naproxen.
Topics: Drug Eruptions; Humans; Naproxen; Osteoarthritis | 1989 |
[Efficacy of sucralfate in the prevention of stomach diseases induced by non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam; Stomach Diseases; Sucralfate; Time Factors | 1989 |
Symptomatic treatment of osteoarthrosis with two different oral preparations of naproxen.
Topics: Administration, Oral; Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis | 1989 |
Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Duodenal Ulcer; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Peptic Ulcer Hemorrhage; Piroxicam; Smoking; Stomach Ulcer; Surveys and Questionnaires; Thiazines | 1986 |
Naproxen kinetics in synovial fluid of patients with osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Half-Life; Humans; Middle Aged; Naproxen; Osteoarthritis; Synovial Fluid | 1988 |
Naproxen tolerability in the elderly: a summary report.
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Humans; Naproxen; Osteoarthritis; Patient Dropouts; Retrospective Studies | 1987 |
Pharmacokinetics of naproxen in elderly patients.
Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Proteins; Female; Half-Life; Humans; Kinetics; Male; Middle Aged; Naproxen; Osteoarthritis; Urea | 1986 |
Transmural pyloric perforation associated with naproxen administration in a dog.
Topics: Animals; Dog Diseases; Dogs; Male; Naproxen; Osteoarthritis; Pylorus | 1986 |
[Pirprofen in the treatment of exacerbated osteoarthrosis in the aged. Controlled research in comparison with naproxen].
Topics: Aged; Double-Blind Method; Female; Humans; Male; Naproxen; Osteoarthritis; Pain; Phenylpropionates | 1986 |
Acute reversible renal failure following naproxen (naxyn) administration.
Topics: Acute Kidney Injury; Female; Humans; Middle Aged; Naproxen; Osteoarthritis | 1986 |
Worldwide experience with diclofenac in rheumatoid arthritis and osteoarthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Diclofenac; Double-Blind Method; Humans; Indomethacin; Naproxen; Osteoarthritis; Sulindac; Tolmetin | 1985 |
Diclofenac sodium in the treatment of rheumatoid arthritis and osteoarthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Pain | 1985 |