Compounds > naproxen
Page last updated: 2024-09-04

naproxen and Anasarca

naproxen has been researched along with Anasarca in 88 studies

Research

Studies (88)

TimeframeStudies, this research(%)All Research%
pre-199023 (26.14)18.7374
1990's14 (15.91)18.2507
2000's25 (28.41)29.6817
2010's24 (27.27)24.3611
2020's2 (2.27)2.80

Authors

AuthorsStudies
Heikes, JE; Sprague, PW1
Ackrell, J; Antonio, Y; Franco, F; Landeros, R; Leon, A; Maddox, ML; Muchowski, JM; Nelson, PH; Rooks, WH; Roszkowski, AP; Wallach, MB1
Asselin, AA; Dobson, TA; Humber, LG; Komlossy, J1
Carty, TJ; Moore, PF; Mylari, BL; Zembrowski, WJ1
Ackerman, N; Ballaron, SA; Galeazzi, E; Greenhouse, R; Guzmán, A; Muchowski, JM; Peréz, V; Rovito, JR; Tomolonis, AJ; Young, JM1
Millonig, RC; Rovnyak, GC; Schwartz, J; Shu, V1
Boettcher, I; Elger, W; Kirsch, G; Siegmund, F; Wachtel, H1
Casler, JJ; Collins, PW; Gregory, SA; Isakson, PC; Khanna, IK; Koboldt, CM; Koszyk, FJ; Masferrer, JL; Perkins, WE; Seibert, K; Veenhuizen, AW; Weier, RM; Xu, XD; Yu, Y; Zhang, YY1
Darolia, R; Dobson, RL; Eichhold, TH; Enzweiler, K; Farmer, RW; Gan, L; Green, SA; Hennes, D; Janusz, JM; Kellstein, DE; Kuhlenbeck, DL; Magrisso, IJ; Matthews, RS; Ridgeway, JM; Rosario-Jansen, T; Scherz, MW; Sirko, SP; Tulich, JL; Wehmeyer, KR; Wu, LI; Young, PA1
Dobson, RL; Eichhold, TH; Enzweiler, K; Gan, L; Green, SA; Janusz, JM; Johnson, CR; Kellstein, DE; Kuhlenbeck, DL; Magrisso, IJ; McDow-Dunham, KL; Pikul, S; Rosario-Jansen, T; Scherz, MW; Senanayake, CB; Tulich, JL; Wehmeyer, KR; Wu, LI; Young, PA1
Chen, J; Dobson, RL; Eichhold, TH; Enzweiler, K; Gan, L; Green, SA; Janusz, JM; Kellstein, DE; Kuhlenbeck, DL; Magrisso, IJ; Ridgeway, JM; Rosario-Jansen, T; Scherz, MW; Tulich, JL; Wehmeyer, KR; Wu, LI; Young, PA1
Cogburn, JN; Collins, PW; Huff, RM; Isakson, PC; Khanna, IK; Koboldt, CM; Koszyk, FJ; Masferrer, JL; Perkins, WE; Seibert, K; Veenhuizen, AW; Weier, RM; Xu, X; Yang, DC; Yu, Y; Yuan, J; Zhang, YY1
Bedard, PW; Camphausen, RT; DeBernardo, S; Janz, K; Kaila, N; Keith, JC; Nickerson-Nutter, C; Shilling, A; Tam, S; Tsao, DH; Wang, Q; Young-Sciame, R1
Adams, JK; Bradshaw, HB; Burstein, SH; Fraioli, C; Rossetti, RG; Salmonsen, RA; Shaw, JW; Walker, JM; Zipkin, RE; Zurier, RB1
Abraham, WM; Albert, L; Behnke, ML; Chen, L; Clark, JD; Donahue, F; Foley, MA; Goodwin, DG; Hegen, M; Hu, B; Hu, Y; Ipek, M; Keith, J; Kirincich, SJ; Ku, MS; Lee, KL; McKew, JC; Michalak, R; Murphy, EA; Nickerson-Nutter, CL; Ramarao, MK; Shen, MW; Sum, FW; Tam, S; Thakker, P; Thomason, J; Williams, C; Wooder, L; Wu, K; Xu, X1
Girish, V; Khanum, NF; Khanum, SA; Suparshwa, SS1
Abdellatif, KR; Chowdhury, MA; DuMond, JF; Huang, Z; King, SB; Knaus, EE; Reisz, JA; Velázquez, CA1
Chaudhaery, SS; Eleftheriou, P; Filimonov, D; Filz, O; Geronikaki, A; Hadjipavlou-Litina, D; Poroikov, V; Roy, KK; Saxena, AK; Vicini, P1
Afzal, O; Bawa, S; Chawla, G; Deora, GS; Kalle, AM; Kumar, S; Mulakayala, N; Rajaram, A; Rathore, V; Tonk, RK1
Apostolidis, I; Ćirić, A; Gavalas, A; Geronikaki, A; Glamočlija, J; Hadjipavlou-Litina, D; Liaras, K; Soković, M1
Kourounakis, AP; Matralis, AN1
Alonso-Castro, AJ; Campos-Xolalpa, N; Hernández-Munive, A; Pérez-González, C; Pérez-Gutiérrez, S; Zapata-Morales, JR1
Ertan, M; Kazkayasi, I; Okay, G; Ozadali-Sari, K; Sarigol, D; Somuncuoglu, EI; Tel, BC; Tozkoparan, B; Unsal-Tan, O; Uzgoren-Baran, A1
Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P1
Gavalas, A; Kourti, M; Rekka, EA; Theodosis-Nobelos, P1
Boixareu, N; Campanera, JM; Navarro, L; Pors, K; Pouplana, R; Pujol, MD; Rosell, G; Sánchez, S1
Avci, A; Can, ÖD; Gökhan-Kelekçi, N; Kandemir, Ü; Taşci, H; Tozkoparan, B1
Eleftheriou, P; Gavalas, A; Geronikaki, A; Haroun, M; Kamoutsis, C; Kochkar, H; Nair, AB; Paparisva, A; Petrou, A; Tratrat, C; Venugopala, KN1
Jarosz, M; Librowski, T; Marona, H; Młyniec, K; Nowak, G; Szkaradek, N1
Cigerim, L; Eroglu, CN1
Acar, AH; Bayer, S; Demirtas, N; Kazancioglu, HO; Mihmanli, A; Yilmaz, N1
Ertan, G; Heard, CM; Yurdasiper, A1
Abdel-Rahman, RF; Al-Harbi, LM; El-Gazzar, MA; Elhenawy, AA; Moustafa, GO; Salim, AE1
Akbulut, N; Atakan, C; Çölok, G; Üstüner, E1
Eissa, SI; Farrag, AM; Galeel, AA1
Brown, MT; Ekman, EF; Greenberg, HS; Schnitzer, TJ; Smith, MD; Spierings, EL; Verburg, KM; West, CR1
Balap, A; Lohidasan, S; Mahadik, K; Sinnathambi, A1
Dial, EJ; Lichtenberger, LM; Moore, JE; Romero, JJ1
Berk, B; Erol, DD; Kupeli, E; Yesilada, E1
Finn, A; Oerther, SC1
Gümüş, C; Ince, F; Inci, MF; Kara, IM; Polat, S1
Balas, M; Plakogiannis, R; Sinnett, M1
Aguilar-Robles, P; Castañeda-Hernández, G; González-García, MP; Ortiz, MI; Ponce-Monter, HA1
Bhise, KS; Bodhankar, SL; Ghosh, P; Kadam, SS; Paradkar, AR1
Chen, WB; Chiang, HN; Wang, LF1
Bonina, F; Puglia, C; Saija, A; Santagati, NA; Tita, B; Tomaino, A1
Backhouse, N; Delporte, C; Feliciano, SA; López-Pérez, JL; Negrete, R1
Berlin, JM; Lifshitz, OH; Taylor, JS1
Backhouse, N; Bórquez, J; Delporte, C; Loyola, A; Salinas, P; San-Martín, A1
Khan, MS; Sharma, V1
Bjørnsson, GA; Haanaes, HR; Skoglund, LA1
Roach, JT; Sufka, KJ1
Ertan, M; Gökhan, N; Küpeli, E; Tozkoparan, B; Yeşilada, E1
Jain, NK; Kulkarni, SK; Sharma, S1
Augustyniak, ME; Cochran, ED; Earl, RA; Ellis, JL; Garvey, DS; Gordon, LJ; Janero, DR; Khanapure, SP; Letts, LG; Melim, TL; Murty, MG; Schwalb, DJ; Selig, WM; Shumway, MJ; Trocha, AM; Young, DV; Zemtseva, IS1
Cao, R; Fragoso, A; Ramírez, HL; Torres-Labandeira, JJ; Valdivia, A; Villalonga, R1
Chen, JS; Huang, SJ; Lin, SC; Lin, YJ; Peng, YS; Wang, LF; Wang, YM1
Amir, M; Javed, SA; Kumar, H1
Efron, N; Holden, BA; Vannas, A1
Ballaron, SJ; Bedord, CJ; De Young, LM; Spires, DA; Wagner, B; Young, JM1
Svendsen, H1
Nielsen, CB1
Adami, A; Benoni, G; Conforti, A; Cuzzolin, L; Del Soldato, P; Lussignoli, S; Menestrina, F1
Briscoe-Dwyer, L; Etzel, JV1
Butrón, F; Galicia, A; Martinez-Zurita, F; Zamora, G1
Bertani, S; Caliceti, P; Conforti, A; Grigolini, L; Lora, S; Lussignoli, S; Marsilio, F; Terzi, M; Veronese, FM1
Akatsu, T; Consolaro, A; Guimarães, SA; Tago, EM1
Bowdler, J; Frerick, H; Kornasoff, D; Montull, E1
Bucci, M; Calignano, A; Cicala, C; Cirino, G; Fiorucci, S; Gerli, R; Ianaro, A; Santucci, L; Wallace, JL1
Fyllingen, G; Haugstvedt, JR; Husby, T; Skoglund, LA1
Aktay, G; Berk, B; Ertan, M; Yesilada, E1
Chiang, HN; Wang, LF; Wu, PC1
Boyle, E; Freeman, PC; Goudie, AC; Mangan, FR; Thomson, M1
Cerutti, S; Forlani, A; Sperandeo, F1
Mörsdorf, K; Wolf, G1
Dixon, ST; Engler, C; Hamilton, EB; Liyanage, SP; Scott, JT; Sturge, RA1
Kitchen, EA; Meacock, SC1
Dorfman, RI1
Calhoun, W; Carlson, RP; Copenhaver, TW; Datko, LJ; Gilman, SC1
Chen, ZN; Deng, RW; Wu, JG1
Carrasco, E; Felipe, A; Grau, M; Guasch, J; Juliá, S; Montero, JL1
Boyle, EA; Crummey, A; Harper, GP; Mangan, FR1
Audette, CA; Burstein, SH; Doyle, SA; Hull, K; Hunter, SA; Latham, V1
Fujimura, H; Hidaka, T; Hiramatsu, Y; Hosoe, K; Watanabe, K; Yamashita, T1
Jenner, PN1
Ehlers, N; Nørrelykke Nissen, J1
Alun-Jones, E; Williams, J1

Trials

13 trial(s) available for naproxen and Anasarca

ArticleYear
Comparison of Clinical Efficacies of Preoperatively Initiated Naproxen Sodium-Codeine Phosphate in Combination, Diclofenac Potassium, and Benzydamine Hydrochloride for Pain, Edema, and Trismus After Extraction of Impacted Lower Third Molar: A Randomized D
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2018, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Benzydamine; Codeine; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans; Male; Molar, Third; Naproxen; Pain, Postoperative; Preoperative Care; Tooth Extraction; Trismus; Young Adult

2018
Comparison of the effect of naproxen, etodolac and diclofenac on postoperative sequels following third molar surgery: a randomised, double-blind, crossover study.
    Medicina oral, patologia oral y cirugia bucal, 2014, Mar-01, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diclofenac; Double-Blind Method; Edema; Etodolac; Female; Humans; Male; Molar, Third; Naproxen; Pain, Postoperative; Tooth Extraction; Tooth, Impacted; Trismus; Young Adult

2014
Efficacy and safety of tanezumab monotherapy or combined with non-steroidal anti-inflammatory drugs in the treatment of knee or hip osteoarthritis pain.
    Annals of the rheumatic diseases, 2015, Volume: 74, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Arthralgia; Arthroplasty, Replacement; Celecoxib; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans; Hypesthesia; Male; Middle Aged; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Paresthesia; Pyrazoles; Sulfonamides; Treatment Outcome

2015
Analgesic and anti-inflammatory effects of oxaprozin and naproxen sodium after removal of impacted lower third molars: a randomized, double-blind, placebo-controlled crossover study.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2010, Volume: 68, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method; Edema; Face; Female; Humans; Male; Mandible; Molar, Third; Naproxen; Oxaprozin; Pain, Postoperative; Placebos; Propionates; Prospective Studies; Range of Motion, Articular; Tooth, Impacted; Trismus; Young Adult

2010
Naproxen 500 mg bid versus acetaminophen 1000 mg qid: effect on swelling and other acute postoperative events after bilateral third molar surgery.
    Journal of clinical pharmacology, 2003, Volume: 43, Issue:8

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Confidence Intervals; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Edema; Female; Humans; Male; Molar, Third; Naproxen; Pain, Postoperative; Postoperative Complications; Tooth Extraction

2003
Effect of prostaglandin-inhibitor naproxen on the corneal swelling response to hydrogel contact lens wear.
    Acta ophthalmologica, 1984, Volume: 62, Issue:5

    Topics: Adolescent; Adult; Clinical Trials as Topic; Contact Lenses; Corneal Diseases; Edema; Female; Humans; Male; Naproxen; Prostaglandin Antagonists

1984
[The effect of naproxen suppositories on postoperative pain and edema compared with oxyphenbutazone and placebo. A single blind pilot project in rheumatoid surgery].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1982, Jan-20, Volume: 102, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Edema; Humans; Joints; Male; Middle Aged; Naproxen; Oxyphenbutazone; Pain, Postoperative; Pilot Projects; Postoperative Complications; Suppositories

1982
Single blind study to evaluate the efficacy and safety of naproxen gel compared with diclophenac emulgel in the treatment of soft tissue injuries.
    Proceedings of the Western Pharmacology Society, 1994, Volume: 37

    Topics: Adult; Contusions; Diclofenac; Edema; Female; Gels; Humans; Male; Middle Aged; Naproxen; Pain Measurement; Single-Blind Method; Soft Tissue Injuries; Sprains and Strains

1994
Aceclofenac is a well-tolerated alternative to naproxen in the treatment of osteoarthritis.
    Clinical rheumatology, 1997, Volume: 16, Issue:1

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Diclofenac; Double-Blind Method; Drug Administration Schedule; Edema; Erythema; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Range of Motion, Articular; Treatment Outcome

1997
Acute postoperative swelling after hand surgery: an exploratory, double-blind, randomised study with paracetamol, naproxen, and placebo.
    Scandinavian journal of plastic and reconstructive surgery and hand surgery, 2001, Volume: 35, Issue:1

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Carpal Tunnel Syndrome; Double-Blind Method; Dupuytren Contracture; Edema; Female; Hand; Humans; Inflammation; Male; Middle Aged; Naproxen

2001
Nabumetone in the treatment of skin and soft tissue injury.
    The American journal of medicine, 1987, Oct-30, Volume: 83, Issue:4B

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Clinical Trials as Topic; Double-Blind Method; Edema; Female; Humans; Ibuprofen; Joints; Male; Middle Aged; Nabumetone; Naproxen; Pain; Random Allocation; Skin; Sprains and Strains

1987
No additive effect of tranexamic acid and naproxen on corneal deswelling. A study on oedema after uncomplicated intracapsular cataract extraction with anterior chamber lens implantation.
    Acta ophthalmologica, 1986, Volume: 64, Issue:3

    Topics: Aged; Cataract Extraction; Clinical Trials as Topic; Cornea; Corneal Diseases; Cyclohexanecarboxylic Acids; Edema; Female; Humans; Lenses, Intraocular; Male; Naproxen; Postoperative Complications; Tranexamic Acid

1986
Naproxen (Naprosyn) and ketoprofen (Orudis).
    Drug and therapeutics bulletin, 1974, Mar-29, Volume: 12, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzophenones; Clinical Trials as Topic; Edema; Humans; Ketoprofen; Naphthaleneacetic Acids; Naproxen

1974

Other Studies

75 other study(ies) available for naproxen and Anasarca

ArticleYear
Synthesis and antiinflammatory activity of cis-4,5,6,7,8,8a,9-hexahydro-alpha-methyl-5H-fluorene-2-acetic acid.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Arthus Reaction; Edema; Fluorenes; Magnetic Resonance Spectroscopy; Molecular Conformation; Rabbits; Rats; Stereoisomerism

1977
Synthesis and antiinflammatory activity of 6,11-dihydro-11-oxodibenzo[b,e]thiepinalkanoic acids and related compounds.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:10

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Chemical Phenomena; Chemistry; Dibenzothiepins; Dogs; Edema; Female; Gossypium; Granuloma; Male; Mice; Quinones; Rats; Stomach Ulcer; Structure-Activity Relationship

1978
Cycloalkanoindoles. 1. Syntheses and antiinflammatory actions of some acidic tetrahydrocarbazoles, cyclopentindoles, and cycloheptindoles.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Cycloheptanes; Cyclopentanes; Edema; Indoles; Rats; Stomach Ulcer; Structure-Activity Relationship

1976
1,2-Dihydro-1-oxopyrrolo[3,2,1-kl]phenothiazine-2-carboxamides and congeners, dual cyclooxygenase/5-lipoxygenase inhibitors with antiinflammatory activity.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cell Line; Cyclooxygenase Inhibitors; Edema; Indicators and Reagents; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Models, Molecular; Molecular Structure; Prostaglandin Antagonists; Pyrroles; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazines

1990
Synthesis and antiinflammatory and analgesic activity of 5-aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-ca rboxyl ic acids and 1-methyl-4-(methylthio)-5-aroylpyrrole-2-acetic acids.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Acetates; Analgesia; Animals; Aspirin; Benzoquinones; Carboxylic Acids; Carrageenan; Chemical Phenomena; Chemistry; Edema; Inflammation; Mice; Molecular Structure; Pain Measurement; Phenylbutazone; Pyrroles; Quinones; Rats

1989
Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthus Reaction; Chemical Phenomena; Chemistry; Edema; Guinea Pigs; Hypersensitivity, Delayed; Male; Mice; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Inbred Strains

1982
Nonsteroidal antiinflammatory agents. 14. Synthesis and pharmacological profile of 6-chloro-5-(cyclopentylmethyl)indan-1-carboxylic acid.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Edema; Indans; Indenes; Male; Rats; Rats, Inbred Strains

1984
1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents.
    Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Gastrointestinal Diseases; Humans; Imidazoles; Isoenzymes; Membrane Proteins; Mice; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Rats; Structure-Activity Relationship; Sulfonamides; Sulfones

1997
New cyclooxygenase-2/5-lipoxygenase inhibitors. 1. 7-tert-buty1-2,3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: discovery and variation of the 5-keto substituent.
    Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Benzofurans; Blood Platelets; Carrageenan; Cyclooxygenase Inhibitors; Edema; Humans; Lipoxygenase Inhibitors; Male; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley

1998
New cyclooxygenase-2/5-lipoxygenase inhibitors. 2. 7-tert-butyl-2,3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: variations of the dihydrobenzofuran ring.
    Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzofurans; Blood Platelets; Carrageenan; Cyclooxygenase Inhibitors; Edema; Humans; Lipoxygenase Inhibitors; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley

1998
New cyclooxygenase-2/5-lipoxygenase inhibitors. 3. 7-tert-butyl-2, 3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: variations at the 5 position.
    Journal of medicinal chemistry, 1998, Aug-27, Volume: 41, Issue:18

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Enzyme Inhibitors; Humans; Isoenzymes; Lipoxygenase Inhibitors; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Structure-Activity Relationship

1998
Selective cyclooxygenase-2 inhibitors: heteroaryl modified 1,2-diarylimidazoles are potent, orally active antiinflammatory agents.
    Journal of medicinal chemistry, 2000, Aug-10, Volume: 43, Issue:16

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dogs; Edema; Gastrointestinal Hemorrhage; Humans; Hyperalgesia; Imidazoles; Intestines; Isoenzymes; Membrane Proteins; Mice; Nitriles; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Stomach; Structure-Activity Relationship; Sulfonamides

2000
Synthesis and biological evaluation of quinoline salicylic acids as P-selectin antagonists.
    Journal of medicinal chemistry, 2007, Jan-11, Volume: 50, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Biological Availability; Cytochrome P-450 Enzyme Inhibitors; Databases, Factual; Edema; Humans; Hydroxyquinolines; In Vitro Techniques; Leukocyte Rolling; Male; P-Selectin; Quinolines; Rats; Rats, Sprague-Dawley; Salicylates; Structure-Activity Relationship

2007
Potential anti-inflammatory actions of the elmiric (lipoamino) acids.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Alanine; Animals; Anti-Inflammatory Agents; Cell Line; Cell Proliferation; Chromatography, Thin Layer; Drug Evaluation, Preclinical; Edema; Fatty Acids; Glycine; Indicators and Reagents; Macrophages; Magnetic Resonance Spectroscopy; Male; Mice; Phorbol Esters; Prostaglandin Antagonists; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

2007
Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoates; Biological Availability; Bronchoconstriction; Calorimetry; Carrageenan; Cell Line; Cyclooxygenase 2 Inhibitors; Edema; Group IV Phospholipases A2; Humans; In Vitro Techniques; Isoenzymes; Male; Mice; Protein Binding; Rats; Rats, Sprague-Dawley; Sheep; Structure-Activity Relationship; Sulfonamides

2008
Benzophenone-N-ethyl piperidine ether analogues--synthesis and efficacy as anti-inflammatory agent.
    Bioorganic & medicinal chemistry letters, 2009, Apr-01, Volume: 19, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Benzophenones; Carrageenan; Edema; Mice; Piperidines; Prostaglandins

2009
Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti-inflammatory, and ulcerogenicity index studies.
    Journal of medicinal chemistry, 2011, Mar-10, Volume: 54, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase Inhibitors; Edema; Esters; Gastric Mucosa; Humans; Hydroxamic Acids; Ibuprofen; Indomethacin; Male; Naproxen; Nitric Oxide Donors; Nitrogen Oxides; Prodrugs; Rats; Rats, Sprague-Dawley; Stereoisomerism; Stomach Ulcer; Structure-Activity Relationship

2011
Fragment-based design, docking, synthesis, biological evaluation and structure-activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors.
    European journal of medicinal chemistry, 2012, Volume: 47, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Design; Edema; Female; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Models, Molecular; Structure-Activity Relationship; Thiazolidines

2012
Synthesis and pharmacological evaluation of pyrazolo[4,3-c]cinnoline derivatives as potential anti-inflammatory and antibacterial agents.
    European journal of medicinal chemistry, 2012, Volume: 57

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase 2; Edema; Escherichia coli; Heterocyclic Compounds, 2-Ring; Inflammation; Lipid Peroxidation; Microbial Sensitivity Tests; Molecular Docking Simulation; Naproxen; Pseudomonas aeruginosa; Pyrazoles; Rats; Rats, Wistar; Staphylococcus aureus; Structure-Activity Relationship; Ulcer

2012
Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents.
    Bioorganic & medicinal chemistry, 2013, Jan-15, Volume: 21, Issue:2

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Edema; Gram-Negative Bacteria; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Thiazoles

2013
Design of novel potent antihyperlipidemic agents with antioxidant/anti-inflammatory properties: exploiting phenothiazine's strong antioxidant activity.
    Journal of medicinal chemistry, 2014, Mar-27, Volume: 57, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Atherosclerosis; Biphenyl Compounds; Carrageenan; Cholesterol, Dietary; Cyclooxygenase Inhibitors; Diet, High-Fat; Drug Design; Edema; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Hypolipidemic Agents; In Vitro Techniques; Indicators and Reagents; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Male; Mice; Microsomes; Phenothiazines; Picrates; Rats

2014
Synthesis, antinociceptive and anti-inflammatory effects of porphyrins.
    Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10

    Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Disease Models, Animal; Edema; Erythrocytes; Hemolysis; Indomethacin; Male; Mice; Naproxen; Nociception; Pain; Pain Measurement; Porphyrins; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate

2015
Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies.
    Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Drug Design; Edema; Humans; Inflammation; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Naproxen; Nociception; Pain; Pain Measurement; Structure-Activity Relationship; Thiazoles; Thiones; Triazoles

2015
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid

2015
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
    Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3

    Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hyperlipidemias; Hypolipidemic Agents; Morpholines; Rats; Triglycerides

2016
Synthesis and biological properties of aryl methyl sulfones.
    Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carrageenan; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Edema; Humans; Male; Mice; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Sulfones; Thermodynamics

2018
Synthesis, characterization, and in vivo pharmacological evaluation of novel mannich bases derived from 1,2,4-triazole containing a naproxen moiety.
    Bioorganic chemistry, 2020, Volume: 100

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Drug Design; Edema; Humans; Male; Mannich Bases; Mice, Inbred BALB C; Molecular Docking Simulation; Naproxen; Pain; Triazoles

2020
New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5
    Molecules (Basel, Switzerland), 2021, Jan-27, Volume: 26, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Female; Humans; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Molecular Docking Simulation; Naproxen; Structure-Activity Relationship; Triazoles

2021
Evaluation of anti-inflammatory and ulcerogenic potential of zinc-ibuprofen and zinc-naproxen complexes in rats.
    Inflammopharmacology, 2017, Volume: 25, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Carrageenan; Edema; Gastric Mucosa; Ibuprofen; Inflammation; Male; Naproxen; Organometallic Compounds; Rats; Rats, Wistar; Zinc; Zinc Compounds

2017
The efficacy of hyaluronic acid in postextraction sockets of impacted third molars: A pilot study.
    Nigerian journal of clinical practice, 2017, Volume: 20, Issue:12

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Edema; Female; Humans; Hyaluronic Acid; Male; Molar, Third; Naproxen; Pain Measurement; Pain, Postoperative; Pilot Projects; Prospective Studies; Tooth Extraction; Tooth, Impacted; Treatment Outcome; Trismus; Visual Analog Scale

2017
Enhanced delivery of naproxen to the viable epidermis from an activated poly N-isopropylacrylamide (PNIPAM) Nanogel: Skin penetration, modulation of COX-2 expression and rat paw oedema.
    Nanomedicine : nanotechnology, biology, and medicine, 2018, Volume: 14, Issue:7

    Topics: Acrylamides; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 2; Drug Delivery Systems; Edema; Epidermal Cells; Epidermis; Gene Expression Regulation; Male; Nanogels; Naproxen; Polyethylene Glycols; Polyethyleneimine; Polymers; Rats; Rats, Wistar; Skin

2018
Synthesis, comparative docking, and pharmacological activity of naproxen amino acid derivatives as possible anti-inflammatory and analgesic agents.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Amino Acids; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Molecular Docking Simulation; Molecular Structure; Naproxen; Rats; Rats, Wistar

2019
Non-carboxylic analogues of aryl propionic acid: synthesis, anti-inflammatory, analgesic, antipyretic and ulcerogenic potential.
    Drug research, 2014, Volume: 64, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Carrageenan; Disease Models, Animal; Edema; Fever; Inflammation; Male; Mice; Naphthalenes; Naproxen; Pain; Propionates; Rats; Rats, Wistar; Ulcer

2014
Herb-drug interaction of Andrographis paniculata (Nees) extract and andrographolide on pharmacokinetic and pharmacodynamic of naproxen in rats.
    Journal of ethnopharmacology, 2017, Jan-04, Volume: 195

    Topics: Administration, Oral; Andrographis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arthritis, Experimental; Chromatography, High Pressure Liquid; Diterpenes; Edema; Female; Freund's Adjuvant; Half-Life; Herb-Drug Interactions; Hyperalgesia; Metabolic Clearance Rate; Naproxen; Nociception; Nociceptive Pain; Pain Threshold; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar

2017
Naproxen-PC: a GI safe and highly effective anti-inflammatory.
    Inflammopharmacology, 2009, Volume: 17, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Edema; Gastrointestinal Hemorrhage; Glycine max; Inflammation; Lecithins; Naproxen; Rats; Synovial Fluid

2009
Design and synthesis of some (S)-2-(6-methoxynaphthalen-2-yl)-N-substituted ethyl propanamide derivatives as potent non-ulcerogenic anti-inflammatory and analgesic agents.
    Arzneimittel-Forschung, 2009, Volume: 59, Issue:4

    Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Carrageenan; Drug Delivery Systems; Drug Design; Edema; Foot; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Naphthalenes; Naproxen; Pain; Spectrophotometry, Infrared; Stomach Ulcer; Structure-Activity Relationship

2009
Can L(+)-lactate be used as a marker of experimentally induced inflammation in rats?
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2010, Volume: 59, Issue:4

    Topics: Animals; Arthritis, Experimental; Biomarkers; Carrageenan; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Freund's Adjuvant; Joints; Lactic Acid; Lactones; Male; Naproxen; Rats; Rats, Sprague-Dawley; Sulfones

2010
Periorbital edema associated with separate courses of ibuprofen and naproxen.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2010, Jun-01, Volume: 67, Issue:11

    Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Edema; Eye Diseases; Female; Humans; Ibuprofen; Naproxen; Osteoarthritis

2010
Synergistic effect of the interaction between naproxen and citral on inflammation in rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Dec-15, Volume: 18, Issue:1

    Topics: Acyclic Monoterpenes; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Synergism; Edema; Herb-Drug Interactions; Inflammation; Male; Monoterpenes; Naproxen; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Stomach Diseases

2010
Reduced ulcerogenic potential and antiarthritic effect of chitosan-naproxen sodium complexes.
    AAPS PharmSciTech, 2012, Volume: 13, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Antirheumatic Agents; Chitosan; Drug Combinations; Edema; Female; Naproxen; Rats; Rats, Wistar; Sodium; Stomach Ulcer; Treatment Outcome

2012
Synthesis and properties of a naproxen polymeric prodrug.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:8

    Topics: Animals; Carrageenan; Catalysis; Edema; Esterases; Female; Hydrolysis; Kinetics; Lipase; Magnetic Resonance Spectroscopy; Naproxen; Polymers; Prodrugs; Rats; Rats, Wistar

2002
Oligoethylene ester derivatives of ketoprofen, naproxen and diclofenac as oral prodrugs: a pharmacological evaluation.
    Die Pharmazie, 2002, Volume: 57, Issue:8

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Edema; Esters; Hydrolysis; Ketoprofen; Male; Mice; Naproxen; Pain Measurement; Pharmaceutical Vehicles; Polyethylene Glycols; Prodrugs; Rats; Rats, Sprague-Dawley; Stomach Ulcer

2002
Bioactive phenolic derivatives from Acaena splendens methanol extract.
    Phytotherapy research : PTR, 2002, Volume: 16, Issue:6

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Carrageenan; Catechin; Chromones; Edema; Female; Fever; Flavonoids; Glucosides; Guinea Pigs; Hindlimb; Inflammation; Kaempferols; Magnetic Resonance Spectroscopy; Male; Medicine, Traditional; Molecular Structure; Naproxen; Phenols; Phytotherapy; Plant Extracts; Rabbits; Rosaceae

2002
A 52-year-old man with sudden onset of a facial rash.
    Cleveland Clinic journal of medicine, 2002, Volume: 69, Issue:10

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Eruptions; Edema; Facial Dermatoses; Genital Diseases, Male; Humans; Male; Middle Aged; Naproxen; Nonprescription Drugs; Patch Tests; Prednisone

2002
Pharmaco-toxicological study of diterpenoids.
    Bioorganic & medicinal chemistry, 2003, Apr-03, Volume: 11, Issue:7

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Apiaceae; Arachidonic Acid; Chile; Diterpenes; Dose-Response Relationship, Drug; Edema; Female; Indicators and Reagents; Indomethacin; Lipoxygenase Inhibitors; Male; Mice; Molecular Conformation; Naproxen; Pain Measurement; Plants, Medicinal; Structure-Activity Relationship; Sulfonamides; Tetradecanoylphorbol Acetate

2003
Prodrugs and mutual prodrugs: synthesis of some new pyrazolone and oxadiazole analogues of a few non-steroidal anti-inflammatory drugs.
    Die Pharmazie, 2003, Volume: 58, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chromatography, Thin Layer; Edema; Female; Indicators and Reagents; Male; Mice; Naproxen; Oxadiazoles; Pain Measurement; Prodrugs; Pyrazoles; Rats

2003
Characterization of the chick carrageenan response.
    Brain research, 2003, Dec-24, Volume: 994, Issue:2

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Chickens; Cyclooxygenase Inhibitors; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Edema; Hyperalgesia; Inflammation; Morphine; Naproxen; Pain Measurement; Reaction Time; Time Factors

2003
Synthesis, characterization and antiinflammatory-analgesic properties of 6-(alpha-amino-4-chlorobenzyl)thiazolo [3,2-b]-1,2,4-triazol-5-ols.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:1

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Capillary Permeability; Carrageenan; Chemical Phenomena; Chemistry, Physical; Edema; Foot; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mice; Models, Molecular; Molecular Conformation; Naproxen; Pain; Spectroscopy, Fourier Transform Infrared; Stomach Ulcer; Structure-Activity Relationship; Thiazoles; Triazoles

2004
Possible analgesic and anti-inflammatory interactions of aspartame with opioids and NSAIDs.
    Indian journal of experimental biology, 2005, Volume: 43, Issue:6

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspartame; Carrageenan; Drug Interactions; Edema; Inflammation; Mice; Morphine; Naproxen; Narcotics; Pain; Pain Measurement; Pentazocine; Rats; Rats, Wistar; Sulfonamides; Sweetening Agents; Time Factors

2005
NMI-1182, a gastro-protective cyclo-oxygenase-inhibiting nitric oxide donor.
    Inflammopharmacology, 2005, Volume: 12, Issue:5-6

    Topics: Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Edema; Gastric Mucosa; Humans; In Vitro Techniques; Inflammation; Male; Molecular Structure; Naphthalenes; Naproxen; Neutrophil Infiltration; Nitric Oxide Donors; Protective Agents; Rats; Rats, Sprague-Dawley; Vasodilation

2005
Cyclodextrin-grafted polysaccharides as supramolecular carrier systems for naproxen.
    Bioorganic & medicinal chemistry letters, 2006, Mar-15, Volume: 16, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Carboxymethylcellulose Sodium; Carcinogens; Carrageenan; Dextrans; Drug Carriers; Edema; Male; Mannans; Naproxen; Oxidation-Reduction; Periodic Acid; Rats; Rats, Wistar

2006
Chondroitin sulfate-based anti-inflammatory macromolecular prodrugs.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2006, Volume: 29, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Carrageenan; Chemical Phenomena; Chemistry, Physical; Chondroitin ABC Lyase; Chondroitin Sulfates; Edema; Excipients; Hydrolysis; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Male; Naproxen; Polyethylene Glycols; Prodrugs; Rats; Rats, Wistar; Solubility; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared

2006
Non-carboxylic analogues of naproxen: design, synthesis, and pharmacological evaluation of some 1,3,4-oxadiazole/thiadiazole and 1,2,4-triazole derivatives.
    Archiv der Pharmazie, 2007, Volume: 340, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Drug Design; Edema; Liver; Liver Function Tests; Male; Mice; Molecular Structure; Naproxen; Oxadiazoles; Pain; Rats; Stomach Ulcer; Thiadiazoles; Triazoles

2007
The mouse ear inflammatory response to topical arachidonic acid.
    The Journal of investigative dermatology, 1984, Volume: 82, Issue:4

    Topics: Administration, Topical; Animals; Arachidonic Acid; Arachidonic Acids; Cell Division; DNA; Dose-Response Relationship, Drug; Ear, External; Edema; Erythema; Female; Inflammation; Mice; Naproxen; Prostaglandin-Endoperoxide Synthases; Skin; Vasodilation

1984
Prostaglandin inhibition and central corneal thickness after cataract extraction.
    Acta ophthalmologica, 1982, Volume: 60, Issue:2

    Topics: Adult; Aged; Cataract Extraction; Cornea; Corneal Diseases; Edema; Humans; Naproxen; Prostaglandin Antagonists

1982
Anti-inflammatory potency and gastrointestinal toxicity of a new compound, nitronaproxen.
    Pharmacological research, 1995, Volume: 31, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Digestive System; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Female; Male; Naproxen; Rats; Rats, Sprague-Dawley; Stomach Ulcer

1995
Dyspnea and periorbital edema following an increase in naproxen dose.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:9

    Topics: Adult; Dyspnea; Edema; Humans; Male; Naproxen; Orbital Diseases

1994
Anti-inflammatory activity of polyphosphazene-based naproxen slow-release systems.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:5

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Implants; Edema; Freund's Adjuvant; Male; Naproxen; Organophosphorus Compounds; Polymers; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley

1996
Assessment of the antiexudative and antiproliferative activities of non-steroidal anti-inflammatory drugs in inflammatory models developed in rats by subcutaneous implantation of bacterial cell walls from the dental plaque.
    Inflammation, 1996, Volume: 20, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cell Division; Cell Wall; Child; Dental Plaque; DNA Replication; Duodenum; Edema; Exudates and Transudates; Granuloma; Growth Inhibitors; Humans; Ibuprofen; Indomethacin; Inflammation; Intestinal Mucosa; Naproxen; Rats; Sulindac

1996
NO-naproxen modulates inflammation, nociception and downregulates T cell response in rat Freund's adjuvant arthritis.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Dose-Response Relationship, Drug; Edema; Flow Cytometry; Hindlimb; Inflammation; Interleukin-1; Male; Naproxen; Nitric Oxide; Nociceptors; Pain; Pain Measurement; Rats; Rats, Inbred Lew; Receptors, Interleukin-2; T-Lymphocytes; Thymidine; Time Factors; Tumor Necrosis Factor-alpha

2000
Synthesis and pharmacological activities of some new 2-[1-(6-methoxy-2-naphthyl)ethyl]-6-(substituted)benzylidene thiazolo[3,2-b]-1,2,4-triazole-5(6H)-one derivatives.
    Die Pharmazie, 2001, Volume: 56, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chromatography, Thin Layer; Cyclization; Edema; Female; Gastric Mucosa; Male; Mice; Naphthalenes; Naproxen; Stomach Ulcer; Thiazoles

2001
Kinetics and hydrolysis mechanism of polymeric prodrugs containing ibuprofen, ketoprofen, and naproxen as pendent agents.
    Journal of biomaterials science. Polymer edition, 2002, Volume: 13, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Stability; Edema; Female; Hydrogen-Ion Concentration; Hydrolysis; Ibuprofen; Ketoprofen; Kinetics; Methacrylates; Naproxen; Polymers; Prodrugs; Rats; Rats, Wistar; Solubility; Treatment Outcome

2002
The role of copper in preventing gastrointestinal damage by acidic anti-inflammatory drugs.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:12

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chelating Agents; Copper; Edema; Female; In Vitro Techniques; Indomethacin; Ketoprofen; Male; Naproxen; Niflumic Acid; Peptic Ulcer; Prostaglandins E; Pyrroles; Rats

1976
[Anti-edematous, anti-inflammatory and analgesics activity of fentiazac, naproxen and diclofenac sodium].
    Bollettino chimico farmaceutico, 1977, Volume: 116, Issue:7

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Edema; Mice; Naproxen; Peritonitis; Phenylacetates; Pleurisy; Rats; Thiazoles

1977
[On the efficiency of new antiinflammatory agents. A comparative study (author's transl)].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Benzylidene Compounds; Carrageenan; Diclofenac; Edema; Fenoprofen; In Vitro Techniques; Indenes; Indomethacin; Ketoprofen; Naproxen; Phenylbutazone; Protease Inhibitors; Rats

1977
Multi-centre trial of naproxen and phenylbutazone in acute gout.
    Advances in experimental medicine and biology, 1977, Volume: 76B

    Topics: Adult; Age Factors; Aged; Body Fluids; Edema; Female; Gout; Humans; Male; Middle Aged; Naphthaleneacetic Acids; Naproxen; Phenylbutazone

1977
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration.
    Agents and actions, 1976, Volume: 6, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen; Indomethacin; Ketoprofen; Leukocytes; Male; Methotrexate; Naproxen; Phenylbutazone; Pleurisy; Rats

1976
Chemistry and pharmacology of naproxen.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:2A

    Topics: Administration, Oral; Adrenalectomy; Animals; Aspirin; Carrageenan; Drug Evaluation, Preclinical; Edema; Female; Fever; Granuloma; Indomethacin; Male; Mice; Naphthaleneacetic Acids; Naproxen; Phenylbutazone; Pressure; Quinones; Rats; Yeast, Dried

1975
Interaction studies of tilomisole, aspirin, and naproxen in acute and chronic inflammation with assessment of gastrointestinal irritancy in the rat.
    Agents and actions, 1992, Volume: 36, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Benzimidazoles; Bone and Bones; Carrageenan; Connective Tissue; Drug Interactions; Edema; Gastrointestinal Diseases; Inflammation; Male; Naproxen; Rats; Rats, Sprague-Dawley

1992
Synthesis, characterization, and antiinflammatory activity of naproxen complexes with rare earth (III).
    Journal of inorganic biochemistry, 1992, Volume: 47, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry, Physical; Croton Oil; Edema; Formaldehyde; Magnetic Resonance Spectroscopy; Male; Metals; Molecular Structure; Naproxen; Rats; Solubility; Spectrophotometry; Spectrophotometry, Infrared

1992
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoquinones; Capillary Permeability; Carrageenan; Diclofenac; Edema; Female; Granuloma; Indomethacin; Male; Mice; Naproxen; Pain; Phenylbutazone; Pleurisy; Rats; Rats, Inbred Strains; Silver Nitrate; Stomach Ulcer; Synovitis

1991
Inhibition of arachidonic acid-induced ear oedema as a model for assessing topical anti-inflammatory compounds.
    Agents and actions, 1987, Volume: 20, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Edema; Free Radicals; Histamine Release; Indomethacin; Lipoxygenase Inhibitors; Mast Cells; Mathematics; Mice; Naproxen

1987
Antagonism to the actions of platelet activating factor by a nonpsychoactive cannabinoid.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cannabinoids; Dronabinol; Edema; Female; Hydroxyeicosatetraenoic Acids; Mice; Naproxen; Platelet Activating Factor; Structure-Activity Relationship

1989
Analgesic and anti-inflammatory activities in rats of alpha-(3,5-di-t-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), and its intestinal damage.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:10

    Topics: 4-Butyrolactone; Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capillary Permeability; Edema; Furans; Ibuprofen; Indomethacin; Intestinal Diseases; Lethal Dose 50; Male; Naproxen; Rats; Rats, Inbred Strains

1986
Hyponatremia and fluid retention in a neonate associated with maternal naproxen overdosage.
    Journal of toxicology. Clinical toxicology, 1986, Volume: 24, Issue:3

    Topics: Adult; Edema; Female; Humans; Hyponatremia; Infant, Newborn; Maternal-Fetal Exchange; Naproxen; Pregnancy

1986