naproxen has been researched along with Adjuvant Arthritis in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (29.55) | 18.7374 |
| 1990's | 11 (25.00) | 18.2507 |
| 2000's | 8 (18.18) | 29.6817 |
| 2010's | 10 (22.73) | 24.3611 |
| 2020's | 2 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Ackrell, J; Antonio, Y; Franco, F; Landeros, R; Leon, A; Maddox, ML; Muchowski, JM; Nelson, PH; Rooks, WH; Roszkowski, AP; Wallach, MB | 1 |
| Cheng, CC; Miyai, K; Robins, RK; Tolman, RL | 1 |
| Millonig, RC; Rovnyak, GC; Schwartz, J; Shu, V | 1 |
| Boettcher, I; Elger, W; Kirsch, G; Siegmund, F; Wachtel, H | 1 |
| Ariyan, ZS; Fogt, SW; Heilman, RD; Matthews, RJ; Powers, LJ; Rippin, DJ | 1 |
| Calhoun, W; Carlson, RP; Crossley, R; Datko, LJ; Dietrich, S; Heatherington, K; Marshall, LA; Meade, PJ; Opalko, A; Shepherd, RG | 1 |
| Bertenshaw, SR; Burton, EG; Carter, JS; Cogburn, JN; Collins, PW; Docter, S; Graneto, MJ; Gregory, SA; Isakson, PC; Koboldt, CM; Lee, LF; Malecha, JW; Miyashiro, JM; Penning, TD; Perkins, WE; Rogers, RS; Rogier, DJ; Seibert, K; Talley, JJ; Veenhuizen, AW; Yu, SS; Zhang, YY | 1 |
| Casler, JJ; Collins, PW; Gregory, SA; Isakson, PC; Khanna, IK; Koboldt, CM; Koszyk, FJ; Masferrer, JL; Perkins, WE; Seibert, K; Veenhuizen, AW; Weier, RM; Xu, XD; Yu, Y; Zhang, YY | 1 |
| Beleta, J; Cardelús, I; Crespo, MI; Feixas, J; Godessart, N; Heredia, A; Huerta, JM; Ibarzo, J; Jiménez, JM; López, M; Miralpeix, M; Palacios, JM; Puig, C; Puig, J; Ryder, H; Segarra, V; Soca, L | 1 |
| Cogburn, JN; Collins, PW; Huff, RM; Isakson, PC; Khanna, IK; Koboldt, CM; Koszyk, FJ; Masferrer, JL; Perkins, WE; Seibert, K; Veenhuizen, AW; Weier, RM; Xu, X; Yang, DC; Yu, Y; Yuan, J; Zhang, YY | 1 |
| Bedard, PW; Camphausen, RT; DeBernardo, S; Janz, K; Kaila, N; Keith, JC; Nickerson-Nutter, C; Shilling, A; Tam, S; Tsao, DH; Wang, Q; Young-Sciame, R | 1 |
| Abraham, WM; Albert, L; Behnke, ML; Chen, L; Clark, JD; Donahue, F; Foley, MA; Goodwin, DG; Hegen, M; Hu, B; Hu, Y; Ipek, M; Keith, J; Kirincich, SJ; Ku, MS; Lee, KL; McKew, JC; Michalak, R; Murphy, EA; Nickerson-Nutter, CL; Ramarao, MK; Shen, MW; Sum, FW; Tam, S; Thakker, P; Thomason, J; Williams, C; Wooder, L; Wu, K; Xu, X | 1 |
| Alonso-Castro, AJ; Campos-Xolalpa, N; Hernández-Munive, A; Pérez-González, C; Pérez-Gutiérrez, S; Zapata-Morales, JR | 1 |
| Bao, Z; Chen, L; Chu, Z; Gong, G; Gu, S; He, G; Huang, J; Huang, L; Shen, H; Wan, S; Wu, Y; Xu, Y; Zhang, S; Zhu, Q; Zou, Y | 1 |
| Abdel-Daim, MM; Akhtar, MF; Alsharif, KF; Saleem, A; Zubair, S | 1 |
| Almon, RR; Chen, X; DuBois, DC; Jusko, WJ; Li, X; Song, D | 1 |
| Bordy, R; Demougeot, C; Prati, C; Totoson, P; Verhoeven, F; Wendling, D | 1 |
| Andreassen, KV; Dąbrowska, A; Ding, M; Henriksen, K; Karsdal, MA; Katri, A; Löfvall, H; Thudium, CS | 1 |
| Dief, AE; Mostafa, DK; Sharara, GM; Zeitoun, TH | 1 |
| Balap, A; Lohidasan, S; Mahadik, K; Sinnathambi, A | 1 |
| Almon, RR; DuBois, DC; Jusko, WJ; Li, X | 2 |
| Butt, YK; Lee, CH; Lo, SC; Wong, MS | 1 |
| Finn, A; Oerther, SC | 1 |
| Caliendo, G; Cirino, G; Santagada, V; Wallace, JL | 1 |
| Gillet, P; Jaffré, B; Laugier, P; Loeuille, D; Netter, P; Saïed, A; Watrin, A | 1 |
| Cirino, G; Di Lorenzo, A; Farneti, S; Fiorucci, S; Morelli, A; Renga, B | 1 |
| Klicius, J; Martel, RR; Metcalf, G | 1 |
| Klicius, J; Martel, RR; Metcalf, G; Rona, GA | 1 |
| Ackerman, NR; Kappas, K; Maloney, P | 1 |
| de Medicis, R; Lussier, A | 1 |
| Arumugham, R; Bose, SM | 1 |
| Adami, A; Benoni, G; Conforti, A; Cuzzolin, L; Del Soldato, P; Lussignoli, S; Menestrina, F | 1 |
| Medvedeff, ED; Nickerson-Nutter, CL | 1 |
| Bertani, S; Caliceti, P; Conforti, A; Grigolini, L; Lora, S; Lussignoli, S; Marsilio, F; Terzi, M; Veronese, FM | 1 |
| Caruso, FS; Frenk, H; Lu, J; Mao, J; Mayer, DJ; Price, DD | 1 |
| Antoon, JS; Perry, MA; Walker, JS; Wilson, JL | 1 |
| Bucci, M; Calignano, A; Cicala, C; Cirino, G; Fiorucci, S; Gerli, R; Ianaro, A; Santucci, L; Wallace, JL | 1 |
| Ackerman, NR; Genant, H; Maloney, P; Rooks, WH; Shott, L; West, E | 1 |
| Datko, LJ; Jones, RC | 1 |
| Bendele, AM; Benslay, DN; Hom, JT; Lee, SJ; Lindstrom, TD; Naismith, RW; Ruterbories, KJ; Spaethe, SM | 1 |
| Calhoun, W; Carlson, RP; Copenhaver, TW; Datko, LJ; Gilman, SC | 1 |
| Carrasco, E; Felipe, A; Grau, M; Guasch, J; Juliá, S; Montero, JL | 1 |
| Fujimura, H; Hidaka, T; Hiramatsu, Y; Hosoe, K; Watanabe, K; Yamashita, T | 1 |
44 other study(ies) available for naproxen and Adjuvant Arthritis
| Article | Year |
|---|---|
Synthesis and antiinflammatory activity of 6,11-dihydro-11-oxodibenzo[b,e]thiepinalkanoic acids and related compounds.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Chemical Phenomena; Chemistry; Dibenzothiepins; Dogs; Edema; Female; Gossypium; Granuloma; Male; Mice; Quinones; Rats; Stomach Ulcer; Structure-Activity Relationship | 1978 |
Synthesis and antiinflammatory activity of 6-oxo-1-(beta-D-ribofuranosyl)nocotinic acid and related derivatives.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Methods; Nicotinic Acids; Rats; Ribonucleosides | 1978 |
Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthus Reaction; Chemical Phenomena; Chemistry; Edema; Guinea Pigs; Hypersensitivity, Delayed; Male; Mice; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Inbred Strains | 1982 |
Nonsteroidal antiinflammatory agents. 14. Synthesis and pharmacological profile of 6-chloro-5-(cyclopentylmethyl)indan-1-carboxylic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Edema; Indans; Indenes; Male; Rats; Rats, Inbred Strains | 1984 |
Effect of structural change on acute toxicity and antiinflammatory activity in a series of imidazothiazoles and thiazolobenzimidazoles.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chemical Phenomena; Chemistry; Imidazoles; Lethal Dose 50; Locomotion; Male; Mice; Muscle Tonus; Nervous System; Orientation; Rats; Structure-Activity Relationship; Thiazoles | 1981 |
Synthesis and antiinflammatory activity of certain 5,6,7,8-tetrahydroquinolines and related compounds.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Female; Male; Quinolines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar | 1995 |
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Carrageenan; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hyperalgesia; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Membrane Proteins; Molecular Structure; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides | 1997 |
1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Gastrointestinal Diseases; Humans; Imidazoles; Isoenzymes; Membrane Proteins; Mice; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Rats; Structure-Activity Relationship; Sulfonamides; Sulfones | 1997 |
Synthesis and biological evaluation of 3,4-diaryloxazolones: A new class of orally active cyclooxygenase-2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase Inhibitors; Fever; Humans; Magnetic Resonance Spectroscopy; Male; Oxazoles; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Structure-Activity Relationship | 2000 |
Selective cyclooxygenase-2 inhibitors: heteroaryl modified 1,2-diarylimidazoles are potent, orally active antiinflammatory agents.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dogs; Edema; Gastrointestinal Hemorrhage; Humans; Hyperalgesia; Imidazoles; Intestines; Isoenzymes; Membrane Proteins; Mice; Nitriles; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Stomach; Structure-Activity Relationship; Sulfonamides | 2000 |
Synthesis and biological evaluation of quinoline salicylic acids as P-selectin antagonists.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Biological Availability; Cytochrome P-450 Enzyme Inhibitors; Databases, Factual; Edema; Humans; Hydroxyquinolines; In Vitro Techniques; Leukocyte Rolling; Male; P-Selectin; Quinolines; Rats; Rats, Sprague-Dawley; Salicylates; Structure-Activity Relationship | 2007 |
Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoates; Biological Availability; Bronchoconstriction; Calorimetry; Carrageenan; Cell Line; Cyclooxygenase 2 Inhibitors; Edema; Group IV Phospholipases A2; Humans; In Vitro Techniques; Isoenzymes; Male; Mice; Protein Binding; Rats; Rats, Sprague-Dawley; Sheep; Structure-Activity Relationship; Sulfonamides | 2008 |
Synthesis, antinociceptive and anti-inflammatory effects of porphyrins.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Disease Models, Animal; Edema; Erythrocytes; Hemolysis; Indomethacin; Male; Mice; Naproxen; Nociception; Pain; Pain Measurement; Porphyrins; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 2015 |
Discovery of the First Selective IDO2 Inhibitor As Novel Immunotherapeutic Avenues for Rheumatoid Arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Rats | 2022 |
Comparison of individual and combination treatments with naproxen, prednisolone and hydroxychloroquine to treat Complete Freund's Adjuvant induced arthritis.
Topics: Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Experimental; Erythrocytes; Female; Freund's Adjuvant; Humans; Hydroxychloroquine; Inflammation; Male; Naproxen; Oxidative Stress; Prednisolone; Rats; Rats, Wistar | 2021 |
Modeling Combined Immunosuppressive and Anti-inflammatory Effects of Dexamethasone and Naproxen in Rats Predicts the Steroid-Sparing Potential of Naproxen.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Immunosuppressive Agents; Male; Models, Biological; Naproxen; Rats, Inbred Lew; Sex Characteristics; T-Lymphocytes | 2017 |
Structural efficacy of NSAIDs, COX-2 inhibitor and glucocorticoid compared with TNFα blocker: a study in adjuvant-induced arthritis rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Experimental; Celecoxib; Cyclooxygenase 2 Inhibitors; Etanercept; Glucocorticoids; Hindlimb; Methotrexate; Naproxen; Prednisone; Rats; Treatment Outcome; Tumor Necrosis Factor-alpha | 2019 |
Combining naproxen and a dual amylin and calcitonin receptor agonist improves pain and structural outcomes in the collagen-induced arthritis rat model.
Topics: Amylin Receptor Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Bone Density Conservation Agents; Calcitonin; Collagen Type II; Disease Models, Animal; Female; Humans; Islet Amyloid Polypeptide; Naproxen; Pain; Pain Measurement; Rats, Inbred Lew; Receptors, Calcitonin; Swine | 2019 |
Hydrogen sulfide releasing naproxen offers better anti-inflammatory and chondroprotective effect relative to naproxen in a rat model of zymosan induced arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Hydrogen Sulfide; Injections, Intra-Articular; Male; Naproxen; Neutrophils; Pain; Rats; Rats, Wistar; Zymosan | 2015 |
Herb-drug interaction of Andrographis paniculata (Nees) extract and andrographolide on pharmacokinetic and pharmacodynamic of naproxen in rats.
Topics: Administration, Oral; Andrographis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arthritis, Experimental; Chromatography, High Pressure Liquid; Diterpenes; Edema; Female; Freund's Adjuvant; Half-Life; Herb-Drug Interactions; Hyperalgesia; Metabolic Clearance Rate; Naproxen; Nociception; Nociceptive Pain; Pain Threshold; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar | 2017 |
Effect of Disease-Related Changes in Plasma Albumin on the Pharmacokinetics of Naproxen in Male and Female Arthritic Rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Female; Male; Models, Biological; Naproxen; Protein Binding; Rats, Inbred Lew; Serum Albumin; Sex Characteristics | 2017 |
Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Disease Progression; Female; Injections, Intraperitoneal; Male; Models, Biological; Naproxen; Protein Binding; Rats, Inbred Lew; Serum Albumin; Severity of Illness Index; Sex Characteristics | 2017 |
A lipid extract of Perna canaliculus affects the expression of pro-inflammatory cytokines in a rat adjuvant-induced arthritis model.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cell Extracts; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-1alpha; Interleukin-6; Leukotriene Antagonists; Lipids; Lipopolysaccharides; Lymphocyte Activation; Male; Naproxen; Perna; Rats; Rats, Sprague-Dawley; Spleen; Tumor Necrosis Factor-alpha | 2008 |
Can L(+)-lactate be used as a marker of experimentally induced inflammation in rats?
Topics: Animals; Arthritis, Experimental; Biomarkers; Carrageenan; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Freund's Adjuvant; Joints; Lactic Acid; Lactones; Male; Naproxen; Rats; Rats, Sprague-Dawley; Sulfones | 2010 |
Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Blood Pressure; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Gastric Mucosa; Hydrogen Sulfide; Hypertension; Intestinal Mucosa; Intestine, Small; Male; Mice; Molecular Structure; Naproxen; Rats; Rats, Wistar; Stomach Ulcer | 2010 |
Effects of antiinflammatory drugs on arthritic cartilage: a high-frequency quantitative ultrasound study in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cartilage, Articular; Dexamethasone; Disease Models, Animal; Male; Naproxen; Rats; Rats, Wistar; Ultrasonography | 2003 |
Nitric oxide (NO)-releasing naproxen (HCT-3012 [(S)-6-methoxy-alpha-methyl-2-naphthaleneacetic Acid 4-(nitrooxy)butyl ester]) interactions with aspirin in gastric mucosa of arthritic rats reveal a role for aspirin-triggered lipoxin, prostaglandins, and NO
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Eicosanoids; Freund's Adjuvant; Gastric Mucosa; Isoenzymes; Lipoxins; Male; Membrane Proteins; Naproxen; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; Stomach Ulcer; Sulfonamides | 2004 |
Effect of etodolac on articular and bone pathology associated with adjuvant arthritis in rats: a comparison with aspirin and naproxen.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Aspirin; Bone and Bones; Cartilage, Articular; Drug Evaluation, Preclinical; Etodolac; Male; Naproxen; Rats; Rats, Inbred Lew | 1984 |
Comparative effects of long term treatment with etodolac, naproxen and ibuprofen on articular and bone changes associated with adjuvant arthritis in rats.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Body Weight; Bone and Bones; Cartilage, Articular; Etodolac; Ibuprofen; Naproxen; Radiography; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Possible disease-modifying effects of naproxen in the adjuvant-arthritic rat.
Topics: Animals; Arthritis; Arthritis, Experimental; Concanavalin A; Female; Lymphocyte Activation; Mitogens; Naproxen; Phytohemagglutinins; Rats; T-Lymphocytes | 1984 |
Correlation between ossification and inflammation using a rat experimental model.
Topics: Animals; Arthritis; Arthritis, Experimental; Disease Models, Animal; Indomethacin; Naproxen; Ossification, Heterotopic; Phenylbutazone; Rats; Spine; Spondylitis, Ankylosing | 1983 |
Effect of indomethacin and naproxen on the metabolism of collagen in adjuvant-induced arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Collagen; Hydroxyproline; Indomethacin; Male; Naproxen; Rats | 1981 |
Anti-inflammatory potency and gastrointestinal toxicity of a new compound, nitronaproxen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Digestive System; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Female; Male; Naproxen; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1995 |
The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chronic Disease; Disease Models, Animal; Drug Combinations; Exudates and Transudates; Female; Hydroxyurea; Inflammation; Leukotriene B4; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Naproxen; Prostaglandin-Endoperoxide Synthases; Quinolines; Time Factors; Zymosan | 1996 |
Anti-inflammatory activity of polyphosphazene-based naproxen slow-release systems.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Implants; Edema; Freund's Adjuvant; Male; Naproxen; Organophosphorus Compounds; Polymers; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley | 1996 |
Effects of the combined oral administration of NSAIDs and dextromethorphan on behavioral symptoms indicative of arthritic pain in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Behavior, Animal; Dextromethorphan; Diclofenac; Drug Interactions; Drug Therapy, Combination; Etodolac; Ibuprofen; Injections, Intraperitoneal; Male; Naproxen; Pain; Piroxicam; Rats; Rats, Sprague-Dawley | 1996 |
Intercellular adhesion molecule-1 expression in adjuvant arthritis in rats: inhibition by kappa-opioid agonist but not by NSAID.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Female; Intercellular Adhesion Molecule-1; Naproxen; Narcotics; Pyrroles; Rats; Rats, Inbred Lew; Receptors, Opioid, kappa; Thiophenes | 1998 |
NO-naproxen modulates inflammation, nociception and downregulates T cell response in rat Freund's adjuvant arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Dose-Response Relationship, Drug; Edema; Flow Cytometry; Hindlimb; Inflammation; Interleukin-1; Male; Naproxen; Nitric Oxide; Nociceptors; Pain; Pain Measurement; Rats; Rats, Inbred Lew; Receptors, Interleukin-2; T-Lymphocytes; Thymidine; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
Effects of naproxen on connective tissue changes in the adjuvant arthritic rat.
Topics: Animals; Ankylosis; Arthritis; Arthritis, Experimental; Cartilage; Connective Tissue; Female; Naproxen; Osteoporosis; Prostaglandins; Radiography; Rats | 1979 |
Administration of anti-inflammatory compounds in silastic capsules.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Capsules; Indomethacin; Injections, Subcutaneous; Male; Naproxen; Phenylbutazone; Rats; Silicone Elastomers | 1977 |
Anti-inflammatory activity of BF389, a Di-T-butylphenol, in animal models of arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis, Experimental; Collagen; Diamines; Diclofenac; Dinoprostone; Disease Models, Animal; Female; Interleukin-1; Leukotriene B4; Male; Naproxen; Oxazines; Phenols; Piroxicam; Rats; Rats, Inbred Lew; Thromboxane B2 | 1992 |
Interaction studies of tilomisole, aspirin, and naproxen in acute and chronic inflammation with assessment of gastrointestinal irritancy in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Benzimidazoles; Bone and Bones; Carrageenan; Connective Tissue; Drug Interactions; Edema; Gastrointestinal Diseases; Inflammation; Male; Naproxen; Rats; Rats, Sprague-Dawley | 1992 |
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoquinones; Capillary Permeability; Carrageenan; Diclofenac; Edema; Female; Granuloma; Indomethacin; Male; Mice; Naproxen; Pain; Phenylbutazone; Pleurisy; Rats; Rats, Inbred Strains; Silver Nitrate; Stomach Ulcer; Synovitis | 1991 |
Analgesic and anti-inflammatory activities in rats of alpha-(3,5-di-t-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), and its intestinal damage.
Topics: 4-Butyrolactone; Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capillary Permeability; Edema; Furans; Ibuprofen; Indomethacin; Intestinal Diseases; Lethal Dose 50; Male; Naproxen; Rats; Rats, Inbred Strains | 1986 |