naphthalimides has been researched along with Lung Neoplasms in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, C; Chen, MW; Liu, Y; Qian, X; Ren, T; Tang, YJ; Wang, HS; Wang, MF | 1 |
| Gao, Y; Liu, C; Xing, J | 1 |
| Blecher, C; Franco-Echevarría, E; Gonzalez, B; Lin, HY; Mayr, GW; Rohaly, G; Schröder, D; Tödter, K; Windhorst, S | 1 |
| An, Y; Chen, Z; Liu, Y; Lu, X; Ma, F; Peng, Y; Wu, Y; Yang, J; Zhang, G; Zhong, H; Zhou, Z; Zhu, Y | 1 |
| Li, M; Wang, C; Wang, Y; Xie, S; Zhang, J | 1 |
| Esposito, V; Filosa, R; Fiorito, F; Florio, S; Galeone, A; Giancola, C; Massa, A; Paduano, F; Pagano, B; Peduto, A; Petronzi, C; Trapasso, F; Virgilio, A | 1 |
| Li, Z; Qian, X; Yang, Q | 2 |
| Ebbert, LP; Foley, JF; Gesme, DH; Hatfield, AK; Jett, JR; Krook, JE; Mailliard, JA; Maksymiuk, AW; Schreffler, DD; Su, JQ | 1 |
| Blum, R; Bonomi, P; Chang, AY; Smith, JL; Smith, TJ; Tu, ZN; Wiernik, PH | 1 |
| Benavides, A; Casado, A; Díaz-Rubio, E; Font, A; García-Gómez, R; Martín, M; Pérez-Manga, G; Rosell, R | 1 |
| Abad, A; Barnadas, A; Benavides, A; Carles, J; Martin, M; Ribelles, N; Rosell, R | 1 |
| Berger, MZ; Dimaggio, JJ; Gralla, RJ; Heelan, RT; Kris, MG; Marks, LD; Potanovich, LM | 1 |
| Ayoub, J; Cormier, Y; Eisenhauer, EA; Evans, WK; Laberge, F; Shepherd, FA; Wierzbicki, R | 1 |
| Craig, JB; Hardy, J; Harman, G; Havlin, K; Koeller, J; Kuhn, JG; Melink, TJ; Phillips, J; Saez, R; Weiss, GR | 1 |
5 trial(s) available for naphthalimides and Lung Neoplasms
| Article | Year |
|---|---|
A randomized phase II trial of amonafide or trimetrexate in patients with advanced non-small cell lung cancer. A trial of the North Central Cancer Treatment Group.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Administration Schedule; Female; Humans; Imides; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Naphthalimides; Neoplasm Staging; Organophosphonates; Trimetrexate | 1993 |
Phase II trial of gallium nitrate, amonafide and teniposide in metastatic non-small cell lung cancer. An Eastern Cooperative Oncology Group study (E2588).
Topics: Adenine; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drugs, Investigational; Female; Gallium; Humans; Imides; Infusions, Intravenous; Isoquinolines; Longitudinal Studies; Lung Neoplasms; Male; Middle Aged; Naphthalimides; Organophosphonates; Survival Rate; Teniposide | 1995 |
Phase II study of mitonafide in non-small cell lung cancer (NSCLC).
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cognition; Drug Administration Schedule; Female; Humans; Imides; Infusions, Intravenous; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Naphthalimides | 1996 |
Phase I study of mitonafide in 120 hour continuous infusion in non-small cell lung cancer.
Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Humans; Imides; Infusion Pumps; Isoquinolines; Leukopenia; Lung Neoplasms; Male; Middle Aged; Naphthalimides | 1992 |
Phase I clinical investigation of amonafide.
Topics: Adenine; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Drug Evaluation; Female; Half-Life; Humans; Imides; Isoquinolines; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Naphthalimides; Organophosphonates; Prostatic Neoplasms | 1989 |
10 other study(ies) available for naphthalimides and Lung Neoplasms
| Article | Year |
|---|---|
Triptolide induces apoptosis through the calcium/calmodulin‑dependent protein kinase kinaseβ/AMP‑activated protein kinase signaling pathway in non‑small cell lung cancer cells.
Topics: AMP-Activated Protein Kinases; Apoptosis; Benzimidazoles; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Diterpenes; Epoxy Compounds; Humans; Lung Neoplasms; Naphthalimides; Phenanthrenes; Phosphorylation; Pyrazoles; Pyrimidines; Signal Transduction | 2020 |
UNBS5162 inhibits the proliferation of human A549 non-small-cell lung cancer cells by promoting apoptosis.
Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Humans; Lung Neoplasms; Naphthalimides; Urea | 2018 |
The new InsP3Kinase inhibitor BIP-4 is competitive to InsP3 and blocks proliferation and adhesion of lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Benzoxazoles; Calcium Signaling; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; High-Throughput Screening Assays; Humans; Inositol 1,4,5-Trisphosphate; Lung Neoplasms; Molecular Docking Simulation; Naphthalimides; Phosphotransferases (Alcohol Group Acceptor); Pyrazoles | 2015 |
A Novel Naphthalimide Compound Restores p53 Function in Non-small Cell Lung Cancer by Reorganizing the Bak·Bcl-xl Complex and Triggering Transcriptional Regulation.
Topics: bcl-2 Homologous Antagonist-Killer Protein; bcl-X Protein; Carcinoma, Non-Small-Cell Lung; G1 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Lung Neoplasms; MCF-7 Cells; Multiprotein Complexes; Naphthalimides; Transcription, Genetic; Tumor Suppressor Protein p53 | 2016 |
Synthesis and evaluation of novel amonafide-polyamine conjugates as anticancer agents.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Microscopy, Fluorescence; Naphthalimides; Neoplasms; Organophosphonates; Polyamines; Transplantation, Heterologous | 2017 |
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands.
Topics: Animals; Calorimetry; Cell Line, Tumor; Cell Proliferation; Circular Dichroism; Enzyme Inhibitors; G-Quadruplexes; Humans; Ligands; Lung Neoplasms; Magnetic Resonance Spectroscopy; Melanoma; Mice; Molecular Structure; Naphthalimides; NIH 3T3 Cells; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Telomerase | 2011 |
Novel thiazonaphthalimides as efficient antitumor and DNA photocleaving agents: effects of intercalation, side chains, and substituent groups.
Topics: Adenine; Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; DNA; DNA, Superhelical; Drug Screening Assays, Antitumor; Humans; Imides; Intercalating Agents; Isoquinolines; Leukemia P388; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Naphthalenes; Naphthalimides; Organophosphonates; Phthalimides; Structure-Activity Relationship; Thiadiazines; Ultraviolet Rays | 2005 |
Highly efficient antitumor agents of heterocycles containing sulfur atom: linear and angular thiazonaphthalimides against human lung cancer cell in vitro.
Topics: Antineoplastic Agents; Cell Line, Tumor; Heterocyclic Compounds; Humans; Lung Neoplasms; Naphthalimides; Structure-Activity Relationship; Sulfur Compounds | 2007 |
Phase II trial of amonafide in patients with stage III and IV non-small-cell lung cancer.
Topics: Adenine; Adenocarcinoma; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Drug Tolerance; Female; Humans; Imides; Intercalating Agents; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Naphthalimides; Neoplasm Staging; Organophosphonates; Remission Induction | 1991 |
Phase II study of amonafide: results of treatment and lessons learned from the study of an investigational agent in previously untreated patients with extensive small-cell lung cancer.
Topics: Adenine; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Clinical Protocols; Drug Evaluation; Drugs, Investigational; Female; Humans; Imides; Infusions, Intravenous; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Naphthalimides; Organophosphonates | 1990 |