Page last updated: 2024-08-24

naphthalimides and Liver Neoplasms

naphthalimides has been researched along with Liver Neoplasms in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's14 (82.35)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Cao, Y; Che, D; Dai, F; Fan, R; Feng, Y; Gao, L; Gao, M; Ge, C; Li, J; Wang, C; Wang, S; Wang, Y; Xie, S; Xu, X1
Chen, Y; Jia, H; Li, L; Li, Y; Ma, J; Ma, R; Ma, Y; Su, S; Wang, C; Wang, J; Xie, S; Yu, L; Yue, K; Zhang, P; Zhang, Z1
Appella, D; Avram, MJ; Chen, Z; Green, R; Gupta, P; Huang, M; Huang, S; Kandela, I; Liu, Y; Lou, G; Mazar, A; Norton, JT; Shank, NI; Tang, S; Wang, C1
Duan, Q; Jia, P; Li, Z; Liu, C; Sheng, W; Wang, Z; Zhang, X; Zhu, B; Zhu, H; Zhuang, Z1
Choy, T; Green, RM; Huang, S; Kim, DH; Larson, AC; Omary, RA1
Deng, J; Li, Y; Luo, Q; Zhang, Z1
Chen, GR; He, XP; James, TD; Li, J; Shi, DT; Tian, H; Zang, Y; Zhou, D1
Chen, J; Kim, DH; Larson, AC; Omary, RA1
Deng, JJ; Li, Y; Luo, QY; Zhang, ZZ1
Lai, Y; Li, Y; Luo, Q; Zhang, Z1
Carr, BI; Kar, S; Wang, M; Wang, Z1
Li, Q; Mei, ZH; Wang, CJ; Wang, JH; Xie, SQ; Zhang, YH; Zhao, J1
Alcala, MA; Bartlett, DL; Kwan, SY; Lang, M; Lee, YJ; Petoud, S; Shade, CM; Uh, H; Wang, M; Weber, SG1
Carazo, A; León, J; Martín-Álvarez, AB; Muñoz-Gámez, JA; Oliver, FJ; Quiles-Pérez, R; Ruiz-Extremera, A; Salmerón, J; Sanjuan-Nuñez, L1
Li, Q; Miao, JW; Wang, CJ; Xie, SQ; Xu, FH; Zhang, YH; Zhao, J1
Li, Q; Li, Z; Wang, CJ; Xie, SQ; Zhang, YH; Zhao, J1
Li, M; Li, Q; Ma, HX; Tian, ZY; Wang, CJ; Xie, SQ; Zhang, YH; Zhao, J1

Other Studies

17 other study(ies) available for naphthalimides and Liver Neoplasms

ArticleYear
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
    International journal of molecular sciences, 2021, Oct-12, Volume: 22, Issue:20

    Topics: Acetylcysteine; Adenine; Antioxidants; Autophagic Cell Death; Autophagosomes; Carcinoma, Hepatocellular; DNA Damage; Hep G2 Cells; Humans; Liver Neoplasms; Lysosomes; Microtubule-Associated Proteins; Mitochondria; Naphthalimides; Proteome; Proteomics; Reactive Oxygen Species; Sequestosome-1 Protein

2021
A naphthalimide-polyamine conjugate preferentially accumulates in hepatic carcinoma metastases as a lysosome-targeted antimetastatic agent.
    European journal of medicinal chemistry, 2021, Oct-05, Volume: 221

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Lysosomes; Molecular Structure; Naphthalimides; Polyamines; Structure-Activity Relationship

2021
6-Methoxyethylamino-numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017, Volume: 31, Issue:12

    Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Apoptosis; Aspartate Aminotransferases; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Hep G2 Cells; Humans; Liver Neoplasms; Male; Mice; Naphthalimides; Niacinamide; Phenylurea Compounds; Sorafenib; Xenograft Model Antitumor Assays

2017
Rational Design of a Hepatoma-Specific Fluorescent Probe for HOCl and Its Bioimaging Applications in Living HepG2 Cells.
    Analytical chemistry, 2019, 02-05, Volume: 91, Issue:3

    Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Fluorescent Dyes; Hep G2 Cells; Humans; Hypochlorous Acid; Liver Neoplasms; Molecular Structure; Naphthalimides; Optical Imaging; Reactive Oxygen Species

2019
Microfluidic fabrication of 6-methoxyethylamino numonafide-eluting magnetic microspheres.
    Acta biomaterialia, 2014, Volume: 10, Issue:2

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dextrans; Humans; Liver Neoplasms; Magnetic Phenomena; Magnetic Resonance Spectroscopy; Magnetite Nanoparticles; Microfluidics; Microspheres; Naphthalimides; Particle Size

2014
PARP-1 inhibitor sensitizes arsenic trioxide in hepatocellular carcinoma cells via abrogation of G2/M checkpoint and suppression of DNA damage repair.
    Chemico-biological interactions, 2015, Jan-25, Volume: 226

    Topics: 1-Naphthylamine; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cyclin B1; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Liver Neoplasms; M Phase Cell Cycle Checkpoints; Naphthalimides; Oxides; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Quinolones; Up-Regulation

2015
Selective fluorogenic imaging of hepatocellular H2S by a galactosyl azidonaphthalimide probe.
    Chemical communications (Cambridge, England), 2015, Feb-28, Volume: 51, Issue:17

    Topics: Azides; Carcinoma, Hepatocellular; Cell Line, Tumor; Fluorescent Dyes; Galactose; HCT116 Cells; HeLa Cells; Hep G2 Cells; Humans; Hydrogen Sulfide; Liver Neoplasms; Molecular Imaging; Molecular Structure; Naphthalimides

2015
MRI visible drug eluting magnetic microspheres for transcatheter intra-arterial delivery to liver tumors.
    Theranostics, 2015, Volume: 5, Issue:5

    Topics: Adenine; Alginates; Animals; Antineoplastic Agents; Disease Models, Animal; Drug Carriers; Glucuronic Acid; Hexuronic Acids; Injections, Intra-Arterial; Liver Neoplasms; Magnetic Resonance Imaging; Microspheres; Naphthalimides; Organophosphonates; Rats

2015
[4-amino-1,8-naphthalimide on the Sensitive effect of arsenic trioxide in hepatocellular carcinoma cells].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2015, Volume: 46, Issue:2

    Topics: 1-Naphthylamine; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Survival; DNA Damage; DNA Repair; Hep G2 Cells; Humans; Liver Neoplasms; Naphthalimides; Oxides; Quinolones

2015
The role of NF-κB in PARP-inhibitor-mediated sensitization and detoxification of arsenic trioxide in hepatocellular carcinoma cells.
    The Journal of toxicological sciences, 2015, Volume: 40, Issue:3

    Topics: 1-Naphthylamine; Acetylcysteine; Antineoplastic Agents; Antioxidants; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; DNA Damage; Hep G2 Cells; Humans; Inactivation, Metabolic; Liver Neoplasms; Naphthalimides; NF-kappa B; Oxidative Stress; Oxides; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolones; Reactive Oxygen Species

2015
Involvement of ATM-mediated Chk1/2 and JNK kinase signaling activation in HKH40A-induced cell growth inhibition.
    Journal of cellular physiology, 2009, Volume: 221, Issue:1

    Topics: Acridones; Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA; DNA-Binding Proteins; Enzyme Activation; Histones; Humans; Liver Neoplasms; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Naphthalimides; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Inbred F344; Tumor Suppressor Proteins

2009
NPC-16, a novel naphthalimide-polyamine conjugate, induced apoptosis and autophagy in human hepatoma HepG2 cells and Bel-7402 cells.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:1

    Topics: Acridine Orange; Annexin A5; Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Naphthalimides; Necrosis; Polyamines; Receptors, Death Domain; Signal Transduction

2011
Luminescence targeting and imaging using a nanoscale generation 3 dendrimer in an in vivo colorectal metastatic rat model.
    Nanomedicine : nanotechnology, biology, and medicine, 2011, Volume: 7, Issue:3

    Topics: 1-Naphthylamine; Animals; Catheterization; Cell Line, Tumor; Colorectal Neoplasms; Dendrimers; Diagnostic Imaging; Disease Models, Animal; Europium; Liver; Liver Neoplasms; Luminescence; Nanoparticles; Naphthalimides; Particle Size; Quinolones; Rats; Time Factors

2011
Inhibition of poly (ADP-ribose) polymerase-1 enhances doxorubicin activity against liver cancer cells.
    Cancer letters, 2011, Feb-01, Volume: 301, Issue:1

    Topics: 1-Naphthylamine; Antibiotics, Antineoplastic; Apoptosis; bcl-X Protein; Cell Line, Tumor; Cell Survival; DNA Repair; Doxorubicin; Drug Synergism; Enzyme Inhibitors; ErbB Receptors; Humans; Liver Neoplasms; Naphthalimides; Poly(ADP-ribose) Polymerase Inhibitors; Quinolones

2011
3-Nitro-naphthalimide and nitrogen mustard conjugate NNM-25 induces hepatocellular carcinoma apoptosis via PARP-1/p53 pathway.
    Apoptosis : an international journal on programmed cell death, 2012, Volume: 17, Issue:7

    Topics: Animals; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA, Neoplasm; Fluorescence; Humans; Intercalating Agents; Liver Neoplasms; Male; Membrane Potential, Mitochondrial; Mice; Naphthalimides; Neoplasm Proteins; Nitrogen Mustard Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; RNA, Small Interfering; Signal Transduction; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2012
BND-12, a novel nonhaematotoxic naphthalimide derivative, inhibits tumour growth and metastasis of hepatocellular carcinoma.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:10

    Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Male; Mice; Mitochondria; Naphthalimides; Neoplasm Metastasis; Organophosphonates; Survival Rate; Toxicity Tests; Xenograft Model Antitumor Assays

2012
Antitumor effects and preliminary systemic toxicity of ANISpm in vivo and in vitro.
    Anti-cancer drugs, 2013, Volume: 24, Issue:1

    Topics: Animals; Apoptosis; bcl-Associated Death Protein; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatocytes; Humans; Liver Neoplasms; Male; Mice; Naphthalimides; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Spermine; TOR Serine-Threonine Kinases; Toxicity Tests

2013