naphthalimides has been researched along with Colorectal Neoplasms in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, F; Feng, Y; Gao, L; Ge, C; Wang, C; Wang, S; Wang, Y; Xie, S; Xu, X; Zhang, K; Zhang, Z; Zhao, Y | 1 |
| Blagojevic, B; Cheng, X; Dabiri, Y; Ott, I; Schmid, A; Streciwilk, W; Theobald, J; Wölfl, S | 1 |
| Cheng, Z; Li, Q; Liang, X; Liu, J; Qian, X; Wang, Z; Xu, Y; Yin, P; Zhu, H | 1 |
| Alcala, MA; Bartlett, DL; Kwan, SY; Lang, M; Lee, YJ; Petoud, S; Shade, CM; Uh, H; Wang, M; Weber, SG | 1 |
| Li, JH; Li, Q; Wang, CJ; Wang, JH; Xie, SQ; Zhang, YH; Zhao, J | 1 |
| Burch, PA; Kovach, JS; Marschke, RF; O'Connell, MJ; Rubin, J; Schutt, AJ; Wieand, HS | 1 |
| Brown, TD; Craig, JB; Einstein, AB; Fleming, T; Goodman, PJ; Macdonald, JS | 1 |
| Abad, A; Benavides, A; Díaz-Puente, MT; Fabregat, X; Font, A; Grávalos, C; Martín, M; Molina, F | 1 |
| Comis, RL; Hudes, GR; O'Dwyer, PJ; Ozols, RF; Paul, AR; Walczak, J | 1 |
| Depisch, D; Haider, K; Kornek, G; Scheithauer, W | 1 |
4 trial(s) available for naphthalimides and Colorectal Neoplasms
| Article | Year |
|---|---|
Advanced colorectal adenocarcinoma: treatment with amonafide.
Topics: Adenine; Antineoplastic Agents; Carcinoma; Colorectal Neoplasms; Humans; Imides; Intercalating Agents; Isoquinolines; Naphthalimides; Organophosphonates | 1994 |
Phase II trial of amonafide in advanced colorectal cancer: a SouthWest Oncology Group study.
Topics: Adenine; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colorectal Neoplasms; Female; Humans; Imides; Isoquinolines; Male; Middle Aged; Naphthalimides; Organophosphonates | 1993 |
Phase II study of Mitonafide in advanced and relapsed colorectal cancer.
Topics: Aged; Antineoplastic Agents; Colorectal Neoplasms; Female; Humans; Imides; Isoquinolines; Male; Middle Aged; Naphthalimides | 1996 |
Phase II study of amonafide (nafidamide, NSC 308847) in advanced colorectal cancer.
Topics: Adenine; Adenocarcinoma; Antineoplastic Agents; Colorectal Neoplasms; Drug Evaluation; Humans; Imides; Isoquinolines; Middle Aged; Naphthalimides; Organophosphonates | 1991 |
6 other study(ies) available for naphthalimides and Colorectal Neoplasms
| Article | Year |
|---|---|
Suppression of oxidative phosphorylation and IDH2 sensitizes colorectal cancer to a naphthalimide derivative and mitoxantrone.
Topics: Animals; Antioxidants; Autophagy; Cell Death; Cell Line, Tumor; Citric Acid Cycle; Colorectal Neoplasms; Down-Regulation; HCT116 Cells; HT29 Cells; Humans; Isocitrate Dehydrogenase; Mice; Mice, Inbred BALB C; Mitochondria; Mitoxantrone; Naphthalimides; Oxidative Phosphorylation; Oxidative Stress; Reactive Oxygen Species | 2021 |
A Ruthenium(II) N-Heterocyclic Carbene (NHC) Complex with Naphthalimide Ligand Triggers Apoptosis in Colorectal Cancer Cells via Activating the ROS-p38 MAPK Pathway.
Topics: Apoptosis; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Heterocyclic Compounds; Humans; Ligands; Membrane Potential, Mitochondrial; Methane; Mitochondria; Naphthalimides; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Ruthenium; Signal Transduction | 2018 |
Induction of apoptosis and suppression of ERCC1 expression by the potent amonafide analogue 8-c in human colorectal carcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Shape; Colorectal Neoplasms; Comet Assay; DNA Damage; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Endonucleases; Gene Expression Regulation, Neoplastic; Humans; Naphthalimides; Neoplasm Proteins; RNA Interference; RNA, Small Interfering; Single-Cell Analysis | 2013 |
Luminescence targeting and imaging using a nanoscale generation 3 dendrimer in an in vivo colorectal metastatic rat model.
Topics: 1-Naphthylamine; Animals; Catheterization; Cell Line, Tumor; Colorectal Neoplasms; Dendrimers; Diagnostic Imaging; Disease Models, Animal; Europium; Liver; Liver Neoplasms; Luminescence; Nanoparticles; Naphthalimides; Particle Size; Quinolones; Rats; Time Factors | 2011 |
COX-2-independent induction of apoptosis by celecoxib and polyamine naphthalimide conjugate mediated by polyamine depression in colorectal cancer cell lines.
Topics: Acetyltransferases; Amino Acid Chloromethyl Ketones; Apoptosis; Caspases; Celecoxib; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Cytochromes c; Drug Synergism; Enzyme Activation; Humans; Membrane Potential, Mitochondrial; Naphthalimides; Polyamines; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Sulfonamides; Up-Regulation | 2012 |
Amonafide in metastatic colorectal carcinoma.
Topics: Adenine; Aged; Antineoplastic Agents; Colorectal Neoplasms; Female; Humans; Imides; Isoquinolines; Male; Middle Aged; Naphthalimides; Neoplasm Metastasis; Organophosphonates | 1990 |