Compounds > naphthalimides
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naphthalimides and Colonic Neoplasms

naphthalimides has been researched along with Colonic Neoplasms in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ji, L; Li, S; Liu, S; Liu, Z; Meng, X; Tang, S; Yang, S; Yu, S1
Liu, JM; Lv, HZ; Wang, CC; Ye, XY; Zhang, F1
Antonini, I; Cristalli, G; Dal Ben, D; Lambertucci, C; Volpini, R1
Bifulco, G; Capranico, G; Caprariis, Pd; Festa, M; Filosa, R; Micco, SD; Peduto, A; Petrella, A1
Bestwick, CS; Duthie, SJ; Kong Thoo Lin, P; Milne, L; Ralton, LD1
Alberts, DS; Dorr, RT; Remers, WA; Sami, SM; Sólyom, AM1

Other Studies

6 other study(ies) available for naphthalimides and Colonic Neoplasms

ArticleYear
A novel triazolonaphthalimide induces apoptosis and inhibits tumor growth by targeting DNA and DNA-associated processes.
    Oncotarget, 2017, Jun-06, Volume: 8, Issue:23

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Colonic Neoplasms; DNA; DNA Replication; DNA Topoisomerases, Type II; HCT116 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthalimides; Sarcoma; Triazoles; Xenograft Model Antitumor Assays

2017
UNBS5162 inhibits colon cancer growth via suppression of PI3K/Akt signaling pathway.
    Medecine sciences : M/S, 2018, Volume: 34 Focus issue F1

    Topics: Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Colonic Neoplasms; Down-Regulation; HCT116 Cells; Humans; Naphthalimides; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Urea

2018
Design, synthesis, and biological evaluation of new mitonafide derivatives as potential antitumor drugs.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Antineoplastic Agents; Aza Compounds; Colonic Neoplasms; DNA; Drug Design; HT29 Cells; Humans; Inhibitory Concentration 50; Intercalating Agents; Isoquinolines; Naphthalimides; Structure-Activity Relationship; Tumor Cells, Cultured

2008
Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors.
    Bioorganic & medicinal chemistry, 2009, Jan-01, Volume: 17, Issue:1

    Topics: Cell Line, Tumor; Colonic Neoplasms; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Models, Molecular; Naphthalimides; Structure-Activity Relationship; Topoisomerase II Inhibitors

2009
The influence of bisnaphthalimidopropyl polyamines on DNA instability and repair in Caco-2 colon epithelial cells.
    Cell biology and toxicology, 2011, Volume: 27, Issue:6

    Topics: Adenocarcinoma; Apoptosis; Caco-2 Cells; Cell Survival; Colonic Neoplasms; Comet Assay; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Intercalating Agents; Naphthalimides; Oxidation-Reduction; Quinolones; Spermine

2011
Amino-substituted 2-[2'-(dimethylamino)ethyl]-1,2-dihydro-3H- dibenz[de,h]isoquinoline-1,3-diones. Synthesis, antitumor activity, and quantitative structure--activity relationship.
    Journal of medicinal chemistry, 1995, Mar-17, Volume: 38, Issue:6

    Topics: Adenine; Animals; Antineoplastic Agents; Cattle; Colonic Neoplasms; DNA; Doxorubicin; Heart Diseases; Humans; Imides; Isoquinolines; Leukemia P388; Male; Mice; Mice, Inbred DBA; Mitoxantrone; Naphthalimides; Organophosphonates; Structure-Activity Relationship; Tumor Cells, Cultured

1995