Page last updated: 2024-08-24

naphthalimides and Benign Neoplasms

naphthalimides has been researched along with Benign Neoplasms in 47 studies

Research

Studies (47)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (10.64)	18.2507
2000's	5 (10.64)	29.6817
2010's	24 (51.06)	24.3611
2020's	13 (27.66)	2.80

Authors

Authors	Studies
Efendiev, KT; Fedorova, OA; Mironov, AF; Morozova, NB; Panchenko, PA; Pankratov, AA; Pavlova, MA; Plyutinskaya, AD; Pritmov, DA; Semkina, AS	1
Cangiotti, M; Canonico, B; Ciacci, C; Fusi, V; Giorgi, L; Grabchev, I; Montanari, M; Ottaviani, MF; Papa, S; Staneva, D	1
Gao, F; Hu, X; Sun, J; Zhang, Q; Zhang, Z	1
Luxami, V; Paul, K; Tandon, N; Tandon, R	1
Dong, L; Fang, H; Guo, Z; Han, Z; Shi, X; Wang, X; Wang, Y; Yuan, H; Zhu, Z	1
Biniek-Antosiak, K; Denel-Bobrowska, M; Fedoruk-Wyszomirska, A; Gurda-Woźna, D; Kowalczyk, A; Olejniczak, AB; Orlicka-Płocka, M; Rykowski, S; Rypniewski, W; Stączek, P; Wyszko, E	1
Chen, X; Liu, Z; Ma, W; Tian, Z; Xia, X; Xu, Z; Zhang, S; Zhang, Y	1
Lin, W; Peng, M; Yin, J	1
Guo, Y; Guo, Z; He, Y; Song, D; Wang, X; Wu, S; Zhang, S; Zhu, Z	1
Jia, P; Li, Z; Liang, C; Liu, C; Sheng, W; Yu, Y; Zhang, H; Zhang, X; Zhu, B; Zhu, H	1
Luxami, V; Paul, K; Singh, I	1
Akkoç, S; Coban, B; Cömert, F; Kandemir, I; Yildiz, U	1
Bano, G; Dhanalakshmi, P; Jena, S; Thilagar, P	1
Huang, RZ; Jiang, H; Liang, GB; Qin, JT; Wang, HL; Wang, HS; Wei, JH; Zhang, Y	1
Nguyen, VN; Yan, Y; Yoon, J; Zhao, J	1
Finney, N; Wang, Y; Wu, H; Yang, L; Zhang, Y	1
Cao, ZR; Du, SY; He, X; Li, XL; Qi, YM; Rong, RX; Wang, KR; Wang, SS	1
Kaur, H; Luxami, V; Paul, K; Tandon, N; Tandon, R	1
Bernardos, A; Chaib, S; Galiana, I; Garrido, E; Lozano-Torres, B; Martínez-Máñez, R; Muñoz-Espín, D; Rovira, M; Sancenón, F; Serrano, M	1
Fan, YR; Huang, M; Huang, Y; Song, Y; Tian, DN; Wu, CX; Yang, XB	1
Chen, GR; He, XP; James, TD; Li, J; Liu, Y; Ma, X; Wang, H; Wang, X; Xu, C; Zang, Y	1
Bandow, JE; Cheng, X; Dabiri, Y; Hager, L; Keppler, BK; Ott, I; Prochnow, P; Streciwilk, W; Terenzi, A; Wölfl, S	1
Tomczyk, MD; Walczak, KZ	1
Coles, SJ; Groves, LM; Hayes, AJ; Horton, PN; Isaacs, MD; Lloyd, D; Pope, SJA; Symonds, NO; Ward, BD; Williams, CF	1
Kumari, R; Ningthoujam, RS; Sunil, D	1
Fujikawa, Y; Inoue, H; Mori, M; Nampo, T; Terakado, K	1
Chen, Z; Han, L; Qian, X; Xu, M; Xu, Y	1
Fedorov, YV; Fedorova, OA; Grin, MA; Jonusauskas, G; Mironov, AF; Panchenko, PA; Reshetnikov, RI; Schelkunova, AE; Sergeeva, AN	1
Acharya, JK; Kosakowska-Cholody, T; Lin, J; Scheffer, L; Srideshikan, SM; Tarasova, NI	1
Baral, R; Goswami, KK; Mallick, A; Sanyal, U; Saxena, AK; Sen, A	1
Fu, C; Huang, C; Jia, N; Jia, T; Yang, H	1
Ganesan, S; Karunakaran, SC; Nair, AS; Priya, S; Ramaiah, D; Saneesh Babu, PS; Tyagi, N; Varughese, S; Viji, M	1
Li, M; Wang, C; Wang, Y; Xie, S; Zhang, J	1
Cho, SH; James, TD; Jang, JH; Kang, C; Kim, JS; Kim, WR; Sharma, A	1
Ingrassia, L; Kiss, R; Lefranc, F; Mijatovic, T	1
Lv, M; Xu, H	1
Azeeza, S; Bharathi, EV; Kamal, A; Malik, MS; Shetti, RV	1
Bhuniya, S; Han, JH; Kang, C; Kim, JS; Kim, JY; Lee, MH; Sessler, JL	1
Horton, JK; Wilson, SH	1
Favaudon, V; Fernet, M; Giocanti, N; Godon, C; Mégnin-Chanet, F; Noël, G	1
Li, Y; Liu, J; Qian, X; Xu, Y; Yin, H	1
Benavides, A; Casado, A; Díaz-Rubio, E; López-Vega, JM; Martín, M	1
Berezin, F; Janisch, L; Lane, LB; Mick, R; Ratain, MJ; Schilsky, RL; Vogelzang, NJ	1
Akerman, S; Allen, SL; Budman, DR; Calabro, A; Chan, K; Fusco, D; Hock, K; Kreis, W; Mittelman, A; Puccio, C; Spigelman, M	1
Alberts, DS; Dorr, RT; Hersh, EM; Liddil, JD; Remers, W; Sami, SM	1
Benavides, A; Fernández-Martos, C; Forner, E; Gaspar, C; Llombart, M; Muñoz, M; Olmos, T; Poveda, A; Ruiz, A; Soriano, V	1
Diasio, RB; Stagg, MP	1

Reviews

9 review(s) available for naphthalimides and Benign Neoplasms

Article	Year
Recent developments on 1,8-Naphthalimide moiety as potential target for anticancer agents. Bioorganic chemistry, 2022, Volume: 121 Topics: Antineoplastic Agents; Cell Line, Tumor; DNA; Humans; Naphthalimides; Neoplasms; Structure-Activity Relationship	2022
1,8-Naphthalimide: A Potent DNA Intercalator and Target for Cancer Therapy. Chemical record (New York, N.Y.), 2017, Volume: 17, Issue:10 Topics: Animals; Antineoplastic Agents; Coordination Complexes; DNA; Drug Discovery; Humans; Intercalating Agents; Models, Molecular; Naphthalimides; Neoplasms	2017
l,8-Naphthalimide based DNA intercalators and anticancer agents. A systematic review from 2007 to 2017. European journal of medicinal chemistry, 2018, Nov-05, Volume: 159 Topics: Antineoplastic Agents; Cell Proliferation; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Neoplasm; Humans; Intercalating Agents; Naphthalimides; Neoplasms; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2018
Naphthalimides in fluorescent imaging of tumor hypoxia - An up-to-date review. Bioorganic chemistry, 2019, Volume: 88 Topics: Animals; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Microscopy, Fluorescence; Molecular Structure; Naphthalimides; Neoplasms; Optical Imaging; Structure-Activity Relationship; Tumor Hypoxia	2019
Rationally designed multitarget anticancer agents. Current medicinal chemistry, 2013, Volume: 20, Issue:13 Topics: Animals; Antineoplastic Agents; Drug Design; Humans; Molecular Targeted Therapy; Naphthalimides; Neoplasms; Quinazolines	2013
Naphthalimides and azonafides as promising anti-cancer agents. Current medicinal chemistry, 2009, Volume: 16, Issue:10 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Humans; Inhibitory Concentration 50; Molecular Structure; Naphthalimides; Neoplasms; Structure-Activity Relationship	2009
Overview of naphthalimide analogs as anticancer agents. Current medicinal chemistry, 2009, Volume: 16, Issue:36 Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Naphthalimides; Neoplasms; Structure-Activity Relationship	2009
Search for new and novel chemotherapeutics for the treatment of human malignancies. Mini reviews in medicinal chemistry, 2010, Volume: 10, Issue:5 Topics: Antineoplastic Agents; Benzodiazepines; Benzothiadiazines; Humans; Naphthalimides; Neoplasms; Podophyllotoxin; Pyrimidines; Thiones	2010
Novel chemotherapeutic agents in early clinical development. Current opinion in oncology, 1990, Volume: 2, Issue:6 Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate	1990

Trials

5 trial(s) available for naphthalimides and Benign Neoplasms

Article	Year
Phase I study of mitonafide with a 3-day administration schedule: early interruption due to severe central nervous system toxicity. Investigational new drugs, 1994, Volume: 12, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Central Nervous System Diseases; Drug Administration Schedule; Female; Humans; Imides; Isoquinolines; Male; Middle Aged; Naphthalimides; Neoplasms	1994
Phase I study of amonafide dosing based on acetylator phenotype. Cancer research, 1993, May-15, Volume: 53, Issue:10 Suppl Topics: Acetylation; Adenine; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Humans; Imides; Intercalating Agents; Isoquinolines; Lymphoma; Male; Middle Aged; Models, Biological; Naphthalimides; Neoplasms; Organophosphonates; Phenotype	1993
Clinical pharmacokinetics of amonafide (NSC 308847) in 62 patients. Cancer investigation, 1996, Volume: 14, Issue:4 Topics: Adenine; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Imides; Isoquinolines; Male; Mathematics; Metabolic Clearance Rate; Middle Aged; Models, Biological; Naphthalimides; Neoplasms; Organophosphonates; Polymorphism, Genetic	1996
Phase I study of mitonafide in solid tumors. Investigational new drugs, 1992, Volume: 10, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Humans; Imides; Infusions, Intravenous; Isoquinolines; Male; Memory Disorders; Middle Aged; Naphthalimides; Neoplasms	1992
Novel chemotherapeutic agents in early clinical development. Current opinion in oncology, 1990, Volume: 2, Issue:6 Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate	1990

Other Studies

34 other study(ies) available for naphthalimides and Benign Neoplasms

Article	Year
Photodiagnosis and photodynamic effects of bacteriochlorin-naphthalimide conjugates on tumor cells and mouse model. Journal of photochemistry and photobiology. B, Biology, 2021, Volume: 223 Topics: Animals; Cell Line, Tumor; Lasers; Mice; Naphthalimides; Neoplasms; Optical Imaging; Photochemotherapy; Photosensitizing Agents; Porphyrins; Tissue Distribution; Transplantation, Homologous	2021
Characterization of a fluorescent 1,8-naphthalimide-functionalized PAMAM dendrimer and its Cu(ii) complexes as cytotoxic drugs: EPR and biological studies in myeloid tumor cells. Biological chemistry, 2022, 02-23, Volume: 403, Issue:3 Topics: Antineoplastic Agents; Dendrimers; Electron Spin Resonance Spectroscopy; Humans; Leukocytes, Mononuclear; Naphthalimides; Neoplasms; Polyamines	2022
Dual-Targeting into the Mitochondria of Cancer Cells for Ratiometric Investigation of the Dynamic Fluctuation of Sulfur Dioxide and Formaldehyde with Two-Photon Integrated Semiconducting Polymer Dots. ACS applied materials & interfaces, 2022, Jan-12, Volume: 14, Issue:1 Topics: Animals; Cell Line, Tumor; Fluorenes; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Formaldehyde; Humans; Limit of Detection; Male; Mice; Mitochondria; Naphthalimides; Neoplasms; Photons; Polymers; Quantum Dots; RAW 264.7 Cells; Semiconductors; Sulfur Dioxide; Zebrafish	2022
Platinum-Based Two-Photon Photosensitizer Responsive to NIR Light in Tumor Hypoxia Microenvironment. Journal of medicinal chemistry, 2022, 06-09, Volume: 65, Issue:11 Topics: Animals; Cell Line, Tumor; Hypoxia; Mice; Naphthalimides; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum; Reactive Oxygen Species; Tumor Hypoxia; Tumor Microenvironment	2022
Carboranyl-1,8-naphthalimide intercalators induce lysosomal membrane permeabilization and ferroptosis in cancer cell lines. Journal of enzyme inhibition and medicinal chemistry, 2023, Volume: 38, Issue:1 Topics: Antineoplastic Agents; Cell Line; Cell Line, Tumor; DNA; Ferroptosis; Intercalating Agents; Lysosomes; Naphthalimides; Neoplasms	2023
Potential anticancer agent for selective damage to mitochondria or lysosomes: Naphthalimide-modified fluorescent biomarker half-sandwich iridium (III) and ruthenium (II) complexes. European journal of medicinal chemistry, 2019, Nov-01, Volume: 181 Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Drug Screening Assays, Antitumor; Fluorescent Dyes; Humans; Iridium; Lysosomes; Membrane Potential, Mitochondrial; Mitochondria; Naphthalimides; Neoplasms; Ruthenium	2019
Tracking lysosomal polarity variation in inflamed, obese, and cancer mice guided by a fluorescence sensing strategy. Chemical communications (Cambridge, England), 2019, Sep-21, Volume: 55, Issue:74 Topics: Animals; Cell Polarity; Embryo, Nonmammalian; Female; Fluorescence; Fluorescent Dyes; HeLa Cells; Humans; Inflammation; Lysosomes; Mice, Inbred BALB C; Microscopy, Confocal; Microscopy, Fluorescence; Naphthalimides; Neoplasms; Obesity; Optical Imaging; Photons; Zebrafish	2019
Enhancing Cytotoxicity of a Monofunctional Platinum Complex via a Dual-DNA-Damage Approach. Inorganic chemistry, 2019, Oct-07, Volume: 58, Issue:19 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Crystallography, X-Ray; DNA Damage; Humans; Intercalating Agents; Membrane Potential, Mitochondrial; Mice, Inbred ICR; Models, Molecular; Naphthalimides; Neoplasms; Organoplatinum Compounds; Pyridines	2019
A novel highly sensitive fluorescent probe for bioimaging biothiols and its applications in distinguishing cancer cells from normal cells. The Analyst, 2019, Nov-18, Volume: 144, Issue:23 Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cysteine; Fluorescent Dyes; Glutathione; HeLa Cells; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Limit of Detection; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Naphthalimides; Neoplasms; Optical Imaging; RAW 264.7 Cells; Zebrafish	2019
Synthesis of naphthalimide-phenanthro[9,10-d]imidazole derivatives: In vitro evaluation, binding interaction with DNA and topoisomerase inhibition. Bioorganic chemistry, 2020, Volume: 96 Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; DNA; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Humans; Imidazoles; Molecular Docking Simulation; Naphthalimides; Neoplasms; Phenanthrenes; Structure-Activity Relationship; Topoisomerase II Inhibitors	2020
Synthesis of naphthalimide derivatives with potential anticancer activity, their comparative ds- and G-quadruplex-DNA binding studies and related biological activities. Molecular biology reports, 2020, Volume: 47, Issue:3 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Survival; Circular Dichroism; DNA; Escherichia coli; G-Quadruplexes; Hep G2 Cells; Humans; MCF-7 Cells; Microbial Sensitivity Tests; Models, Chemical; Molecular Structure; Naphthalimides; Neoplasms; Structure-Activity Relationship	2020
Delayed Fluorescence, Room Temperature Phosphorescence, and Mechanofluorochromic Naphthalimides: Differential Imaging of Normoxia and Hypoxia Live Cancer Cells. The journal of physical chemistry. B, 2020, 07-02, Volume: 124, Issue:26 Topics: Fluorescence; Humans; Hypoxia; Luminescence; Naphthalimides; Neoplasms; Temperature	2020
Design, synthesis and antitumor evaluation of new 1,8-naphthalimide derivatives targeting nuclear DNA. European journal of medicinal chemistry, 2021, Jan-15, Volume: 210 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; DNA Damage; Drug Design; Humans; Mice, Nude; Naphthalimides; Neoplasms	2021
Heavy-Atom-Free Photosensitizers: From Molecular Design to Applications in the Photodynamic Therapy of Cancer. Accounts of chemical research, 2021, 01-05, Volume: 54, Issue:1 Topics: Boron; Boron Compounds; Drug Design; Humans; Light; Naphthalimides; Neoplasms; Photochemotherapy; Photosensitizing Agents; Pyrroles; Quantum Theory; Singlet Oxygen	2021
A lysosome-targeted probe for the real-time detection of hypobromous acid in living human cancer cells. The Analyst, 2021, Apr-26, Volume: 146, Issue:8 Topics: Bromates; Fluorescent Dyes; HeLa Cells; Humans; Lysosomes; Naphthalimides; Neoplasms; Optical Imaging	2021
Nucleus-targeting imaging and enhanced cytotoxicity based on naphthalimide derivatives. Bioorganic chemistry, 2021, Volume: 115 Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Nucleus; HeLa Cells; Humans; Naphthalimides; Neoplasms; Optical Imaging	2021
An OFF-ON Two-Photon Fluorescent Probe for Tracking Cell Senescence in Vivo. Journal of the American Chemical Society, 2017, 07-05, Volume: 139, Issue:26 Topics: Animals; Cellular Senescence; Fluorescent Dyes; Humans; Mice; Naphthalimides; Neoplasms; Photons; Reference Standards; Xenograft Model Antitumor Assays	2017
Synthesis, DNA Binding, and Anticancer Properties of Bis-Naphthalimide Derivatives with Lysine-Modified Polyamine Linkers. Molecules (Basel, Switzerland), 2018, Jan-29, Volume: 23, Issue:2 Topics: Antineoplastic Agents; Cell Line, Tumor; DNA, Neoplasm; Humans; Lysine; Naphthalimides; Neoplasms; Polyamines	2018
Supramolecular glyco-poly-cyclodextrin functionalized thin-layer manganese dioxide for targeted stimulus-responsive bioimaging. Chemical communications (Cambridge, England), 2018, Apr-17, Volume: 54, Issue:32 Topics: Acrylamides; Adamantane; Asialoglycoprotein Receptor; beta-Cyclodextrins; Cell Line, Tumor; Drug Stability; Fluorescent Dyes; Humans; Lectins, C-Type; Ligands; Macromolecular Substances; Manganese Compounds; Mannose Receptor; Mannose-Binding Lectins; Naphthalimides; Neoplasms; Oxides; Receptors, Cell Surface	2018
Fluorescent organometallic rhodium(I) and ruthenium(II) metallodrugs with 4-ethylthio-1,8-naphthalimide ligands: Antiproliferative effects, cellular uptake and DNA-interaction. European journal of medicinal chemistry, 2018, Aug-05, Volume: 156 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Cell Death; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fluorescent Dyes; G-Quadruplexes; Humans; Intercalating Agents; Ligands; Naphthalimides; Neoplasms; Organometallic Compounds; Rhodium; Ruthenium	2018
Fluorescent functionalised naphthalimides and their Au(i)-NHC complexes for potential use in cellular bioimaging. Dalton transactions (Cambridge, England : 2003), 2019, Feb-07, Volume: 48, Issue:5 Topics: Cell Proliferation; Coordination Complexes; Crystallography, X-Ray; Fluorescent Dyes; Gold; Heterocyclic Compounds; Humans; Ligands; Methane; Models, Molecular; Molecular Structure; Naphthalimides; Neoplasms; Tumor Cells, Cultured	2019
4-Bromo-1,8-naphthalimide derivatives as fluorogenic substrates for live cell imaging of glutathione S-transferase (GST) activity. Talanta, 2019, Nov-01, Volume: 204 Topics: Cell Line, Tumor; Enzyme Assays; Fluorescent Dyes; Glutathione S-Transferase pi; Humans; Kinetics; Microscopy, Confocal; Microscopy, Fluorescence; Naphthalimides; Neoplasms	2019
Spectroscopical study of bacteriopurpurinimide-naphthalimide conjugates for fluorescent diagnostics and photodynamic therapy. Journal of photochemistry and photobiology. B, Biology, 2014, Apr-05, Volume: 133 Topics: Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Naphthalimides; Neoplasms; Photochemotherapy; Porphyrins; Quantum Theory	2014
HKH40A downregulates GRP78/BiP expression in cancer cells. Cell death & disease, 2014, May-22, Volume: 5 Topics: Acridones; Activating Transcription Factor 6; Animals; Antineoplastic Agents; Down-Regulation; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Endoribonucleases; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; Heat-Shock Proteins; Hep G2 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Naphthalimides; Neoplasms; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Proteolysis; RNA Interference; Time Factors; Transcription, Genetic; Transfection; Tumor Burden; Unfolded Protein Response; Xenograft Model Antitumor Assays	2014
In vitro and in vivo evaluation of 2-chloroethylnitrosourea derivatives as antitumor agents. Experimental oncology, 2015, Volume: 37, Issue:1 Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; CD4 Antigens; CD8 Antigens; Cell Line, Tumor; Ethylnitrosourea; Humans; Interleukin-2 Receptor alpha Subunit; Kidney; Liver; Male; Mice; Naphthalimides; Neoplasms; Sarcoma 180	2015
Highly sensitive naphthalimide-based fluorescence polarization probe for detecting cancer cells. ACS applied materials & interfaces, 2015, May-13, Volume: 7, Issue:18 Topics: Cell Survival; Endocytosis; Fluorescence Polarization; Fluorescent Dyes; HeLa Cells; Humans; Hyaluronan Receptors; Lysosomes; Naphthalimides; Neoplasms; Subcellular Fractions	2015
Enhancement in intramolecular interactions and in vitro biological activity of a tripodal tetradentate system upon complexation. Dalton transactions (Cambridge, England : 2003), 2015, Sep-21, Volume: 44, Issue:35 Topics: Animals; Antineoplastic Agents; Apoptosis; Cattle; Coordination Complexes; Copper; Crystallography, X-Ray; DNA; Ferrous Compounds; HeLa Cells; Humans; Ligands; Models, Molecular; Naphthalimides; Neoplasms	2015
Synthesis and evaluation of novel amonafide-polyamine conjugates as anticancer agents. Chemical biology & drug design, 2017, Volume: 89, Issue:5 Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Microscopy, Fluorescence; Naphthalimides; Neoplasms; Organophosphonates; Polyamines; Transplantation, Heterologous	2017
Targeted tumor detection: guidelines for developing biotinylated diagnostics. Chemical communications (Cambridge, England), 2017, Feb-09, Volume: 53, Issue:13 Topics: 1-Naphthylamine; Biotin; Biotinylation; Fluorescent Dyes; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Microscopy, Confocal; Microscopy, Fluorescence; Naphthalimides; Neoplasms; Optical Imaging; Quinolones	2017
Direct fluorescence monitoring of the delivery and cellular uptake of a cancer-targeted RGD peptide-appended naphthalimide theragnostic prodrug. Journal of the American Chemical Society, 2012, Aug-01, Volume: 134, Issue:30 Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Humans; Microscopy, Confocal; Naphthalimides; Neoplasms; Oligopeptides; Prodrugs	2012
Predicting enhanced cell killing through PARP inhibition. Molecular cancer research : MCR, 2013, Volume: 11, Issue:1 Topics: 1-Naphthylamine; Animals; Antineoplastic Agents; Cell Death; DNA Damage; DNA Repair; Enzyme Inhibitors; Humans; Mice; Naphthalimides; Neoplasms; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolones	2013
Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis. Molecular cancer therapeutics, 2006, Volume: 5, Issue:3 Topics: 1-Naphthylamine; Animals; Cricetinae; DNA; DNA Replication; Humans; Mice; Mice, Knockout; Naphthalimides; Neoplasms; Nucleic Acid Synthesis Inhibitors; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolones; Radiation Tolerance; Radiation-Sensitizing Agents; S Phase; Tumor Cells, Cultured	2006
Novel N-oxide of naphthalimides as prodrug leads against hypoxic solid tumor: synthesis and biological evaluation. Bioorganic & medicinal chemistry letters, 2007, Apr-15, Volume: 17, Issue:8 Topics: Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Naphthalimides; Neoplasms; Oxides; Prodrugs; Structure-Activity Relationship	2007
Preclinical antitumor activity of the azonafide series of anthracene-based DNA intercalators. Anti-cancer drugs, 2001, Volume: 12, Issue:3 Topics: Adenine; Animals; Antineoplastic Agents; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Imides; Intercalating Agents; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Naphthalimides; Neoplasms; Organophosphonates; Tumor Cells, Cultured; Tumor Stem Cell Assay	2001