naphthalimides has been researched along with Acute Myelogenous Leukemia in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allen, SL; Damon, L; Egyed, M; Erba, HP; Horst, HA; Jang, JH; Lundberg, AS; Masszi, T; Mazzola, E; Neuberg, D; Pigneux, A; Powell, B; Rizzieri, D; Sekeres, MA; Selleslag, D; Solomon, SR; Stone, RM; Stuart, RK; Tallman, MS; Venugopal, P; Warzocha, K; Wetzler, M | 1 |
| Tallman, M | 1 |
| Allen, SL; Bennett, JM; Budman, DR; Capizzi, RL; Kolitz, JE; Lundberg, AS | 1 |
| Allen, SL; Lundberg, AS | 1 |
| Feldman, EJ | 1 |
| Freeman, CL; Giles, FJ; Swords, R | 1 |
| Baer, MR; Burcu, M; Ford, LA; O'Loughlin, KL | 1 |
| Benvenuto, JA; Johnston, DA; Nishioka, K | 1 |
| Benvenuto, JA; Beran, M; Estey, E; Felder, TB; Keating, M; O'Brien, S | 1 |
| Andersson, BS; Bakic, M; Beran, M; Newman, RA; Silberman, LE; Zwelling, LA | 1 |
2 review(s) available for naphthalimides and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Amonafide: a potential role in treating acute myeloid leukemia.
Topics: Adenine; Animals; Antineoplastic Agents; Clinical Trials as Topic; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Leukemia, Myeloid, Acute; Naphthalimides; Organophosphonates; Survival Rate; Treatment Outcome | 2011 |
Amonafide: a future in treatment of resistant and secondary acute myeloid leukemia?
Topics: Adenine; Antineoplastic Agents; Clinical Trials as Topic; Female; Humans; Leukemia, Myeloid, Acute; Male; Naphthalimides; Organophosphonates; Topoisomerase II Inhibitors | 2012 |
3 trial(s) available for naphthalimides and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Phase III open-label randomized study of cytarabine in combination with amonafide L-malate or daunorubicin as induction therapy for patients with secondary acute myeloid leukemia.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Induction Chemotherapy; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthalimides; Organophosphonates; Prospective Studies; Remission Induction; Time Factors; Treatment Outcome; Young Adult | 2015 |
Phase I trials of amonafide as monotherapy and in combination with cytarabine in patients with poor-risk acute myeloid leukemia.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthalimides; Organophosphonates; Remission Induction; Risk Factors; Treatment Outcome; Young Adult | 2010 |
Phase I clinical investigation of benzisoquinolinedione (amonafide) in adults with refractory or relapsed acute leukemia.
Topics: Acute Disease; Adenine; Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Female; Humans; Imides; Isoquinolines; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthalimides; Organophosphonates; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1991 |
5 other study(ies) available for naphthalimides and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Existing and emerging therapeutic options for the treatment of acute myeloid leukemia.
Topics: Adenine; Adenine Nucleotides; Aminoglycosides; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arabinonucleosides; Carbazoles; Clofarabine; Cytarabine; Dasatinib; Daunorubicin; fms-Like Tyrosine Kinase 3; Furans; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Naphthalimides; Organophosphonates; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Sesquiterpenes; Staurosporine; Stem Cell Transplantation; Thiazoles; Tretinoin | 2008 |
Does therapy-related AML have a poor prognosis, independent of the cytogenetic/molecular determinants?
Topics: Adenine; Anthracyclines; Antineoplastic Agents; Biomarkers, Tumor; Cytarabine; Cytogenetics; Female; Germany; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Naphthalimides; Naphthyridines; Organophosphonates; Prognosis; Remission Induction; Retrospective Studies; Survival Rate; Thiazoles | 2011 |
Amonafide L-malate is not a substrate for multidrug resistance proteins in secondary acute myeloid leukemia.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cyclosporins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthalimides; Neoplasm Proteins; Topoisomerase II Inhibitors | 2008 |
The correlation of response with plasma pharmacokinetics and polyamine concentrations in patients with acute myelogenous leukemia receiving amonafide.
Topics: Adenine; Antineoplastic Agents; Chromatography, High Pressure Liquid; Half-Life; Humans; Imides; Isoquinolines; Leukemia, Myeloid, Acute; Leukocyte Count; Metabolic Clearance Rate; Naphthalimides; Organophosphonates; Polyamines; Regression Analysis; Time Factors | 1993 |
In vitro toxicity and DNA cleaving capacity of benzisoquinolinedione (nafidimide; NSC 308847) in human leukemia.
Topics: Adenine; Amsacrine; Cell Line; Clone Cells; DNA; DNA Topoisomerases, Type I; Doxorubicin; Electrophoresis, Agar Gel; Humans; Imides; In Vitro Techniques; Intercalating Agents; Isoquinolines; Leukemia, Myeloid, Acute; Mathematics; Naphthalimides; Organophosphonates | 1987 |