naphthalene has been researched along with Necrosis in 9 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study further examines the involvement of 1-naphthol in the in vivo and in vitro formation of covalently bound metabolites and pulmonary bronchiolar necrosis by naphthalene." | 7.67 | Evidence that 1-naphthol is not an obligate intermediate in the covalent binding and the pulmonary bronchiolar necrosis by naphthalene. ( Bahnson, LS; Buckpitt, AR; Franklin, RB, 1985) |
| "Histopathological analysis showed that naphthalene-induced Clara cell necrosis was more prominent in the lungs of female mice as compared to male mice." | 3.75 | Gender differences in pulmonary regenerative response to naphthalene-induced bronchiolar epithelial cell injury. ( Cutz, E; Hu, J; Kushwah, R; Oliver, JR; Waddell, TK; Wu, J; Yeger, H, 2009) |
| "The administration of single doses of coumarin to the rat was found to produce hepatic centrilobular necrosis and also to depress a number of hepatic enzyme activities within 24 h." | 3.67 | Investigations into the mechanism of coumarin-induced hepatotoxicity in the rat. ( Lake, BG, 1984) |
| "Intraperitoneal administration of single doses of the volatile aromatic hydrocarbon, naphthalene, resulted in dose-dependent bronchiolar epithelial cell necrosis in mice." | 3.67 | Tolerance to multiple doses of the pulmonary toxicant, naphthalene. ( Buckpitt, AR; Kanekal, S; O'Brien, KA; Plopper, CG; Suverkropp, C, 1989) |
| " This study further examines the involvement of 1-naphthol in the in vivo and in vitro formation of covalently bound metabolites and pulmonary bronchiolar necrosis by naphthalene." | 3.67 | Evidence that 1-naphthol is not an obligate intermediate in the covalent binding and the pulmonary bronchiolar necrosis by naphthalene. ( Bahnson, LS; Buckpitt, AR; Franklin, RB, 1985) |
| " This has decisive toxicological implications, which could be demonstrated by comparing the lung-specific toxic effects of naphthalenes in mouse: the lack of ring oxidation correlates well with lack of lung toxicity while, vice versa, the extent of enzymatic oxidative attack at the aromatic ring structure results in a toxic pattern that is observed with naphthalene and its monomethyl derivatives." | 2.40 | Metabolism and toxicity of diisopropylnaphthalene as compared to naphthalene and monoalkyl naphthalenes: a minireview. ( Höke, H; Zellerhoff, R, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oliver, JR | 2 |
| Kushwah, R | 2 |
| Wu, J | 2 |
| Cutz, E | 2 |
| Yeger, H | 2 |
| Waddell, TK | 2 |
| Hu, J | 2 |
| Pan, J | 1 |
| Bado-Nilles, A | 1 |
| Quentel, C | 1 |
| Mazurais, D | 1 |
| Zambonino-Infante, JL | 1 |
| Auffret, M | 1 |
| Thomas-Guyon, H | 1 |
| Le Floch, S | 1 |
| Vijayavel, K | 1 |
| Balasubramanian, MP | 1 |
| Lake, BG | 1 |
| Höke, H | 1 |
| Zellerhoff, R | 1 |
| Kanekal, S | 2 |
| Plopper, C | 1 |
| Morin, D | 1 |
| Buckpitt, A | 1 |
| O'Brien, KA | 1 |
| Suverkropp, C | 1 |
| Plopper, CG | 1 |
| Buckpitt, AR | 2 |
| Bahnson, LS | 1 |
| Franklin, RB | 1 |
1 review available for naphthalene and Necrosis
| Article | Year |
|---|---|
Metabolism and toxicity of diisopropylnaphthalene as compared to naphthalene and monoalkyl naphthalenes: a minireview.
Topics: Anemia, Hemolytic; Animals; Cataract; Humans; Lung; Naphthalenes; Necrosis | 1998 |
8 other studies available for naphthalene and Necrosis
| Article | Year |
|---|---|
Gender differences in pulmonary regenerative response to naphthalene-induced bronchiolar epithelial cell injury.
Topics: Acute Lung Injury; Age Factors; Animals; Bronchioles; Cell Division; Dose-Response Relationship, Dru | 2009 |
Elf3 plays a role in regulating bronchiolar epithelial repair kinetics following Clara cell-specific injury.
Topics: Animals; Bronchioles; Cell Differentiation; Cell Proliferation; DNA-Binding Proteins; Epithelial Cel | 2011 |
In vivo effects of the soluble fraction of light cycle oil on immune functions in the European sea bass, Dicentrarchus labrax (Linné).
Topics: Animals; Bass; Bile; Environmental Exposure; Fuel Oils; Gene Expression Regulation; Immune System; I | 2011 |
DNA damage and cell necrosis induced by naphthalene due to the modulation of biotransformation enzymes in an estuarine crab Scylla serrata.
Topics: Animals; Biotransformation; Brachyura; DNA Damage; Female; Hemolymph; Hepatopancreas; Naphthalenes; | 2008 |
Investigations into the mechanism of coumarin-induced hepatotoxicity in the rat.
Topics: Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury; Coumarins; Kinetics; Liver; Liver D | 1984 |
Metabolic activation and bronchiolar Clara cell necrosis from naphthalene in the isolated perfused mouse lung.
Topics: Animals; Biotransformation; Bronchi; Dose-Response Relationship, Drug; Epithelium; Glutathione; Male | 1990 |
Tolerance to multiple doses of the pulmonary toxicant, naphthalene.
Topics: Animals; Bronchi; Dose-Response Relationship, Drug; Drug Tolerance; Glutathione; Lung; Male; Mice; M | 1989 |
Evidence that 1-naphthol is not an obligate intermediate in the covalent binding and the pulmonary bronchiolar necrosis by naphthalene.
Topics: Animals; Biotransformation; Bronchial Diseases; In Vitro Techniques; Lung; Male; Mice; Microsomes, L | 1985 |