naphthalene has been researched along with Hyperplasia in 5 studies
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Naphthalene (NA) was shown to be carcinogenic, causing respiratory epithelial adenoma in the nasal cavity of male F344 rats and olfactory epithelial neuroblastoma in female F344 rats at exposure concentrations of 10-60 ppm in a 2-year inhalation study conducted by the National Toxicology Program." | 1.38 | Nasal epithelial lesions in F344 rats following a 90-day inhalation exposure to naphthalene. ( Dodd, DE; Gross, EA; Miller, RA; Wong, BA, 2012) |
| "Naphthalene is an aromatic hydrocarbon that, at the dose used in this study, selectively destroys nonciliated bronchial epithelial cells (Clara cells) through cytochrome P-450-mediated metabolic activation into cytotoxic epoxides." | 1.30 | Cell proliferation contributes to PNEC hyperplasia after acute airway injury. ( McBride, JT; Peake, JL; Pinkerton, KE; Stevens, TP; Stripp, BR, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poulsen, TT | 1 |
| Naizhen, X | 1 |
| Poulsen, HS | 1 |
| Linnoila, RI | 1 |
| Dodd, DE | 1 |
| Wong, BA | 1 |
| Gross, EA | 1 |
| Miller, RA | 1 |
| KUHL, I | 1 |
| Stevens, TP | 1 |
| McBride, JT | 1 |
| Peake, JL | 1 |
| Pinkerton, KE | 1 |
| Stripp, BR | 2 |
| Hong, KU | 1 |
| Reynolds, SD | 1 |
| Giangreco, A | 1 |
| Hurley, CM | 1 |
5 other studies available for naphthalene and Hyperplasia
| Article | Year |
|---|---|
Acute damage by naphthalene triggers expression of the neuroendocrine marker PGP9.5 in airway epithelial cells.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cyclin-Dependent Kinase Inhibitor p27; Epithelial Cells; Hy | 2008 |
Nasal epithelial lesions in F344 rats following a 90-day inhalation exposure to naphthalene.
Topics: Administration, Inhalation; Animals; Carcinogens; Dose-Response Relationship, Drug; Female; Hyperpla | 2012 |
[Allergic-hyperergic symptoms in mice after beta-naphthalamine administration, manifested by periarteritis nodosa, activation of the reticuloendothelial system, plasma cell hyperplasia and paraproteinosis of various organs].
Topics: Animals; Hyperplasia; Hypersensitivity; Immune System Diseases; Mice; Mononuclear Phagocyte System; | 1956 |
Cell proliferation contributes to PNEC hyperplasia after acute airway injury.
Topics: Acute Disease; Animals; Calcitonin Gene-Related Peptide; Cell Division; Epithelium; Histocytochemist | 1997 |
Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion.
Topics: Animals; Bronchi; Calcitonin Gene-Related Peptide; Cell Communication; Cell Division; Ganciclovir; H | 2001 |