naphthalene has been researched along with Disease Models, Animal in 35 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether a diet containing excessive amounts of milk aggravates naphthalene-initiated cataracts in a common animal model of age-related human cataract." | 7.78 | Excessive milk intake as a risk factor, probably associated with oxidative stress, in experimental naphthalene-initiated cataract in rats. ( Chen, Y; Jiang, YX; Miu, AZ; Wu, JH; Yi, L; Zhang, SH; Zhang, SJ, 2012) |
| "To evaluate whether alpha-lipoic acid (LA) inhibits lens opacity of naphthalene-induced cataract by altering post-translational modifications (PTMs) and protecting the chaperone activity of alpha-crystallins." | 7.76 | alpha-Lipoic acid alters post-translational modifications and protects the chaperone activity of lens alpha-crystallin in naphthalene-induced cataract. ( Chen, Y; Fang, Y; Jang, Y; Wei, L; Wu, X; Yan, G; Yi, L; Zhou, X, 2010) |
| "To examine the retinotoxic effect of naphthalene, a powerful oxidative agent and a well-known cataractogenic agent." | 7.69 | Subretinal neovascularization after naphthalene damage to the rabbit retina. ( Migliavacca, L; Miglior, S; Orzalesi, N, 1994) |
| "Naphthalene-induced rat cataract is a useful experimental cataract--however, because of its short survival period, studies using this model have been for limited purposes." | 7.69 | A mild progression type of naphthalene-induced cataract in brown-Norway rats. ( Kojima, M; Murano, H; Nagata, M; Sasaki, K, 1995) |
| "Naphthalene-induced cataract in rat lenses can be completely prevented by AL01576, an aldose reductase inhibitor (ARI)." | 7.69 | Inhibition of naphthalene cataract in rats by aldose reductase inhibitors. ( Lou, MF; Xu, GT; York, B; Zigler, S, 1996) |
| "The progression of naphthalene cataracts induced in Brown-Norway rats and Sprague-Dawley rats was compared." | 7.68 | Differences in naphthalene cataract formation between albino and pigmented rat eyes. ( Kojima, M; Murano, H; Sasaki, K, 1993) |
| "The topographic distribution of enzyme activities in normal rat lenses and their changes occurring during naphthalene cataract development were investigated." | 7.68 | Enzymatic distribution patterns of rat lenses and the changes that occur during naphthalene cataract development. ( Kojima, M, 1992) |
| "This investigation compared the effects of two types of aldose reductase inhibitors on several biochemical parameters in naphthalene-induced cataract of the rat over a time span of 102 days of treatment." | 7.68 | Naphthalene-induced cataract in the rat. II. Contrasting effects of two aldose reductase inhibitors on glutathione and glutathione redox enzymes. ( Holleschau, AM; Rathbun, WB; Tao, RV, 1991) |
| "The naphthalene cataract in the pigmented rabbit, in contrast to the corresponding model in the pigmented rat, is characterized by a rather unstable cataract development during the later stages." | 7.68 | Regional enzyme profiles in rabbit lenses with early stages of naphthalene cataract. ( Hockwin, O; Selzer, M; Wegener, A, 1991) |
| "The development of naphthalene cataract in rabbits is described, photographed in detail, and compared with different types of senile cataract in man." | 7.67 | Is the experimental naphthalene cataract a model for human senile cataract? ( Pau, H; Rossa, V, 1988) |
| "These findings suggested that ACE2 activation by resorcinolnaphthalein improved endothelial function and suppressed neointimal formation in the prevention of severe PAH by the mechanism of mediating the levels of the components of the renin-angiotensin system." | 3.79 | ACE2 activation confers endothelial protection and attenuates neointimal lesions in prevention of severe pulmonary arterial hypertension in rats. ( Li, G; Li, X; Li, Z; Liu, A; Liu, Y; Su, J; Sun, L; Xu, Y; Zhu, Y, 2013) |
| "To determine whether a diet containing excessive amounts of milk aggravates naphthalene-initiated cataracts in a common animal model of age-related human cataract." | 3.78 | Excessive milk intake as a risk factor, probably associated with oxidative stress, in experimental naphthalene-initiated cataract in rats. ( Chen, Y; Jiang, YX; Miu, AZ; Wu, JH; Yi, L; Zhang, SH; Zhang, SJ, 2012) |
| "Gefitinib treatment after naphthalene prolonged neutrophil sequestration and worsened acute lung injury." | 3.77 | EGFR tyrosine kinase inhibition worsens acute lung injury in mice with repairing airway epithelium. ( Hamada, N; Harada, C; Kawaguchi, T; Kuwano, K; Maeyama, T; Nakanishi, Y; Ogata-Suetsugu, S; Souzaki, R; Taguchi, T; Tajiri, T; Yamada, M, 2011) |
| "To evaluate whether alpha-lipoic acid (LA) inhibits lens opacity of naphthalene-induced cataract by altering post-translational modifications (PTMs) and protecting the chaperone activity of alpha-crystallins." | 3.76 | alpha-Lipoic acid alters post-translational modifications and protects the chaperone activity of lens alpha-crystallin in naphthalene-induced cataract. ( Chen, Y; Fang, Y; Jang, Y; Wei, L; Wu, X; Yan, G; Yi, L; Zhou, X, 2010) |
| "To examine the retinotoxic effect of naphthalene, a powerful oxidative agent and a well-known cataractogenic agent." | 3.69 | Subretinal neovascularization after naphthalene damage to the rabbit retina. ( Migliavacca, L; Miglior, S; Orzalesi, N, 1994) |
| "Naphthalene-induced rat cataract is a useful experimental cataract--however, because of its short survival period, studies using this model have been for limited purposes." | 3.69 | A mild progression type of naphthalene-induced cataract in brown-Norway rats. ( Kojima, M; Murano, H; Nagata, M; Sasaki, K, 1995) |
| "Naphthalene-induced cataract in rat lenses can be completely prevented by AL01576, an aldose reductase inhibitor (ARI)." | 3.69 | Inhibition of naphthalene cataract in rats by aldose reductase inhibitors. ( Lou, MF; Xu, GT; York, B; Zigler, S, 1996) |
| "The progression of naphthalene cataracts induced in Brown-Norway rats and Sprague-Dawley rats was compared." | 3.68 | Differences in naphthalene cataract formation between albino and pigmented rat eyes. ( Kojima, M; Murano, H; Sasaki, K, 1993) |
| "The topographic distribution of enzyme activities in normal rat lenses and their changes occurring during naphthalene cataract development were investigated." | 3.68 | Enzymatic distribution patterns of rat lenses and the changes that occur during naphthalene cataract development. ( Kojima, M, 1992) |
| "This investigation compared the effects of two types of aldose reductase inhibitors on several biochemical parameters in naphthalene-induced cataract of the rat over a time span of 102 days of treatment." | 3.68 | Naphthalene-induced cataract in the rat. II. Contrasting effects of two aldose reductase inhibitors on glutathione and glutathione redox enzymes. ( Holleschau, AM; Rathbun, WB; Tao, RV, 1991) |
| "The naphthalene cataract in the pigmented rabbit, in contrast to the corresponding model in the pigmented rat, is characterized by a rather unstable cataract development during the later stages." | 3.68 | Regional enzyme profiles in rabbit lenses with early stages of naphthalene cataract. ( Hockwin, O; Selzer, M; Wegener, A, 1991) |
| "The development of naphthalene cataract in rabbits is described, photographed in detail, and compared with different types of senile cataract in man." | 3.67 | Is the experimental naphthalene cataract a model for human senile cataract? ( Pau, H; Rossa, V, 1988) |
| "Depletion of epithelial cells after lung injury prompts proliferation and epithelial mesenchymal transition (EMT) of progenitor cells, and this repopulates the lost epithelial layer." | 1.51 | DNA replication in progenitor cells and epithelial regeneration after lung injury requires the oncoprotein MDM2. ( Deb, S; Mikkelsen, R; Palit Deb, S; Rabender, C; Singh, S; Vaughan, CA, 2019) |
| "Mice treated with naphthalene were used for the bronchiolar epithelium injury model, and mice treated with bleomycin were used for the alveolar epithelium injury model." | 1.39 | A change in the number of CCSP(pos)/SPC(pos) cells in mouse lung during development, growth, and repair. ( Ishiguro, A; Kijima, H; Nukiwa, T; Saijo, Y; Sun, R; Takahata, T; Ye, X; Zhou, Q, 2013) |
| "Clara cell senescence in COPD patients was accelerated and accompanied by p38 MAPK activation." | 1.37 | Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury. ( Aoshiba, K; Nagai, A; Onizawa, S; Zhou, F, 2011) |
| " Hemolytic anemia was also found in G6PD-deficient mice at this dosage of naphthalene." | 1.37 | Development of a novel mouse model of severe glucose-6-phosphate dehydrogenase (G6PD)-deficiency for in vitro and in vivo assessment of hemolytic toxicity to red blood cells. ( Fok, TF; Fung, KP; Gu, GJ; James, AE; Ko, CH; Li, CL; Li, K; Ng, PC; Wong, RP, 2011) |
| "Naphthalene is a volatile hydrocarbon that causes dose-, species-, and cell type-dependent cytotoxicity after acute exposure and hyperplasia/neoplasia after lifetime exposures in rodents." | 1.36 | Formation of covalently bound protein adducts from the cytotoxicant naphthalene in nasal epithelium: species comparisons. ( Buckpitt, A; DeStefano-Shields, C; Morin, D, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (8.57) | 18.7374 |
| 1990's | 11 (31.43) | 18.2507 |
| 2000's | 5 (14.29) | 29.6817 |
| 2010's | 16 (45.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, S | 1 |
| Vaughan, CA | 1 |
| Rabender, C | 1 |
| Mikkelsen, R | 1 |
| Deb, S | 1 |
| Palit Deb, S | 1 |
| Li, G | 1 |
| Liu, Y | 1 |
| Zhu, Y | 1 |
| Liu, A | 1 |
| Xu, Y | 1 |
| Li, X | 2 |
| Li, Z | 1 |
| Su, J | 1 |
| Sun, L | 1 |
| Sun, R | 1 |
| Zhou, Q | 1 |
| Ye, X | 1 |
| Takahata, T | 1 |
| Ishiguro, A | 1 |
| Kijima, H | 1 |
| Nukiwa, T | 1 |
| Saijo, Y | 1 |
| Aoshiba, K | 3 |
| Tsuji, T | 2 |
| Itoh, M | 2 |
| Semba, S | 1 |
| Yamaguchi, K | 1 |
| Nakamura, H | 2 |
| Watanabe, H | 1 |
| Royce, SG | 2 |
| Patel, KP | 1 |
| Samuel, CS | 1 |
| García-Sanmartín, J | 1 |
| Larrayoz, IM | 1 |
| Martínez, A | 1 |
| Watanabe, O | 1 |
| Kikuchi, R | 1 |
| Raiser, DM | 1 |
| Zacharek, SJ | 1 |
| Roach, RR | 1 |
| Curtis, SJ | 1 |
| Sinkevicius, KW | 1 |
| Gludish, DW | 1 |
| Kim, CF | 1 |
| Cruzan, G | 1 |
| Bus, J | 1 |
| Banton, M | 1 |
| Gingell, R | 1 |
| Carlson, G | 1 |
| DeStefano-Shields, C | 1 |
| Morin, D | 1 |
| Buckpitt, A | 1 |
| Chen, Y | 2 |
| Yi, L | 2 |
| Yan, G | 1 |
| Fang, Y | 1 |
| Jang, Y | 1 |
| Wu, X | 1 |
| Zhou, X | 1 |
| Wei, L | 1 |
| Harada, C | 1 |
| Kawaguchi, T | 1 |
| Ogata-Suetsugu, S | 1 |
| Yamada, M | 1 |
| Hamada, N | 1 |
| Maeyama, T | 1 |
| Souzaki, R | 1 |
| Tajiri, T | 1 |
| Taguchi, T | 1 |
| Kuwano, K | 1 |
| Nakanishi, Y | 1 |
| Gupte, R | 1 |
| Patil, R | 1 |
| Liu, J | 1 |
| Wang, Y | 1 |
| Lee, SC | 1 |
| Fujiwara, Y | 1 |
| Fells, J | 1 |
| Bolen, AL | 1 |
| Emmons-Thompson, K | 1 |
| Yates, CR | 1 |
| Siddam, A | 1 |
| Panupinthu, N | 1 |
| Pham, TC | 1 |
| Baker, DL | 1 |
| Parrill, AL | 1 |
| Mills, GB | 1 |
| Tigyi, G | 1 |
| Miller, DD | 1 |
| Karagiannis, TC | 1 |
| Tang, MM | 1 |
| Orlowski, C | 1 |
| El-Osta, A | 1 |
| Tang, ML | 1 |
| Zhou, F | 1 |
| Onizawa, S | 1 |
| Nagai, A | 1 |
| Ko, CH | 1 |
| Li, K | 1 |
| Li, CL | 1 |
| Ng, PC | 1 |
| Fung, KP | 1 |
| James, AE | 1 |
| Wong, RP | 1 |
| Gu, GJ | 1 |
| Fok, TF | 1 |
| Jiang, YX | 1 |
| Miu, AZ | 1 |
| Zhang, SJ | 1 |
| Wu, JH | 1 |
| Zhang, SH | 1 |
| Sutherland, KM | 1 |
| Edwards, PC | 1 |
| Combs, TJ | 1 |
| Van Winkle, LS | 3 |
| Brown, CD | 1 |
| Shimizu, JA | 1 |
| Gunderson, AD | 1 |
| Evans, MJ | 1 |
| Plopper, CG | 1 |
| Serikov, VB | 1 |
| Popov, B | 1 |
| Mikhailov, VM | 1 |
| Gupta, N | 1 |
| Matthay, MA | 1 |
| Yildirim, AO | 1 |
| Veith, M | 1 |
| Rausch, T | 1 |
| Müller, B | 1 |
| Kilb, P | 1 |
| Fehrenbach, H | 1 |
| Gupta, PP | 1 |
| Pandey, DN | 1 |
| Pandey, DJ | 1 |
| Sharma, AL | 1 |
| Srivastava, RK | 1 |
| Mishra, SS | 1 |
| Orzalesi, N | 1 |
| Migliavacca, L | 1 |
| Miglior, S | 1 |
| Murano, H | 2 |
| Kojima, M | 4 |
| Sasaki, K | 3 |
| Nagata, M | 1 |
| Lou, MF | 1 |
| Xu, GT | 1 |
| Zigler, S | 1 |
| York, B | 1 |
| Kilanowicz, A | 1 |
| Czerski, B | 1 |
| Sapota, A | 1 |
| Tao, RV | 1 |
| Holleschau, AM | 1 |
| Rathbun, WB | 1 |
| Prost, M | 1 |
| Gerkowicz, K | 1 |
| Katski, W | 1 |
| Gerkowicz, M | 1 |
| Jedrzejewski, D | 1 |
| Selzer, M | 1 |
| Wegener, A | 2 |
| Hockwin, O | 2 |
| Laser, H | 1 |
| Rossa, V | 2 |
| Kluxen, G | 1 |
| Pau, H | 1 |
2 reviews available for naphthalene and Disease Models, Animal
| Article | Year |
|---|---|
Stem cell biology in the lung and lung cancers: using pulmonary context and classic approaches.
Topics: Animals; Bleomycin; Disease Models, Animal; Homeostasis; Humans; Lung; Lung Injury; Lung Neoplasms; | 2008 |
Mouse specific lung tumors from CYP2F2-mediated cytotoxic metabolism: an endpoint/toxic response where data from multiple chemicals converge to support a mode of action.
Topics: Adenocarcinoma; Adenoma; Animals; Bronchioles; Carcinogens; Cell Proliferation; Coumarins; Cytochrom | 2009 |
33 other studies available for naphthalene and Disease Models, Animal
| Article | Year |
|---|---|
DNA replication in progenitor cells and epithelial regeneration after lung injury requires the oncoprotein MDM2.
Topics: Animals; Cell Proliferation; Disease Models, Animal; DNA Damage; DNA Replication; Epithelial Cells; | 2019 |
ACE2 activation confers endothelial protection and attenuates neointimal lesions in prevention of severe pulmonary arterial hypertension in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Cytoprot | 2013 |
A change in the number of CCSP(pos)/SPC(pos) cells in mouse lung during development, growth, and repair.
Topics: Acute Lung Injury; Animals; Bleomycin; Bronchi; Cell Count; Disease Models, Animal; Epithelial Cells | 2013 |
A murine model of airway fibrosis induced by repeated naphthalene exposure.
Topics: Animals; Cell Proliferation; Connective Tissue Growth Factor; Disease Models, Animal; Dose-Response | 2014 |
Characterization of a novel model incorporating airway epithelial damage and related fibrosis to the pathogenesis of asthma.
Topics: Animals; Apoptosis; Asthma; Bronchi; Bronchial Hyperreactivity; Collagen; Disease Models, Animal; Ep | 2014 |
Adrenomedullin regulates club cell recovery following lung epithelial injury.
Topics: Adrenomedullin; Animals; Disease Models, Animal; Lung Injury; Mice; Mice, Inbred C57BL; Mice, Knocko | 2016 |
Little evidence for epithelial-mesenchymal transition in a murine model of airway fibrosis induced by repeated naphthalene exposure.
Topics: Animals; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fluorescent Antibody Technique; | 2016 |
Formation of covalently bound protein adducts from the cytotoxicant naphthalene in nasal epithelium: species comparisons.
Topics: Animals; Disease Models, Animal; Environmental Pollutants; Female; Humans; In Vitro Techniques; Lung | 2010 |
alpha-Lipoic acid alters post-translational modifications and protects the chaperone activity of lens alpha-crystallin in naphthalene-induced cataract.
Topics: Acetylation; alpha-Crystallins; Animals; Antioxidants; Cataract; Chromatography, High Pressure Liqui | 2010 |
EGFR tyrosine kinase inhibition worsens acute lung injury in mice with repairing airway epithelium.
Topics: Acute Lung Injury; Airway Remodeling; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; | 2011 |
Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Enzyme Inhi | 2011 |
Molecular model of naphthalene-induced DNA damage in the murine lung.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Disease | 2012 |
Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury.
Topics: Aged; Analysis of Variance; Animals; beta-Galactosidase; Cell Line, Tumor; Cell Proliferation; Cellu | 2011 |
Development of a novel mouse model of severe glucose-6-phosphate dehydrogenase (G6PD)-deficiency for in vitro and in vivo assessment of hemolytic toxicity to red blood cells.
Topics: Anemia, Hemolytic; Animals; Breeding; Disease Models, Animal; Erythrocytes; Female; Glucosephosphate | 2011 |
Excessive milk intake as a risk factor, probably associated with oxidative stress, in experimental naphthalene-initiated cataract in rats.
Topics: Animals; Cataract; Diet; Disease Models, Animal; Female; Glutathione; Lens, Crystalline; Male; Malon | 2012 |
Sex differences in the development of airway epithelial tolerance to naphthalene.
Topics: Air Pollution; Animals; Bronchi; Cytochrome P-450 Enzyme System; Disease Models, Animal; Drug Tolera | 2012 |
Impaired recovery from naphthalene-induced bronchiolar epithelial injury in mice exposed to aged and diluted sidestream cigarette smoke.
Topics: Animals; Bronchi; Bronchial Diseases; Disease Models, Animal; Drug Therapy, Combination; Male; Mice; | 2004 |
Evidence of temporary airway epithelial repopulation and rare clonal formation by BM-derived cells following naphthalene injury in mice.
Topics: Animals; Bone Marrow Cells; Cell Proliferation; Cells, Cultured; Clone Cells; Disease Models, Animal | 2007 |
Keratinocyte growth factor protects against Clara cell injury induced by naphthalene.
Topics: Acute Lung Injury; Animals; Bronchioles; Cytochrome P-450 Enzyme System; Disease Models, Animal; Epi | 2008 |
Aspirin in experimental cataractogenesis.
Topics: Animals; Aspirin; Cataract; Disease Models, Animal; Female; Galactose; Male; Naphthalenes; Rabbits; | 1984 |
Subretinal neovascularization after naphthalene damage to the rabbit retina.
Topics: Animals; Cataract; Cell Division; Disease Models, Animal; Fluorescein Angiography; Fundus Oculi; Gas | 1994 |
Differences in naphthalene cataract formation between albino and pigmented rat eyes.
Topics: Albinism, Oculocutaneous; Animals; Cataract; Disease Models, Animal; Lens, Crystalline; Male; Naphth | 1993 |
A mild progression type of naphthalene-induced cataract in brown-Norway rats.
Topics: Animals; Cataract; Disease Models, Animal; Female; Lens, Crystalline; Naphthalenes; Photography; Rat | 1995 |
Inhibition of naphthalene cataract in rats by aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cataract; Culture Techniques; Disease Models, Animal; Enzyme Inhibitors | 1996 |
The disposition and metabolism of naphthalene in rats.
Topics: Animals; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Injections, Intraperitoneal; | 1999 |
Application of a new Scheimpflug camera (EAS-1000) to animal cataract models.
Topics: Animals; Cataract; Disease Models, Animal; Dogs; Lens, Crystalline; Macaca; Mice; Naphthalenes; Opht | 1992 |
Enzymatic distribution patterns of rat lenses and the changes that occur during naphthalene cataract development.
Topics: Animals; Cataract; Disease Models, Animal; Female; Image Processing, Computer-Assisted; Lens, Crysta | 1992 |
Naphthalene-induced cataract in the rat. II. Contrasting effects of two aldose reductase inhibitors on glutathione and glutathione redox enzymes.
Topics: Aldehyde Reductase; Animals; Body Weight; Cataract; Disease Models, Animal; Female; Fluorenes; Gluta | 1991 |
[Studies of the changes in crystalline lens transparency in rabbits with experimental cataract].
Topics: Absorption; Animals; Cataract; Disease Models, Animal; Equipment Design; Lens, Crystalline; Light; N | 1991 |
Regional enzyme profiles in rabbit lenses with early stages of naphthalene cataract.
Topics: Animals; Cataract; Crystallins; Disease Models, Animal; Female; Lens, Crystalline; Lyases; Naphthale | 1991 |
Ultraviolet filter photography to demonstrate the fluorescence of animal lenses with different cataract models.
Topics: Animals; Cataract; Densitometry; Disease Models, Animal; Female; Filtration; Fluorescence; Lens, Cry | 1990 |
[Significance of experimental cataracts for the development of senile cataracts exemplified by naphthalene and dimethyl sulfoxide-induced lens opacities].
Topics: Animals; Cataract; Dimethyl Sulfoxide; Disease Models, Animal; Lens, Crystalline; Naphthalenes; Rabb | 1988 |
Is the experimental naphthalene cataract a model for human senile cataract?
Topics: Aging; Animals; Cataract; Disease Models, Animal; Humans; Naphthalenes | 1988 |