Page last updated: 2024-10-19

naphthalene and Chronic Lung Injury

naphthalene has been researched along with Chronic Lung Injury in 15 studies

Research Excerpts

ExcerptRelevanceReference
"Inflammation was evaluated in bronchoalveolar lavage (BAL) fluid, and epithelial barrier integrity was assessed by measuring BAL protein and Evans Blue dye permeability."2.80Fibroblast growth factor 2 is required for epithelial recovery, but not for pulmonary fibrosis, in response to bleomycin. ( Elton, TJ; Guzy, RD; Mecham, RP; Ornitz, DM; Stoilov, I, 2015)
"Depletion of epithelial cells after lung injury prompts proliferation and epithelial mesenchymal transition (EMT) of progenitor cells, and this repopulates the lost epithelial layer."1.51DNA replication in progenitor cells and epithelial regeneration after lung injury requires the oncoprotein MDM2. ( Deb, S; Mikkelsen, R; Palit Deb, S; Rabender, C; Singh, S; Vaughan, CA, 2019)
"Clara cell senescence in COPD patients was accelerated and accompanied by p38 MAPK activation."1.37Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury. ( Aoshiba, K; Nagai, A; Onizawa, S; Zhou, F, 2011)
"Naphthalene is an aromatic hydrocarbon that, at the dose used in this study, selectively destroys nonciliated bronchial epithelial cells (Clara cells) through cytochrome P-450-mediated metabolic activation into cytotoxic epoxides."1.30Cell proliferation contributes to PNEC hyperplasia after acute airway injury. ( McBride, JT; Peake, JL; Pinkerton, KE; Stevens, TP; Stripp, BR, 1997)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's2 (13.33)29.6817
2010's12 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Singh, S1
Vaughan, CA1
Rabender, C1
Mikkelsen, R1
Deb, S1
Palit Deb, S1
Fang, S1
Zhang, S1
Dai, H1
Hu, X1
Li, C2
Xing, Y2
Lee, KP1
Park, SJ1
Kang, S1
Koh, JM1
Sato, K1
Chung, HY1
Okajima, F1
Im, DS1
Milman Krentsis, I1
Rosen, C1
Shezen, E1
Aronovich, A1
Nathanson, B1
Bachar-Lustig, E1
Berkman, N1
Assayag, M1
Shakhar, G1
Feferman, T1
Orgad, R1
Reisner, Y1
Guzy, RD1
Stoilov, I1
Elton, TJ1
Mecham, RP1
Ornitz, DM1
García-Sanmartín, J1
Larrayoz, IM1
Martínez, A1
Carraro, G1
Perin, L1
Sedrakyan, S1
Giuliani, S1
Tiozzo, C2
Lee, J1
Turcatel, G1
De Langhe, SP2
Driscoll, B1
Bellusci, S2
Minoo, P2
Atala, A1
De Filippo, RE1
Warburton, D1
Raiser, DM1
Zacharek, SJ1
Roach, RR1
Curtis, SJ1
Sinkevicius, KW1
Gludish, DW1
Kim, CF1
Krause, A1
Xu, Y1
Joh, J1
Hubner, R1
Gess, A1
Ilic, T1
Worgall, S1
Greeley, MA1
Van Winkle, LS1
Edwards, PC1
Plopper, CG1
Sonar, SS1
Schwinge, D1
Kilic, A1
Yildirim, AO1
Conrad, ML1
Seidler, K1
Müller, B1
Renz, H1
Nockher, WA1
Li, A1
Chan, B1
Heisterkamp, N1
Groffen, J1
Borok, Z1
Zhou, F1
Onizawa, S1
Nagai, A1
Aoshiba, K1
Volckaert, T1
Dill, E1
Campbell, A1
Majka, S1
Stevens, TP1
McBride, JT1
Peake, JL1
Pinkerton, KE1
Stripp, BR1

Reviews

1 review available for naphthalene and Chronic Lung Injury

ArticleYear
Stem cell biology in the lung and lung cancers: using pulmonary context and classic approaches.
    Cold Spring Harbor symposia on quantitative biology, 2008, Volume: 73

    Topics: Animals; Bleomycin; Disease Models, Animal; Homeostasis; Humans; Lung; Lung Injury; Lung Neoplasms;

2008

Trials

1 trial available for naphthalene and Chronic Lung Injury

ArticleYear
Fibroblast growth factor 2 is required for epithelial recovery, but not for pulmonary fibrosis, in response to bleomycin.
    American journal of respiratory cell and molecular biology, 2015, Volume: 52, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage; Female; Fibroblast Growth F

2015

Other Studies

13 other studies available for naphthalene and Chronic Lung Injury

ArticleYear
DNA replication in progenitor cells and epithelial regeneration after lung injury requires the oncoprotein MDM2.
    JCI insight, 2019, 10-17, Volume: 4, Issue:20

    Topics: Animals; Cell Proliferation; Disease Models, Animal; DNA Damage; DNA Replication; Epithelial Cells;

2019
The role of pulmonary mesenchymal cells in airway epithelium regeneration during injury repair.
    Stem cell research & therapy, 2019, 12-02, Volume: 10, Issue:1

    Topics: Acute Disease; Animals; Cell Differentiation; Epithelial Cells; Epithelium; Lipopolysaccharides; Lun

2019
ω-3 Polyunsaturated fatty acids accelerate airway repair by activating FFA4 in club cells.
    American journal of physiology. Lung cellular and molecular physiology, 2017, 06-01, Volume: 312, Issue:6

    Topics: Animals; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Separation; Docosahexaenoic A

2017
Lung Injury Repair by Transplantation of Adult Lung Cells Following Preconditioning of Recipient Mice.
    Stem cells translational medicine, 2018, Volume: 7, Issue:1

    Topics: Animals; Cells, Cultured; Epithelial Cells; Female; Guided Tissue Regeneration; Lung; Lung Injury; M

2018
Adrenomedullin regulates club cell recovery following lung epithelial injury.
    Histology and histopathology, 2016, Volume: 31, Issue:6

    Topics: Adrenomedullin; Animals; Disease Models, Animal; Lung Injury; Mice; Mice, Inbred C57BL; Mice, Knocko

2016
Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages.
    Stem cells (Dayton, Ohio), 2008, Volume: 26, Issue:11

    Topics: Amniotic Fluid; Animals; Cell Differentiation; Cell Lineage; Chemokine CXCL12; DNA-Binding Proteins;

2008
Overexpression of sonic Hedgehog in the lung mimics the effect of lung injury and compensatory lung growth on pulmonary Sca-1 and CD34 positive cells.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2010, Volume: 18, Issue:2

    Topics: Adenoviridae; Animals; Antigens, CD34; Antigens, Ly; Cells, Cultured; Female; Flow Cytometry; Fluore

2010
Airway trefoil factor expression during naphthalene injury and repair.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 113, Issue:2

    Topics: Animals; Bronchioles; Lung; Lung Injury; Male; Mice; Mucins; Muscle Proteins; Naphthalenes; Peptides

2010
Nerve growth factor enhances Clara cell proliferation after lung injury.
    The European respiratory journal, 2010, Volume: 36, Issue:1

    Topics: Animals; Bronchioles; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen Type I; Female; F

2010
Cell type-specific expression of adenomatous polyposis coli in lung development, injury, and repair.
    Developmental dynamics : an official publication of the American Association of Anatomists, 2010, Volume: 239, Issue:8

    Topics: Adenomatous Polyposis Coli Protein; Gene Expression Regulation; Lung; Lung Injury; Naphthalenes; Reg

2010
Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury.
    Respiratory research, 2011, Jun-10, Volume: 12

    Topics: Aged; Analysis of Variance; Animals; beta-Galactosidase; Cell Line, Tumor; Cell Proliferation; Cellu

2011
Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury.
    The Journal of clinical investigation, 2011, Volume: 121, Issue:11

    Topics: Animals; beta Catenin; Cell Differentiation; Epithelial Cells; Epithelial-Mesenchymal Transition; Fi

2011
Cell proliferation contributes to PNEC hyperplasia after acute airway injury.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 1

    Topics: Acute Disease; Animals; Calcitonin Gene-Related Peptide; Cell Division; Epithelium; Histocytochemist

1997