naltrindole and Trichomonas-Vaginitis

naltrindole has been researched along with Trichomonas-Vaginitis* in 1 studies

Other Studies

1 other study(ies) available for naltrindole and Trichomonas-Vaginitis

Article	Year
Investigation of 7-benzylidenenaltrexone derivatives as a novel structural antitrichomonal lead compound. Bioorganic & medicinal chemistry letters, 2015, Nov-01, Volume: 25, Issue:21 We evaluated antitrichomonal effects of δ opioid receptor (DOR) agonists and antagonists. Although all the agonists were inactive, the DOR antagonists BNTX (2a) and its derivatives 2b-d showed antitrichomonal activity with MIC of 20-40 μM. In addition, the development of a more effective synthetic method for the BNTX derivatives was achieved by using the Knoevenagel condensation. Topics: Antitrichomonal Agents; Benzylidene Compounds; Dose-Response Relationship, Drug; Female; Humans; Molecular Structure; Naltrexone; Receptors, Opioid, delta; Structure-Activity Relationship; Trichomonas Vaginitis	2015

Article

Year

Investigation of 7-benzylidenenaltrexone derivatives as a novel structural antitrichomonal lead compound.

Bioorganic & medicinal chemistry letters, 2015, Nov-01, Volume: 25, Issue:21

We evaluated antitrichomonal effects of δ opioid receptor (DOR) agonists and antagonists. Although all the agonists were inactive, the DOR antagonists BNTX (2a) and its derivatives 2b-d showed antitrichomonal activity with MIC of 20-40 μM. In addition, the development of a more effective synthetic method for the BNTX derivatives was achieved by using the Knoevenagel condensation.

Topics: Antitrichomonal Agents; Benzylidene Compounds; Dose-Response Relationship, Drug; Female; Humans; Molecular Structure; Naltrexone; Receptors, Opioid, delta; Structure-Activity Relationship; Trichomonas Vaginitis

2015