naltrexone and Postoperative Complications

naltrexone has been researched along with Postoperative Complications in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.25)18.2507
2000's16 (50.00)29.6817
2010's11 (34.38)24.3611
2020's3 (9.38)2.80

Authors

AuthorsStudies
Atchison, L; Beavers, J; Dennis, B; Guillamondegui, O; Medvecz, A; Orton, L; Smith, MC1
Farhadi, HF; Gifford, CS; McGahan, BG; Minnema, AJ; Miracle, SD; Murphy, CV; Vazquez, DE; Weaver, TE1
Chamie, K; Faiena, I; Golla, V; Johnson, DC; Lec, PM; Lee, C; Lenis, AT; Rahman, S1
Blackney, KA; Edwards, DA; Kamdar, NV; Liu, CA1
Amini, A; Asadi, S; Farbood, A; Zand, F1
Rodriguez, RW1
Chen, R; Guo, R; Li, H; Lin, S; Liu, M; You, C; Zheng, J1
Carvalho, B; Nathan, E; Ng, L; Paech, M; Sia, A; Sng, B1
Kraft, MD1
Becker, G; Blum, HE1
Delaney, CP; Stulberg, JJ; Zeinali, F1
Frost, EA1
Lux, EA1
Baker, DE1
Ladanyi, A; Moss, J; Temkin, SM1
Cabañero, D; Campillo, A; García-Nogales, P; Puig, MM; Romero, A1
Bührer, C; Degenhardt, P; Garten, L1
Carpenito, J; Chun, HK; Randazzo, B; Schulman, S; Stambler, N; Tzanis, E; Yu, CS1
Gardner, AI; Hennessy, B; Sadleir, PH1
Magnuson, B; Thompson, M1
Kurz, A; Sessler, DI1
Sinatra, RS1
Carter, S1
Saclarides, TJ1
Dehaven-Hudkins, DL; Fukuda, H; Hicks, GA; Mantyh, CR; Pappas, TN; Suenaga, K; Takahashi, T; Tsuchida, D1
Jackson, KC; Neyens, R1
Conzen, PF; Reichle, FM1
Camu, F; Franck, P; Moerman, I1
Chehade, J; Duffy, L; Gajraj, N; Johnson, ER; Joshi, GP; Wesevich, J1
Carrigan, KA; Lysle, DT; Nelson, CJ1
Bailey, SL; Faut-Callahan, M; Graves, J; Paice, JA; Pellegrini, JE; Shott, S1
Moss, J; Yuan, CS1

Reviews

9 review(s) available for naltrexone and Postoperative Complications

ArticleYear
Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus.
    Lancet (London, England), 2009, Apr-04, Volume: 373, Issue:9670

    Topics: Analgesics, Opioid; Blood-Brain Barrier; Drug Approval; Europe; Humans; Ileus; Myocardial Infarction; Naltrexone; Narcotic Antagonists; Patient Selection; Piperidines; Postoperative Complications; Quaternary Ammonium Compounds; Research Design; Safety; United States; United States Food and Drug Administration

2009
Pharmacological management of postoperative ileus.
    Canadian journal of surgery. Journal canadien de chirurgie, 2009, Volume: 52, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Bisacodyl; Cathartics; Cisapride; Dihydroergotamine; Humans; Ileus; Inflammation; Naltrexone; Neostigmine; Parasympathomimetics; Piperidines; Postoperative Complications; Propranolol; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Serotonin Receptor Agonists

2009
Methylnaltrexone bromide: new drug for the treatment of opioid-induced bowel dysfunction.
    Reviews in gastroenterological disorders, 2009,Summer, Volume: 9, Issue:3

    Topics: Analgesics, Opioid; Clinical Trials as Topic; Constipation; Dose-Response Relationship, Drug; Drug Interactions; Gastrointestinal Transit; Half-Life; Humans; Infusions, Intravenous; Infusions, Subcutaneous; Laxatives; Naltrexone; Narcotic Antagonists; Postoperative Complications; Quaternary Ammonium Compounds

2009
Opioid-induced bowel dysfunction: pathophysiology and potential new therapies.
    Drugs, 2003, Volume: 63, Issue:7

    Topics: Constipation; Digestive System; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Intestinal Obstruction; Naltrexone; Narcotic Antagonists; Narcotics; Postoperative Complications; Quaternary Ammonium Compounds; Receptors, Opioid; Water-Electrolyte Balance

2003
Peripherally acting mu-opioid-receptor antagonists and the connection between postoperative ileus and pain management: The anesthesiologist's view and beyond.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2006, Volume: 21, Issue:2A Suppl

    Topics: Analgesia; Analgesics, Opioid; Anesthesia; Anesthesiology; Anti-Inflammatory Agents, Non-Steroidal; Attitude of Health Personnel; Blood-Brain Barrier; Clinical Trials, Phase III as Topic; Humans; Ileus; Length of Stay; Naltrexone; Narcotic Antagonists; Nurse's Role; Outcome Assessment, Health Care; Pain, Postoperative; Patient Satisfaction; Piperidines; Postanesthesia Nursing; Postoperative Care; Postoperative Complications; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Risk Factors

2006
The surgical team and outcomes management: focus on postoperative ileus.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2006, Volume: 21, Issue:2A Suppl

    Topics: Analgesics, Opioid; Causality; Cost of Illness; Hospital Costs; Humans; Ileus; Incidence; Laparotomy; Length of Stay; Naltrexone; Narcotic Antagonists; Nurse's Role; Outcome Assessment, Health Care; Pain, Postoperative; Patient Care Team; Patient Satisfaction; Piperidines; Postanesthesia Nursing; Postoperative Care; Postoperative Complications; Professional Role; Quaternary Ammonium Compounds; Time Factors; Total Quality Management

2006
Current choices--good or bad--for the proactive management of postoperative ileus: A surgeon's view.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2006, Volume: 21, Issue:2A Suppl

    Topics: Analgesia, Epidural; Analgesics, Opioid; Attitude of Health Personnel; Choice Behavior; Enteral Nutrition; Evidence-Based Medicine; General Surgery; Humans; Ileus; Intubation, Gastrointestinal; Laparoscopy; Laparotomy; Length of Stay; Naltrexone; Narcotic Antagonists; Outcome Assessment, Health Care; Patient Care Team; Patient Selection; Piperidines; Postoperative Care; Postoperative Complications; Practice Guidelines as Topic; Quaternary Ammonium Compounds; Risk Factors

2006
Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus.
    Journal of pain & palliative care pharmacotherapy, 2007, Volume: 21, Issue:2

    Topics: Analgesics, Opioid; Gastrointestinal Transit; Humans; Ileus; Intestinal Diseases; Naltrexone; Narcotic Antagonists; Piperidines; Postoperative Complications; Quaternary Ammonium Compounds

2007
Methylnaltrexone, a new peripheral mu-receptor antagonist for the prevention and treatment of opioid-induced extracerebral side effects.
    Current opinion in investigational drugs (London, England : 2000), 2008, Volume: 9, Issue:1

    Topics: Analgesics, Opioid; Gastrointestinal Motility; Humans; Ileus; Naltrexone; Postoperative Complications; Postoperative Nausea and Vomiting; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Urinary Retention

2008

Trials

7 trial(s) available for naltrexone and Postoperative Complications

ArticleYear
Design and feasibility of a double-blind, randomized trial of peri-operative methylnaltrexone for postoperative ileus prevention after adult spinal arthrodesis.
    Contemporary clinical trials, 2022, Volume: 112

    Topics: Adult; Arthrodesis; Feasibility Studies; Humans; Ileus; Male; Naltrexone; Postoperative Complications; Quaternary Ammonium Compounds; Retrospective Studies

2022
The effect of methylnaltrexone on the side effects of intrathecal morphine after orthopedic surgery under spinal anesthesia.
    Pain practice : the official journal of World Institute of Pain, 2015, Volume: 15, Issue:4

    Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Naltrexone; Narcotic Antagonists; Orthopedic Procedures; Pain, Postoperative; Postoperative Complications; Quaternary Ammonium Compounds; Young Adult

2015
Methylnaltrexone to prevent intrathecal morphine-induced pruritus after Caesarean delivery: a multicentre, randomized clinical trial.
    British journal of anaesthesia, 2015, Volume: 114, Issue:3

    Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Australia; Cesarean Section; Female; Humans; Middle Aged; Morphine; Naltrexone; Narcotic Antagonists; Postoperative Complications; Pregnancy; Pruritus; Quaternary Ammonium Compounds; Singapore; Treatment Outcome; United States; Young Adult

2015
Safety and efficacy of methylnaltrexone in shortening the duration of postoperative ileus following segmental colectomy: results of two randomized, placebo-controlled phase 3 trials.
    Diseases of the colon and rectum, 2011, Volume: 54, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Colectomy; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Ileus; Injections, Intravenous; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Postoperative Complications; Quaternary Ammonium Compounds; Retrospective Studies; Treatment Outcome; Young Adult

2011
Evaluation of methylnaltrexone for the reduction of postoperative vomiting and nausea incidences.
    Acta anaesthesiologica Belgica, 1995, Volume: 46, Issue:3-4

    Topics: Adult; Antiemetics; Double-Blind Method; Female; Humans; Middle Aged; Naltrexone; Narcotic Antagonists; Nausea; Postoperative Complications; Prospective Studies; Quaternary Ammonium Compounds; Vomiting

1995
Effects of prophylactic nalmefene on the incidence of morphine-related side effects in patients receiving intravenous patient-controlled analgesia.
    Anesthesiology, 1999, Volume: 90, Issue:4

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Humans; Middle Aged; Morphine; Naltrexone; Narcotic Antagonists; Nausea; Postoperative Complications; Pruritus; Vomiting

1999
The impact of nalmefene on side effects due to intrathecal morphine at cesarean section.
    AANA journal, 2001, Volume: 69, Issue:3

    Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Naltrexone; Narcotic Antagonists; Pain, Postoperative; Postoperative Complications; Postoperative Nausea and Vomiting; Pregnancy; Pruritus; Statistics, Nonparametric; Survival Analysis; Time Factors

2001

Other Studies

16 other study(ies) available for naltrexone and Postoperative Complications

ArticleYear
The Efficacy and Safety of Methylnaltrexone for the Treatment of Postoperative Ileus.
    The American surgeon, 2022, Volume: 88, Issue:3

    Topics: Female; Humans; Ileus; Intestinal Perforation; Intubation, Gastrointestinal; Length of Stay; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Parenteral Nutrition; Postoperative Complications; Quaternary Ammonium Compounds; Retrospective Studies; Time Factors; Treatment Outcome

2022
The association between N-methylnaltrexone, a peripherally acting mu-opioid receptor antagonist, and clinical outcomes in patients undergoing robotic-assisted radical cystectomy.
    World journal of urology, 2020, Volume: 38, Issue:12

    Topics: Aged; Cystectomy; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Postoperative Complications; Postoperative Period; Quaternary Ammonium Compounds; Retrospective Studies; Robotic Surgical Procedures; Treatment Outcome; Urinary Bladder Neoplasms

2020
Methylnaltrexone-Associated Bowel Perforation in Postoperative Opioid-Induced Constipation and Ogilvie Syndrome: A Case Report.
    A&A practice, 2019, Jan-15, Volume: 12, Issue:2

    Topics: Analgesics, Opioid; Colonic Pseudo-Obstruction; Constipation; Decompression, Surgical; Humans; Hydromorphone; Intestinal Perforation; Low Back Pain; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Postoperative Complications; Quaternary Ammonium Compounds; Spinal Stenosis

2019
Off-label uses of alvimopan and methylnaltrexone.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2014, Sep-01, Volume: 71, Issue:17

    Topics: Analgesics, Opioid; Constipation; Gastrointestinal Agents; Humans; Ileus; Naltrexone; Narcotic Antagonists; Off-Label Use; Piperidines; Postoperative Complications; Quaternary Ammonium Compounds

2014
Neuroprotection of nalmefene for postoperative patients with spontaneous intracerebral hemorrhage.
    The International journal of neuroscience, 2015, Volume: 125, Issue:12

    Topics: Adult; Aged; Cerebral Hemorrhage; China; Female; Humans; Male; Middle Aged; Naltrexone; Neuroimaging; Neuroprotective Agents; Postoperative Complications; Retrospective Studies; Severity of Illness Index; Stroke; Treatment Outcome

2015
Methylnaltrexone, a new peripherally acting mu-opioid receptor antagonist being evaluated for the treatment of postoperative ileus.
    Expert opinion on investigational drugs, 2008, Volume: 17, Issue:9

    Topics: Animals; Clinical Trials as Topic; Drug Evaluation; Humans; Ileus; Naltrexone; Postoperative Complications; Quaternary Ammonium Compounds; Receptors, Opioid, mu

2008
Preventing paralytic ileus: can the anesthesiologist help.
    Middle East journal of anaesthesiology, 2009, Volume: 20, Issue:2

    Topics: Analgesics, Opioid; Anesthetics; Gastrointestinal Agents; Humans; Intestinal Pseudo-Obstruction; Intubation, Gastrointestinal; Naltrexone; Piperidines; Postoperative Complications; Preoperative Care; Quaternary Ammonium Compounds

2009
[Successful treatment of treatment-resistant opioid-induced constipation in a patient with incomplete paraplegia with methylnaltrexone].
    Schmerz (Berlin, Germany), 2009, Volume: 23, Issue:5

    Topics: Aged; Cervical Vertebrae; Constipation; Fecal Impaction; Humans; Injections, Subcutaneous; Male; Naltrexone; Narcotic Antagonists; Narcotics; Paraplegia; Postoperative Complications; Quaternary Ammonium Compounds; Spinal Cord Compression

2009
Subcutaneous methylnaltrexone to restore postoperative bowel function in a long-term opiate user.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2010, Volume: 20, Issue:2

    Topics: Analgesics, Opioid; Female; Heroin Dependence; Humans; Ileus; Injections, Subcutaneous; Middle Aged; Naltrexone; Narcotic Antagonists; Postoperative Complications; Quaternary Ammonium Compounds

2010
Delayed postoperative latent pain sensitization revealed by the systemic administration of opioid antagonists in mice.
    European journal of pharmacology, 2011, Apr-25, Volume: 657, Issue:1-3

    Topics: Animals; Dizocilpine Maleate; Dynorphins; Hyperalgesia; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Threshold; Piperidines; Postoperative Complications; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Remifentanil; Spinal Cord

2011
Resolution of opioid-induced postoperative ileus in a newborn infant after methylnaltrexone.
    Journal of pediatric surgery, 2011, Volume: 46, Issue:3

    Topics: Aortic Arch Syndromes; Coronary Disease; Extracorporeal Membrane Oxygenation; Fatal Outcome; Female; Fentanyl; Humans; Infant, Newborn; Intestinal Pseudo-Obstruction; Naltrexone; Narcotic Antagonists; Narcotics; Pain, Postoperative; Postoperative Complications; Quaternary Ammonium Compounds; Remission Induction

2011
Adverse events in the removal of naltrexone implants.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:5

    Topics: Adolescent; Adult; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthetics, General; Anesthetics, Local; Device Removal; Female; Humans; Incidence; Infections; Infusion Pumps, Implantable; Length of Stay; Male; Middle Aged; Morphine; Naltrexone; Narcotic Antagonists; Pain, Postoperative; Postoperative Complications; Retrospective Studies; Young Adult

2011
Management of postoperative ileus.
    Orthopedics, 2012, Volume: 35, Issue:3

    Topics: Combined Modality Therapy; Exercise Therapy; Gastrointestinal Agents; Humans; Ileus; Naltrexone; Narcotic Antagonists; Piperidines; Postoperative Complications; Quaternary Ammonium Compounds

2012
The selective mu opioid receptor antagonist, alvimopan, improves delayed GI transit of postoperative ileus in rats.
    Brain research, 2006, Aug-02, Volume: 1102, Issue:1

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Transit; Ileus; Laparotomy; Male; Naltrexone; Narcotic Antagonists; Piperidines; Postoperative Complications; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley

2006
Naltrexone administration attenuates surgery-induced immune alterations in rats.
    The Journal of surgical research, 2000, Volume: 94, Issue:2

    Topics: Abdomen; Animals; B-Lymphocytes; Bacterial Toxins; Concanavalin A; Enterotoxins; Humans; Interferon-gamma; Killer Cells, Natural; Lymphocyte Activation; Male; Naltrexone; Peritoneal Cavity; Postoperative Complications; Rats; Rats, Inbred Lew; Spleen; Superantigens; Surgical Procedures, Operative; T-Lymphocytes

2000
Selective postoperative inhibition of gastrointestinal opioid receptors.
    The New England journal of medicine, 2002, Feb-07, Volume: 346, Issue:6

    Topics: Humans; Intestinal Obstruction; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Postoperative Complications; Postoperative Nausea and Vomiting; Quaternary Ammonium Compounds

2002