naltrexone and Muscle Contraction

naltrexone has been researched along with Muscle Contraction in 87 studies

Research

Studies (87)

Timeframe	Studies, this research(%)	All Research%
pre-1990	32 (36.78)	18.7374
1990's	33 (37.93)	18.2507
2000's	16 (18.39)	29.6817
2010's	5 (5.75)	24.3611
2020's	1 (1.15)	2.80

Authors

Authors	Studies
Lipkowski, AW; Portoghese, AS; Takemori, AE	1
Fries, DS; Larson, DL; Portoghese, PS; Sayre, LM; Takemori, AE	1
Alreja, BD; Larson, DL; Portoghese, PS	1
Carling, RW; Kobylecki, RJ; Lane, AC; Lord, JA; Smith, CF	1
Ananthan, S; Bilsky, EJ; Carter, RL; Davis, P; Dersch, CM; Kezar, HS; Porreca, F; Rice, KC; Rothman, RB; Saini, SK; Wells, JL; Xu, H	1
Ananthan, S; Bartlett, JL; Bilsky, EJ; Davis, P; Dersch, CM; Khare, NK; Porreca, F; Rothman, RB; Saini, SK; Seitz, LE	1
Cajander, P; Cock, C; Magnuson, A; Omari, T; Savilampi, J; Scheinin, M	1
Nelson, DE; Nickles, A; Su, X	1
Akbarali, HI; David, BG; Dewey, WL; Scoggins, KL; Selley, DE; Stevens, DL; Williams, DA; Yuan, Y; Zaidi, SA; Zhang, Y; Zheng, Y	1
Cami-Kobeci, G; Fichna, J; Husbands, S; Jarmuż, A; Wasilewski, A; Zielińska, M	1
Kitamura, T; Ogawa, M; Yamada, Y	1
Goyal, R; Kumar, K; Mohan, A; Mudgal, A; Pasha, S	1
Baroffio, M; Brusasco, V; Crimi, E; Rehder, K	1
Akao, Y; Arakawa, S; Fujisawa, M; Goto, K; Gotoh, A; Kamidono, S; Okada, H; Sasaki, H; Sengoku, A; Shirakawa, T	1
Ananthan, S; Davis, P; Dersch, CM; Kezar, HS; Khare, NK; Porreca, F; Rothman, RB; Saini, SK	1
Coupar, IM; Gray, AC; White, PJ	1
Chang, JP; Chang, KJ; Gengo, PJ; Holt, JD; O'Neill, SJ; Pendergast, W; Watson, MJ; Wei, K	1
Boscan, PL; van Hoogmoed, LM	1
McCurdy, CR; Nieto, MJ; Smith, GH; Sufka, KJ; Warnick, JE	1
Ahmadi, SH; Dehghani, M; Dehpour, AR; Ebrahimi, F; Hajrasouliha, AR; Sadeghipour, H; Tavakoli, S	1
Hatori, Y; Horie, S; Kitajima, M; Matsumoto, K; Misawa, K; Murayama, T; Takayama, H; Tashima, K; Wongseripipatana, S	1
Beattie, DT; Cheruvu, M; Johnson-Rabidoux, S; Kaufman, E; Mai, N; O'Keefe, M; Peterson, C; Vickery, R	1
Chen, TY; Gomery, P; Israel, R; Rosow, CE; Stambler, N; Stefanovich, P	1
Chavkin, C; Goldstein, A	2
Berzétei, IP; Kurgyis, J; Rónai, AZ	1
Kosterlitz, HW; Lord, JA; Paterson, SJ; Waterfield, AA	1
Bajusz, S; Berzétei, IP; Rónai, AZ; Székely, JI	1
Chavkin, C; Cox, BM	1
Fischli, W; Goldstein, A; James, IF	1
Herling, S; Medzihradsky, F; Merz, H; Valentino, RJ; Woods, JH	1
Larson, DL; Portoghese, PS; Takemori, AE	1
Bohus, B; Csontos, KM; de Rotte, GA; de Wied, D; Gispen, WH; Greven, HM; Nijkamp, FP; Opmeer, FA; van Ree, JM; van Wimersma Greidanus, TB; Witter, A	1
Burks, TF; Porreca, F	1
Maas, CL	1
Erez, M; Portoghese, PS; Takemori, AE	1
Alsasua, A; Martín, MI; Parra, L; Pérez-Vizcaíno, F; Tamargo, J	1
Coupar, IM; Hancock, DL	1
Foss, JF; Moss, J; Yuan, CS	1
Angel, F; Baumann, R; Chamouard, P; Meyer, C; Rohr, S	1
Brent, PJ; Cantarell, PA; Chahl, LA; Kavanagh, C	1
Kishioka, S; Masuda, Y; Miyamoto, Y; Ozaki, M; Yamamoto, H	1
Brune, K; Geisslinger, G; Schmidt, N	1
Froetschel, MA; Kil, SJ	1
Amico, MC; Morrone, LA; Romanelli, L; Valeri, P	1
Anacardio, R; Attila, M; Bryant, SD; Capasso, A; Guerrini, R; Lazarus, LH; Salvadori, S; Sorrentino, L	1
Khan, S; Smith, ME	1
Bymaster, FP; Mitch, CH; Olesen, PH; Sauerberg, P; Shannon, HE; Sheardown, MJ; Suzdak, PD; Swedberg, MD; Ward, JS	1
Fang, X; Larson, DL; Portoghese, PS	1
Higashiyama, K; Kamei, J; Kubo, H; Li, J; Nagase, H; Ohmiya, S; Ohsawa, M; Takahashi, H; Xiao, P	1
Fang, X; Kshirsagar, TA; Portoghese, PS	1
Ananthan, S; Carter, RL; Clayton, SD; Davis, P; Johnson, CA; Porreca, F; Rice, KC; Rothman, RB; Xu, H	1
Kizawa, Y; Koike, K; Okayasu, A; Suzuki, T; Takayanagi, I	1
Gray, AM; Sewell, RD; Spencer, PS	1
Ohkawa, S; Portoghese, PS	1
Coop, A; Davis, P; Dersch, C; Jacobson, AE; Partilla, J; Porreca, F; Rice, KC; Rothman, RB	1
Fischer, A; Undem, BJ	1
Amico, MC; Mattioli, F; Morrone, LA; Romanelli, L; Valeri, P	1
Broom, DC; Coop, A; Guo, L; Husbands, SM; Lewis, JW; Traynor, JR; Woods, JH	1
Brown, DR; Poonyachoti, S; Portoghese, PS	1
Kieffer, BL; Maldonado, R; Matthes, HW; Melchiorri, P; Negri, L; Severini, C	1
Ferguson, DM; Jones, RM; Metzger, TG; Portoghese, PS; Sharma, SK	1
Craviso, GL; Gascon, P; Musacchio, JM; Puig, MM	1
Berti, F; Bruno, F; Omini, C; Racagni, G	1
Foldes, FF; Knoll, J; Rich, J; Vizi, ES	1
Berggren, A; Rubenson, A; Sillén, U	1
Berzetei-Gurske, IP; Toll, L	1
Klein, P; Nelson, WL; Portoghese, PS; Sultana, M; Takemori, AE	1
Kastin, AJ; Kersh, D; Wyatt, A; Zadina, JE	1
Kaneto, H; Kawasaki, K; Kobayashi, Y; Maeda, M; Shimokawa, K; Taguchi, T; Takahashi, M; Tokuyama, S; Watanabe, J; Yamamoto, Y	1
Bilotta, JM; Brackeen, MF; Feldman, PL; James, MK; Leighton, HJ; Schuster, SV	1
Garzon-Aburbeh, A; Lin, CE; Nagase, H; Portoghese, PS; Takemori, AE	1
Kaneto, H; Takahashi, M; Watanabe, J	1
Dixon, DM; Traynor, JR	1
Ayres, EA; Burks, TF; Davis, P	1
Cherubini, E; North, RA; Tokimasa, T	1
Portoghese, PS; Sultana, M; Takemori, AE	1
Leander, JD	1
Hayes, AG; Sheehan, MJ; Tyers, MB	1
Dray, A; Nunan, L; Wire, W	1
Corbett, AD; Kostelitz, HW; McKnight, AT; Paterson, SJ; Robson, LE	1
James, DW; LoPresti, D; Ward, SJ	1
Larson, DL; Portoghese, PS; Ronsisvalle, G; Takemori, AE	1
Hynes, MD; Leander, JD; Reel, JK; Zimmerman, DM	1
Portoghese, PS; Schoenecker, JW; Takemori, AE	1
Corbett, AD; Kosterlitz, HW; Traynor, JR	1
Birch, PJ; Hayes, AG	1

Trials

2 trial(s) available for naltrexone and Muscle Contraction

Article	Year
Effects of remifentanil on pharyngeal swallowing and esophageal motility: no impact of different bolus volumes and partial antagonism by methylnaltrexone. American journal of physiology. Gastrointestinal and liver physiology, 2021, 10-01, Volume: 321, Issue:4 Topics: Adult; Analgesics, Opioid; Deglutition; Drug Antagonism; Esophagus; Female; Healthy Volunteers; Humans; Injections, Intravenous; Male; Muscle Contraction; Muscle Relaxation; Naltrexone; Narcotic Antagonists; Pharynx; Quaternary Ammonium Compounds; Remifentanil	2021
Reversal of opioid-induced bladder dysfunction by intravenous naloxone and methylnaltrexone. Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:1 Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Humans; Infusions, Intravenous; Male; Middle Aged; Miosis; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Remifentanil; Treatment Outcome; Urinary Bladder; Urinary Retention; Urination	2007

Article

Year

Effects of remifentanil on pharyngeal swallowing and esophageal motility: no impact of different bolus volumes and partial antagonism by methylnaltrexone.

American journal of physiology. Gastrointestinal and liver physiology, 2021, 10-01, Volume: 321, Issue:4

Topics: Adult; Analgesics, Opioid; Deglutition; Drug Antagonism; Esophagus; Female; Healthy Volunteers; Humans; Injections, Intravenous; Male; Muscle Contraction; Muscle Relaxation; Naltrexone; Narcotic Antagonists; Pharynx; Quaternary Ammonium Compounds; Remifentanil

2021

Reversal of opioid-induced bladder dysfunction by intravenous naloxone and methylnaltrexone.

Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:1

Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Humans; Infusions, Intravenous; Male; Middle Aged; Miosis; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Remifentanil; Treatment Outcome; Urinary Bladder; Urinary Retention; Urination

2007

Other Studies

85 other study(ies) available for naltrexone and Muscle Contraction

Article	Year
Bimorphinans as highly selective, potent kappa opioid receptor antagonists. Journal of medicinal chemistry, 1987, Volume: 30, Issue:2 Topics: Animals; Guinea Pigs; Male; Mice; Morphinans; Muscle Contraction; Muscle, Smooth; Receptors, Opioid; Receptors, Opioid, kappa; Structure-Activity Relationship	1987
A novel opioid receptor site directed alkylating agent with irreversible narcotic antagonistic and reversible agonistic activities. Journal of medicinal chemistry, 1980, Volume: 23, Issue:3 Topics: Alkylating Agents; Animals; Guinea Pigs; In Vitro Techniques; Morphinans; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Narcotics; Oxymorphone; Receptors, Opioid	1980
Allylprodine analogues as receptor probes. Evidence that phenolic and nonphenolic ligands interact with different subsites on identical opioid receptors. Journal of medicinal chemistry, 1981, Volume: 24, Issue:7 Topics: Animals; Chemical Phenomena; Chemistry, Physical; Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Narcotic Antagonists; Phenols; Piperidines; Reaction Time; Receptors, Opioid; Structure-Activity Relationship	1981
Common anionic receptor site hypothesis: its relevance to the antagonist action of naloxone. Journal of medicinal chemistry, 1982, Volume: 25, Issue:2 Topics: Animals; Anions; Chemical Phenomena; Chemistry; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotics; Rats; Receptors, Opioid	1982
Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans. Journal of medicinal chemistry, 1999, Sep-09, Volume: 42, Issue:18 Topics: Analgesics; Animals; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Mice, Inbred Strains; Morphinans; Morphine; Muscle Contraction; Naltrexone; Protein Binding; Rats; Receptors, Opioid; Vas Deferens	1999
Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone]. Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6 Topics: Analgesics; Animals; Binding Sites; Brain; Drug Tolerance; Electric Stimulation; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Morphinans; Muscle Contraction; Muscle, Smooth; Naloxone; Oxymorphone; Pyridines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens	2004
Role of the endogenous opioid system in modulation of urinary bladder activity by spinal nerve stimulation. American journal of physiology. Renal physiology, 2013, Jul-01, Volume: 305, Issue:1 Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Morphine; Muscle Contraction; Naltrexone; Narcotic Antagonists; Neural Inhibition; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spinal Nerves; Time Factors; Urinary Bladder; Urination	2013
6β-N-Heterocyclic Substituted Naltrexamine Derivative BNAP: A Peripherally Selective Mixed MOR/KOR Ligand. ACS chemical neuroscience, 2016, 08-17, Volume: 7, Issue:8 Topics: Animals; Binding, Competitive; CHO Cells; Cricetulus; Disease Models, Animal; Gastrointestinal Motility; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Male; Mice; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth; Naltrexone; Neurons; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship	2016
Methyl-orvinol-Dual activity opioid receptor ligand inhibits gastrointestinal transit and alleviates abdominal pain in the mouse models mimicking diarrhea-predominant irritable bowel syndrome. Pharmacological reports : PR, 2017, Volume: 69, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Abdominal Pain; Analgesics; Analgesics, Opioid; Animals; Colon; Diarrhea; Disease Models, Animal; Gastrointestinal Motility; Gastrointestinal Transit; Irritable Bowel Syndrome; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Receptors, Opioid; Thebaine	2017
The individual and combined effects of U50,488, and flurbiprofen axetil on visceral pain in conscious rats. Anesthesia and analgesia, 2009, Volume: 108, Issue:6 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Abdominal Muscles; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Catheterization; Dose-Response Relationship, Drug; Drug Synergism; Flurbiprofen; Male; Muscle Contraction; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Rectum	2009
YFa and analogs: investigation of opioid receptors in smooth muscle contraction. World journal of gastroenterology, 2011, Oct-28, Volume: 17, Issue:40 Topics: Acetylcholine; Analgesics, Opioid; Animals; Cholinergic Agonists; Dynorphins; Enkephalin, Methionine; Guinea Pigs; Ileum; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Oligopeptides; Receptors, Opioid; Vas Deferens	2011
Effects of κ- and μ-opioid agonists on cholinergic neurotransmission and contraction in isolated bovine trachealis. Respiratory physiology & neurobiology, 2013, Jan-15, Volume: 185, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Atropine; Cattle; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; In Vitro Techniques; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Naltrexone; Narcotic Antagonists; Pilocarpine; Receptors, Opioid, kappa; Receptors, Opioid, mu; Trachea; Tritium	2013
Inhibition of urinary bladder motility by a spinal action of U-50488H in rats. The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:12 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Area Under Curve; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intravenous; Injections, Spinal; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Naltrexone; Pons; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reserpine; Serotonin Antagonists; Stress, Mechanical; Urinary Bladder; Urination; Yohimbine	2002
Synthesis, opioid receptor binding, and functional activity of 5'-substituted 17-cyclopropylmethylpyrido[2',3':6,7]morphinans. Bioorganic & medicinal chemistry letters, 2003, Feb-10, Volume: 13, Issue:3 Topics: Animals; Brain Chemistry; Guanidines; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Male; Morphinans; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Pyridines; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship; Vas Deferens	2003
Characterisation of opioid receptors involved in modulating circular and longitudinal muscle contraction in the rat ileum. British journal of pharmacology, 2005, Volume: 144, Issue:5 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enteric Nervous System; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu	2005
DPI-221 [4-((alpha-s)-alpha-((2s,5r)-2,5-dimethyl-4-(3-fluorobenzyl)-1-piperazinyl)benzyl)-N,N-diethylbenzamide]: a novel nonpeptide delta receptor agonist producing increased micturition interval in normal rats. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:2 Topics: Animals; Benzhydryl Compounds; Blood Gas Analysis; Carbachol; Convulsants; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Naltrexone; Narcotic Antagonists; Pain Measurement; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Urinary Bladder; Urination; Vas Deferens	2005
In vitro evaluation of the effect of the opioid antagonist N-methylnaltrexone on motility of the equine jejunum and pelvic flexure. Equine veterinary journal, 2005, Volume: 37, Issue:4 Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Gastrointestinal Motility; Horses; Jejunum; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Pelvis; Quaternary Ammonium Compounds; Tissue Culture Techniques	2005
Antinociceptive profile of salvinorin A, a structurally unique kappa opioid receptor agonist. Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:1 Topics: Acetic Acid; Analgesics; Animals; Diterpenes; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Hot Temperature; Male; Mice; Muscle Contraction; Naltrexone; Nociceptors; Pain Measurement; Plant Leaves; Psychotropic Drugs; Reaction Time; Receptors, Opioid, kappa	2006
Involvement of endogenous opioid peptides and nitric oxide in the blunted chronotropic and inotropic responses to beta-adrenergic stimulation in cirrhotic rats. Fundamental & clinical pharmacology, 2006, Volume: 20, Issue:5 Topics: Adrenergic beta-Agonists; Animals; Bile Ducts; Enzyme Inhibitors; Guanidines; Heart Atria; In Vitro Techniques; Isoproterenol; Ligation; Liver Cirrhosis, Biliary; Male; Muscle Contraction; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Opioid Peptides; Papillary Muscles; Rats; Rats, Sprague-Dawley	2006
Involvement of mu-opioid receptors in antinociception and inhibition of gastrointestinal transit induced by 7-hydroxymitragynine, isolated from Thai herbal medicine Mitragyna speciosa. European journal of pharmacology, 2006, Nov-07, Volume: 549, Issue:1-3 Topics: Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Gastrointestinal Transit; Guinea Pigs; Herbal Medicine; Ileum; Male; Mice; Mitragyna; Molecular Structure; Morphine; Muscle Contraction; Naltrexone; Narcotic Antagonists; Narcotics; Pain; Pain Measurement; Receptors, Opioid, mu; Secologanin Tryptamine Alkaloids; Thailand; Vas Deferens	2006
The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone. Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 375, Issue:3 Topics: Analgesics, Opioid; Animals; Benzeneacetamides; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Naltrexone; Narcotic Antagonists; Oligopeptides; Piperidines; Pyrrolidines; Quaternary Ammonium Compounds; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Proteins; Transfection	2007
Opioid receptor reserve in normal and morphine-tolerant guinea pig ileum myenteric plexus. Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:22 Topics: Animals; Guinea Pigs; Humans; Male; Morphine Dependence; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naltrexone; Receptors, Opioid	1984
Opioid effects in developing rat vas deferens. Cellular and molecular neurobiology, 1981, Volume: 1, Issue:4 Topics: Animals; Electric Stimulation; Endorphins; In Vitro Techniques; Male; Muscle Contraction; Naltrexone; Rats; Receptors, Opioid; Vas Deferens	1981
Effects of changes in the structure of enkephalins and of narcotic analgesic drugs on their interactions with mu- and delta-receptors. British journal of pharmacology, 1980, Volume: 68, Issue:2 Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Endorphins; Enkephalins; Guinea Pigs; Ligands; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Naltrexone; Receptors, Opioid; Structure-Activity Relationship	1980
The in vitro pharmacology of D-Met2,Pro5-enkephalinamide. The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:8 Topics: Animals; Endorphins; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotics; Nictitating Membrane; Rats; Receptors, Opioid; Vas Deferens	1981
Comparison of dynorphin-selective Kappa receptors in mouse vas deferens and guinea pig ileum. Spare receptor fraction as a determinant of potency. Molecular pharmacology, 1983, Volume: 23, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guinea Pigs; Ileum; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, kappa; Structure-Activity Relationship; Vas Deferens	1983
Opioid receptor selectivity of dynorphin gene products. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:1 Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Naltrexone; Peptide Fragments; Protein Precursors; Receptors, Opioid	1984
Quaternary naltrexone: evidence for the central mediation of discriminative stimulus effects of narcotic agonists and antagonists. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3 Topics: Animals; Brain; Columbidae; Discrimination, Psychological; Etorphine; Macaca mulatta; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid	1981
The irreversible narcotic antagonistic and reversible agonistic properties of the fumaramate methyl ester derivative of naltrexone. European journal of pharmacology, 1981, Apr-09, Volume: 70, Issue:4 Topics: Affinity Labels; Animals; Ileum; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship	1981
Demonstration of a specific dynorphin receptor in guinea pig ileum myenteric plexus. Nature, 1981, Jun-18, Volume: 291, Issue:5816 Topics: Animals; Binding, Competitive; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Guinea Pigs; Ileum; Kinetics; Muscle Contraction; Myenteric Plexus; Naltrexone; Narcotic Antagonists; Narcotics; Nitrogen Mustard Compounds; Peptide Fragments; Receptors, Opioid	1981
Gamma-melanotropin and brain function. Ciba Foundation symposium, 1981, Volume: 81 Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; beta-Endorphin; Biological Assay; Brain; Endorphins; Guinea Pigs; Melanocyte-Stimulating Hormones; Muscle Contraction; Naloxone; Naltrexone; Pituitary Hormones, Anterior; Pro-Opiomelanocortin; Protein Precursors; Rats; Receptors, Opioid	1981
Use of the novel irreversible opiate antagonist, beta-chlornaltrexamine, in the estimation of the normorphine affinity constant in naive and morphine tolerant guinea-pig ilea. Proceedings of the Western Pharmacology Society, 1983, Volume: 26 Topics: Animals; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists	1983
Opiate antagonists stimulate ruminal motility of conscious goats. European journal of pharmacology, 1982, Jan-08, Volume: 77, Issue:1 Topics: Animals; Female; Goats; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Rumen	1982
Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites. Journal of medicinal chemistry, 1982, Volume: 25, Issue:7 Topics: Animals; Chemical Phenomena; Chemistry; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Ligands; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists	1982
mu- and delta-opioid receptor-mediated contractile effects on rat aortic vascular smooth muscle. European journal of pharmacology, 1995, Apr-13, Volume: 277, Issue:1 Topics: Amino Acid Sequence; Analgesics; Analysis of Variance; Animals; Aorta; Benzomorphans; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Molecular Sequence Data; Morphine; Muscle Contraction; Muscle, Smooth, Vascular; Naltrexone; Norepinephrine; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu	1995
Evidence for functional delta-opiate receptors in the rat intestine. The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:10 Topics: Acetylcholine; Animals; Cricetinae; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; In Vitro Techniques; Jejunum; Male; Mice; Muscle Contraction; Muscle, Smooth; Naltrexone; Rats; Rats, Wistar; Receptors, Opioid, delta	1994
Effects of methylnaltrexone on morphine-induced inhibition of contraction in isolated guinea-pig ileum and human intestine. European journal of pharmacology, 1995, Mar-24, Volume: 276, Issue:1-2 Topics: Adult; Aged; Animals; Gastrointestinal Motility; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Intestine, Small; Middle Aged; Morphine; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds	1995
Delta-opioid receptor agonists inhibit neuromuscular transmission in human colon. European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2 Topics: Analgesics; Analgesics, Opioid; Colon; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Gastrointestinal Motility; Humans; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Neuromuscular Junction; Peptide Fragments; Receptors, Opioid, delta; Synaptic Transmission	1994
The kappa-opioid receptor agonist U50,488H induces acute physical dependence in guinea-pigs. European journal of pharmacology, 1993, Sep-14, Volume: 241, Issue:2-3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Behavior, Animal; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine Dependence; Motor Activity; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Pyrrolidines; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Substance-Related Disorders	1993
Participation of opioid receptor types on post-tetanic twitch inhibition in isolated guinea-pig ileal longitudinal muscle. Neuropharmacology, 1994, Volume: 33, Issue:5 Topics: Amino Acid Sequence; Animals; Dynorphins; Electric Stimulation; Enkephalin, Leucine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Molecular Sequence Data; Morphine; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Narcotics; Peptide Fragments; Receptors, Opioid	1994
Opioid receptor agonist potencies of morphine and morphine-6-glucuronide in the guinea-pig ileum. European journal of pharmacology, 1994, Apr-01, Volume: 255, Issue:1-3 Topics: Amino Acid Sequence; Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Molecular Sequence Data; Morphine; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Naltrexone; Peptide Fragments; Peptides; Receptors, Opioid; Receptors, Opioid, mu; Somatostatin	1994
Involvement of opioid peptides from casein on reticular motility and digesta passage in steers. Journal of dairy science, 1994, Volume: 77, Issue:1 Topics: Abomasum; Animals; Caseins; Cattle; Digestion; Endorphins; Gastrointestinal Motility; Hydrolysis; Male; Muscle Contraction; Naltrexone; Reticulum; Solutions	1994
Withdrawal contractures of guinea-pig isolated ileum after acute activation of kappa-opioid receptors. British journal of pharmacology, 1993, Volume: 109, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Nifedipine; Pyrrolidines; Receptors, Opioid, kappa; Substance Withdrawal Syndrome	1993
Opioid receptor selectivity alteration by single residue replacement: synthesis and activity profile of [Dmt1]deltorphin B. European journal of pharmacology, 1996, Apr-29, Volume: 302, Issue:1-3 Topics: Animals; Mice; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Threshold; Rabbits; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu	1996
Actions of beta-endorphin peptides on the contractions of mouse diaphragm muscle. Peptides, 1997, Volume: 18, Issue:1 Topics: Animals; Benzylidene Compounds; beta-Endorphin; Diaphragm; Dipeptides; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Mice; Mice, Inbred C57BL; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neostigmine; Oligopeptides; Peptide Fragments	1997
M1 receptor agonist activity is not a requirement for muscarinic antinociception. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:2 Topics: Analgesics; Animals; Atrial Function; Cell Line; Cricetinae; Guinea Pigs; Heart Atria; Humans; Hydrolysis; In Vitro Techniques; Inositol Phosphates; Male; Mice; Muscarinic Agonists; Muscle Contraction; N-Methylscopolamine; Naltrexone; Rabbits; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Transfection; Vas Deferens	1997
7-spirobenzocyclohexyl derivatives of naltrexone, oxymorphone, and hydromorphone as selective opioid receptor ligands. Journal of medicinal chemistry, 1997, Sep-12, Volume: 40, Issue:19 Topics: Animals; Electric Stimulation; Guinea Pigs; Hydromorphone; In Vitro Techniques; Ligands; Male; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotics; Oxymorphone; Receptors, Opioid, delta; Spiro Compounds; Structure-Activity Relationship	1997
Antinociceptive effects of (+)-matrine in mice. European journal of pharmacology, 1997, Oct-22, Volume: 337, Issue:2-3 Topics: Abdomen; Alkaloids; Analgesics; Animals; Male; Matrines; Mice; Mice, Inbred ICR; Muscle Contraction; Naltrexone; Narcotic Antagonists; Pain Measurement; Quinolizines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tail	1997
14-Desoxy analogues of naltrindole and 7-spiroindanyloxymorphone: the role of the 14-hydroxy group at delta opioid receptors. Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14 Topics: Animals; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Oxymorphone; Receptors, Opioid, delta; Spiro Compounds; Vas Deferens	1998
Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety. Journal of medicinal chemistry, 1998, Jul-16, Volume: 41, Issue:15 Topics: Animals; Brain; Guinea Pigs; Ileum; Indoles; Ligands; Male; Mice; Morphinans; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship; Vas Deferens	1998
Beta-funaltrexamine discriminates between two subtypes of mu2-opioid receptors in electrically stimulated longitudinal muscle of guinea pig ileum. General pharmacology, 1998, Volume: 31, Issue:2 Topics: Acetylcholine; Animals; Binding, Competitive; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Endings; Receptors, Opioid, mu; Tetrodotoxin	1998
The involvement of the opioidergic system in the antinociceptive mechanism of action of antidepressant compounds. British journal of pharmacology, 1998, Volume: 124, Issue:4 Topics: Abdominal Muscles; Acetic Acid; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclobutanes; Dothiepin; Male; Maprotiline; Mice; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Neurotransmitter Uptake Inhibitors; Opioid Peptides; Pain Measurement; Paroxetine; Protease Inhibitors; Receptors, Opioid; Selective Serotonin Reuptake Inhibitors; Thiorphan	1998
7-Arylidenenaltrexones as selective delta1 opioid receptor antagonists. Journal of medicinal chemistry, 1998, Oct-08, Volume: 41, Issue:21 Topics: Animals; Benzylidene Compounds; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Structure-Activity Relationship; Tail; Vas Deferens	1998
delta Opioid affinity and selectivity of 4-hydroxy-3-methoxyindolomorphinan analogues related to naltrindole. Journal of medicinal chemistry, 1999, May-06, Volume: 42, Issue:9 Topics: Animals; Binding, Competitive; Brain; Guanosine 5'-O-(3-Thiotriphosphate); Ileum; In Vitro Techniques; Indoles; Ligands; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Rabbits; Receptors, Opioid, delta; Vas Deferens	1999
Naloxone blocks endomorphin-1 but not endomorphin-2 induced inhibition of tachykinergic contractions of guinea-pig isolated bronchus. British journal of pharmacology, 1999, Volume: 127, Issue:3 Topics: Analgesics, Opioid; Animals; Bronchi; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin A; Oligopeptides; Receptors, Opioid, mu; Tachykinins	1999
Interactions between cholecystokinin and opioids in the isolated guinea-pig ileum. British journal of pharmacology, 1999, Volume: 127, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphinans; Muscle Contraction; Naloxone; Naltrexone; Oligopeptides; Opioid Peptides; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Receptors, Opioid; Sincalide; Substance Withdrawal Syndrome	1999
BU48: a novel buprenorphine analog that exhibits delta-opioid-mediated convulsions but not delta-opioid-mediated antinociception in mice. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3 Topics: Analgesics, Opioid; Animals; Benzamides; Brain; Buprenorphine; Convulsants; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Pain Measurement; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Seizures; Vas Deferens	2000
Characterization of opioid receptors modulating neurogenic contractions of circular muscle from porcine ileum and evidence that delta- and kappa-opioid receptors are coexpressed in myenteric neurons. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1 Topics: Amino Acid Sequence; Animals; Electric Stimulation; Enkephalin, Leucine; Goats; Ileum; In Vitro Techniques; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naltrexone; Rabbits; Receptors, Opioid, delta; Receptors, Opioid, kappa; Swine	2001
Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene. British journal of pharmacology, 2001, Volume: 132, Issue:7 Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Genotype; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Morphine; Muscle Contraction; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens	2001
Transformation of a kappa-opioid receptor antagonist to a kappa-agonist by transfer of a guanidinium group from the 5'- to 6'-position of naltrindole. Journal of medicinal chemistry, 2001, Jun-21, Volume: 44, Issue:13 Topics: Animals; Cell Line; Cloning, Molecular; Guanidine; Guinea Pigs; Humans; In Vitro Techniques; Molecular Conformation; Muscle Contraction; Muscle, Smooth; Mutagenesis, Site-Directed; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid, kappa; Structure-Activity Relationship; Transfection	2001
Endogenous opiate receptor ligand: electrically induced release in the guinea pig ileum. Science (New York, N.Y.), 1977, Jan-28, Volume: 195, Issue:4276 Topics: Electric Stimulation; Ileum; Ligands; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Nerve Tissue Proteins; Neuromuscular Junction; Peptides; Receptors, Opioid; Stereoisomerism	1977
Genotype dependent response of morphine and methionine-enkephalin on the electrically induced contractions of the mouse vas deferens. Naunyn-Schmiedeberg's archives of pharmacology, 1978, Volume: 305, Issue:1 Topics: Animals; Electric Stimulation; Endorphins; Enkephalins; Genotype; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Muscle Contraction; Muscle, Smooth; Naltrexone; Vas Deferens	1978
The structure-action relationship and kinetics of some naloxone and naltrexone derivatives. Pharmacology, 1976, Volume: 14, Issue:1 Topics: Animals; Cyclazocine; Guinea Pigs; Ileum; Kinetics; Morphine; Morphine Derivatives; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Structure-Activity Relationship; Time Factors	1976
Involvement of opioid mechanisms in peripheral motor control of detrusor muscle. Pharmacology & toxicology, 1992, Volume: 71, Issue:3 Pt 1 Topics: Animals; Electric Stimulation; Enkephalins; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Humans; Indoles; Male; Morphinans; Morphine; Muscle Contraction; Muscles; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance P; Sympatholytics	1992
The mu-opioid activity of kappa-opioid receptor agonist compounds in the guinea pig ileum. European journal of pharmacology, 1992, Mar-03, Volume: 212, Issue:2-3 Topics: Animals; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nalorphine; Naltrexone; Phenazocine; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1992
Delta opioid antagonist activity and binding studies of regioisomeric isothiocyanate derivatives of naltrindole: evidence for delta receptor subtypes. Journal of medicinal chemistry, 1992, Oct-30, Volume: 35, Issue:22 Topics: Animals; Binding, Competitive; Brain; Guinea Pigs; In Vitro Techniques; Isomerism; Isothiocyanates; Male; Mice; Morphinans; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Structure-Activity Relationship; Thiocyanates	1992
Tyr-MIF-1 and hemorphin can act as opiate agonists as well as antagonists in the guinea pig ileum. Life sciences, 1992, Volume: 51, Issue:11 Topics: Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Hemoglobins; Ileum; In Vitro Techniques; Male; Molecular Sequence Data; Morphine; MSH Release-Inhibiting Hormone; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1992
The opioid activity and receptor selectivity of fluorinated Leu5 enkephalin analogues in vitro and in vivo. Journal of pharmacobio-dynamics, 1991, Volume: 14, Issue:2 Topics: Analgesics; Animals; Enkephalin, Leucine; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Male; Mice; Mice, Inbred Strains; Morphinans; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid	1991
Opioid receptor activity of GI 87084B, a novel ultra-short acting analgesic, in isolated tissues. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2 Topics: Alkylation; Animals; Enkephalin, Leucine; Guinea Pigs; Ileum; Kinetics; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Remifentanil; Vas Deferens	1991
Role of the spacer in conferring kappa opioid receptor selectivity to bivalent ligands related to norbinaltorphimine. Journal of medicinal chemistry, 1991, Volume: 34, Issue:4 Topics: Animals; Binding, Competitive; In Vitro Techniques; Indicators and Reagents; Kinetics; Ligands; Male; Molecular Conformation; Molecular Structure; Muscle Contraction; Muscle, Smooth; Naltrexone; Receptors, Opioid; Receptors, Opioid, kappa; Structure-Activity Relationship	1991
The opioid receptor selectivity for trimebutine in isolated tissues experiments and receptor binding studies. Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:7 Topics: Animals; Drug Tolerance; Guinea Pigs; Ileum; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Rabbits; Receptors, Opioid; Trimebutine; Vas Deferens	1990
Evidence that the agonist action of dynorphin A(1-8) in the guinea-pig myenteric-plexus may be mediated partly through conversion to [Leu5]enkephalin. British journal of pharmacology, 1990, Volume: 101, Issue:3 Topics: Animals; Dynorphins; Enkephalin, Leucine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Myenteric Plexus; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid	1990
In vivo and in vitro investigation of naltrindole, a delta-opioid antagonist. Proceedings of the Western Pharmacology Society, 1990, Volume: 33 Topics: Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Indoles; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphinans; Morphine; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Reaction Time; Receptors, Opioid; Receptors, Opioid, delta; Vas Deferens	1990
Action of naloxone on myenteric neurons removed from morphine-treated guinea pigs. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:3 Topics: Acetylcholine; Action Potentials; Animals; Endorphins; Guinea Pigs; Ileum; In Vitro Techniques; Magnesium; Morphine; Muscle Contraction; Myenteric Plexus; Naloxone; Naltrexone; Substance P	1988
Naltrindole, a highly selective and potent non-peptide delta opioid receptor antagonist. European journal of pharmacology, 1988, Jan-27, Volume: 146, Issue:1 Topics: Animals; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Male; Mice; Morphinans; Muscle Contraction; Muscle, Smooth, Vascular; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid; Receptors, Opioid, delta; Vas Deferens	1988
Buprenorphine is a potent kappa-opioid receptor antagonist in pigeons and mice. European journal of pharmacology, 1988, Jul-14, Volume: 151, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Buprenorphine; Columbidae; Male; Mice; Muscle Contraction; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Reinforcement Schedule	1988
Lack of evidence for epsilon-opioid receptors in the rat vas deferens. European journal of pharmacology, 1988, Sep-23, Volume: 154, Issue:3 Topics: Animals; Calcium; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Naltrexone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Vas Deferens	1988
Prolonged in vivo antagonism of central mu- and delta-opioid receptor activity by beta-funal trexamine. Life sciences, 1985, Apr-08, Volume: 36, Issue:14 Topics: Animals; Female; Injections, Intraventricular; Injections, Spinal; Muscle Contraction; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Urinary Bladder	1985
Pre-incubation of guinea-pig myenteric plexus with beta-funaltrexamine: discrepancy between binding assays and bioassays. British journal of pharmacology, 1985, Volume: 85, Issue:3 Topics: Animals; Binding, Competitive; Brain; Cricetinae; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Naltrexone; Narcotic Antagonists; Rabbits; Rats; Receptors, Opioid	1985
Activity of mu- and delta-selective opioid agonists in the guinea pig ileum preparation: differentiation into peptide and nonpeptide classes with beta-funaltrexamine. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:2 Topics: Animals; Endorphins; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nalorphine; Naloxone; Naltrexone; Narcotics; Peptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship	1986
Synthesis and opioid antagonist potencies of naltrexamine bivalent ligands with conformationally restricted spacers. Journal of medicinal chemistry, 1986, Volume: 29, Issue:9 Topics: Animals; Biological Assay; Chemical Phenomena; Chemistry; Cyclazocine; Endorphins; Ethylketocyclazocine; Guinea Pigs; Ileum; Molecular Conformation; Morphine; Muscle Contraction; Naltrexone; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship	1986
Use of beta-funaltrexamine to determine mu opioid receptor involvement in the analgesic activity of various opioid ligands. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Biological Assay; Buprenorphine; Butorphanol; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Etorphine; Fentanyl; Methadone; Mice; Morphine; Muscle Contraction; Nalbuphine; Nalorphine; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, mu	1987
Opioid agonist and antagonist activities of monofunctional nitrogen mustard analogues of beta-chlornaltrexamine. Journal of medicinal chemistry, 1987, Volume: 30, Issue:5 Topics: Animals; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Naltrexone; Nitrogen Mustard Compounds; Receptors, Opioid; Vas Deferens	1987
Diprenorphine has agonist activity at opioid kappa-receptors in the myenteric plexus of the guinea-pig ileum. European journal of pharmacology, 1987, May-07, Volume: 137, Issue:1 Topics: Animals; Cricetinae; Diprenorphine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphinans; Muscle Contraction; Myenteric Plexus; Naltrexone; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens	1987
Reversal by beta-funaltrexamine and 16-methyl cyprenorphine of the antinociceptive effects of opioid agonists in the mouse and guinea-pig. Neuropharmacology, 1988, Volume: 27, Issue:8 Topics: Abdomen; Animals; Guinea Pigs; Male; Mice; Morphinans; Muscle Contraction; Naltrexone; Narcotic Antagonists; Narcotics; Nociceptors; Pain	1988