naltrexone and Multiple Sclerosis

naltrexone has been researched along with Multiple Sclerosis in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (21.05)29.6817
2010's12 (63.16)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Arnett, PA; McLaughlin, PJ; Odom, LB; Orehek, S; Thomas, GA; Zagon, IS1
Fishman, MA; Kim, PS1
Barrientos, RM; Clements, MA; Duran-Malle, JC; Harris, KM; Kwilasz, AJ; Larson, TA; Litwiler, ST; Maier, SF; Mitten, EH; Rice, KC; Schrama, AEW; Todd, LS; Van Dam, AM; Wang, X; Watkins, LR1
Ludwig, MD; McLaughlin, PJ; Zagon, IS2
Raknes, G; Småbrekke, L1
Berlau, DJ; Patten, DK; Schultz, BG1
Feng, J; Griffin, N; Li, Z; Shan, F; You, Y1
McLaughlin, PJ; Zagon, IS1
Hammer, LA; McLaughlin, PJ; Waldner, H; Zagon, IS1
McLaughlin, PJ; Oh, KH; Turel, AP; Zagon, IS1
Handberg, G; Plesner, KB; Vægter, HB1
McLaughlin, PJ; Rahn, KA; Turel, AP; Zagon, IS1
Cree, BA; Goodin, DS; Kornyeyeva, E1
Giverhaug, T; Raknes, G1
Holmøy, T1
Agrawal, YP1
Good, P1
Patel, PN1

Reviews

5 review(s) available for naltrexone and Multiple Sclerosis

ArticleYear
Low-Dose Naltrexone for Chronic Pain: Update and Systemic Review.
    Current pain and headache reports, 2020, Aug-26, Volume: 24, Issue:10

    Topics: Chronic Pain; Fibromyalgia; Humans; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders

2020
The Safety and Efficacy of Low-Dose Naltrexone in the Management of Chronic Pain and Inflammation in Multiple Sclerosis, Fibromyalgia, Crohn's Disease, and Other Chronic Pain Disorders.
    Pharmacotherapy, 2018, Volume: 38, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Chronic Pain; Crohn Disease; Dose-Response Relationship, Drug; Fibromyalgia; Humans; Inflammation; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Quality of Life

2018
Low-dose naltrexone (LDN): A promising treatment in immune-related diseases and cancer therapy.
    International immunopharmacology, 2018, Volume: 61

    Topics: Analgesics, Opioid; Animals; Autoimmunity; Crohn Disease; Drug Dosage Calculations; Humans; Immunologic Factors; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Neoplasms; Off-Label Use; Receptors, Opioid; Substance Abuse Treatment Centers

2018
Intermittent blockade of OGFr and treatment of autoimmune disorders.
    Experimental biology and medicine (Maywood, N.J.), 2018, Volume: 243, Issue:17-18

    Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Humans; Mice; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Receptors, Opioid

2018
[Low dose naltrexone for treatment of pain].
    Ugeskrift for laeger, 2015, Oct-09, Volume: 177, Issue:43

    Topics: Analgesics, Opioid; Crohn Disease; Fibromyalgia; Humans; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Pain

2015

Trials

1 trial(s) available for naltrexone and Multiple Sclerosis

ArticleYear
Pilot trial of low-dose naltrexone and quality of life in multiple sclerosis.
    Annals of neurology, 2010, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Aged; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Mood Disorders; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Pilot Projects; Placebos; Quality of Life; Young Adult

2010

Other Studies

13 other study(ies) available for naltrexone and Multiple Sclerosis

ArticleYear
Low-dose naltrexone reduced anxiety in persons with multiple sclerosis during the COVID-19 pandemic.
    International immunopharmacology, 2022, Volume: 113, Issue:Pt B

    Topics: Anxiety; COVID-19 Drug Treatment; Humans; Multiple Sclerosis; Naltrexone; Pandemics

2022
Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone.
    Behavioural brain research, 2021, 01-01, Volume: 396

    Topics: Animals; Behavior, Animal; Cells, Cultured; Conditioning, Classical; Encephalomyelitis, Autoimmune, Experimental; Fear; Hippocampus; Inflammation; Male; Memory Disorders; Mice; Microglia; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 2; Toll-Like Receptor 4

2021
Featured Article: Serum [Met
    Experimental biology and medicine (Maywood, N.J.), 2017, Volume: 242, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Animals; Biomarkers; Encephalomyelitis, Autoimmune, Experimental; Enkephalin, Methionine; Female; Humans; Male; Mice, Inbred C57BL; Middle Aged; Multiple Sclerosis; Naltrexone; Neuroprotective Agents; Serum; Treatment Outcome; Volunteers; Young Adult

2017
Low dose naltrexone in multiple sclerosis: Effects on medication use. A quasi-experimental study.
    PloS one, 2017, Volume: 12, Issue:11

    Topics: Dose-Response Relationship, Drug; Humans; Multiple Sclerosis; Naltrexone; Norway

2017
Featured Article: Modulation of the OGF-OGFr pathway alters cytokine profiles in experimental autoimmune encephalomyelitis and multiple sclerosis.
    Experimental biology and medicine (Maywood, N.J.), 2018, Volume: 243, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Animals; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Enkephalin, Methionine; Female; Glatiramer Acetate; Humans; Immunosuppressive Agents; Male; Mice, Inbred C57BL; Middle Aged; Multiple Sclerosis; Naltrexone; Receptors, Opioid

2018
Opioid growth factor and low-dose naltrexone impair central nervous system infiltration by CD4 + T lymphocytes in established experimental autoimmune encephalomyelitis, a model of multiple sclerosis.
    Experimental biology and medicine (Maywood, N.J.), 2016, Volume: 241, Issue:1

    Topics: Animals; CD4-Positive T-Lymphocytes; Central Nervous System; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enkephalin, Methionine; Female; Mice; Multiple Sclerosis; Naltrexone; Narcotic Antagonists

2016
Low Dose Naltrexone for Treatment of Multiple Sclerosis: A Retrospective Chart Review of Safety and Tolerability.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Retrospective Studies; Treatment Outcome; Young Adult

2015
Endogenous opioids regulate expression of experimental autoimmune encephalomyelitis: a new paradigm for the treatment of multiple sclerosis.
    Experimental biology and medicine (Maywood, N.J.), 2009, Volume: 234, Issue:11

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Female; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Naltrexone; Nervous System

2009
[Naltrexone--high expectations to low dosages].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2011, May-06, Volume: 131, Issue:8

    Topics: Crohn Disease; Dose-Response Relationship, Drug; Humans; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Treatment Outcome

2011
[Research on low dosage naltrexone].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2011, Jul-01, Volume: 131, Issue:13-14

    Topics: Dose-Response Relationship, Drug; Humans; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Research Support as Topic

2011
Low dose naltrexone therapy in multiple sclerosis.
    Medical hypotheses, 2005, Volume: 64, Issue:4

    Topics: Apoptosis; Dose-Response Relationship, Drug; Humans; Multiple Sclerosis; Naltrexone; Oxidative Stress

2005
Low-dose naltrexone for multiple sclerosis and autism: does its benefit reveal a common cause?
    Medical hypotheses, 2006, Volume: 67, Issue:3

    Topics: Anti-Inflammatory Agents; Autistic Disorder; Dose-Response Relationship, Drug; Humans; Models, Biological; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Nitric Oxide Synthase Type II

2006
Low-dose naltrexone for treatment of multiple sclerosis: clinical trials are needed.
    The Annals of pharmacotherapy, 2007, Volume: 41, Issue:9

    Topics: Clinical Trials as Topic; Humans; Multiple Sclerosis; Naltrexone; Narcotic Antagonists

2007