naltrexone and Liver Diseases

naltrexone has been researched along with Liver Diseases in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Askgaard, G; Nielsen, AS; Thiele, M1
Ayyala, D; Bottyan, T; Dodge, JL; Gonzalez, JL; Han, H; Pimienta, M; Stager, K; Stolz, A; Terrault, NA; Tien, C; Yoo, J1
Du, Y; Sun, L; von Moltke, L; Yagoda, S1
Barter, Z; Rowland Yeo, K; Sun, L; von Moltke, L1
Du, J; Liang, R; Tang, B; Wang, H; Wang, L; Yuan, P; Zhang, Y1
Dilzer, SC; Dong, Q; Dunbar, JL; Ehrich, EW; Lasseter, KC; Silverman, BL; Turncliff, RZ1
Dixon, R; Frye, RF; Matzke, GR; Rabinovitz, M; Schade, R1

Reviews

1 review(s) available for naltrexone and Liver Diseases

ArticleYear
Treatment of alcohol use disorder in patients with liver disease.
    Current opinion in pharmacology, 2022, Volume: 62

    Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Humans; Liver Diseases; Naltrexone; Narcotic Antagonists; Treatment Outcome

2022

Trials

2 trial(s) available for naltrexone and Liver Diseases

ArticleYear
Effect of hepatic and renal impairment on the pharmacokinetics of olanzapine and samidorphan given in combination as a bilayer tablet.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Liver Diseases; Male; Middle Aged; Naltrexone; Olanzapine; Renal Insufficiency; Tablets; Young Adult

2019
Pharmacokinetics of long-acting naltrexone in subjects with mild to moderate hepatic impairment.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:11

    Topics: Adult; Aged; Delayed-Action Preparations; Female; Humans; Liver Diseases; Male; Middle Aged; Naltrexone; Narcotic Antagonists

2005

Other Studies

5 other study(ies) available for naltrexone and Liver Diseases

ArticleYear
Naltrexone for alcohol use disorder: Hepatic safety in patients with and without liver disease.
    Hepatology communications, 2022, Volume: 6, Issue:12

    Topics: Adult; Alcoholism; Humans; Liver Cirrhosis; Liver Diseases; Naltrexone; Retrospective Studies

2022
Using physiologically-based pharmacokinetic modeling for predicting the effects of hepatic impairment on the pharmacokinetics of olanzapine and samidorphan given as a combination tablet.
    CPT: pharmacometrics & systems pharmacology, 2021, Volume: 10, Issue:9

    Topics: Aged; Antipsychotic Agents; Drug Combinations; Female; Humans; Liver Diseases; Male; Middle Aged; Models, Biological; Naltrexone; Narcotic Antagonists; Olanzapine; Severity of Illness Index; Tablets

2021
Activation of the δ-opioid receptor inhibits serum deprivation-induced apoptosis of human liver cells via the activation of PKC and the mitochondrial pathway.
    International journal of molecular medicine, 2011, Volume: 28, Issue:6

    Topics: Apoptosis; bcl-2-Associated X Protein; Cytochromes c; Enkephalin, Leucine-2-Alanine; Gene Expression; Hepatocytes; Humans; Liver; Liver Diseases; Membrane Potential, Mitochondrial; Mitochondria; Naltrexone; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Receptors, Opioid, delta; Serum; Signal Transduction; Stress, Physiological; Tumor Cells, Cultured

2011
Nalmefene--a long-acting injectable opioid antagonist.
    The Medical letter on drugs and therapeutics, 1995, Oct-27, Volume: 37, Issue:960

    Topics: Clinical Trials as Topic; Costs and Cost Analysis; Dose-Response Relationship, Drug; Drug Overdose; Humans; Injections, Intravenous; Kidney Failure, Chronic; Liver Diseases; Naltrexone; Narcotic Antagonists; Postoperative Care; Respiratory Insufficiency

1995
Effects of liver disease on the disposition of the opioid antagonist nalmefene.
    Clinical pharmacology and therapeutics, 1997, Volume: 61, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Case-Control Studies; Female; Galactose; Glucuronates; Humans; Injections, Intravenous; Liver Diseases; Male; Matched-Pair Analysis; Middle Aged; Naltrexone; Narcotic Antagonists; Severity of Illness Index

1997